Membrane separation technology with the ability to regulate gas/liquid transport and separation is critical for environmental fields, such as sewerage treatment, multiphase separation, and desalination. Although numer...Membrane separation technology with the ability to regulate gas/liquid transport and separation is critical for environmental fields, such as sewerage treatment, multiphase separation, and desalination. Although numerous membranes can dynamically control liquid-phase fluids transport via external stimuli, the transport and separation of gas-phase fluids remains a challenge. Here, we show a temperature-regulation liquid gating membrane that allows in-situ dynamically controllable gas/liquid transfer and multiphase separation by integrating a thermo-wettability responsive porous membrane with functional gating liquid. Experiments and theoretical analysis have demonstrated the temperature-regulation mechanism of this liquid gating system, which is based on thermo-responsive changes of porous membrane surface polarity, leading to changes in affinity between the porous membrane and the gating liquid. In addition, the sandwich configuration with dense Au-coated surfaces and heterogeneous internal components by a bistable interface design enables the liquid gating system to enhance response sensitivity and maintain working stability. This temperature-regulation gas/liquid transfer strategy expands the application range of liquid gating membranes,which are promising in environmental governance, water treatment and multiphase separation.展开更多
The self-absorption effect in laser-induced breakdown spectroscopy(LIBS)reduces the accuracy of quantitative measurement results.The self-absorption-free LIBS(SAF-LIBS)has been proved to directly capture the optically...The self-absorption effect in laser-induced breakdown spectroscopy(LIBS)reduces the accuracy of quantitative measurement results.The self-absorption-free LIBS(SAF-LIBS)has been proved to directly capture the optically thin plasma spectra by setting an appropriate exposure time.In this work,a novel SAF-LIBS technique with high repetition rate acousto-optic gating is developed,in which an acousto-optic modulator is used as the shutter to diffract the optically thin fluorescence,and a high repetition rate laser is used to produce quasi-continuous plasmas to enhance the integral spectral intensity,so that the CCD spectrometer can replace an intensified CCD(ICCD)and echelle spectrometer in SAF-LIBS.Experimental results show that the average absolute prediction error of aluminum is reduced to 0.18%,which is equivalent to that of traditional SAF-LIBS.This technique not only effectively shields continuous background radiation and broadened spectral lines in optically thick plasma,but also has advantages of miniaturization,low cost,convenience and reliability.展开更多
High pressure die casting(HPDC) is a kind of near net shape manufacturing method. However, air entrapment in HPDC parts has serious effects upon the casting quality. In order to reduce the air entrapment defects in a ...High pressure die casting(HPDC) is a kind of near net shape manufacturing method. However, air entrapment in HPDC parts has serious effects upon the casting quality. In order to reduce the air entrapment defects in a AlSi10 MnMg alloy thin-wall longitudinal load-bearing beam produced by HPDC, different gating systems were designed and simulated by software Flow-3D to evaluate the entrapped air. Simulation results showed that when the beam is produced by the original designed gating system with a middle ingate, there exist obvious air entrapments in the critical area; the volume of air entrapment was reduced by replacing the middle ingate to an overflow well, and the filling of molten metal became more stable. When the middle ingate was removed for further improvement, the volume of air entrapment was decreased drastically. The parts with glossy surface and good microstructure have been successfully produced by using the final optimized gating system based on simulation results.展开更多
We report protonation in several compounds by an ionic-liquid-gating method, under optimized gating conditions.This leads to single superconducting phases for several compounds. Non-volatility of protons allows post-g...We report protonation in several compounds by an ionic-liquid-gating method, under optimized gating conditions.This leads to single superconducting phases for several compounds. Non-volatility of protons allows post-gating magnetization and transport measurements. The superconducting transition temperature Tc is enhanced to 43.5 K for FeSe0.93S0.07, and 41 K for Fe Se after protonation. Superconducting transitions with Tc^15 K for ZrNCl,~7.2 K for 1-TaS2, and ~3.8 K for Bi2Se3 are induced after protonation. Electric transport in protonated FeSe0.93S0.07 confirms high-temperature superconductivity. Our ^1H nuclear magnetic resonance(NMR)measurements on protonated Fe Se1-xSx reveal enhanced spin-lattice relaxation rate 1/^1T1 with increasing x,which is consistent with the LDA calculations that H+ is located in the interstitial sites close to the anions.展开更多
