Twenty years of changes in the disease assessment method of the Global Initiative for Chronic Obstructive Lung Disease

The Global Initiative for Chronic Obstructive Lung Disease(GOLD)has been changing for nearly 20 years.GOLD has moved from single assessment using spirometry to a more comprehensive assessment of chronic obstructive pulmonary disease using spirometry,symptoms and exacerbation history.And subsequently,a new assessment system for chronic obstructive pulmonary disease separated spirometric grades from the old assessment system,and classified patients only according to their symptoms and history of exacerbation.The distribution,clinical characteristics,treatment,and prognosis of the new subgroups were different from the old ones.In this review,we will present a brief profile of changes made to the disease assessment method of GOLD,based on the relevant existing literature.

Does the 2017 global initiative for chronic obstructive lung disease revision really improve the assessment of Chinese chronic obstructive pulmonary disease patients?A multicenter prospective study for more than 5 years

Background:The Global Initiative for Chronic Obstructive Lung Disease(GOLD)2017 proposed a new classification that reclassified many chronic obstructive pulmonary disease(COPD)patients from group D to B.However,there is a paucity of data related to the comparison between reclassified and non-reclassified COPD patients in terms of long-term prognosis.This study aimed to investigate long-term outcomes of them and determine whether the GOLD 2017 revision improved the assessment of COPD patients.Methods:This observational,multicenter,prospective study recruited outpatients at 12 tertiary hospitals in China from November 2016 to February 2018 and followed them up until February 2022.All enrolled patients were classified into groups A toDbased on GOLD 2017,and the subjects in group B included patients reclassified from group D to B(group DB)and those remaining in group B(group BB).Incidence rates and hazard ratios(HRs)were calculated for the exacerbation of COPD and hospitalization in each group.Results:We included and followed up 845 patients.During the first year of follow-up,the GOLD 2017 classification had a better discrimination ability for different risks of COPD exacerbation and hospitalization than GOLD 2013.Group DB was associated with a higher risk of moderate-to-severe exacerbation(HR=1.88,95%confidence interval[CI]=1.37-2.59,P<0.001)and hospitalization for COPD exacerbation(HR=2.23,95%CI=1.29-3.85,P=0.004)than group BB.However,during the last year of follow-up,the differences in the risks of frequent exacerbations and hospitalizations between group DB and BB were not statistically significant(frequent exacerbations:HR=1.02,95%CI=0.51-2.03,P=0.955;frequent hospitalizations:HR=1.66,95%CI=0.58-4.78,P=0.348).The mortality rates of the two groups were both approximately 9.0%during the entire follow-up period.Conclusions:The long-term prognosis of patients reclassified into group B and of those remaining in group B was similar,although patients reclassified from group D to group B had worse short-term outcomes.The GOLD 2017 revision could improve the assessment of Chinese COPD patients in terms of long-term prognosis.

Global Development Initiative:An International Public Goods to Promote Common Development

The world today is facing turbulence and change,and global development is at a crossroads.At this critical juncture,President Xi Jinping put forth the Global Development Initiative(GDI)with the theme“implementing the 2030 Sustainable Development Agenda for more robust,greener and healthier global development”at the 76th General Assembly of the United Nations,which sheds light on the direction of global development.The GDI,proposed by China,has galvanized support from the international community as an international public goods to promote common development.Following the historical trends of human development,the GDI breaks through the limitations of the hegemonic stability theory and the free-riding curse to expand and innovate the theoretical perception of international public goods with the right approach to principles and interests.With a people-oriented approach and the basic principles of green and innovative development,the GDI both addresses urgent challenges and attaches importance to enhancing development capabilities and creating supporting conditions to offer a holistic solution to global challenges.Through the implementation of multiple pathways under international cooperation,the GDI will build a consensus on global development,increase the momentum of global development,and play an important role in creating a community with a shared future for mankind.

The Global Significance of the Belt and Road Initiative

Over the past three years,the great appeal and bright future of the Belt and Road Initiative has presented sharp contrast with the trends emerged in some regions,such as widespread populism,rising protectionism,the awakening thought of antiglobalization and hindered frustrated

Preliminary validation of Global Leadership Initiative on Malnutrition criteria in cancer patients:A cross-sectional study

