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The Influence of Mesoscopic Characteristics of Mineral Powders Fillers on the Rutting Factor(G^(*)/sinδ)of Asphalt Mortar
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作者 LIAO Jun DENG Tao +6 位作者 GONG Hongwei LI Zhen TANG Yongtao CHEN Kai SHI Lei QIAN Xiaolong DONG Qian 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2023年第5期1118-1125,共8页
This study aims to investigate the efiect of the mesoscopic characteristics of mineral powder fillers on the rutting resistance of asphalt mortar.Extraction and sieving tests were used to obtain the buton rock asphalt... This study aims to investigate the efiect of the mesoscopic characteristics of mineral powder fillers on the rutting resistance of asphalt mortar.Extraction and sieving tests were used to obtain the buton rock asphalt(BRA)ash with particle size smaller than 0.075 mm,which is consistent with that of the conventional mineral powder.The mesoscopic characteristics of BRA ash and conventional mineral powder were measured by SEM image analysis and the osmotic free pressure water method.Mesoscopic structure models of structural and free asphalts in mortar were obtained.The 70#matrix asphalt was used to prepare two kinds of asphalt mortar with BRA ash and conventional mineral powders fillers.The rutting factor of the two asphalt mortars was tested by dynamic shear test(DSR).Test results show that the ash extracted from BRA has a similar mesoscopic classification with the conventional mineral powder.Still,its fractal dimensions are larger,indicating the particles in BRA ash have more complex shapes and rougher surfaces,which is beneficial for forming structural asphalt and subsequently increasing the rutting factor(G*/sinδ),i e,improving the rutting resistance of the asphalt mortar. 展开更多
关键词 asphalt mortar mineral powder fllers mesoscopic characteristic rutting factor(g*/sinδ)
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Energy Spectra,g Factors and Their Pressure—Induced and /or Thermal Shifts of SrTiO3:Cr^3+ and SrTiO3:Mn^4+ I:energy Spectra and g Factors at Normal Pressure 被引量:1
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作者 ZHANGJi-Ping MADong-Ping 《Communications in Theoretical Physics》 SCIE CAS CSCD 2001年第4期491-496,共6页
With the strong-field scheme and cubic bases, the complete d<SUP>3</SUP> energy matrix in a tetragonally distorted cubic-field has been constructed. By diagonalizing this matrix, the energy spectra of SrTi... With the strong-field scheme and cubic bases, the complete d<SUP>3</SUP> energy matrix in a tetragonally distorted cubic-field has been constructed. By diagonalizing this matrix, the energy spectra of SrTiO<SUB>3</SUB>:Cr<SUP>3+</SUP> and SrTiO<SUB>3</SUB>:Mn<SUP>4+</SUP> at normal pressure and various temperatures have been calculated. Correspondingly, the FORTRAN program calculating the g factor of the ground state has been worked out. By using the program and the wavefunction obtained from diagonalizing the complete energy matrix, the g factors of the ground state of SrTiO<SUB>3</SUB>:Cr<SUP>3+</SUP> and SrTiO<SUB>3</SUB>:Mn<SUP>4+</SUP> at normal pressure and room temperature have been evaluated. The calculated results are in good agreement with the optical-spectral and EPR experimental data. The comparison and analysis of the results of two crystals have been made. It is demonstrated that the covalency of the bonding between Mn<SUP>4+</SUP> and ligands (O<SUP>2-</SUP>) in SrTiO<SUB>3</SUB>:Mn<SUP>4+</SUP> is stronger than the one of the bonding between Cr<SUP>3+</SUP> and ligands (O<SUP>2-</SUP>) in SrTiO<SUB>3</SUB>:Cr<SUP>3+</SUP>. It is shown that the obtained wavefunctions and values of parameters are reasonable. 展开更多
