AIM: Consecutive monitoring of intragastric pH using the Bravo? capsule. METHODS: We put threads through a Bravo? capsule and then affixed it to the gastric wall by endoscopic hemoclipping in seven subjects. Study dat...AIM: Consecutive monitoring of intragastric pH using the Bravo? capsule. METHODS: We put threads through a Bravo? capsule and then affixed it to the gastric wall by endoscopic hemoclipping in seven subjects. Study data were uploaded to a computer via Datalink every 48 h. In this way,repeated monitoring of intragastric pH was undertaken. RESULTS: All subjects were able to monitor gastric pH over a 1-wk period,and five for > 2 wk. No complications were encountered during the monitoring. After pH monitoring,we safely retrieved the capsule endoscopically. CONCLUSION: Clipping a Bravo? capsule onto the gastric wall enabled long-term intragastric pH monitoring. This is a methodological report of pH monitoring over a period of > 2 wk.展开更多
Objective To investigate the changes of perioperative serum levels of interleukin-6(IL-6), C-reactive protein (CRP), and cortisol, as well as gastric intramucosal pH (pHi) and plasma lactate, aiming to compare systemi...Objective To investigate the changes of perioperative serum levels of interleukin-6(IL-6), C-reactive protein (CRP), and cortisol, as well as gastric intramucosal pH (pHi) and plasma lactate, aiming to compare systemic changes and tissue perfusion during colorectal and orthopaedic surgical procedures. Methods Twenty patients were randomly assigned to two groups, 10 cases of operation on vertebral canal, 10 cases of colorectal radical operation.Venous blood was drawn at 1 day before operation, 2, 4, and 6 hours following skin incision, and 1 day after operation, in order to measure serum IL-6, CRP, and cortisol.pHi and plasma lactate were also measured at the same time points.Results Serum concentrations of IL-6 and cortisol increased gradually following operation, reaching the peak value at 6 hours from the beginning of operation.CRP was not detectable until the first day after operation.Peak concentration of IL-6 had positive relationship with CRP.These variables changed more significantly in colorectal group than that in orthopaedic group (P<0.05).pHi decreased gradually, reaching the lowest level at 4 hours from the beginning of operation, and to more extent in colorectal group than that in orthopaedic group (P<0.05).Conclusion IL-6 may reflect tissue damage more sensitively than CRP.Colorectal surgery might induce systemic disorder to more extent, in terms of immuno-endocrinal aspect as well as tissue perfusion, reflected with pHi.展开更多
In this research, the state of the gastric secretion in 38 days old ostrich embryos and chicks of different age was investigated by determining the pH level in the stomach as well as the histological structure of the ...In this research, the state of the gastric secretion in 38 days old ostrich embryos and chicks of different age was investigated by determining the pH level in the stomach as well as the histological structure of the deep proventricular glands （gll. proventriculares profundi）. In both parts of the stomach, on the 38th day of embryonic development pH parameters were higher than in chicks after hatching. The proventricular deep gland lobules and secretory epithelium on the 38th day of embryonic development and on the day of hatching were comparatively poorly developed. The most rapid increase of the proportion of the secretory epithelium of the proventricular deep glands was observed just before hatching and during the first week after hatching, but having reached two weeks of age it did not increase any more. The obtained results allow making a conclusion that already on the day of hatching an intensive gastric juice secretion occurs in the proventricular deep glands regardless of the stage of their histological development. The gastric intraluminal pH parameters indicate that the gastric secretion increases with chicks advancing in age, however on the day of hatching this important gastric function is biologically rather complete.展开更多
目的探讨后腹腔镜手术中二氧化碳(CO2)气腹对全麻患者胃粘膜pH(i-pH)和胃粘膜-动脉CO2分压差(Pg-aCO2)的影响。方法选择后腹腔镜下行肾及肾上腺手术患者20例,监测气腹前、气腹后30、60 min以及放气后30 min患者i-pH和Pg-aCO2的变化。结...目的探讨后腹腔镜手术中二氧化碳(CO2)气腹对全麻患者胃粘膜pH(i-pH)和胃粘膜-动脉CO2分压差(Pg-aCO2)的影响。方法选择后腹腔镜下行肾及肾上腺手术患者20例,监测气腹前、气腹后30、60 min以及放气后30 min患者i-pH和Pg-aCO2的变化。结果气腹后动脉血CO2分压(PaCO2)较气腹前明显增加,pH值明显下降(P<0.05)。气腹后306、0 min i-pH较气腹前显著降低,而Pg-aCO2显著增加(P<0.01)。放气30 min i-pH虽较气腹期间有所回升,但与气腹前比较仍有显著性差异(P<0.05)。结论后腹腔镜CO2气腹可引起高碳酸血症和胃粘膜血流灌注降低。展开更多
文摘AIM: Consecutive monitoring of intragastric pH using the Bravo? capsule. METHODS: We put threads through a Bravo? capsule and then affixed it to the gastric wall by endoscopic hemoclipping in seven subjects. Study data were uploaded to a computer via Datalink every 48 h. In this way,repeated monitoring of intragastric pH was undertaken. RESULTS: All subjects were able to monitor gastric pH over a 1-wk period,and five for > 2 wk. No complications were encountered during the monitoring. After pH monitoring,we safely retrieved the capsule endoscopically. CONCLUSION: Clipping a Bravo? capsule onto the gastric wall enabled long-term intragastric pH monitoring. This is a methodological report of pH monitoring over a period of > 2 wk.
