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Effectiveness of Post-Traumatic Growth Intervention to Promote Positive Post-Traumatic Traits in Chinese Breast Cancer Patients:A Randomized Controlled Trial
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作者 Cuirong Xu Han Yan +7 位作者 Dawei Xu Guanjie Chen Qian Xu Kunpeng Li Yehao Rui Zanmin Song Neeraj Gill Jing Sun 《International Journal of Mental Health Promotion》 2023年第10期1089-1102,共14页
Objective:The purpose of this study was to evaluate the effectiveness of post-traumatic growth(PTG)model-based intervention to improve positive psychological traits in Chinese breast cancer patients.Design:A randomize... Objective:The purpose of this study was to evaluate the effectiveness of post-traumatic growth(PTG)model-based intervention to improve positive psychological traits in Chinese breast cancer patients.Design:A randomized control trial of a psychological group intervention based on PTG model.Methods:The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264.A total of 92 patients with breast cancer were recruited.The participants were randomly assigned to the experimental group(n=46)and the control group(n=46).A six-session psychological group intervention based on PTG model was implemented in the experimental group,and a six-session health education was implemented in the control group.The outcomes weremeasured at baseline(pre-intervention),3 weeks,6 weeks after the intervention.The primary outcome was posttraumatic growth assessed by the Chinese version of the Post-Traumatic Growth Inventory(PTGI);Secondary outcomes included psychological resilience,family resilience,rumination,and self-disclosure.Results:A total of 87 patients with breast cancer completed this study,including 44 patients in the experimental group and 43 patients in the control group.There was no significant difference in baseline data of breast cancer patients between the two groups except for the treatment regimen(p>0.05).The two groups were compared after the intervention;the interaction effects between the total scores of posttraumatic growth,family resilience,and self-disclosure and the time term were statistically significant(p<0.05),indicating that the trend of change in total scores of post-traumatic growth,family resilience,and self-disclosure differed between the experimental and control groups over time,and the scores improved in the experimental group were significantly higher than those in the control group.The comparison of psychological resilience and total score of rumination at each time point was statistically significant(p<0.05),indicating that group intervention based on the PTG model could improve the psychological recovery ability and rumination level of the experimental group.Conclusion:The psychological group intervention based on the PTG model significantly improved post-traumatic growth,family resilience,and self-disclosure in patients with breast cancer.However,the impact on psychological resilience and rumination was relatively small.Long-term intervention is needed to further test the effect of the PTG model on psychological resilience and rumination. 展开更多
关键词 Post-traumatic growth psychological group intervention resilience RUMINaTION SELF-DISCLOSURE breast cancer Tech Science Press
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China Northern Rare Earth (Group)plans to building a number of world-class intelligent rare earth production demonstration lines
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《China Rare Earth Information》 2023年第3期27-27,共1页
Recently,the Department of Industry and Information Technology of Inner Mongolia Autonomous Region issued the Announcement on Publicity of Special Funds for the Development of Key Industries in 2023(the third batch),a... Recently,the Department of Industry and Information Technology of Inner Mongolia Autonomous Region issued the Announcement on Publicity of Special Funds for the Development of Key Industries in 2023(the third batch),and six enterprises,including China Northern Rare Earth(Group),were awarded as demonstration benchmark enterprises for industrial digital transformation in Inner Mongolia Autonomous Region. 展开更多
关键词 enterprises Earth group
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Growth performance and physiological parameters of the second generation selected and control groups of Pinctada martensii 被引量:10
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作者 DENG Yuewen YU Ziniu +2 位作者 DU Xiaodong WANG Qingheng FU Shao 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2011年第2期120-125,共6页