The gating system of a cylindrical magnesium casting has been designed by using multiple objective optimiza- tion and Taguchi method.Mold filling and solidification processes were simulated by using MAGMASOFT(?). T...The gating system of a cylindrical magnesium casting has been designed by using multiple objective optimiza- tion and Taguchi method.Mold filling and solidification processes were simulated by using MAGMASOFT(?). The simulation results indicate that the gating system design has a significant effect on the quality of magne- sium castings.In an effort to obtain the optimal design of gating system,the signal-to-noise (S/N) ratio was used to analyze the effect of various gating designs on cavity filling and casting quality by using a weighting method based on the design of an orthogonal array.Four gating system parameters,namely,ingate height, ingate width,runner height,runner width,were optimized with a consideration of multiple objective criteria including filling velocity,shrinkage porosity and product yield.展开更多
The electronic doping effect on both the superconductivity and the nematic order in the FeSe nanoflake are investigated by using the electric-double-layer transistor configuration. The superconductivity can be effecti...The electronic doping effect on both the superconductivity and the nematic order in the FeSe nanoflake are investigated by using the electric-double-layer transistor configuration. The superconductivity can be effectively controlled by electronic doping, and the onset superconducting transition temperature Tc reaches as high as 45 K at a gate voltage Of Vg = 4 V. Meanwhile, the nematic phase is gradually suppressed with the increase of electronic doping (or Vg). The results provide an effective method with variable charge doping for investigation of the rich physics in the FeSe superconductor.展开更多
A convolutional neural network is employed to retrieve the time-domain envelop and phase of few-cycle femtosecond pulses from transient-grating frequency-resolved optical gating(TG-FROG) traces.We use theoretically ge...A convolutional neural network is employed to retrieve the time-domain envelop and phase of few-cycle femtosecond pulses from transient-grating frequency-resolved optical gating(TG-FROG) traces.We use theoretically generated TGFROG traces to complete supervised trainings of the convolutional neural networks,then use similarly generated traces not included in the training dataset to test how well the networks are trained.Accurate retrieval of such traces by the neural network is realized.In our case,we find that networks with exponential linear unit(ELU) activation function perform better than those with leaky rectified linear unit(LRELU) and scaled exponential linear unit(SELU).Finally,the issues that need to be addressed for the retrieval of experimental data by this method are discussed.展开更多
The carrier-density-dependent spin relaxation dynamics for modulation-doped GaAs/Al0.3 Gao,TAs quantum wells is studied using the time-resolved magneto-Kerr rotation measurements. The electron spin relaxation time and...The carrier-density-dependent spin relaxation dynamics for modulation-doped GaAs/Al0.3 Gao,TAs quantum wells is studied using the time-resolved magneto-Kerr rotation measurements. The electron spin relaxation time and its in-plane anisotropy are studied as a function of the optically injected electron density, Moreover, the relative strength of the Rashba and the Dresselhaus spin-rbit coupling fields, and thus the observed spin relaxation time anisotropy, is further tuned by the additional excitation of a 532nm continuous wave laser, demonstrating an effective spin relaxation manipulation via an optical gating method.展开更多
GHz single-photon detector (SPD) is a crucial part in the practical high speed quantum key distribution (QKD) system. However, any imperfections in a practical QKD system may be exploited by an eavesdropper (Eve...GHz single-photon detector (SPD) is a crucial part in the practical high speed quantum key distribution (QKD) system. However, any imperfections in a practical QKD system may be exploited by an eavesdropper (Eve) to collect information about the key without being discovered. The sine wave gating SPD (SG-SPD) based on InGaAs/InP avalanche photodiode, one kind of practical high speed SPD, may also contain loopholes. In this paper, we study the principle and characteristic of the SG-SPD and find out the filtering loophole of the SG-SPD for the first time. What is more, the proof-of-principle experiment shows that Eve could blind and control Bob's SG-SPD by exploiting this loophole. We believe that giving enough attention to this loophole can improve the practical security of the existing QKD system. GHz single-photon detector (SPD) is a crucial part in the practical high speed quantum key distribution (QKD) system. However, any imperfections in a practical QKD system may be exploited by an eavesdropper (Eve) to collect information about the key without being discovered. The sine wave gating SPD (SG-SPD) based on InGaAs/InP avalanche photodiode, one kind of practical high speed SPD, may also contain loopholes. In this paper, we study the principle and characteristic of the SG-SPD and find out the filtering loophole of the SG-SPD for the first time. What is more, the proof-of-principle experiment shows that Eve could blind and control Bob's SG-SPD by exploiting this loophole. We believe that giving enough attention to this loophole can improve the practical security of the existing QKD system.展开更多