文摘Objective To investigate the changes of perioperative serum levels of interleukin-6(IL-6), C-reactive protein (CRP), and cortisol, as well as gastric intramucosal pH (pHi) and plasma lactate, aiming to compare systemic changes and tissue perfusion during colorectal and orthopaedic surgical procedures. Methods Twenty patients were randomly assigned to two groups, 10 cases of operation on vertebral canal, 10 cases of colorectal radical operation.Venous blood was drawn at 1 day before operation, 2, 4, and 6 hours following skin incision, and 1 day after operation, in order to measure serum IL-6, CRP, and cortisol.pHi and plasma lactate were also measured at the same time points.Results Serum concentrations of IL-6 and cortisol increased gradually following operation, reaching the peak value at 6 hours from the beginning of operation.CRP was not detectable until the first day after operation.Peak concentration of IL-6 had positive relationship with CRP.These variables changed more significantly in colorectal group than that in orthopaedic group (P<0.05).pHi decreased gradually, reaching the lowest level at 4 hours from the beginning of operation, and to more extent in colorectal group than that in orthopaedic group (P<0.05).Conclusion IL-6 may reflect tissue damage more sensitively than CRP.Colorectal surgery might induce systemic disorder to more extent, in terms of immuno-endocrinal aspect as well as tissue perfusion, reflected with pHi.
文摘In this research, the state of the gastric secretion in 38 days old ostrich embryos and chicks of different age was investigated by determining the pH level in the stomach as well as the histological structure of the deep proventricular glands （gll. proventriculares profundi）. In both parts of the stomach, on the 38th day of embryonic development pH parameters were higher than in chicks after hatching. The proventricular deep gland lobules and secretory epithelium on the 38th day of embryonic development and on the day of hatching were comparatively poorly developed. The most rapid increase of the proportion of the secretory epithelium of the proventricular deep glands was observed just before hatching and during the first week after hatching, but having reached two weeks of age it did not increase any more. The obtained results allow making a conclusion that already on the day of hatching an intensive gastric juice secretion occurs in the proventricular deep glands regardless of the stage of their histological development. The gastric intraluminal pH parameters indicate that the gastric secretion increases with chicks advancing in age, however on the day of hatching this important gastric function is biologically rather complete.
文摘目的探讨后腹腔镜手术中二氧化碳(CO2)气腹对全麻患者胃粘膜pH(i-pH)和胃粘膜-动脉CO2分压差(Pg-aCO2)的影响。方法选择后腹腔镜下行肾及肾上腺手术患者20例,监测气腹前、气腹后30、60 min以及放气后30 min患者i-pH和Pg-aCO2的变化。结果气腹后动脉血CO2分压(PaCO2)较气腹前明显增加,pH值明显下降(P<0.05)。气腹后306、0 min i-pH较气腹前显著降低,而Pg-aCO2显著增加(P<0.01)。放气30 min i-pH虽较气腹期间有所回升,但与气腹前比较仍有显著性差异(P<0.05)。结论后腹腔镜CO2气腹可引起高碳酸血症和胃粘膜血流灌注降低。