In May of 2007,the second generation selected (SS) and control (SC) groups of pearl oyster Pinctada martensii were established by selecting 10% breeders with the largest and mean shell length,respectively,from the... In May of 2007,the second generation selected (SS) and control (SC) groups of pearl oyster Pinctada martensii were established by selecting 10% breeders with the largest and mean shell length,respectively,from the first generation selected group.Growth performance of the SS and SC groups were compared on the basis of measurement data at Days 8,18,60,95,195 and 365.On Day 365,100 individuals (60.0–75.0 mm at shell length) were sampled from each group and then subjected to the experiment where physiological parameters such as filtrate rate,oxygen consumption and ammonia excretion were measured at 15,20,25 and 30°C.The results show that the SS group had significantly larger mean shell length and shell height than the SC group at Days 8,18,60,95,195 and 365 (P 0.05).The genetic gains at different ages varied from 6.0% to 17.0% for shell length and 5.7% to 14.6% for shell height,respectively.At 15,20,25 and 30 ° C,the SS groups had significantly larger filtrate rate than the SC group (P 0.05).At 15 and 25 °C,the differences in oxygen consumption rate between the SS and SC groups were not significant (P 0.05).At 20 and 30 °C,however,the oxygen consumption rate of the SS group was significantly larger than the SC group (P 0.05).At 15,20,25 and 30 °C,there were no significant differences in ammonia excretion rate between the SS and SC groups (P 0.05).The present results indicate that there existed considerable genetic variability in the base population and a further selection could be likely fruitful.Mass selection for faster growth might produce animals that had higher intake of metabolizable energy by virtue of faster filtrating behavior. 展开更多
关键词 Pinctada martensii the second generation selected group growth genetic gains physiological parameters
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Mechanism of Interaction between Entrepreneurial Spirit and Growth of Small and Medium Sized Private Enterprises
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作者 Peng XIE 《Asian Agricultural Research》 2016年第6期34-39,共6页
In the context of government appeal of " mass entrepreneurship and innovation",all areas launched the movement of " mass entrepreneurship" and " grassroots entrepreneurship". As parts of ... In the context of government appeal of " mass entrepreneurship and innovation",all areas launched the movement of " mass entrepreneurship" and " grassroots entrepreneurship". As parts of vitality of China's market economy,small and medium sized private enterprises become grassroots of market competition in talents,funds,and technologies. This paper combined three levels of entrepreneurial spirit and small and medium sized private enterprises,studied acting mechanism of entrepreneurial spirit,discussed competitive power of small and medium sized private enterprises,and recommended that small and medium sized private enterprises should cultivate core competitive power,adapt to external environment,and create external environment support,to realize sound development. 展开更多
关键词 ENTREPRENEURIaL SPIRIT Small and medium sized PRIVaTE enterprises ENTERPRISE growth
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Group planting of cherry (Prunus avium L.) fosters growth and tree quality is superior to conventional row planting in Germany
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作者 Somidh Saha 《Journal of Forestry Research》 SCIE CAS CSCD 2018年第4期1088-1099,共12页
Wild cherry trees produce high-quality timber and provide multiple ecosystem services. However, planting and tending cherry stands in conventional rows are too costly. Therefore, low density group planting was trialle... Wild cherry trees produce high-quality timber and provide multiple ecosystem services. However, planting and tending cherry stands in conventional rows are too costly. Therefore, low density group planting was trialled as an alternative to row planting. The mortality, growth, and quality of planted cherry trees were compared between the group and row planting. The influence of neighbourhood competition and light availability on growth and quality was studied. The group and row planting of cherry trees were established at a wind-thrown site in southwestern Germany in the year 2000. In group planting, five cherry seedlings and seven lime seedlings (Tilia cordata Mill.) were planted with a 1 x 1 m spacing. In total, 60 groups were planted per hectare with a 13 × 13 m spacing. In contrast, 3300 seedlings (2475 cherries and 825 limes) were planted per hectare in row planting with a 3 × 1 m spacing. Ten groups and plots (10 × 10 m) were randomly established in group and row planting stand, respectively. The survival rate, stability (height to diameter ratio), diameter, and height growth were significantly higher in group planting. In the group plantings,40.5% of cherry trees had straight stems and 13.5% had a monopodial crown compared with 15% with straight stems and 2% with a monopodial crown in row planting. The proportion of dominant cherry trees in canopy was 49% in groups compared with 22% in rows. The length of branch free bole was significantly higher in cherries planted in groups than those grown in rows. Intra- and