关键词 crystal fields energy spectrum optical properties g factors COVALENCY
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Mobilization of Peripheral Blood Stem Cells Using Regimen Combining Docetaxel with Granulocyte Colony-stimulating Factor in Breast Cancer Patients 被引量:4
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作者 Jing Yu Jun Ren +8 位作者 Li-jun Di Guo-hong Song Yu-lin Zhu Jie Zhang Xu Liang Li Che Han-fang Jiang Jun Jia Chun-rong Zhang 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2011年第1期49-53,共5页
Objective:To evaluate the effectiveness and safety of the mobilization of peripheral blood hematopoietic stem cells by combining docetaxel with granulocyte colony-stimulating factor(G-CSF) in breast cancer patients... Objective:To evaluate the effectiveness and safety of the mobilization of peripheral blood hematopoietic stem cells by combining docetaxel with granulocyte colony-stimulating factor(G-CSF) in breast cancer patients.Methods:A total of 57 breast cancer patients were treated with docetaxel 120 mg/m2.When the white blood cell(WBC) count decreased to 1.0×109/L,patients were given G-CSF 5-g/kg daily by subcutaneous injection until the end of apheresis.Peripheral blood mononuclear cells(MNC) were isolated by Cobe Spectra Apheresis System.The percentage of CD34+ cell was assayed by flow cytometry.Results:At a median 6 of days(range 3-8) after the administration of docetaxel,the median WBC count decreased to 1.08×109/L(range 0.20-2.31).The median duration of G-CSF mobilization was 3 days(range 2-7).The MNC collection was conducted 8-12 days(median 10 days) after docetaxel treatment.The median MNC was 5.35×108/kg(range 0.59-14.07),the median CD34+ cell count was 2.43×106/kg(range 0.16-16.69).The CD34+ cell count was higher than 1.00×106/kg in 47 of 57 cases(82.46%) and higher than 2.00×106/kg in 36 cases(63.16%).The CD34+ cell count was higher than 2.00×106/kg in 27 collections(23.68%).The MNC count and the CD34+ cell count were correlated with the bottom of WBC after docetaxel chemotherapy(r=0.364,0.502,P=0.005,0.000).The CD34+ cell count was correlated with the MNC count(r=0.597,P=0.000).The mobilization and apheresis were well tolerated in all patients.Mild perioral numbness and numbness of hand or feet were observed in 3 cases.No serious adverse events were reported.Conclusion:Mobilization of peripheral blood hematopoietic stem cell by combining docetaxel with G-CSF was effective and safety in breast cancer patients. 展开更多
关键词 DOCETAXEL granulocyte colony-stimulating factorg-CSF) MOBILIZATION Stem cell
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Determining the sign of g factor via time-resolved Kerr rotation spectroscopy with a rotatable magnetic field
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作者 谷晓芳 钱轩 +2 位作者 姬扬 陈林 赵建华 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第8期415-418,共4页
Time-resolved Kerr rotation spectroscopy is used to determine the sign of the g factor of carriers in a semiconductor material, with the help of a rotatable magnetic field in the plane of the sample. The spin precessi... Time-resolved Kerr rotation spectroscopy is used to determine the sign of the g factor of carriers in a semiconductor material, with the help of a rotatable magnetic field in the plane of the sample. The spin precession signal of carriers at a fixed time delay is measured as a function of the orientation of the magnetic field with a fixed strength B. The signal has a sine-like form and its phase determines the sign of the g factor of carriers. As a natural extension of previous methods to measure the (time-resolved) photoluminescence or time-resolved Kerr rotation signal as a function of the magnetic field strength with a fixed orientation, such a method gives the correct sign of the g factor of electrons in GaAs. Furthermore, the sign of carriers in a (Ga, Mn)As magnetic semiconductor is also found to be negative. 展开更多
