Biostatistics (F analysis and Duncan's new multiple range test) combining with numerical and traditional taxonomy is used to report one new species, ( Isis minorbrachyblasta(I. m) ) as well as I. hippuris (I. h) a...Biostatistics (F analysis and Duncan's new multiple range test) combining with numerical and traditional taxonomy is used to report one new species, ( Isis minorbrachyblasta(I. m) ) as well as I. hippuris (I. h) and I. reticulata(I. r) from the China seas. The morphological characters of the spicules and other skeletal structures of each species are illustrated in de-tials with Scanning Electron Micrographs and compared with each other.展开更多
A new highly oxygenated guaiane lactone 5-epi-menverin C(1),along with four known compounds including one ses-quiterpene(2)and three steroids(3-5),were isolated from gorgonian Echinomuricea indomalaccensis which were ...A new highly oxygenated guaiane lactone 5-epi-menverin C(1),along with four known compounds including one ses-quiterpene(2)and three steroids(3-5),were isolated from gorgonian Echinomuricea indomalaccensis which were collected from the South China Sea.Through anlyzing the NMR data and comparing with other reported compounds,their structures were determined.The absolute configuration of compound 1 was determined by comparing its experimental ECD with that obtained by calculation.In a bioassay in vitro,5-epi-menverin C(1)displayed antiviral activity against the HSV-1 virus with an inhibition rate of 69.2%(c=25μmol L−1).展开更多
To investigate the chemical constituents of a South China Sea gorgonian Menella sp., the isolation of ingredients was performed by solvent extraction and repeated chromatography on silica gel, Sephadex LH-20 and prepa...To investigate the chemical constituents of a South China Sea gorgonian Menella sp., the isolation of ingredients was performed by solvent extraction and repeated chromatography on silica gel, Sephadex LH-20 and preparative TLC. The structures of isolated compounds were determined by spectroscopic analysis and comparison of 1H and 13C NMR data with those reported inliteratures. Three subergorane sesquiterpenoids and one suberosane sesquiterpenoid were isolated. Their structures were identified as subergorgic acid （1）, subergorgic acid methyl ester （2）, 2β-hydroxyl subergorgic acid methyl ester （3）, and suberosenol A （4）. All compounds were isolated from the genus Menella for the first time.展开更多
Seven new aromatic polyketides, communols A-G （1-7）, were isolated and identified from the fermentation broth of Penicillium commune 518, a marine-derived fungus associated with the Gorgonian, Muricella abnormalis. ...Seven new aromatic polyketides, communols A-G （1-7）, were isolated and identified from the fermentation broth of Penicillium commune 518, a marine-derived fungus associated with the Gorgonian, Muricella abnormalis. The new structures of 1-7 were determined by spectroscopic analysis and X-ray single crystal diffraction. Among them, communol D （4） was the first example of a naturally occurring aromatic polyketide with a sulfoxide group from marine thngi. Compounds 1, 6, and 7 all showed moderate antimicrobial activities against Escherichia coli and Enterobacter aerogenes with MIC values of 4.1/16.4, 6.4/25.8, and 23.8/23.8μmoloL^-1, respectively.展开更多
Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuene...Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.展开更多
文摘Biostatistics (F analysis and Duncan's new multiple range test) combining with numerical and traditional taxonomy is used to report one new species, ( Isis minorbrachyblasta(I. m) ) as well as I. hippuris (I. h) and I. reticulata(I. r) from the China seas. The morphological characters of the spicules and other skeletal structures of each species are illustrated in de-tials with Scanning Electron Micrographs and compared with each other.
基金supported by the National Key Research and Development Program of China (No. 2018YF C0310900)the National Natural Science Foundation of China (No. 41830535)+1 种基金the Fundamental Research Funds for the Central Universities of China (No. 201962002)the Taishan Scholars Program, China
文摘A new highly oxygenated guaiane lactone 5-epi-menverin C(1),along with four known compounds including one ses-quiterpene(2)and three steroids(3-5),were isolated from gorgonian Echinomuricea indomalaccensis which were collected from the South China Sea.Through anlyzing the NMR data and comparing with other reported compounds,their structures were determined.The absolute configuration of compound 1 was determined by comparing its experimental ECD with that obtained by calculation.In a bioassay in vitro,5-epi-menverin C(1)displayed antiviral activity against the HSV-1 virus with an inhibition rate of 69.2%(c=25μmol L−1).
基金Post-doctoral Science Foundation of China(Grant No.20080440784)Guangdong Province Natural Science Foundation(Grant No.9451030101003549)
文摘To investigate the chemical constituents of a South China Sea gorgonian Menella sp., the isolation of ingredients was performed by solvent extraction and repeated chromatography on silica gel, Sephadex LH-20 and preparative TLC. The structures of isolated compounds were determined by spectroscopic analysis and comparison of 1H and 13C NMR data with those reported inliteratures. Three subergorane sesquiterpenoids and one suberosane sesquiterpenoid were isolated. Their structures were identified as subergorgic acid （1）, subergorgic acid methyl ester （2）, 2β-hydroxyl subergorgic acid methyl ester （3）, and suberosenol A （4）. All compounds were isolated from the genus Menella for the first time.
文摘Seven new aromatic polyketides, communols A-G （1-7）, were isolated and identified from the fermentation broth of Penicillium commune 518, a marine-derived fungus associated with the Gorgonian, Muricella abnormalis. The new structures of 1-7 were determined by spectroscopic analysis and X-ray single crystal diffraction. Among them, communol D （4） was the first example of a naturally occurring aromatic polyketide with a sulfoxide group from marine thngi. Compounds 1, 6, and 7 all showed moderate antimicrobial activities against Escherichia coli and Enterobacter aerogenes with MIC values of 4.1/16.4, 6.4/25.8, and 23.8/23.8μmoloL^-1, respectively.
文摘Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.
