Model initialization is a key process of climate predictions using dynamical models. In this study, the authors evaluated the performances of two distinct initialization approaches--anomaly and full-field initializati...Model initialization is a key process of climate predictions using dynamical models. In this study, the authors evaluated the performances of two distinct initialization approaches--anomaly and full-field initializations--in ENSO predictions conducted using the IAP-DecPreS near-term climate prediction system developed by the Institute of Atmospheric Physics (lAP). IAP-DecPreS is composed of the FGOALS-s2 coupled general circulation model and a newly developed ocean data assimilation scheme called'ensemble optimal interpolation-incremental analysis update' (EnOI-IAU). It was found that, for IAP-DecPreS, the hindcast runs using the anomaly initialization have higher predictive skills for both conventional ENSO and El Nino Modoki, as compared to using the full-field initialization. The anomaly hindcasts can predict super El Nino/La Nina 10 months in advance and have good skill for most moderate and weak ENSO events about 4-7 months in advance.The predictive skill of the anomaly hindcasts for El Nino Modoki is close to that for conventional ENSO. On the other hand, the anomaly hindcasts at 1- and 4-month lead time can reproduce the major features of large-scale patterns of sea surface temperature, precipitation and atmospheric circulation anomalies during conventional ENSO and El Nino Modoki winter.展开更多
OBJECTIVE Different mammographic features are probably predictive of different prognosis. However, ambiguity still exists in understanding the relationship between them. In resent years, digital mammography has been a...OBJECTIVE Different mammographic features are probably predictive of different prognosis. However, ambiguity still exists in understanding the relationship between them. In resent years, digital mammography has been available for clinical use which has led to a revolution in the resolving of images and an increase in early-stage breast cancer detection. Based on the above knowledge, this study was performed to evaluate the relationship between full-field digital mammographic features and clinicopathologic characteristics in breast cancer. METHODS Digital mammograms of 176 patients with pathologically proven breast cancer were reviewed. Also, clinical and pathologic records (histological types and axillary lymph nodes status) were retrospectively examined. RESULTS Most of the patients with a solitary microcalcification were young women under the age of 50(84.4%), but the majority of the patients with microcalcifications complicated by a mass were elderly women. Microcalcifications detected by mammography occurred frequently in ductal carcinoma in situ (28.1%) and in early invasive carcinoma (15.6%). Breast cancers with expression of microcalcifications combined with a spiculate mass had a high metastatic rate of axillary lymph nodes (69.4%). A high metastatic rate of axillary lymph nodes was also found in the patients with solitary worm-like microcalcifications (57.1%), solitary spiculate mass (53.7%) and solitary non-worm-like microcalcifications (44.4%). Simple worm-like microcalcifications accompanied with metastasis of 4 to 9 axillary lymph nodes occurred in 42.9% of the(6/14) cases. The patients with microcalcifications combined by a spiculate mass and with metastasis of 4 to 9 axillary lymph nodes accounted for 27.8% (10/36) of the cases, and those with metastases of 10 and over accounted for 16.7% (6/36). CONCLUSION Solitary microcalcifications occur frequently in young women and are usually associated with early breast cancer. There is a close relationship between worm-like microcalcifications, a spiculate mass and positive metastases of axillary lymph nodes, which are an index of poor prognosis.展开更多
This paper presents analytical solutions for full-field radiation in magnetoelectric(ME)antennas,considering a fully magnetoelastic coupled constitutive relation.A nonlinear converse ME coupling model is established,i...This paper presents analytical solutions for full-field radiation in magnetoelectric(ME)antennas,considering a fully magnetoelastic coupled constitutive relation.A nonlinear converse ME coupling model is established,incorporating mechanical,electric,and magnetic variables with generalized Maxwell equations.This model emphasizes the essence of ME antennas,where radiation is achieved through strain/stress-mediated coupling between different phases.The magnetic flux density and electric displacement obtained from the model are used as sources to solve the full-field radiations of ME antennas.The proposed model is validated through existing experiments and simulations,demonstrating that the radiation performance of ME antennas is strongly influenced by nonlinear magneto-elastic coupling.The material parameters and magnetic bias significantly impact the magnetic flux density and far-field radiation due to the nonlinear magnetization process.The study reveals the mechanisms behind enhanced working bandwidth and frequency tuning by examining the frequency response of the radiation impedance with material parameters.By adjusting the initial magnetization rate,saturation magnetostriction,and saturation magnetization,the radiation efficiency/gain can be increased by 340%,108%,and 112%respectively.This model enhances our understanding of the full-field radiation of ME antennas and provides a foundation for designing tunable ME antennas.展开更多