关键词 g factor time-resolved Kerr rotation gallium arsenide rotatable magnetic field
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Energy Spectrum, g Factors, Strain-Induced Level-Splittings and R-Line Thermal Shift of MgO:V^(2+)
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作者 ZHANG Zheng-Jie MA Dong-Ping 《Communications in Theoretical Physics》 SCIE CAS CSCD 2008年第8期511-516,共6页
Traditional ligand-field theory has to be improved by taking into account both pure electronic contribution and electron-phonon interaction one (including lattice-vibrational relaxation energy). By means of improved... Traditional ligand-field theory has to be improved by taking into account both pure electronic contribution and electron-phonon interaction one (including lattice-vibrational relaxation energy). By means of improved ligand-field theory, the R line, t^322T1 and t^322T2 lines, t^22(^3T1)e^4T2, t^22(^3T1)e^4T1 and t2e^2(^4A2)4T1 bands, g factors of t^32 ^4A2 and t32E, four strain-induced level-splittings and R-line thermal shift of MgO:V^2+ have been calculated. The results are in very good agreement with the experimental data. It is found that for MgO:V^2+, the contributions due to electronphonon interaction (EPI) come from the first-order term; the contributions from the second-order and higher terms are insignificant. In thermal shift of R line of MgO:V^2+, the temperature-dependent contribution due to EPI is dominant. The results obtained in this work may be used in theoretical calculations of other effects of EPI. 展开更多
关键词 improved ligand-field theory electron-phonon interaction energy spectrum strain-induced split-ting thermal shift g factor
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Theoretical Studies of Energy Spectra and g Factors of Cr3+-Doped YAl3(BO3)4
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作者 ZHANG Ji-Ping CHEN Gang ZHOU Hua-Bin 《Communications in Theoretical Physics》 SCIE CAS CSCD 2006年第6期1121-1125,共5页
With the strong-field scheme and trigonal bases, by diagonalizing the complete d^3 energy matrix in a trigonally distorted cubic-field, the energy spectra and wavefunctions of YAl3(BO3)4:Cr^3+ have been calculated... With the strong-field scheme and trigonal bases, by diagonalizing the complete d^3 energy matrix in a trigonally distorted cubic-field, the energy spectra and wavefunctions of YAl3(BO3)4:Cr^3+ have been calculated. The rates of change of levels with respect to various parameters and the contributions to levels from various parameters are calculated, and the physical origins of various levels or splittings have been clearly and quantitatively shown. By using the wavefunctions obtained from diagonalizing the complete energy matrix, the g factors of the ground state of YAl3 (BO3 )4;Cr^3+ have been evaluated. The calculated results are in good agreement with the optical-spectral and EPR experimental data. It is demonstrated that the bonding between Cr^3+ and ligands (O^2-) is ionic. 展开更多
关键词 crystal fields energy spectrum g factor electronic paramagnetic resonance
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Mononuclear cells from the cord blood and granulocytecolony stimulating factor-mobilized peripheral blood:is there a potential for treatment of cerebral palsy? 被引量:4