interspecific competition reduced the growth and stability of cherry trees in row planting, but not in group planting. Light availability did not cause any significant effects on growth and quality between group and row planting. This first study on cherry group planting indicates that the survival rate, growth, and tree quality were higher in groups than in rows at this early development stage. The competition by naturally born seedlings was an important reason for the difference in performance between group and row planting. This study will encourage forest practitioners to establish more cherry group planting trials on multiple sites to test the effectiveness of this alternative technique as a tool of regeneration and restoration silviculture. 展开更多
关键词 group planting Tree growth Tree quality Interspecific competition Intraspecific competition Photosynthetically active photon flux density Total sitefactor
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Close Coupled Showerhead Reactors for the Growth of Group Ⅲ Nitrides
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作者 Thrush E J Kappers M +5 位作者 Considine L Mullins J T Saywell V Bentham F C Sharma N Humphreys C J 《发光学报》 EI CAS CSCD 北大核心 2001年第z1期103-106,共4页
The group Ⅲ nitrides are an important class of materials with aplications in UV and visible optoelectronics,high temperature electronics,cold cathodes and solar blind detectors.In recent years,with the realisation of... The group Ⅲ nitrides are an important class of materials with aplications in UV and visible optoelectronics,high temperature electronics,cold cathodes and solar blind detectors.In recent years,with the realisation of nitride based LEDs,the use of GaN IED has the potential to compete with 1raditional filament and discharge lamps,for the provision of white lighting,and there has been an explosion of interest in the MOCVD growth of GaN based materials with an increasing focus on large area multiwafer reactors and wafer uniforrmity.This paper will review the design philosophy and characteristics of close-coupled showerhead reactors,relating these to the requirements of group Ⅲ-nitride growth,and will present a selection of data resulting from the operation of such equipment.These results suggest that the close coupled showerhead style of reactor is very suitable for the growth of GaN based structures in both research and production environments. 展开更多
关键词 MOCVD close coupled showerhead reactor growth of groupⅢnitrides
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Creativity of the Entrepreneur, Intrapreneurship, and the Growth of Small and Medium-Sized Enterprises: Evidence from China
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作者 Jasna Auer Antoncic Bostj an Antoncic Zhaoyang Li 《Chinese Business Review》 2018年第7期336-341,共6页
Creativity is an element of the personality of entrepreneurs which can be important for the foundation, advance, and business performance of small and medium-sized enterprises (SMEs). Intrapreneurship can be develop... Creativity is an element of the personality of entrepreneurs which can be important for the foundation, advance, and business performance of small and medium-sized enterprises (SMEs). Intrapreneurship can be developed in small and medium-sized enterprises where entrepreneurs have a sufficient level of creativity and it can influence the growth of enterprises. Hypotheses are specified and empirically tested based on responses to a structured questionnaire on a sample of small and medium-sized enterprises from China. The research results indicate positive relationships between the creativity of the entrepreneur and intrapreneurship and growth of the enterprise. 展开更多
关键词 CREaTIVITY ENTREPRENEUR INTRaPRENEURSHIP growth small and medium-sized enterprises (SMEs) China
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The Importance of Investments on Small- and Medium-Sized Enterprises (SMEs) Growth: The Case of Kosovo
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作者 Skender Ahmeti Justina Shiroka-Pula Venet Shala 《Journal of Modern Accounting and Auditing》 2013年第7期953-960,共8页
The small- and medium-sized enterprises (SMEs) are crucial to economic growth, especially in post-socialist transitional countries or new emerging market economies. The development of SMEs depends on the ability of ... The small- and medium-sized enterprises (SMEs) are crucial to economic growth, especially in post-socialist transitional countries or new emerging market economies. The development of SMEs depends on the ability of those firms to invest and grow. Based upon an SME survey conducted by Riinvest Institute at the end of 2010, this paper seeks to provide answers on determinants of SMEs to invest in Kosovo, based on an econometric model which identifies the key determinants of SMEs' investment. The econometric evidence suggests a positive relationship between investment and the size and age of the company. Also, the decision of the firm to invest depends on the future business plans; if entrepreneurs have optimistic views about the future of the business, this encourages them to invest. The manufacturing and trade sectors invest more, so do exporting firms, which may be because of bigger market opportunities. Access to external sources of finance is another significant determinant of investment, suggesting that firms which gained credit invested more than other firms in the sample. 展开更多