Background:The Global Leadership Initiative on Malnutrition(GLIM)has been used in China since 2019.This study aimed to test the use of the GLIM criteria in Chinese cancer patients and to compare the diagnostic performance of the GLIM criteria with the Patient-Generated Subjective Global Assessment(PG-SGA)and modified PG-SGA(mPG-SGA). Methods:A total of 2,000 cancer patients were consecutively screened using the Nutritional Risk Screening 2002 instrument on ad-mission.Patients at nutritional risk(Nutritional Risk Screening 2002 score≥3)were enrolled to obtain the complete GLIM,PG-SGA,and mPG-SGA criteria.To evaluate the convergent validity,Spearman correlation analysis was used to compare the test-retest reliability of the GLIM criteria and its results with the scores of various nutritional tools and objective parameters.Kruskal-Wallis tests and χ2 tests were used to test the discriminant validity among groups with different nutritional status.We calculated the sensitivity,specificity,positive predictive value,and negative predictive value for the various tools. Results:There were 562 patients found to be at nutritional risk,accounting for 28.1%of all patients.One hundred seventy-four patients(8.7%)were diagnosed as moderately malnourished,and 333 patients(16.6%)were severely malnourished based on the PG-SGA.When assessed using the GLIM criteria,185 patients(9.3%)were diagnosed as moderately malnourished and 311 patients(15.5%)were severely malnourished.The content validity of the GLIM criteria was 95%,evaluated by 60 medical staff members.The test-retest reliability was good.For the diagnosis of malnutrition versus the PG-SGA,the sensitivity of the GLIM was"good"(90.5%;95%confidence interval[95%CI]=88.0%-93.1%),with a positive predictive value of 92.5%(95%CI=90.2%-94.9%),but the spec-ificity and negative predictive value were"poor."Similar results were obtained when the mPG-SGA was used as the criterion. Conclusions:Overall,this cross-sectional study suggests that the GLIM criteria comprise a valid and reliable tool to assess the nutri-tional status of Chinese cancer patients.

GDI and GSI: China’s New Propositions for Global Governance

In the post-pandemic era,the global economic and security landscapes are fraught with complexities and uncertainties.Among them,four risk flashpoints merit attention:Certain countries are raising interest rates to subdue inflation,despite their already high levels of debt;the bulk commodities market is experiencing volatility,leading to global turbulence and change;trade protectionism is at the forefront of major-power rivalry in political and economic spheres;and regional security crises are compounding international tensions.Behind those flashpoints are contradictions that obstruct world peace and progress,including development imbalances,governance gaps,and structural tensions in global security.In the face of uncertainties,it is crucial for China to seize strategic opportunities and transform crises into favorable situations.China has launched the Global Development Initiative(GDI)and the Global Security Initiative(GSI)to contribute to global prosperity and security.The two initiatives demonstrate China’s commitment to addressing global deficits in peace,development,security,and governance.

Belt and Road Initiative Boosts Win-win Cooperation

A growing number of countries and regions on the Eurasian continent have achieved consensus on the initiative.SINCE proposing the Belt and Road Initiative in 2013,Chinese President Xi Jinping has visited 37 countries and introduced the initiative on various occasions.

AN INITIAL PROBE INTO DENG XIAOPING'S GLOBAL STRATEGIC THINKING

As the chief architect of China’s reform and opening up and a leading personalityof world class,Deng Xiaoping played a historical role in China’s political and e-conomic development in the period of its reform and opening.And so did his globalstrategic thinking,which not only had a decisive bearing on the adjustments,andchanges in China’s foreign strategy and policies,but also made a great

An In-depth Interpretation of the Universal Declaration of Human Rights With the Common Values of Humanity As the Research Paradigm

Interpreting the Universal Declaration of Human Rights from political,juridical and philosophical perspectives is es-sential for promoting the guiding principles of the Declaration,build-ing consensus on human rights,and advancing human rights practice in the new historical context.To conduct an academic,systematic in-terpretation of the Declaration that conforms to the trends of the times and answers the fundamental questions of the world,it is necessary to find a new research paradigm.The common values of humanity,namely peace,development,equity,justice,democracy and freedom,put forward by Xi Jinping,general secretary of the Communist Party of China(CPC)Central Committee,provide the most explanatory and penetrating scientific paradigm for reaching the issue.This paper an-alyzes and reflects on the views,value foundation and principled(con-tractual)consensus of human rights in the Declaration,and narrates and foresees the far-reaching significance of the three global initia-tives(namely,the Global Development Initiative,the Global Security Initiative,and the Global Civilization Initiative)with the common val-ues of humanity as the soul in advancing the modernization of global human rights governance and building a new form of human rights civilization.