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作者 Hani Koh Kyoujung Hwang +2 位作者 Hae-Young Lim Yong-Joo Kim Young-Ho Lee 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第12期2018-2024,共7页
To investigate a possible therapeutic mechanism of cell therapy in the field of cerebral palsy using granulocyte-colony stimulating factor(G-CSF)-mobilized peripheral blood mononuclear cells(m PBMCs),we compared t... To investigate a possible therapeutic mechanism of cell therapy in the field of cerebral palsy using granulocyte-colony stimulating factor(G-CSF)-mobilized peripheral blood mononuclear cells(m PBMCs),we compared the expression of inflammatory cytokines and neurotrophic factors in PBMCs and m PBMCs from children with cerebral palsy to those from healthy adult donors and to cord blood mononuclear cells donated from healthy newborns.No significant differences in expression of neurotrophic factors were found between PBMCs and m PBMCs.However,in cerebral palsy children,the expression of interleukin-6 was significantly increased in m PBMCs as compared to PBMCs,and the expression of interleukin-3 was significantly decreased in m PBMCs as compared to PBMCs.In healthy adults,the expression levels of both interleukin-1βand interleukin-6 were significantly increased in m PBMCs as compared to PBMCs.The expression of brain-derived neurotrophic factors in m PBMC from cerebral palsy children was significantly higher than that in the cord blood or m PBMCs from healthy adults.The expression of G-CSF in m PBMCs from cerebral palsy children was comparable to that in the cord blood but significantly higher than that in m PBMCs from healthy adults.Lower expression of pro-inflammatory cytokines(interleukin-1β,interleukin-3,and-6)and higher expression of anti-inflammatory cytokines(interleukin-8 and interleukin-9)were observed from the cord blood and m PBMCs from cerebral palsy children rather than from healthy adults.These findings indicate that m PBMCs from cerebral palsy and cord blood mononuclear cells from healthy newborns have the potential to become seed cells for treatment of cerebral palsy. 展开更多
关键词 neurotrophic factors inflammatory cytokines cord blood g-CSF mobilized peripheralblood mononuclear cell cerebral palsy CHILDREN neural regeneration
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Granulocyte Colony-Stimulating Factor Enhances the Anticancer Effects of Cisplatin against Lung Cancer by Promoting Angiogenesis
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作者 Yun-Mo Li Yasushi Ohno +9 位作者 Norihiko Funaguchi Takenobu Gomyo Yuka Sasaki Sayaka Toyoshi Daizo Kaito Komei Yanase Junki Endo Fumitaka Ito Masanori Kawasaki Shinya Minatoguchi 《Advances in Lung Cancer》 2017年第1期1-11,共11页
The G-CSF is used as a therapeutic drug of the febrile neutropenia in lung cancer chemotherapy, however, there were few reports that showed the effects of combination effects of G-CSF and anticancer drugs against lung... The G-CSF is used as a therapeutic drug of the febrile neutropenia in lung cancer chemotherapy, however, there were few reports that showed the effects of combination effects of G-CSF and anticancer drugs against lung cancer. In the present study, we investigated the effects of G-CSF and the combination effects of G-CSF and cisplatin on lung cancer growth. We investigated the effect of G-CSF against the LL-2 and KLN-205 cells by MTT assay and tried to detect the G-CSF receptor by RT-PCR. Next, to analyze the G-CSF effects in vivo, we transplanted the LL-2 into C57BL/6 mice, intraperitoneally administered G-CSF (30 micro/kg/day) with or without cisplatin (5 mg/kg), measured the tumor size and analyzed pathologically by HE and immunostaining. In vitro analyses, G-CSF showed no effects in LL-2 and KLN-205 cells, and