关键词 small- and medium-sized enterprises (SMEs) INVESTMENT growth econometric model KOSOVO
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TO Be Involved in Global Competitionis the Way to Development for Enterprises─Introduction of Wanxiang Group Company
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《China's Foreign Trade》 2000年第6期41-42,共2页
关键词 BE Introduction of Wanxiang group Company TO Be Involved in Global Competitionis the Way to Development for enterprises
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Analysis on Characters and Growth Factors of academicians of Agriculture Faculty of Chinese Academy of Engineering 被引量:2
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作者 邓文 单杨 《Agricultural Science & Technology》 CAS 2015年第12期2664-2669,共6页
The research analyzed birthplace, work site and Work unit, discipline, agri- cultural product variety, current age, and selected age, as well as internal and exter- nal factors for growth, which providers references f... The research analyzed birthplace, work site and Work unit, discipline, agri- cultural product variety, current age, and selected age, as well as internal and exter- nal factors for growth, which providers references for exploring development of high- level agricultural S&T talents and formulation of relevant policies. 展开更多
关键词 Chinese academy of Engineering Faculty of agriculture group charac- teristics growth factors
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Analysis on Polymorphisms of GHR Gene in Improved Hybrid Yellow Cattle Groups from Liupan Mountain Area in Ningxia 被引量:1
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作者 张春珍 李聚才 +1 位作者 杨易 于建勇 《Agricultural Science & Technology》 CAS 2011年第3期413-416,共4页
[Objective] The paper aimed to analyze the polymorphism of the growth hormone receptor (GHR) in improved hybrid yellow cattle group from Liupan Mountain area in Ningxia Autonomous Region,so as to provide technologic... [Objective] The paper aimed to analyze the polymorphism of the growth hormone receptor (GHR) in improved hybrid yellow cattle group from Liupan Mountain area in Ningxia Autonomous Region,so as to provide technological basis for hybrid improvement. [Method] Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) technology was carried out to examine polymorphisms of GHR gene of 70 individuals. [Result] The target fragment of 338 bp was amplified. The PCR product digested by restriction enzyme Alu I showed polymorphisms. The frequencies of the two genotypes (AA,BB) were 75.71% (53 individuals) and 24.29% (17 individuals),respectively. [Conclusion] Two genotypes of GHR gene were detected in improved hybrid yellow cattle groups from Liupan Mountain area in Ningxia. 展开更多
关键词 Hybrid yellow cattle group growth hormone receptor gene POLYMORPHISM
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Barriers to the Growth of Small and Medium Scale Construction Enterprises in Ghana
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作者 Simon Ofori Ametepey Emmanuel Yaw Frempong Jnr John Edward Cobbina 《Open Journal of Civil Engineering》 2022年第1期38-55,共18页
The construction industry in most developing economies is dominated heavily by small and medium scale enterprises. These construction enterprises need to thrive in an extremely competitive business environment. Conver... The construction industry in most developing economies is dominated heavily by small and medium scale enterprises. These construction enterprises need to thrive in an extremely competitive business environment. Conversely, most of these small and medium scale construction enterprises (SMSCE) are fraught with a plethora of barriers that inhibit and threaten their growth and survival. This research sought to evaluate the critical barriers that affect the growth of SMSCEs in the Ghanaian Construction Industry. The quantitative research method was adopted using a structured questionnaire with variables that were identified through a comprehensive literature review. The survey questionnaire was administered to 400 respondents comprising 250 SMSCEs, 100 Local Authority Engineers, and 50 Consultants to elicit data based on the identified variables. The major findings established by the study as barriers to the growth of SMSCEs in Ghana are largely structured as financial/fiscal barriers, business development barriers, technical/technological barriers, corruption barriers, knowledge management barriers, project acquisition barriers. A guiding framework should be developed based on the barriers identified to aid the growth and survival of SMSCEs in Ghana. 展开更多
