Effectiveness of fractional CO2 laser in women with stress urinary incontinence

BACKGROUND： Stress urinary incontinence （SUI） is a relatively common disorder that significantly affects the quality of life. Many conservative and surgical treatment methods have been recommended for SUI, but they have major limitations. AIMS： To assess the use of the CO2 fractional laser in the treatment of SUI. METHODS： This clinical trial included 55 patients with confirmed SUI. Patients underwent fractional CO2 laser treatment 3 times at 30-day intervals. Data on age, smoking history, sexual activity, menopause, and history of hormone replacement therapy （HRT） were collected. Response to treatment was assessed by SUI severity and the level of sexual satisfaction was assessed using the visual analog scale （VAS）. Patients were evaluated at 3 different time points： before treatment, and 45 days and 6 months after the last laser treatment. RESULTS： The mean patient age was 44.4±11.4 years （range： 28 to 68 years）. Smoking history was positive in 6 patients （9.1%）; 19 （54.3%） were menopausal on HRT. The SUI severity score at baseline （before treatment） was 8.56±0.62 and decreased to 2.28 6 months after treatment （p 〈 0.0001）. The sexual satisfaction score was 3 ± 0.94 at baseline and increased to 7.87±0.93 6 months after treatment （day 180） （p 〈 0.0001, slope = ＋ 2.2） CONCLUSION： Our findings are in line with a previous study that showed the value of transvaginal CO2 fractional laser treatment for alleviation of SUI symptoms and its potential as an alternative treatment. We also observed improved sexual satisfaction in SUI patients.

Observation on clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment

Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.

Clinical study of treatment of facial scar with ultrapulse CO2 laser and Erbium fractional laser

Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed