期刊文献+
共找到13篇文章
< 1 >
每页显示 20 50 100
Wound healing activity of Delonix elata stem bark extract and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside in rats 被引量:1
1
作者 Pradeepa Krishnappa Krishna Venkatarangaiah +2 位作者 Venkatesh Santosh Kumar Shimoga Rajanna Rebijith Kayattukandy Balan 《Journal of Pharmaceutical Analysis》 SCIE CAS 2016年第6期389-395,共7页
Delonix elata L.is a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases,liver diseases and rheumatic problems.However,systematic evaluation of its wound healing activity is lackin... Delonix elata L.is a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases,liver diseases and rheumatic problems.However,systematic evaluation of its wound healing activity is lacking.Thus,in the present study,we aimed to assess the wound healing activity of D.elata stem bark extract(DSE) and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside(QRPG) in rats.The formulations effects on wound healing were assessed by the wound contraction rate,epithelialization period,tensile strength,content of the hydroxyproline,hexosamine and uronic acid in granulation tissue,histopathological studies and Col 1 α(I) expression level in wound tissue by reverse transcription polymerase chain reaction(RT-PCR) study.The topical application of DSE ointment caused faster epithelialization,significant wound contraction(100%),and better tensile strength(710.5 ± 10.5 g/cm^2),while QRPG showed wound epithelialization with 98.2%contraction,better than that of the control group(78.18%).The biochemical analysis of granulation tissue revealed that DSE and QRPG significantly increased hydroxyproline,hexosamine and uronic acid content.A significant increase in the expression of Col 1 α(I) was observed in the wound tissue of DSE and QRPG treated rats.DSE and QRPG were shown to enhance wound healing by increasing collagen synthesis through upregulation of Col 1 α(I),thus validating ethnomedicinal uses. 展开更多
关键词 Delonix elata Quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside (QRPG) Wound HEALING HYDROXYPROLINE Tensile strength
下载PDF
New coumarin glucopyranosides from roots of Angelica dahurica 被引量:3
2
作者 Ai-hong Zhao Xiu-wei Yang 《Chinese Herbal Medicines》 CAS 2018年第1期103-106,共4页
Objective: To investigate the chemical constituents from the roots of Angelica dahurica.Methods: The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as... Objective: To investigate the chemical constituents from the roots of Angelica dahurica.Methods: The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as well as semi-preparative reversed phase HPLC.The chemical structures were identified by spectral data.Results: Ten compounds were isolated and identified as xanthoarnol-3-O-β-d-glucopyranoside(1),angedahuricoside A(2),angedahuricoside B(3),isofraxidin-7-O-β-d-glucopyranoside(4),fraxidin-8-O-β-d-glucopyranoside(5),(-)-marmesinin(6),(2 S,3 R)-3-hydroxymarmesinin(7),hyuganoside V(8),daucosterol(9),and sucrose(10).Conclusion: Compounds 1 –3 are new ones and compounds 4 –6 and 8 are obtained from title plant for the first time. 展开更多
关键词 angedahuricoside A angedahuricoside B Angelica dahurica Benth. et Hook. f. ex Franch. et Sav coumarin glucopyranoside xanthoarnol-3-O-β-d-glucopyranoside
原文传递
Phenolic glucopyranosides from the Chinese mangrove plant Excoecaria agallocha L. 被引量:2
3
作者 李泳新 于霞 +3 位作者 于善江 马爱英 邓志威 林文翰 《Journal of Chinese Pharmaceutical Sciences》 CAS 2010年第4期256-259,共4页
Chemical examination of a Chinese mangrove plant Excoecaria agallocha L.led to the isolations of a new glucoside named l-(3,5-dimethoxy-4-hydroxybenzyl)-6-O-galloyl-l-O-β-D-glucopyranoside(1),together with 10 kno... Chemical examination of a Chinese mangrove plant Excoecaria agallocha L.led to the isolations of a new glucoside named l-(3,5-dimethoxy-4-hydroxybenzyl)-6-O-galloyl-l-O-β-D-glucopyranoside(1),together with 10 known glycosides including 3,5-dimethoxy-4-hydroxybenzyl-l-O-β-D-glucopyranoside(2),hydrangeifolin I(3),(2-methoxy-5-hydroxymethyl-phenyl) -l-O-β-D-(6-Ogalloyl) glucopyranoside(4),(3,5-dimethoxy-4-hydroxyphenyl)-l-O-β-D-(6-O-galloyl) glucopyranoside (5),3-methoxy-4-hydroxyphenyl l-O-β-D-(6-O-galloyl) glucopyranoside(6),3,4,5-trimethoxyphenyl-(6-O-galloyl)-O-β-D-glucopyranoside (7),koaburaside(8),koaburaside monomethyl ether(9),cuneatasides D(10),and(?)-isosyringin(11).Their structures were determined through the extensive spectroscopic analysis and comparison with the reported data in literature. Compounds 2-6,8-11 were isolated from the genus Excoecaria for the first time. 展开更多
关键词 Excoecaria agallocha Phenolic glucopyranoside Chemical components Mangrove plant
原文传递
STUDY ON C. D. SPECTRA OF SUBSTITUTED-C-PHENYL-D-GLUCOPYRANOSIDES
4
作者 岳保珍 张利民 +2 位作者 李慧莲 王动 蔡孟深 《Chinese Science Bulletin》 SCIE EI CAS 1990年第9期740-743,共4页
Ⅰ. INTRODUCTION C. D. curves can be applied to determination of the configuration of sugar and glycosides. Our study reports the C.D. data of several substituted-C-phenyl glucopyranosides, synthesized by the previous... Ⅰ. INTRODUCTION C. D. curves can be applied to determination of the configuration of sugar and glycosides. Our study reports the C.D. data of several substituted-C-phenyl glucopyranosides, synthesized by the previously described method. The crude product of Cglycosides was submitted to silica gel column chromatography or preparative thin layer chromatography to separate the anomers, whose configuration was determined by ~1HNMR. 展开更多
关键词 C-phenyl glucopyranosideS circular DICHROISM Cotton effect.
原文传递
无梗五加果化学成分的研究(英文) 被引量:30
5
作者 安琪 杨春娟 +3 位作者 宋洋 于凯 熊志立 李发美 《天然产物研究与开发》 CAS CSCD 2008年第5期765-769,共5页
从无梗五加(Acanthopanax sessiliflorus(Rupr.et Maxim.)Seem.)果70%乙醇提取物中分离鉴定了12个化合物。经波谱鉴定为东莨菪内酯(1),原儿茶酸甲酯(2),槲皮素(3),无梗五加苷B(4),金丝桃苷(5),(-)-pinoresinol-4,4′-di-O-β-D-glucopyr... 从无梗五加(Acanthopanax sessiliflorus(Rupr.et Maxim.)Seem.)果70%乙醇提取物中分离鉴定了12个化合物。经波谱鉴定为东莨菪内酯(1),原儿茶酸甲酯(2),槲皮素(3),无梗五加苷B(4),金丝桃苷(5),(-)-pinoresinol-4,4′-di-O-β-D-glucopyranoside(6),chiisanoside(7),22α-hydroxychiisanoside(8),niduloic acid(9),胡萝卜苷(10),东莨菪苷(11)和无梗五加苷D(12)。其中化合物9为新天然产物,化合物1,2,6和11是首次从五加科植物中分离得到,化合物3是首次从五加属植物中分离得到。 展开更多
关键词 五加属 元梗五加 niduloic ACID 东莨菪内酯 东莨菪苷 原儿茶酸甲酯 (-)-pinoresinol-4 4′-di-O-β-D- glucopyranoside 槲皮素
下载PDF
Two new glycosides from the seeds of Cassia obtusifolia 被引量:5
6