A Review on D 614G Mutation with Bangladesh Scenario

With the COVID-19 pandemic, disparities between the infection rate and death rate in different countries become a major concern. In some countries, lower mortality rate compared to others can be explained by better testing capacity and intensive care facilities. Complete SARS-CoV-2 genome sequences from different countries of the world are continually submitted to Global Initiative for Sharing All Influenza Data using Next Generation Sequencing method. A SARS-CoV-2 variant with a D 614G Mutation in the spike (S) protein has become the most dominant form in the global pandemic. There are a number of ongoing studies trying to relate this mutation with the infectivity, mortality, transmissibility of the virus and its impact on vaccine development. This review aims to accumulate the major findings from some of these studies and focus its future implication. Some studies suggested D 614G strain has increased binding capacity, it affects more cells at a faster rate, so has a high transmissibility. Patients infected with this strain were found with high viral load. But still now there is no such evidence that this strain produces more severe disease as well as increased mortality. The structural change of spike protein produced by D 614G mutation was minor and did not hamper the vaccine efficacy. Some studies showed antibodies produced against D614 strain can neutralize G614 strain and vice versa. Whenever a mutation occurs in spike protein there are always chances of affecting the infectivity, transmissibility, vaccine efficacy. Therefore, more studies are required to find out the overall effect of D 614G mutation.

统筹全球发展倡议和全球安全倡议的几点思考

China’s Global Development Initiative(GDI)and Global Security Initiative(GSI)symbolize the important innovations,in theory and in practice,resulting from President Xi Jinping’s thought on diplomacy in recent years.Both initiatives were proposed by President Xi,who has been standing with the people and supporting laws for the development of human society.These initiatives disseminate Chinese wisdom and inputs in responding to the questions posed by the world,by our times,and by history,thus having a significant impact on China’s peaceful development,as well as on global prosperity and progress.Presently,the once-in-a-century changes that shape the world today are evolving rapidly,and the international security situation is undergoing complex transformations.To address urgent issues and make new contributions to global peace and development,it is crucial to systematically study and deeply reflect on the GDI and the GSI and seek synergy between the two.

乌克兰危机的影响及启示

The escalation of the Ukraine crisis over the past year has exerted a significant and far-reaching impact on international politics,the economy,and the military.The international order is collapsing gradually in the post-Cold War era.International politics is becoming increasingly camp-oriented,the international economy is tending more and more toward antiglobalization,the global arms race is growing progressively fiercer,and the application of new military technologies is steering humankind to a new era of war.The United States has used Ukraine to fight a proxy war with Russia and has become the principal beneficiary of this crisis by utilizing this opportunity to strengthen its alliance system,stabilize itself,control Europe,and restrain Russia.Ukraine's capacity and willingness to fight have intensified with Western support,and neither side is willing to reconcile.A standoff between Russia and Ukraine would prolong the conflict,escalating the risk of nuclear war.However,the possibility of negotiations to contain the crisis cannot be ruled out.The emergency has reminded Europe of the value of strategic autonomy and has warned Asian countries to prohibit the United States from launching new proxy wars in the region.China's Global Security Initiative and Position Paper on the Political Settlement of the Ukraine Crisis offer innovative ideas that can help the concerned parties to withdraw from the crisis and can aid the international community in building lasting peace.

中国三大全球倡议的战略逻辑

With the answers China has found in resolving its challenges,the Global Development Initiative,Global Security Initiative,and Global Civilization Initiative have actively responded to the questions posed by the world and the times,establishing the direction for countries worldwide to jointly build a human community with a shared future.This article discusses the historical background,strategic connotations,and philosophies of these three initiatives,offering insight into their holistic approach and development perspective in assessing the world’s evolution.Furthermore,these initiatives consider both domestic and international imperatives and ensure security while pursuing development.The strategic thinking that the world should seek sustainable development through cooperation on the basis of civilizations highlights a people-centered orientation;advocates respecting others’interests in the pursuit of one’s own and advancing common interests of all;follows a result-oriented approach;promotes win–win collaborations;and emphasizes China’s contributions.Finally,the author proposes strategic pathways for implementing these global initiatives:namely,devising strategies centered on development;enhancing reciprocal learning between civilizations;avoiding excessive securitization;upholding the principle of extensive consultation,joint contribution,and shared costs and benefits;and demonstrating China’s sense of duty as a major country through pragmatic actions.

浅析全球安全倡议的实施路径

In the current era of changes unseen in a century,humanity is caught up in a deteriorating security environment on a global scale.By proposing the Global Security Initiative(GSI),China has offered its wisdom and a solution toward building a community of shared security for humanity.After a brief review of the historical evolution of the global security mechanism,the present study analyzes the main ideas and contemporary values making up the GSI.Meanwhile,based on the approaches proposed in and the spirit of the GSI Concept Paper,the authors uncover the dialectical relationship between the GSI,the Global Development Initiative,and the Global Civilization Initiative,which are all included in the Law on Foreign Relations of the People’s Republic of China adopted on June 28,2023.Furthermore,the authors recommend three practical paths toward implementing the GSI:a path toward shortterm goals,a path toward medium-term goals,and a path toward longterm goals.The success of the GSI needs the concerted efforts of all countries.China is not only an active advocate of the GSI but has also been striving to enhance its capability in safeguarding global security,implement the GSI vigorously,and spearhead a new type of global governance.