RT-PCR revealed no G-CSF receptor mRNA. In vivo analyses, G-CSF alone did not significantly suppress tumor growth. However, concurrent G-CSF administration with cisplatin significantly enhanced the tumor suppressing effect of cisplatin in early stage of tumor growth. The analysis data of vWF immunostaining indicated that the neovascularization in the peripheral region of the tumors was more enhanced in G-CSF treatment mice. ELISA assay revealed that G-CSF did not influence the serum concentration of TNF-alpha and IL-12 in tumor-bearing mice. This study suggests that concurrent (combination) administration of cisplatin with G-CSF is a safe and effective method for enhancing anticancer effects and reducing chemotherapeutic agent-induced myelosuppression. 展开更多
关键词 gRANULOCYTE Colony-Stimulating factor Lung Cancer g-CSF Receptor ANgIOgENESIS ANTICANCER Agent CISPLATIN TNF-ALPHA IL-12
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Electron G-Factor Anomaly and the Charge Thickness
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作者 Arlen Young 《Journal of Modern Physics》 2024年第4期435-447,共13页
The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, ref... The electron g-factor relates the magnetic moment to the spin angular momentum. It was originally theoretically calculated to have a value of exactly 2. Experiments yielded a value of 2 plus a very small fraction, referred to as the g-factor anomaly. This anomaly has been calculated theoretically as a power series of the fine structure constant. This document shows that the anomaly is the result of the electron charge thickness. If the thickness were to be zero, g = 2 exactly, and there would be no anomaly. As the thickness increases, the anomaly increases. An equation relating the g-factor and the surface charge thickness is presented. The thickness is calculated to be 0.23% of the electron radius. The cause of the anomaly is very clear, but why is the charge thickness greater than zero? Using the model of the interior structure of the electron previously proposed by the author, it is shown that the non-zero thickness, and thus the g-factor anomaly, are due to the proposed positive charge at the electron center and compressibility of the electron material. The author’s previous publication proposes a theory for splitting the electron into three equal charges when subjected to a strong external magnetic field. That theory is revised in this document, and the result is an error reduced to 0.4% in the polar angle where the splits occur and a reduced magnetic field required to cause the splits. 展开更多
关键词 Electron g-factor Anomaly Electron Charge Thickness Electron Positive Charge Electron Mass Thickness Electron Fractionalization Splitting the Electron Electron Compressibility factor
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外周血AGGF1与冠状动脉狭窄的关系
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作者 刘军锋 贾克刚 +6 位作者 车安琪 敬锐 李永姝 韩雪晶 石萍 吴萌 林文华 《检验医学》 CAS 2024年第5期423-428,共6页
目的探讨G补缀FHA域血管生成因子1(AGGF1)与冠状动脉狭窄的关系。方法选取2011年6月—2015年11月中国医学科学院北京协和医学院泰达国际心血管病医院冠状动脉狭窄患者116例。根据冠状动脉造影检查的结果,将116例患者分为病例组(狭窄>... 目的探讨G补缀FHA域血管生成因子1(AGGF1)与冠状动脉狭窄的关系。方法选取2011年6月—2015年11月中国医学科学院北京协和医学院泰达国际心血管病医院冠状动脉狭窄患者116例。根据冠状动脉造影检查的结果,将116例患者分为病例组(狭窄>50%,82例)和对照组(狭窄≤50%,34例)。采用非条件多因素逐步Logistic回归分析、受试者工作特征(ROC)曲线分别评价冠状动脉狭窄>50%的危险因素和AGGF1联合高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)对冠状动脉狭窄的诊断效能。对34例对照患者进行随访,评价AGGF1对发生主要不良心血管事件(MACE)的预测价值。结果病例组AGGF1水平显著低于对照组(P<0.001)。AGGF1下降是发生冠状动脉狭窄>50%的危险因素[比值比(OR)值为0.536,95%可信区间(CI)为0.368~0.782]。AGGF1联合HDL-C、LDL-C诊断冠状动脉狭窄的曲线下面积(AUC)为0.815。对照组随访期间高AGGF1患者无MACE发生,低AGGF1患者有6例发生MACE。结论外周血AGGF1下降是冠状动脉狭窄>50%的危险因素,AGGF1联合HDL-C、LDL-C对冠状动脉狭窄具有较高的诊断效能,AGGF1降低对冠状动脉狭窄≤50%远期发生MACE或有一定的预测价值。 展开更多