作者 Cun Zhang Gui Liu Li Yong Qing Xiao Li Li Zhen Pang 《Chinese Chemical Letters》 SCIE CAS CSCD 2009年第9期1097-1099,共3页
Two new glycosides, nor-rubrofusadn-6-O-β-D-(6'-O-acetyl)glucopyranoside (1) and 1-desmethylaurantio-obtusin-2-O-β-D- glucopyranoside (2) were isolated from the seeds of Cassia obtusifolia and their structure... Two new glycosides, nor-rubrofusadn-6-O-β-D-(6'-O-acetyl)glucopyranoside (1) and 1-desmethylaurantio-obtusin-2-O-β-D- glucopyranoside (2) were isolated from the seeds of Cassia obtusifolia and their structures were established by chemical and spectral evidences. 2009 Yong Qing Xiao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. 展开更多
关键词 Cassia obtusifolia Nor-rubrofusarin-6-O-β-D-(6'-O-acetyl)glucopyranoside 1-Desmethylaurantio-obtusin-2-O-β-D-glucopyranoside
下载PDF
竹叶兰的化学成分研究 被引量:12
7
作者 彭霞 何红平 +2 位作者 卯明霞 王跃虎 郝小江 《云南中医学院学报》 2008年第3期32-33,共2页
目的:研究竹叶兰的化学成分。方法:利用各种色谱技术进行分离纯化,根据各种波谱数据和文献数据对照进行结构鉴定。结果:分离鉴定两个化合物,分别为化合物3’,3’-二羟基-5’-甲氧基联苄(batatasinⅢ)(Ⅰ)、山奈酚-3-0-β-D-葡萄糖苷(kae... 目的:研究竹叶兰的化学成分。方法:利用各种色谱技术进行分离纯化,根据各种波谱数据和文献数据对照进行结构鉴定。结果:分离鉴定两个化合物,分别为化合物3’,3’-二羟基-5’-甲氧基联苄(batatasinⅢ)(Ⅰ)、山奈酚-3-0-β-D-葡萄糖苷(kaempferol-3-0-β-D-glucopyranoside)(Ⅱ),化合物。结论:两个化合物均为首次从竹叶兰中分离得到。 展开更多
关键词 竹叶兰 化学成分 化合物 batatasinⅢ kaempferol-3-0-β—D—glucopyranoside
下载PDF
A New Flavonol Glycoside from Anaphalis sinica Hance 被引量:2
8
作者 ZHOU Yi ZHANG Guo-lin +1 位作者 LI Bo-gang CHEN Yao-zu 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2001年第1期48-50,共3页
A new flavonol glycoside, 5,7,3,4 tetrahydroxy 3 methoxyflavonol 3 O β D glucopyranoside(1) was isolated along with quercetin(2), quercetin 3 O α L rhamnopyranoside(3), quercetin 3 O β D ... A new flavonol glycoside, 5,7,3,4 tetrahydroxy 3 methoxyflavonol 3 O β D glucopyranoside(1) was isolated along with quercetin(2), quercetin 3 O α L rhamnopyranoside(3), quercetin 3 O β D glucopyranoside(4) and kaempferol 3 O β D (6' O p coumaroyl) glucopyranoside(5) from Anaphalis sinica Hance. Their structures were determined on the basis of spectral data(MS, UV, IR, 1H and 13 C NMR). The structure of compound 1 was confirmed by X ray crystallographic analysis. 展开更多
关键词 Anaphalis sinica Hance Compositae 5 7 3' 4' Tetrahydroxy 3 methoxyflavonol 3' O β D glucopyranoside X ray crystallography
下载PDF
Two New Sterols from Bolbostemma paniculatum 被引量:1
9
作者 Wen Yong LIU, Wei Dong ZHANG, Hai Sheng CHEN, Zheng Ring GU, Ting Zhao LI, Wan Sheng CHENCollege of Pharmacy, Second Military Medical University, Shanghai 200433 《Chinese Chemical Letters》 SCIE CAS CSCD 2003年第10期1037-1040,共4页
Two new sterols were isolated from bulbs of Bolbostemma paniculatum (Maxim.) Franquet. Their structures were elucidated as stigmasta-7, 22, 25-triene-3-O-nonadecanoic acid ester (1) and stigmasta-7, 22, 25-triene-3-O-... Two new sterols were isolated from bulbs of Bolbostemma paniculatum (Maxim.) Franquet. Their structures were elucidated as stigmasta-7, 22, 25-triene-3-O-nonadecanoic acid ester (1) and stigmasta-7, 22, 25-triene-3-O-B-D- (6'-palmitoyl) glucopyranoside (2) by chemical and spectroscopic methods. 展开更多
关键词 Bolbostemma paniculatum STEROL stigmasta-7 22 25-triene-3-O-nonadecanoic acid ester stigmasta-7 22 25-triene-3-O-B-D- (6'-palmitoyl) glucopyranoside.