We report the electrical transport properties of InSe flakes electrostatically gated by a solid ion conductor.The large tuning capability of the solid ion conductor as gating dielectric is confirmed by the saturation ...We report the electrical transport properties of InSe flakes electrostatically gated by a solid ion conductor.The large tuning capability of the solid ion conductor as gating dielectric is confirmed by the saturation gate voltage as low as^1 V and steep subthreshold swing(83 mV/dec).The p-type conduction behavior of InSe is obtained when negative gate voltages are biased.Chemical doping of the solid ion conductor is suppressed by inserting a buffer layer of hexagonal boron nitride(h-BN)between InSe and the solid-ion-conductor substrate.By comparing the performance of devices with and without h-BN,the capacitance of solid ion conductors is extracted to be the same as that of^2 nm h-BN,and the mobility of InSe on solid ion conductors is comparable to that on the SiO2 substrate.Our results show that solid ion conductors provide a facile and powerful method for electrostatic doping.展开更多
The classical model of voltage-gated ion channels assumes that according to a Markov process ion channels switch among a small number of states without memory, but a bunch of experimental papers show that some ion cha...The classical model of voltage-gated ion channels assumes that according to a Markov process ion channels switch among a small number of states without memory, but a bunch of experimental papers show that some ion channels exhibit significant memory effects, and this memory effects can take the form of kinetic rate constant that is fractal. Obviously the gating character of ion channels will affect generation and propagation of action potentials, furthermore, affect generation, coding and propagation of neural information. However, there is little previous research on this series of interesting issues. This paper investigates effects of fractal gating of potassium channel subunits switching from closed state to open state on neuronal behaviours. The obtained results show that fractal gating of potassium channel subunits switching from closed state to open state has important effects on neuronal behaviours, increases excitability, rest potential and spiking frequency of the neuronal membrane, and decreases threshold voltage and threshold injected current of the neuronal membrane. So fractal gating of potassium channel subunits switching from closed state to open state can improve the sensitivity of the neuronal membrane, and enlarge the encoded strength of neural information.展开更多
The delegating private quantum computation(DQC)protocol with the universal quantum gate set{X,Z,H,P,R,CNOT}was firstly proposed by Broadbent et al.[Broadbent(2015)],and then Tan et al.[Tan and Zhou(2017)]tried to put ...The delegating private quantum computation(DQC)protocol with the universal quantum gate set{X,Z,H,P,R,CNOT}was firstly proposed by Broadbent et al.[Broadbent(2015)],and then Tan et al.[Tan and Zhou(2017)]tried to put forward a half-blind DQC protocol(HDQC)with another universal set{H,P,CNOT,T}.However,the decryption circuit of Toffoli gate(i.e.T)is a little redundant,and Tan et al.’s protocol[Tan and Zhou(2017)]exists the information leak.In addition,both of these two protocols just focus on the blindness of data(i.e.the client’s input and output),but do not consider the blindness of computation(i.e.the delegated quantum operation).For solving these problems,we propose a full-blind DQC protocol(FDQC)with quantum gate set{H,P,CNOT,T},where the desirable delegated quantum operation,one of{H,P,CNOT,T},is replaced by a fixed sequence(H,P,CZ,CNOT,T)to make the computation blind,and the decryption circuit of Toffoli gate is also optimized.Analysis shows that our protocol can not only correctly perform any delegated quantum computation,but also holds the characteristics of data blindness and computation blindness.展开更多
Both polarization gating (PG) and double optical gating (DOG) are productive methods to generate single attosecond (as) pulses. In this paper, considering the ground-state depletion effect, we investigate the wa...Both polarization gating (PG) and double optical gating (DOG) are productive methods to generate single attosecond (as) pulses. In this paper, considering the ground-state depletion effect, we investigate the wavelength-dependence of the DOG method in order to optimize the generation of single attosecond pulses for the future application. By calculating the ionization probabilities of the leading edge of the pulse at different driving laser wavelengths, we obtain the upper limit of duration for the driving laser pulse for the DOG setup. We find that the upper limit duration increases with the increase of laser wavelength. We further describe the technical method of choosing and calculating the thickness values of optical components for the DOG setup.展开更多
We report a tunable transverse magnetoresistance of the planar Hall effect(PHE),up to 48%in the Ni80Fe20/HfO2 heterostructures.This control is achieved by applying a gate voltage with an ionic liquid technique at ultr...We report a tunable transverse magnetoresistance of the planar Hall effect(PHE),up to 48%in the Ni80Fe20/HfO2 heterostructures.This control is achieved by applying a gate voltage with an ionic liquid technique at ultra-low voltage,which exhibits a gate-dependent PHE.Moreover,in the range of 0-V to 1-V gate voltage,transverse magnetoresistance of PHE can be continuously regulated.Ferromagnetic resonance(FMR)also demonstrates the shift of the resonance field at low gate voltage.This provides a new method for the design of the electric field continuous control spintronics device with ultra-low energy consumption.展开更多