目的 探讨单体位[头尾位(craniocaudal, CC)或内外侧斜位(mediolateral oblique, MLO)]数字化乳腺断层合成技术(digital breast tomosynthesis,DBT)联合全视野数字化乳腺X线摄影(full-fild digital mammography,FFDM)检查对乳腺癌的检...目的 探讨单体位[头尾位(craniocaudal, CC)或内外侧斜位(mediolateral oblique, MLO)]数字化乳腺断层合成技术(digital breast tomosynthesis,DBT)联合全视野数字化乳腺X线摄影(full-fild digital mammography,FFDM)检查对乳腺癌的检出率和诊断效能。方法 选取141例乳腺病变患者影像学资料,患者同时行乳腺DBT和FFDM检查。由2位放射科诊断医师分别对患者DBT图像进行单体位和双体位(CC+MLO)阅片并联合FFDM,以病理结果为金标准。分析单体位和双体位DBT检查联合FFDM检查对患者乳腺良恶性病灶的检出率及诊断效能。结果 141例患者按照ACR2013版BI-RADS系统分类标准:a类3例、b类40例、c类84例、d类14例。根据BI-RADS评级标准,2位放射科诊断医师采用四种诊断方式(DBT-CC,DBT-MLO及双体位DBT分别联合FFDM及单独FFDM)进行诊断。结论 采用DBT+FFDM的阅片方式无论是单体位还是双体位的结果假阳性率及假阴性率均低于FFDM,诊断的准确度、特异度及灵敏度均高于FFDM,对高/低年资诊断医师FFDM+DBT双体位的诊断效能高于单体位,在FFDM+DBT-CC和FFDM+DBT-MLO单体位之间准确度、灵敏度和特异度MLO均高于CC位。展开更多
基金jointly supported by the National Key Research and Development Program of China(grant number2017YFA0604201)the National Natural Science Foundation of China(grant numbers.41661144009 and 41675089)the R&D Special Fund for Public Welfare Industry(meteorology)(grant number GYHY201506012)
文摘Model initialization is a key process of climate predictions using dynamical models. In this study, the authors evaluated the performances of two distinct initialization approaches--anomaly and full-field initializations--in ENSO predictions conducted using the IAP-DecPreS near-term climate prediction system developed by the Institute of Atmospheric Physics (lAP). IAP-DecPreS is composed of the FGOALS-s2 coupled general circulation model and a newly developed ocean data assimilation scheme called'ensemble optimal interpolation-incremental analysis update' (EnOI-IAU). It was found that, for IAP-DecPreS, the hindcast runs using the anomaly initialization have higher predictive skills for both conventional ENSO and El Nino Modoki, as compared to using the full-field initialization. The anomaly hindcasts can predict super El Nino/La Nina 10 months in advance and have good skill for most moderate and weak ENSO events about 4-7 months in advance.The predictive skill of the anomaly hindcasts for El Nino Modoki is close to that for conventional ENSO. On the other hand, the anomaly hindcasts at 1- and 4-month lead time can reproduce the major features of large-scale patterns of sea surface temperature, precipitation and atmospheric circulation anomalies during conventional ENSO and El Nino Modoki winter.
文摘OBJECTIVE Different mammographic features are probably predictive of different prognosis. However, ambiguity still exists in understanding the relationship between them. In resent years, digital mammography has been available for clinical use which has led to a revolution in the resolving of images and an increase in early-stage breast cancer detection. Based on the above knowledge, this study was performed to evaluate the relationship between full-field digital mammographic features and clinicopathologic characteristics in breast cancer. METHODS Digital mammograms of 176 patients with pathologically proven breast cancer were reviewed. Also, clinical and pathologic records (histological types and axillary lymph nodes status) were retrospectively examined. RESULTS Most of the patients with a solitary microcalcification were young women under the age of 50(84.4%), but the majority of the patients with microcalcifications complicated by a mass were elderly women. Microcalcifications detected by mammography occurred frequently in ductal carcinoma in situ (28.1%) and in early invasive carcinoma (15.6%). Breast cancers with expression of microcalcifications combined with a spiculate mass had a high metastatic rate of axillary lymph nodes (69.4%). A high metastatic rate of axillary lymph nodes was also found in the patients with solitary worm-like microcalcifications (57.1%), solitary spiculate mass (53.7%) and solitary non-worm-like microcalcifications (44.4%). Simple worm-like microcalcifications accompanied with metastasis of 4 to 9 axillary lymph nodes occurred in 42.9% of the(6/14) cases. The patients with microcalcifications combined by a spiculate mass and with metastasis of 4 to 9 axillary lymph nodes accounted for 27.8% (10/36) of the cases, and those with metastases of 10 and over accounted for 16.7% (6/36). CONCLUSION Solitary microcalcifications occur frequently in young women and are usually associated with early breast cancer. There is a close relationship between worm-like microcalcifications, a spiculate mass and positive metastases of axillary lymph nodes, which are an index of poor prognosis.
基金supported by the Natural Science Foundation of Shaanxi Province(Grant No.2024JC-YBMS-069)the Fundamental Research Funds for the Central Universities and the Innovation Fund of Xidian University(Grant Nos.ZYTS24026 and YJSJ24001).
文摘This paper presents analytical solutions for full-field radiation in magnetoelectric(ME)antennas,considering a fully magnetoelastic coupled constitutive relation.A nonlinear converse ME coupling model is established,incorporating mechanical,electric,and magnetic variables with generalized Maxwell equations.This model emphasizes the essence of ME antennas,where radiation is achieved through strain/stress-mediated coupling between different phases.The magnetic flux density and electric displacement obtained from the model are used as sources to solve the full-field radiations of ME antennas.The proposed model is validated through existing experiments and simulations,demonstrating that the radiation performance of ME antennas is strongly influenced by nonlinear magneto-elastic coupling.The material parameters and magnetic bias significantly impact the magnetic flux density and far-field radiation due to the nonlinear magnetization process.The study reveals the mechanisms behind enhanced working bandwidth and frequency tuning by examining the frequency response of the radiation impedance with material parameters.By adjusting the initial magnetization rate,saturation magnetostriction,and saturation magnetization,the radiation efficiency/gain can be increased by 340%,108%,and 112%respectively.This model enhances our understanding of the full-field radiation of ME antennas and provides a foundation for designing tunable ME antennas.