下载PDF
Bioguided Fractionation and Purification of Natural Bioactives Obtained from<i>Alpinia conchigera</i>Water Extract with Melanin Inhibition Activity
10
作者 Zanariah Binti Ujang Thavamanithevi Subramaniam +4 位作者 Mazita Md Diah Harmayumi Binti Wahid Badariah Binti Abdullah Ahmad Hazri Bin Abd Rashid David Appleton 《Journal of Biomaterials and Nanobiotechnology》 2013年第3期265-272,共8页
Crude extracts of Alpinia conchigera a species from the Malaysian Ginger (Zingiberaceae) family and its fractions obtained from various extraction methods were assayed for melanogenesis inhibition activity and cell vi... Crude extracts of Alpinia conchigera a species from the Malaysian Ginger (Zingiberaceae) family and its fractions obtained from various extraction methods were assayed for melanogenesis inhibition activity and cell viability. The crude extract obtained from the ethanolic extraction and the super critical fluid extraction did not exhibit significant melanin inhibition activity and was shown to be toxic to the melanocyte cells in comparison to the water extract. The crude aqueous extracts displayed melanin inhibition of 96.38 ± 1.60% and cell viability 109.90 ± 8.32% at a concentration of 500 μg/mL. Bioassay guided fractionation was performed on the water extracts to isolate the active compounds. The actives were identified as trans-cinnamaldehyde and chavicol glucopyranoside with both compound showing potent anti-melanogenesis activity. At 4.9 μg/ml, both trans-cinnamaldehyde and chavicol glucopyranoside gave 85% inhibition of melanin formation in vitro with 77% and 97% cell viability respectively. In comparison, kojic acid, a known skin lightening agent showed 90.0% inhibition at 100 μg/mL. The bioactive composition comprising the extract, active fraction, purified compounds or mixture thereof of Alpinia conchigera may be used for cosmetic and pharmaceutical applications, particularly for the purposes of reducing skin pigmentation. 展开更多
关键词 ALPINIA Conchigera Preparatory HPLC FRACTIONATION Chavicol glucopyranoside Trans Cinnamaldehyde Anti-Melanogenesis ACTIVITY
下载PDF
红花水提取物的化学成分研究 被引量:14
11
作者 赫军 陈钟 +3 位作者 杨桠楠 姜建双 冯子明 张培成 《中国药学杂志》 CAS CSCD 北大核心 2014年第6期455-458,共4页