As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resti...As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resting membrane potential and modulate membrane excitability. It has been reported that residue E224 plays a key role in regulating inward rectification. The mutant Kir2.1 (E224G) displays weaker inward rectification than the WT channel. Gating of Kir2.1 depends on the membrane lipid, PIP<sub>2</sub>, such that the channel gates are closed in the absence of PIP<sub>2</sub>. Here we perform electrophysiological and computational approaches, and demonstrate that E224 also plays an important role in the PIP<sub>2</sub>-dependent activation of Kir2.1 in addition to its influence on inward rectification. The E224G mutant takes 4.5 times longer to be activated by PIP<sub>2</sub>. To probe the mechanism by which E224G slows the channel opening kinetics, we perform targeted molecular dynamics simulations and find that the mutant weakens the interactions between CD-loop and C-linker (H221-R189) and the adjacent G-loops (R312-E303) which are thought to stabilize the open state of the channel in our previous work. These data provide new insights into the regulation of Kir2.1 channel activity and suggest that a common mechanism may be involved in the distinct biophysical processes, such as inward rectification and PIP<sub>2</sub>-induced gating.展开更多
Mice subjected to an irregular light-dark cycle are known to lose their capacity to synchronize their behavioral rhythm to environmental light, and to show endophenotypes related to depressive disorders. Here we obser...Mice subjected to an irregular light-dark cycle are known to lose their capacity to synchronize their behavioral rhythm to environmental light, and to show endophenotypes related to depressive disorders. Here we observed that a susceptible strain of mice (C3H/HeJ) subjected to an irregular 3.5 hr:3.5 hr light-dark cycle showed an enhanced acoustic startle reflex and deficits in prepulse inhibition. As impaired sensorimotor gating is associated with the onset of a variety of mental disorders such as schizophrenia and major depressive disorder, irregular environmental light without circadian photo-entrainment may cause stress that has the potential to be involved in humans’ susceptibility to neuropsychiatric abnormalities.展开更多
Mechanosensitive(MS) ion channels play an important role in various physiological processes.Although the determination of the structure of mechanosensitive channel of large conductance(MscL) makes the simulation s...Mechanosensitive(MS) ion channels play an important role in various physiological processes.Although the determination of the structure of mechanosensitive channel of large conductance(MscL) makes the simulation study possible,it has not so far been possible to directly simulate the gating mechanism of MscL in atomic detail.In this article,MscL has been studied via molecular dynamic(MD) simulations to gain a detailed description of the sensitivity to lateral tension and the gating pathway.MscL undergoes conformational rearrangement in sustaining lateral tension,and the open state is obtained when 2.0 MPa lateral tension is directly applied on the pure protein.During the opening process,Loop region responds to tension first,and the mechanical sensitivity is followed by S1 domain.Transmembrane(TM) bundle is the key position for channel opening,and the motion of TM1 helices finally realizes the significant expansion of the constricted gating pore.C-terminus domain presents expansion later during the TM opening.In our study,return of the whole protein to the initial closed state is achieved only in the early opening stage.During the relaxation from the open state,the TM helices are the most mobile domain,which is different from the opening process.展开更多
基金supported by the National Natural Science Foundation of China (52025132, 21621091, 22021001, 22121001, 22275207 and T2241022)the National Science Foundation of Fujian Province of China (2022J02059)+3 种基金the State Key Laboratory of Bio-Fibers and Eco-Textiles (Qingdao University) (KFKT202221)the 111 Project (B17027, B16029)the Science and Technology Projects of Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (RD2022070601)the Tencent Foundation (The XPLORER PRIZE)。
文摘Membrane separation technology with the ability to regulate gas/liquid transport and separation is critical for environmental fields, such as sewerage treatment, multiphase separation, and desalination. Although numerous membranes can dynamically control liquid-phase fluids transport via external stimuli, the transport and separation of gas-phase fluids remains a challenge. Here, we show a temperature-regulation liquid gating membrane that allows in-situ dynamically controllable gas/liquid transfer and multiphase separation by integrating a thermo-wettability responsive porous membrane with functional gating liquid. Experiments and theoretical analysis have demonstrated the temperature-regulation mechanism of this liquid gating system, which is based on thermo-responsive changes of porous membrane surface polarity, leading to changes in affinity between the porous membrane and the gating liquid. In addition, the sandwich configuration with dense Au-coated surfaces and heterogeneous internal components by a bistable interface design enables the liquid gating system to enhance response sensitivity and maintain working stability. This temperature-regulation gas/liquid transfer strategy expands the application range of liquid gating membranes,which are promising in environmental governance, water treatment and multiphase separation.
