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Compound Formula Rehmannia alleviates levodopainduced dyskinesia in Parkinson's disease 被引量:9
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作者 Long Teng Fang Hong +2 位作者 Chenguang Zhang Jiancheng He Haiying Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第4期407-412,共6页
Compound Formula Rehmannia has been shown to be clinically effective in treating Parkinson's disease and levodopa-induced dyskinesia; however, the mechanisms remain unclear. In this study, we established a model of P... Compound Formula Rehmannia has been shown to be clinically effective in treating Parkinson's disease and levodopa-induced dyskinesia; however, the mechanisms remain unclear. In this study, we established a model of Parkinson's disease dyskinesia in rats, and treated these animals with Compound Formula Rehmannia. Compound Formula Rehmannia inhibited the increase in mRNA expression of N-methyl-D-aspartate receptor subunits 1 and 2 and excitatory amino acid neurotransmitter genes, and it inhibited the reduction in expression of γ-aminobutyric acid receptor B1, an inhibitory amino acid neurotransmitter gene, in the corpus striatum. In addition, Compound Formula Rehmannia alleviated dyskinesia symptoms in the Parkinson's disease rats. These experimental findings indicate that Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease by modulating neurotransmitter signaling in the corpus striatum. 展开更多
关键词 nerve regeneration traditional Chinese medicine Parkinson's disease DYSKINESIA excitato-ry amino acid inhibitory amino acid NEUROBEHAVIOR Compound formula Rehmannia NSFC grant neural regeneration
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奥巴马政府教师素质经费改革计划探析
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作者 石雷 《长春师范大学学报(人文社会科学版)》 2012年第1期131-132,共2页
在奥巴马政府发布的美国2011年财政预算中,关于教师素质方面的经费预算计划具有三重性特点:一方面增加以绩效为基础的教师素质经费预算,引入竞争机制,激励教师的专业发展;另一方面减少常规的教师素质经费预算,避免经费的低效率使用;并... 在奥巴马政府发布的美国2011年财政预算中,关于教师素质方面的经费预算计划具有三重性特点:一方面增加以绩效为基础的教师素质经费预算,引入竞争机制,激励教师的专业发展;另一方面减少常规的教师素质经费预算,避免经费的低效率使用;并且提供了预备基金,作为应急之需。 展开更多
关键词 美国2011年预算 教师素质 绩效经费 常规经费 预备基金
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关于赠与成份GE的三个问题
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作者 郑策 《辽宁石油化工大学学报》 CAS 1994年第4期82-87,共6页
探讨了赠与成份含义的实质,推导出赠与成份计算公式,鉴别一些公式及式中字母经济含义的正误.并在此基础上进一步对赠与成份公式加以修正,以反映贷款真实的优惠程度.
关键词 概念 公式 辨识/赠与成份
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