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CLINICAL CHARACTERISTICS AND BASIC RESEARCH DEVELOPMENT OF PEUTZ- JEGHERS SYNDROME
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作者 何晓东 毛一雷 +2 位作者 贲勇 马超 张振寰 《Chinese Medical Sciences Journal》 CAS CSCD 2001年第1期49-51,共3页
To improve clinical knowledge of Peutz- Jeghers syndrome. Methods. Eight patients with Peutz- Jeghers syndrome from 1984 to 1998 in our hospital were retrospectively reviewed and analyzed in the present study. Result.... To improve clinical knowledge of Peutz- Jeghers syndrome. Methods. Eight patients with Peutz- Jeghers syndrome from 1984 to 1998 in our hospital were retrospectively reviewed and analyzed in the present study. Result. The result of this analysis showed that there were 4 patients appeared with family histories of Peutz- Jeghers syndrome. All of the included patients admitted to the hospital with various complications, and eventually received surgical interventions for these complications, among which, 6 of them had intestinal obstructions mostly (5/6) due to small bowel intussusception, and 2 of them suffered with hemafecia. Post- operative recoveries were generally satisfactory with zero mortality. Conclusion. Peutz- Jeghers syndrome is an uncommon digestive dominant hereditary disease. The diagnosis of it with history, symptoms, signs, and proper examinations usually is not difficult. Surgical interventions are necessary once complications occur. 展开更多
关键词 SYNDROME PIGMENTATION POLYPOSIS lkb1 gene
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