基金National Key R&D Program of China(No.2017YFA0304203)National Energy R&D Center of Petroleum Refining Technology(RIPP,SINOPEC),Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China(IRT_17R70)+3 种基金National Natural Science Foundation of China(Nos.61975103,61875108,61775125 and 11434007)Major Special Science and Technology Projects in Shanxi(No.201804D131036)111 Project(No.D18001)Fund for Shanxi’1331KSC’。
文摘The self-absorption effect in laser-induced breakdown spectroscopy(LIBS)reduces the accuracy of quantitative measurement results.The self-absorption-free LIBS(SAF-LIBS)has been proved to directly capture the optically thin plasma spectra by setting an appropriate exposure time.In this work,a novel SAF-LIBS technique with high repetition rate acousto-optic gating is developed,in which an acousto-optic modulator is used as the shutter to diffract the optically thin fluorescence,and a high repetition rate laser is used to produce quasi-continuous plasmas to enhance the integral spectral intensity,so that the CCD spectrometer can replace an intensified CCD(ICCD)and echelle spectrometer in SAF-LIBS.Experimental results show that the average absolute prediction error of aluminum is reduced to 0.18%,which is equivalent to that of traditional SAF-LIBS.This technique not only effectively shields continuous background radiation and broadened spectral lines in optically thick plasma,but also has advantages of miniaturization,low cost,convenience and reliability.
基金supported by the Major Project of NSFC(51690161)the Student Innovation Program Major Project of Northeastern University(ZD1708)
文摘High pressure die casting(HPDC) is a kind of near net shape manufacturing method. However, air entrapment in HPDC parts has serious effects upon the casting quality. In order to reduce the air entrapment defects in a AlSi10 MnMg alloy thin-wall longitudinal load-bearing beam produced by HPDC, different gating systems were designed and simulated by software Flow-3D to evaluate the entrapped air. Simulation results showed that when the beam is produced by the original designed gating system with a middle ingate, there exist obvious air entrapments in the critical area; the volume of air entrapment was reduced by replacing the middle ingate to an overflow well, and the filling of molten metal became more stable. When the middle ingate was removed for further improvement, the volume of air entrapment was decreased drastically. The parts with glossy surface and good microstructure have been successfully produced by using the final optimized gating system based on simulation results.
基金supported by the National Natural Science Foundation of China under Grant Nos 51872328,11622437,11574394,11774423 and 11822412the Strategic Priority Research Program of Chinese Academy of Sciences under Grant No XDB30000000+5 种基金the Ministry of Science and Technology of China under Grant No 2016YFA0300504the Fundamental Research Funds for the Central Universitiesthe Research Funds of Renmin University of China(RUC)(15XNLQ07,18XNLG14,19XNLG17)supported by the National Natural Science Foundation of China under Grant Nos 11774007 and U1832214supported by the Outstanding Innovative Talents Cultivation Funded Programs 2018 of Renmin University of Chinasupported by the U.S. Department of Energy,Office of Science,Basic Energy Sciences,Division of Materials Sciences and Engineering
文摘We report protonation in several compounds by an ionic-liquid-gating method, under optimized gating conditions.This leads to single superconducting phases for several compounds. Non-volatility of protons allows post-gating magnetization and transport measurements. The superconducting transition temperature Tc is enhanced to 43.5 K for FeSe0.93S0.07, and 41 K for Fe Se after protonation. Superconducting transitions with Tc^15 K for ZrNCl,~7.2 K for 1-TaS2, and ~3.8 K for Bi2Se3 are induced after protonation. Electric transport in protonated FeSe0.93S0.07 confirms high-temperature superconductivity. Our ^1H nuclear magnetic resonance(NMR)measurements on protonated Fe Se1-xSx reveal enhanced spin-lattice relaxation rate 1/^1T1 with increasing x,which is consistent with the LDA calculations that H+ is located in the interstitial sites close to the anions.