关键词 g补缀FHA域血管生成因子1 冠状动脉狭窄 冠状动脉造影检查
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Effect of the Density of Molten Metal on the Raining Phenomenon in Horizontal Centrifugal Casting
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作者 Miguel A. Barron Joan Reyes 《Open Journal of Applied Sciences》 2024年第7期1918-1926,共9页
In this work the influence of the density of the molten metal on the emergence of the raining phenomenon in the horizontal centrifugal casting process is numerically studied. Transient 2D numerical simulations were ca... In this work the influence of the density of the molten metal on the emergence of the raining phenomenon in the horizontal centrifugal casting process is numerically studied. Transient 2D numerical simulations were carried out using Computational Fluid Dynamics software. Three molten metals with different density, namely aluminum, iron and lead, and three angular frequencies, namely 50, 66 and 77 rad/s were considered. It is found that the density of the molten metal significantly affects the emergence, transient or permanent, of the rain phenomenon. However, the magnitude and duration of the rain phenomenon depend on the angular frequency of the rotating mold. Likewise, since gravitational forces affect the metal according to its density, the value of the critical rotation speed of the mold is also affected. 展开更多
关键词 Angular Frequency Centrifugal Force Computational Fluid Dynamics Critical Rotation Speed g factor Horizontal Centrifugal Casting Molten Metal Density
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少电子离子束缚态电子g因子精密测量
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作者 屠秉晟 《物理学报》 SCIE EI CAS CSCD 北大核心 2024年第20期36-46,共11页
少电子离子束缚态电子g因子的精密测量是借助原子分子体系研究束缚态量子电动力学(QED)理论的有效途径.特别是在高电荷态重核体系中,原子核与内壳层电子之间极强的电磁相互作用为研究极端电磁场环境下的QED效应提供了独一无二的条件.通... 少电子离子束缚态电子g因子的精密测量是借助原子分子体系研究束缚态量子电动力学(QED)理论的有效途径.特别是在高电荷态重核体系中,原子核与内壳层电子之间极强的电磁相互作用为研究极端电磁场环境下的QED效应提供了独一无二的条件.通过精确测量束缚态电子g因子,还可以分析核效应、测定核结构参数、确定基本物理常数等.少电子离子束缚态电子g因子的研究已经成为精密谱学方向的前沿课题.潘宁离子阱(借助稳态电磁场囚禁离子的系统)是进行g因子测量的有效实验装置之一.本综述将对基于潘宁离子阱开展少电子离子束缚态电子g因子的实验研究进行全面回顾,介绍基本实验原理与测量方法,重点论述该领域在近几年中的重要实验成果,并对未来发展进行简要展望. 展开更多
关键词 少电子离子 g因子 潘宁阱 精密测量
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MFG-E8和GNA14在子宫内膜异位症相关性卵巢癌中的表达及其临床意义
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作者 程燕 张宁 +5 位作者 董黎 凌箫鸣 王悦 陈贵芹 靖爽 陈雁南 《检验医学》 CAS 2024年第6期530-535,共6页
目的探讨乳脂球表皮生长因子8(MFG-E8)和G蛋白亚基α-14(GNA14)在子宫内膜异位症相关性卵巢癌(EAOC)中的表达及其临床意义。方法选取2015年5月—2017年5月华北医疗健康集团峰峰总医院EAOC患者51例(EAOC组)、非典型子宫内膜异位症(AEM)患... 目的探讨乳脂球表皮生长因子8(MFG-E8)和G蛋白亚基α-14(GNA14)在子宫内膜异位症相关性卵巢癌(EAOC)中的表达及其临床意义。方法选取2015年5月—2017年5月华北医疗健康集团峰峰总医院EAOC患者51例(EAOC组)、非典型子宫内膜异位症(AEM)患者63例(AEM组)、卵巢型子宫内膜异位症(EMT)患者82例(EMT组)。收集所有患者的临床资料,并检测病变组织中MFG-E8、GNA14表达。对EAOC患者随访5年。采用Kaplan-Meier生存曲线分析EAOC患者的生存情况。采用多因素Cox回归分析评估EAOC患者死亡的危险因素。结果EAOC组MFG-E8阳性率为82.35%、GNA14阳性率为70.59%,均显著高于AEM组(41.27%、44.44%)和EMT组(25.61%、23.17%)(P<0.001)。MFG-E8高表达组和低表达组肿瘤直径、肿瘤级别、国际妇产科联合会(FIGO)分期、淋巴转移情况差异均有统计学意义(P<0.05)。GNA14高表达组和低表达组淋巴转移情况差异有统计学意义(P=0.009)。Kaplan-Meier生存曲线分析结果显示,MFG-E8高表达组和GNA14高表达组无进展生存期分别短于MFG-E8低表达组和GNA14低表达组(P<0.05)。多因素Cox回归分析结果显示,FIGO分期Ⅱ期、淋巴转移、MFG-E8高表达、GNA14高表达是EAOC患者死亡的独立危险因素[风险比(HR)值分别为2.337、2.519、3.133、3.080,95%可信区间(CI)分别为1.258~4.342、1.332~4.764、1.381~7.108、1.318~7.197,P<0.01]。结论MFG-E8、GNA14在EAOC患者癌组织中呈高表达,且与患者预后不良密切相关,或可作为EAOC患者的预后评估指标。 展开更多
关键词 乳脂球表皮生长因子8 g蛋白亚基α-14 子宫内膜异位症 卵巢癌
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先兆流产患者保胎结局影响因素及与血清sHLA-G、ACA水平关系
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作者 凌艳娟 王芳 +1 位作者 涂春燕 邹婷 《中国计划生育学杂志》 2024年第8期1883-1887,共5页