Sustainable Data Analytics for Environmental Performance Monitoring in Dynamic Supply Chain Infrastructure

The increase in climate change raises the awareness of societal stakeholders to act as key-drivers in motivating and pushing corporations to monitor their sustainability data transparency, analyse their operations performance, and improve their operations related to environment, social governance, and corporate social responsibility. This paper evaluates the current importance of the societal stakeholders that impact the compliance of companies towards these environmental, social and governance practices in their supply chain operations. The latest review on the sustainability reporting and its data analytics are carried out, followed by a review of the development of a sustainability reporting and data analytics model, including sustainability software and online platforms in facilitating and supporting supply chain practitioners in their decision-making process. The model has been further developed as a dashboard and applied to a maritime supply chain firm. A case analysis has been conducted to illustrate the importance of analytics data in supporting complex decision-making process. Additional intelligent data analytics functionalities are recommended as future development for the sustainability reporting and data analytics dashboard in supply chain operations.

Evaluation of Sustainability Reporting Practices in Turkey

The purpose of the present study is to determine the reflection of sustainability reporting （SR）, which gained momentum considerably during the recent years, on the organizations that are active in Turkey. Turkish businesses that carried out SR during January 1, 2005 and June 1, 2015 were included in the study. Altogether, 186 sustainability reports containing 6,240 pages of a total of 80 businesses were examined. Data obtained from these reports were classified into various categories. According to the results, it was determined that 84% of the reporting businesses reported according to Global Reporting Initiative （GRI） principles and preferred G3 framework （40%）; and the maximum number of reporting was published in 2014. The present study is the first research article including all businesses making SR in Turkey with all details.

China’s Views on Solving the Yemeni Issue Within the Framework of Global Security Initiative

Yemen is a traditional friendly country of China and an important partner of China in the Arabian Peninsula.As a result of the recur-ring conflicts in Yemen,its economic situation has been deterio-rating.China’s bilateral trade volume and direct investment with Yemen have been directly affected by the war in Yemen and have fluctuated significantly.The security and happiness of the Yemeni people and the effective protection of people’s rights cannot be achieved without stable internal social relations and a peaceful external environment.In 2022,President Xi Jinping pro-posed the Global Security Initiative(GSI),calling on countries to adapt to the profoundly changing international landscape in the spirit of solidarity,and to address security challenges with a win-win mindset.In 2023,China releases the Global Security Initiative Concept Paper.China’s idea for solving the Yemen issue is a the-oretical and institutional reflection on war,peace and develop-ment based on a reflexion of the unequal world hegemonic order,centreing on equality and the care for humanity.

The Belt and Road Augurs a Community of Shared Destiny

CHINESE President Xi Jinping has mentioned"a community of shared destiny"more than 100 times during the past four years on momentous occasions at home and abroad,thereby expressing China’s undertaking to achieve this grand mission.In 2017,President Xi Jinping extended New Year greetings to Chinese compatriots and people around the world,and spoke of Chinese people’s hopes for a better life for people everywhere.

The Belt and Road Initiative,New-type Globalization and Major-country Relations

most of the countries along the Belt and Road belong to low-and medium-income countries, their main challenge is how to achieve development. East Asia and China relied on the export-oriented strategy to have achieved industrialization. However, in the next period, the growth rate of international trade will be significantly lower than that of GDP. Coupled with the de-globalization trend in developed countries, the global development needs new ideas. China and countries along the Belt and Road can promote industrialization centering on infrastructure construction, with the manufacturing industry as the core and developing countries cooperation as the main content to promote new-type globalization. China has leading manufacturing and trade capacity of the world, and strategically advocates principles of extensive consultation, shared benefits and joint contribution, therefore, the Belt and Road Initiative has a profound driving power. It is expected by 2030, 2.4 billion people with low-income along the Belt and Road will be transformed into high-income population, and then China would have a population of 1.4 billion with high income.

Global Attractors for the Initial Value Problems of Cohn-Hilliard Equations on Compact Manifolds

In this paper we establish some theorems which are concerned with the equivalent norms of Sobolev spaces on a Riemannian manifold. Using the theorems we prove the existence of global attractors for the initial value problem of Cahn-Hilliard equations. The estimates of the upper bounds of Hausdorff and fractal dimensions for the global attractors are also obtained.