文摘The gating system of a cylindrical magnesium casting has been designed by using multiple objective optimiza- tion and Taguchi method.Mold filling and solidification processes were simulated by using MAGMASOFT(?). The simulation results indicate that the gating system design has a significant effect on the quality of magne- sium castings.In an effort to obtain the optimal design of gating system,the signal-to-noise (S/N) ratio was used to analyze the effect of various gating designs on cavity filling and casting quality by using a weighting method based on the design of an orthogonal array.Four gating system parameters,namely,ingate height, ingate width,runner height,runner width,were optimized with a consideration of multiple objective criteria including filling velocity,shrinkage porosity and product yield.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11174294,11174291,11374302,11304319,U1332209,U1432251 and U1532153the China Postdoctoral Science Foundation under Grant No 2015M582020+1 种基金the Program of Users with Excellence,the Hefei Science Center of Chinese Academy of Sciencesthe CAS/SAFEA International Partnership Program for Creative Research Teams of China
文摘The electronic doping effect on both the superconductivity and the nematic order in the FeSe nanoflake are investigated by using the electric-double-layer transistor configuration. The superconductivity can be effectively controlled by electronic doping, and the onset superconducting transition temperature Tc reaches as high as 45 K at a gate voltage Of Vg = 4 V. Meanwhile, the nematic phase is gradually suppressed with the increase of electronic doping (or Vg). The results provide an effective method with variable charge doping for investigation of the rich physics in the FeSe superconductor.
基金Project supported by the National Key R&D Program of China(Grant No.2017YFB0405202)the National Natural Science Foundation of China(Grant Nos.61690221,91850209,and 11774277)。
文摘A convolutional neural network is employed to retrieve the time-domain envelop and phase of few-cycle femtosecond pulses from transient-grating frequency-resolved optical gating(TG-FROG) traces.We use theoretically generated TGFROG traces to complete supervised trainings of the convolutional neural networks,then use similarly generated traces not included in the training dataset to test how well the networks are trained.Accurate retrieval of such traces by the neural network is realized.In our case,we find that networks with exponential linear unit(ELU) activation function perform better than those with leaky rectified linear unit(LRELU) and scaled exponential linear unit(SELU).Finally,the issues that need to be addressed for the retrieval of experimental data by this method are discussed.
基金Supported by the National Natural Science Foundation Program of China under Grant Nos 11274302,11474276 and 61290303
文摘The carrier-density-dependent spin relaxation dynamics for modulation-doped GaAs/Al0.3 Gao,TAs quantum wells is studied using the time-resolved magneto-Kerr rotation measurements. The electron spin relaxation time and its in-plane anisotropy are studied as a function of the optically injected electron density, Moreover, the relative strength of the Rashba and the Dresselhaus spin-rbit coupling fields, and thus the observed spin relaxation time anisotropy, is further tuned by the additional excitation of a 532nm continuous wave laser, demonstrating an effective spin relaxation manipulation via an optical gating method.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61605248 and 61505261)
文摘GHz single-photon detector (SPD) is a crucial part in the practical high speed quantum key distribution (QKD) system. However, any imperfections in a practical QKD system may be exploited by an eavesdropper (Eve) to collect information about the key without being discovered. The sine wave gating SPD (SG-SPD) based on InGaAs/InP avalanche photodiode, one kind of practical high speed SPD, may also contain loopholes. In this paper, we study the principle and characteristic of the SG-SPD and find out the filtering loophole of the SG-SPD for the first time. What is more, the proof-of-principle experiment shows that Eve could blind and control Bob's SG-SPD by exploiting this loophole. We believe that giving enough attention to this loophole can improve the practical security of the existing QKD system. GHz single-photon detector (SPD) is a crucial part in the practical high speed quantum key distribution (QKD) system. However, any imperfections in a practical QKD system may be exploited by an eavesdropper (Eve) to collect information about the key without being discovered. The sine wave gating SPD (SG-SPD) based on InGaAs/InP avalanche photodiode, one kind of practical high speed SPD, may also contain loopholes. In this paper, we study the principle and characteristic of the SG-SPD and find out the filtering loophole of the SG-SPD for the first time. What is more, the proof-of-principle experiment shows that Eve could blind and control Bob's SG-SPD by exploiting this loophole. We believe that giving enough attention to this loophole can improve the practical security of the existing QKD system.
基金Project supported by the National Key Research and Development Projects of China(Grant Nos.2016YFA0202300 and 2018FYA0305800)the National Natural Science Foundation of China(Grant Nos.61674170 and 61888102)+1 种基金the K.C.Wong Education Foundation,the Strategic Priority Research Program of Chinese Academy of Sciences(Grant Nos.XDB30000000 and XDB28000000)the Youth Innovation Promotion Association of Chinese Academy of Sciences(Grant No.Y201902).
文摘We report the electrical transport properties of InSe flakes electrostatically gated by a solid ion conductor.The large tuning capability of the solid ion conductor as gating dielectric is confirmed by the saturation gate voltage as low as^1 V and steep subthreshold swing(83 mV/dec).The p-type conduction behavior of InSe is obtained when negative gate voltages are biased.Chemical doping of the solid ion conductor is suppressed by inserting a buffer layer of hexagonal boron nitride(h-BN)between InSe and the solid-ion-conductor substrate.By comparing the performance of devices with and without h-BN,the capacitance of solid ion conductors is extracted to be the same as that of^2 nm h-BN,and the mobility of InSe on solid ion conductors is comparable to that on the SiO2 substrate.Our results show that solid ion conductors provide a facile and powerful method for electrostatic doping.
基金Project supported by the Research Foundation of Education Bureau of Guangxi Autonomous Region of ChinaInitial Research Fund of Guangxi Normal University, and the Research Fund of Key Laboratory Construction in College of Electronic Engineering of Guangxi Normal University
文摘The classical model of voltage-gated ion channels assumes that according to a Markov process ion channels switch among a small number of states without memory, but a bunch of experimental papers show that some ion channels exhibit significant memory effects, and this memory effects can take the form of kinetic rate constant that is fractal. Obviously the gating character of ion channels will affect generation and propagation of action potentials, furthermore, affect generation, coding and propagation of neural information. However, there is little previous research on this series of interesting issues. This paper investigates effects of fractal gating of potassium channel subunits switching from closed state to open state on neuronal behaviours. The obtained results show that fractal gating of potassium channel subunits switching from closed state to open state has important effects on neuronal behaviours, increases excitability, rest potential and spiking frequency of the neuronal membrane, and decreases threshold voltage and threshold injected current of the neuronal membrane. So fractal gating of potassium channel subunits switching from closed state to open state can improve the sensitivity of the neuronal membrane, and enlarge the encoded strength of neural information.
基金This work is supported by the National Nature Science Foundation of China(Grant Nos.61502101 and 61501247)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20171458)+4 种基金the Six Talent Peaks Project of Jiangsu Province,China(Grant No.2015-XXRJ-013)the Natural science Foundation for colleges and universities of Jiangsu Province,China(Grant No.16KJB520030)the Research Innovation Program for College Graduates of Jiangsu Province,China(Grant No.KYCX17_0902)the Practice Innovation Training Program Projects for the Jiangsu College Students(Grant No.201810300016Z)and the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘The delegating private quantum computation(DQC)protocol with the universal quantum gate set{X,Z,H,P,R,CNOT}was firstly proposed by Broadbent et al.[Broadbent(2015)],and then Tan et al.[Tan and Zhou(2017)]tried to put forward a half-blind DQC protocol(HDQC)with another universal set{H,P,CNOT,T}.However,the decryption circuit of Toffoli gate(i.e.T)is a little redundant,and Tan et al.’s protocol[Tan and Zhou(2017)]exists the information leak.In addition,both of these two protocols just focus on the blindness of data(i.e.the client’s input and output),but do not consider the blindness of computation(i.e.the delegated quantum operation).For solving these problems,we propose a full-blind DQC protocol(FDQC)with quantum gate set{H,P,CNOT,T},where the desirable delegated quantum operation,one of{H,P,CNOT,T},is replaced by a fixed sequence(H,P,CZ,CNOT,T)to make the computation blind,and the decryption circuit of Toffoli gate is also optimized.Analysis shows that our protocol can not only correctly perform any delegated quantum computation,but also holds the characteristics of data blindness and computation blindness.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11125416,and 11121091)the National Basic Research Program of China(Grant No.2013CB922403)
文摘Both polarization gating (PG) and double optical gating (DOG) are productive methods to generate single attosecond (as) pulses. In this paper, considering the ground-state depletion effect, we investigate the wavelength-dependence of the DOG method in order to optimize the generation of single attosecond pulses for the future application. By calculating the ionization probabilities of the leading edge of the pulse at different driving laser wavelengths, we obtain the upper limit of duration for the driving laser pulse for the DOG setup. We find that the upper limit duration increases with the increase of laser wavelength. We further describe the technical method of choosing and calculating the thickness values of optical components for the DOG setup.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.51671099 and 11974149)the Open Foundation Project of Jiangsu Key Laboratory of Thin Films(Grant No.KJS1745)+1 种基金the Program for Changjiang Scholars and Innovative Research Team in University,China(Grant No.IRT16R35)the Fundamental Research Funds for the Central Universities,China.
文摘We report a tunable transverse magnetoresistance of the planar Hall effect(PHE),up to 48%in the Ni80Fe20/HfO2 heterostructures.This control is achieved by applying a gate voltage with an ionic liquid technique at ultra-low voltage,which exhibits a gate-dependent PHE.Moreover,in the range of 0-V to 1-V gate voltage,transverse magnetoresistance of PHE can be continuously regulated.Ferromagnetic resonance(FMR)also demonstrates the shift of the resonance field at low gate voltage.This provides a new method for the design of the electric field continuous control spintronics device with ultra-low energy consumption.
基金Supported by the National Natural Science Foundation for Distinguished Young Scholars of Hebei Province under Grant Nos C2015202340 and C2013202244the Foundation for Outstanding Talents of Hebei Province under Grant No C201400305+3 种基金the National Natural Science Foundation of China under Grant Nos 11247010,11175055,11475053,11347017,31400711 and 11647121the NIH R01 under Grant No HL059949-18the Foundation for the Science and Technology Program of Higher Education Institutions of Hebei Province under Grant No QN2016113the Scientific Innovation Fund for Excellent Young Scientists of Hebei University of Technology under Grant No 2015010
文摘As a member of the inwardly rectifying channel (Kir) family, Kir2.1 allows to influx the cell more easily than to efflux, a biophysical phenomenon named inward rectification. The function of Kir2.1 is to set the resting membrane potential and modulate membrane excitability. It has been reported that residue E224 plays a key role in regulating inward rectification. The mutant Kir2.1 (E224G) displays weaker inward rectification than the WT channel. Gating of Kir2.1 depends on the membrane lipid, PIP<sub>2</sub>, such that the channel gates are closed in the absence of PIP<sub>2</sub>. Here we perform electrophysiological and computational approaches, and demonstrate that E224 also plays an important role in the PIP<sub>2</sub>-dependent activation of Kir2.1 in addition to its influence on inward rectification. The E224G mutant takes 4.5 times longer to be activated by PIP<sub>2</sub>. To probe the mechanism by which E224G slows the channel opening kinetics, we perform targeted molecular dynamics simulations and find that the mutant weakens the interactions between CD-loop and C-linker (H221-R189) and the adjacent G-loops (R312-E303) which are thought to stabilize the open state of the channel in our previous work. These data provide new insights into the regulation of Kir2.1 channel activity and suggest that a common mechanism may be involved in the distinct biophysical processes, such as inward rectification and PIP<sub>2</sub>-induced gating.
文摘Mice subjected to an irregular light-dark cycle are known to lose their capacity to synchronize their behavioral rhythm to environmental light, and to show endophenotypes related to depressive disorders. Here we observed that a susceptible strain of mice (C3H/HeJ) subjected to an irregular 3.5 hr:3.5 hr light-dark cycle showed an enhanced acoustic startle reflex and deficits in prepulse inhibition. As impaired sensorimotor gating is associated with the onset of a variety of mental disorders such as schizophrenia and major depressive disorder, irregular environmental light without circadian photo-entrainment may cause stress that has the potential to be involved in humans’ susceptibility to neuropsychiatric abnormalities.
基金supported by the National Basic Research Program of China (973 Program) (2012CB518502)the National Natural Science Foundation of China (81102630)+2 种基金the Shanghai Leading Academic Discipline Project (S30304,B112)the Science Foundation of Shanghai Municipal Commission of Science and Technology (09DZ1976600,09dZ1974303,10DZ1975800)the Fudan Science Foundation for Young (09FQ07)
文摘Mechanosensitive(MS) ion channels play an important role in various physiological processes.Although the determination of the structure of mechanosensitive channel of large conductance(MscL) makes the simulation study possible,it has not so far been possible to directly simulate the gating mechanism of MscL in atomic detail.In this article,MscL has been studied via molecular dynamic(MD) simulations to gain a detailed description of the sensitivity to lateral tension and the gating pathway.MscL undergoes conformational rearrangement in sustaining lateral tension,and the open state is obtained when 2.0 MPa lateral tension is directly applied on the pure protein.During the opening process,Loop region responds to tension first,and the mechanical sensitivity is followed by S1 domain.Transmembrane(TM) bundle is the key position for channel opening,and the motion of TM1 helices finally realizes the significant expansion of the constricted gating pore.C-terminus domain presents expansion later during the TM opening.In our study,return of the whole protein to the initial closed state is achieved only in the early opening stage.During the relaxation from the open state,the TM helices are the most mobile domain,which is different from the opening process.