目的:探索先兆流产患者保胎结局的影响因素,并分析其与血清可溶性人白细胞抗原-G(sHLA-G)、抗心磷脂抗体(ACA)的关系。方法:回顾性收集2021年6月-2023年6月本院收治的80例先兆流产患者临床资料,根据保胎结局分为保胎失败组与保胎成功组... 目的:探索先兆流产患者保胎结局的影响因素,并分析其与血清可溶性人白细胞抗原-G(sHLA-G)、抗心磷脂抗体(ACA)的关系。方法:回顾性收集2021年6月-2023年6月本院收治的80例先兆流产患者临床资料,根据保胎结局分为保胎失败组与保胎成功组,对比两组一般资料,酶联免疫吸附法检测两组sHLA-G、ACA水平,经单因素及Pearson相关性分析法探讨先兆流产保胎结局的影响因素及与血清sHLA-G、ACA水平关系。结果:两组年龄、既往流产史、合并阴道炎、生殖道感染、妊娠期糖尿病、接触有毒化学物质等方面有差异;保胎失败组sHLA-G(7.43±1.20 U/ml)水平低于保胎成功组(50.14±4.56 U/ml),ACA阳性率(74.1%)高于保胎成功组(20.8%)(均P<0.05)。logistic回归分析,高龄、既往流产史、合并阴道炎、生殖道感染、妊娠期糖尿病、接触有毒化学物质、sHLA-G水平低、ACA阳性率高均是影响先兆流产患者保胎结局的重要因素;Pearson相关性分析,年龄、既往流产史、合并阴道炎、生殖道感染、妊娠期糖尿病、接触有毒化学物质与血清sHLA-G水平呈负相关,与ACA阳性率呈正相关(均P<0.05)。结论:先兆流产患者保胎结局可能与高龄、既往流产史、合并阴道炎、生殖道感染、妊娠期糖尿病、接触有毒化学物质、sHLA-G水平及ACA阳性率有关,临床可针对上述因素给予密切关注,并通过监测sHLA-G水平及ACA阳性率的变化来指导临床早期干预,以确保母婴安全。 展开更多
关键词 先兆流产 保胎结局 血清可溶性人白细胞抗原-g 抗心磷脂抗体 影响因素
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Features of Recombination Radiation of GaAs Type Semiconductors with the Participation of Fine Acceptor Levels in a Magnetic Field
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作者 Nosirjon Khaydarovich Yuldashev Iftixorjon Isaqovich Yulchiev +1 位作者 Bozorboy Joboraliyevich Akhmadaliev Khusanboy Manopovich Sulaymonov 《Journal of Applied Mathematics and Physics》 2024年第7期2407-2420,共14页
Using the method of Picus and Beer invariants, general expressions are obtained for the total intensity I and the degree of circular polarization Рcirc.of the luminescence of GaAs-type semiconductors with the partici... Using the method of Picus and Beer invariants, general expressions are obtained for the total intensity I and the degree of circular polarization Рcirc.of the luminescence of GaAs-type semiconductors with the participation of shallow acceptor levels in a longitudinal magnetic field H. Special cases are analyzed depending on the value and direction of the magnetic field strength, as well as on the constants of the g-factor of the acceptor g1,g2and the conduction band electron ge. In the case of a strong magnetic field H// [100], [111], [110], a numerical calculation of the angular dependence of the quantities I and Рcirc.was performed for some critical values of g2/g1, at which Рcirc.exhibits a sharp anisotropy in the range from −100% to +100%, and the intensity of the crystal radiation along the magnetic field tends to a minimum value. 展开更多
关键词 Semiconductor Recombination Radiation Shallow Acceptor Center Magnetic Field Zeeman Splitting g-factorS Anisotropy Circular Polarization Intensity
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GPER抑制星形胶质细胞活性减少OIR小鼠视网膜新生血管生成的机制研究
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作者 王璇 叶剑 刘玮 《陆军军医大学学报》 CAS CSCD 北大核心 2024年第12期1369-1377,共9页
目的探究在氧诱导下的新生小鼠视网膜缺血模型(oxygen-induced retinopathy,OIR)中,G蛋白偶联雌激素受体(G proteincoupled estrogen receptor,GPER)减少OIR小鼠视网膜新生血管生成的机制。方法42只新生小鼠采用随机数字表法分为4组:常... 目的探究在氧诱导下的新生小鼠视网膜缺血模型(oxygen-induced retinopathy,OIR)中,G蛋白偶联雌激素受体(G proteincoupled estrogen receptor,GPER)减少OIR小鼠视网膜新生血管生成的机制。方法42只新生小鼠采用随机数字表法分为4组:常氧对照组(n=11)、OIR组(n=11)、G-1(GPER激动剂)组(n=10)和溶剂对照组(n=10)。出生后17 d(P17)时,眼球冰冻切片免疫荧光染色观察常氧对照组小鼠GPER在视网膜分布情况。G-1组和溶剂对照组在P12~P15时分别腹腔注射给予G-1[50μg/(kg·d)]或玉米油溶剂,P17时视网膜铺片免疫荧光染色观察视网膜血管标志物(IB4)、星形胶质细胞标志物胶质纤维酸性蛋白(glia fibrilary acidic protein,GFAP)表达,蛋白免疫印迹法定量检测视网膜血管内皮生长因子A(vascular endothelial growth factor A,VEGFA)、GFAP、炎症因子TNF-α、IGF-1、IL1-β蛋白表达情况。结果GPER存在于小鼠视网膜全层,在视网膜神经节细胞层与星形胶质细胞标志物GFAP共染。与常氧对照组相比,OIR组小鼠视网膜出现新生血管与无血管区,且GPER、VEGFA和GFAP表达增多,差异具有统计学意义(P<0.05);与溶剂对照组相比,G-1组视网膜新生血管生成减少,VEGFA、GFAP、TNF-α、IGF-1、IL1-β蛋白表达下降,差异具有统计学意义(P<0.05)。结论GPER能抑制星形胶质细胞活性,减少VEGFA、炎症因子释放,减少OIR小鼠视网膜新生血管生成。 展开更多
关键词 早产儿视网膜病变 氧诱导下的新生小鼠视网膜缺血模型 星形胶质细胞 炎症因子 g蛋白偶联雌激素受体
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致密碳酸盐岩气藏裂缝预测及主控因素分析——以四川盆地G气田震旦系灯影组为例