目的对红花水提取物中的化学成分进行研究。方法通过大孔吸附树脂、Sephadex LH-20、反相HPLC等多种色谱进行分离纯化,根据理化性质和波谱数据进行鉴定。结果从红花水提物中分离得到了12个化合物,分别为(2E,8E)-12R—tetradeeadien... 目的对红花水提取物中的化学成分进行研究。方法通过大孔吸附树脂、Sephadex LH-20、反相HPLC等多种色谱进行分离纯化,根据理化性质和波谱数据进行鉴定。结果从红花水提物中分离得到了12个化合物,分别为(2E,8E)-12R—tetradeeadiene-4,6-diyne-1,12,14-triol(1),(8Z)-decaene-4,6-diyn-1—0-B-D—glucopyranoside(2),(8E)-decaene-4,6-diyn-1-0胡-D—glucopyranoside(3),(2S)-4’,5,6,7-四羟基二氢黄酮6-01B—D-吡喃葡萄糖苷(4),对羟基苯甲酸(5),异香草酸(6),dihydropha—seicacidmethylester.3-D移-D—glucoside(7),dihydrophaseicacidmethylester(8),对羟基苯甲醛(9),N,N'-dicoumaroyl-putrescine(10),4-(4'-羟基苯基)-丁-3-烯-2-酮(11),对羟基苯乙酮(12)。结论化合物1,3~4,6,8,10为首次从红花中分离得到,并首次报道化合物1的绝对构型及碳谱数据。 展开更多
关键词 红花 水提物 (2E 8E)-12R-tetradecadiene-4 6-diyne-1 12 14-triol (8Z)-decaene-4 6-diyn-1-O-β-D—glucopyranoside (8E)一decaene-4 6-diyn一1—0够一D—glucopyranoside 结构鉴定
原文传递
HPLC同时测定决明子中4种主要成分的含量 被引量:17
12
作者 苏会娟 王祝举 唐力英 《中国中药杂志》 CAS CSCD 北大核心 2011年第10期1327-1329,共3页
目的:建立HPLC同时测定决明子药材中蒽醌类和萘并吡喃酮类4种主要成分含量的方法,为决明子药材的质量控制提供依据。方法:采用Kromasil 100-5 C18色谱柱(4.6 mm×250 mm,5μm),流动相水-乙腈-四氢呋喃-冰醋酸(100∶23∶5∶1)... 目的:建立HPLC同时测定决明子药材中蒽醌类和萘并吡喃酮类4种主要成分含量的方法,为决明子药材的质量控制提供依据。方法:采用Kromasil 100-5 C18色谱柱(4.6 mm×250 mm,5μm),流动相水-乙腈-四氢呋喃-冰醋酸(100∶23∶5∶1)等度洗脱。检测波长278 nm,柱温30℃,流速1.0 mL.min-1。结果:4种成分达到了基线分离。红链霉素龙胆二糖苷,决明子苷,aurantio-obtusin-6-O-β-D-glucopyranoside以及决明子苷B线性范围为0.2741.37,0.1530.765,0.3021.51,0.0520.26μg,相关系数r均为0.999 9。平均加样回收率分别为100.9%(RSD 1.8%),101.2%(RSD 1.2%),99.40%(RSD 2.2%),100.5%(RSD 1.6%)。结论:建立了高效液相测定决明子中4种主要成分含量的方法,该方法精确,简便,可靠,重现性好,可用于决明子药材的质量控制。 展开更多
关键词 高效液相色谱法 决明子 红链霉素龙胆二糖苷 aurantio—obtusin-6-O-β-D—glucopyranoside 决明子苷 决明子苷 B 含量测定
原文传递
披针叶茴香果实的化学成分研究 被引量:8
13
作者 李慧娟 王丽霞 +3 位作者 刘孟奇 张雁冰 毕跃峰 柳继锋 《中国药学杂志》 CAS CSCD 北大核心 2014年第8期636-639,共4页
目的研究八角科(Illiciaceae)植物披针叶茴香(Illicium lanceolatum)果实的化学成分。方法应用硅胶、Sephadex LH-20、MCI等各种色谱技术进行分离纯化,根据化合物的理化常数和波谱数据鉴定其结构。结果从披针叶茴香果实的体积分数9... 目的研究八角科(Illiciaceae)植物披针叶茴香(Illicium lanceolatum)果实的化学成分。方法应用硅胶、Sephadex LH-20、MCI等各种色谱技术进行分离纯化,根据化合物的理化常数和波谱数据鉴定其结构。结果从披针叶茴香果实的体积分数95%乙醇提取物中分离得到12个化合物,通过渡谱数据和理化常数分别鉴定为2,4-dihydroxy—allylbenzene-2-O-β-D—glucopyranoside(1),(+)-儿茶素(2),槲皮素-3-O-β-L-鼠李糖苷(3),芦丁(4),异鼠李素-3-D-β-D-芸香糖苷(5),6-deoxy-1-hy—droxy neoanisatin(6),莽草毒素(7),icarisideE3(8),(75,8R)-urolignoside(9),对羟基苯甲酸(10),莽草酸(11),β-谷甾醇(12)。结论化合物1,4~6,8~10为首次从该植物中分离得到。 展开更多
关键词 八角属 披针叶茴香 2 4-dihydroxy—allylbenzene-2-O-β-D—glucopyranoside 芦丁 异鼠李素-3-O-β-D-芸香糖苷 6-deoxy-1-hydroxy neoanisatin
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部