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作者 周永胜 吴伟 +2 位作者 冯建伟 刘水珍 王光绪 《东北石油大学学报》 CAS 北大核心 2024年第2期102-115,I0007,I0008,共16页
四川盆地G气田致密碳酸盐岩储层裂缝发育控制因素认识不清。考虑岩性弹脆性差异,分析岩心单井裂缝发育特征和裂缝形成期次,进行应力场数值模拟,建立应力场—能量—裂缝参数计算模型;结合多期裂缝叠加算法,预测G气田灯影组储层裂缝,分析... 四川盆地G气田致密碳酸盐岩储层裂缝发育控制因素认识不清。考虑岩性弹脆性差异,分析岩心单井裂缝发育特征和裂缝形成期次,进行应力场数值模拟,建立应力场—能量—裂缝参数计算模型;结合多期裂缝叠加算法,预测G气田灯影组储层裂缝,分析裂缝发育主控因素。结果表明:G气田灯影组储层裂缝具有多期性与多样性,以高角度、半充填张剪缝为主。研究区中部褶皱顶部及断层影响区是碳酸盐岩裂缝优势发育带,裂缝密度为1.10~2.30条/m,开度大于1.5 mm;泥岩裂缝发育程度弱,裂缝密度低于0.50条/m,开度小于0.4 mm,泥岩隔层裂缝发育总体低于碳酸盐岩层的,且规律性差。裂缝发育符合断层—褶皱—裂缝共生模式。岩性、断层与构造形态共同控制碳酸盐岩储层裂缝发育规模与分布范围。该结果有助于提高同类型致密碳酸盐岩储层裂缝预测效果,改进油气藏开发方案。 展开更多
关键词 致密碳酸盐岩 裂缝预测 主控因素 应力场模拟 灯影组 g气田 四川盆地
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肝癌组织中GPSM2、TGF-β1蛋白表达水平及临床意义 被引量:1
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作者 霍亮 骆杨 冯海林 《实用癌症杂志》 2024年第3期406-410,共5页
目的 探讨肝癌组织G蛋白信号调节蛋白(GPSM)2、转化生长因子1(TGF-β1)蛋白表达与临床病理参数及预后的关系。方法 选取原发性肝癌患者80例,取手术切除的肝癌组织和癌旁正常组织。采用免疫组织化学染色法检测GPSM2、TGF-β1在癌组织和... 目的 探讨肝癌组织G蛋白信号调节蛋白(GPSM)2、转化生长因子1(TGF-β1)蛋白表达与临床病理参数及预后的关系。方法 选取原发性肝癌患者80例,取手术切除的肝癌组织和癌旁正常组织。采用免疫组织化学染色法检测GPSM2、TGF-β1在癌组织和癌旁正常组织中的表达差异,分析癌组织中GPSM2、TGF-β1表达水平与临床病理参数及预后的关系。结果 肝癌组织中GPSM2、TGF-β1高表达率分别为71.25%、82.50%,高于癌旁正常组织的18.75%、13.75%(P<0.05)。GPSM2在分化程度低的肝癌组织中高表达率较高(P<0.05),TGF-β1在分化程度低、有血管转移的肝癌组织中高表达率较高(P<0.05)。生存曲线显示,GPSM2、TGF-β1低表达患者的累积生存率(77.27%、85.71%)高于高表达患者(47.37%、48.48%),差异具有统计学意义(P<0.05)。结论 GPSM2、TGF-β1在肝癌组织中高表达率较高,其表达水平与分化程度密切相关,GPSM2、TGF-β1高表达患者预后较差。 展开更多
关键词 原发性肝癌 g蛋白信号调节蛋白2 转化生长因子1 临床病理参数 预后
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血清抗环瓜氨酸肽抗体、类风湿因子、免疫球蛋白G、补体C3、补体C4检测在类风湿关节炎诊断中的应用价值
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作者 付鹏 张敏 《中国社区医师》 2024年第7期80-82,共3页
目的:探讨血清抗环瓜氨酸肽(CCP)抗体、类风湿因子(RF)、免疫球蛋白G(IgG)、补体C3、补体C4检测在类风湿关节炎诊断中的应用价值。方法:选取2020年3月—2022年3月枝江市人民医院收治的类风湿关节炎患者126例作为观察组,另选取同期体检... 目的:探讨血清抗环瓜氨酸肽(CCP)抗体、类风湿因子(RF)、免疫球蛋白G(IgG)、补体C3、补体C4检测在类风湿关节炎诊断中的应用价值。方法:选取2020年3月—2022年3月枝江市人民医院收治的类风湿关节炎患者126例作为观察组,另选取同期体检健康者126例作为对照组,根据类风湿关节炎疾病活动(DAS-28)评分将观察组分为缓解期组(n=72)与活动期组(n=54)。所有研究对象检测血清CCP抗体、RF、IgG、补体C3、补体C4水平。比较各组各项指标水平。结果:观察组血清CCP抗体、RF、IgG、补体C3、补体C4水平均高于对照组,差异有统计学意义(P<0.001)。活动期组血清CCP抗体、RF、IgG、补体C3、补体C4水平均高于缓解期组,差异有统计学意义(P<0.001)。结论:类风湿关节炎患者体内血清CCP抗体、RF、IgG、补体C3、补体C4均异常升高,并与类风湿关节炎病情活动度有关,可作为类风湿关节炎早期诊断及病情监测的重要指标。 展开更多
关键词 类风湿关节炎 补体C3 补体C4 类风湿因子 抗环瓜氨酸肽抗体 免疫球蛋白g
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g factors of nuclear low-lying states:A covariant description 被引量:5
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作者 YAO JiangMing PENG Jing +1 位作者 MENG Jie RING Peter 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2011年第2期198-203,共6页
The g factors and spectroscopic quadrupole moments of low-lying excited states 2+1,…,81+ in 24Mg are studied in a covariant density functional theory.The wave functions are constructed by configuration mixing of axia... The g factors and spectroscopic quadrupole moments of low-lying excited states 2+1,…,81+ in 24Mg are studied in a covariant density functional theory.The wave functions are constructed by configuration mixing of axially deformed mean-field states projected on good angular momentum.The mean-field states are obtained from the constraint relativistic point-coupling model plus BCS calculations using the PC-F1 parametrization for the particle-hole channel and a density-independent delta-force for the particle-particle channel.The available experimental g factor and spectroscopic quadrupole moment of 21+ state are reproduced quite well.The angular momentum dependence of g factors and spectroscopic quadrupole moments,as well as the effects of pairing correlations are investigated. 展开更多
关键词 covariant density functional theory magnetic moment g factor spectroscopic quadrupole moment
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