关键词 Barriers Business growth Business Survival Developing Countries Small and Medium Scale Enterprise SME
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Synergistic“Anchor‑Capture”Enabled by Amino and Carboxyl for Constructing Robust Interface of Zn Anode 被引量:5
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作者 Zhen Luo Yufan Xia +9 位作者 Shuang Chen Xingxing Wu Ran Zeng Xuan Zhang Hongge Pan Mi Yan Tingting Shi Kai Tao Ben Bin Xu Yinzhu Jiang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2023年第11期265-280,共16页
While the rechargeable aqueous zinc-ion batteries(AZIBs)have been recognized as one of the most viable batteries for scale-up application,the instability on Zn anode–electrolyte interface bottleneck the further devel... While the rechargeable aqueous zinc-ion batteries(AZIBs)have been recognized as one of the most viable batteries for scale-up application,the instability on Zn anode–electrolyte interface bottleneck the further development dramatically.Herein,we utilize the amino acid glycine(Gly)as an electrolyte additive to stabilize the Zn anode–electrolyte interface.The unique interfacial chemistry is facilitated by the synergistic“anchor-capture”effect of polar groups in Gly molecule,manifested by simultaneously coupling the amino to anchor on the surface of Zn anode and the carboxyl to capture Zn^(2+)in the local region.As such,this robust anode–electrolyte interface inhibits the disordered migration of Zn^(2+),and effectively suppresses both side reactions and dendrite growth.The reversibility of Zn anode achieves a significant improvement with an average Coulombic efficiency of 99.22%at 1 mA cm^(−2)and 0.5 mAh cm^(−2)over 500 cycles.Even at a high Zn utilization rate(depth of discharge,DODZn)of 68%,a steady cycle life up to 200 h is obtained for ultrathin Zn foils(20μm).The superior rate capability and long-term cycle stability of Zn–MnO_(2)full cells further prove the effectiveness of Gly in stabilizing Zn anode.This work sheds light on additive designing from the specific roles of polar groups for AZIBs. 展开更多
关键词 Zn anode–electrolyte interface Polar groups Synergistic“anchor-capture”effect Side reactions Dendrite growth
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ATTEMPTS AND EXPLORATIONS TO ENTER THE MARKET: THE GROWTH AND DEVELOPMENT OF HIGH- AND NEW-TECH ENTERPRISES
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作者 Li Zhijie and Bai Jianyuan(Bureau of High-tech Enterprises, the CAS) 《Bulletin of the Chinese Academy of Sciences》 1995年第2期147-151,共5页
In 1984, under the guideline laid down by the Communist Party of China, "economic construction must rely on science and technology, and science and technology must be geared to serve economic construction", ... In 1984, under the guideline laid down by the Communist Party of China, "economic construction must rely on science and technology, and science and technology must be geared to serve economic construction", the CAS began to encourage enthusiastically its scientific and technical personnel to run high-and new tech enterprises.At present,there are more than 500 S&T enterprises at the Academy,including five (group)corporations directly under the jurisdiction of the Academy, 21 co-operation enterprises,40 or so 展开更多
关键词 THE growth aND DEVELOPMENT of HIGH aND NEW-TECH enterprises aTTEMPTS aND EXPLORaTIONS TO ENTER THE MaRKET
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Can environmental sustainability be decoupled from economic growth? Empirical evidence from Eastern Europe using the common correlated effect mean group test 被引量:1
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作者 Kwaku ADDAI Berna SERENER Dervis KIRIKKALELI 《Regional Sustainability》 2023年第1期68-80,共13页
The European Union(EU) and Organisation for Economic Co-operation and Development(OECD) aim to develop long-term policies for their respective member countries. Having observed increasing dangers to the environment po... The European Union(EU) and Organisation for Economic Co-operation and Development(OECD) aim to develop long-term policies for their respective member countries. Having observed increasing dangers to the environment posed by rising economic growth, they are seeking pathways to enable policy action on economic growth and environmental sustainability. Given the facts in theoretical and empirical studies, this study assessed the validity of the decoupling hypothesis by investigating asymmetricity in the relationship between environmental sustainability and economic growth in nine Eastern European countries from 1998 to 2017 using the cross-section augmented Dickey-Fuller(CADF) unit root, panel corrected standard error(PCSE), common correlated effect mean group(CCEMG), and Dumitrescu Hurlin causality approaches. Both population growth and drinking water are used as controlled variables. The outcomes establish strong cointegration among all the variables of interest. According to the results of CCEMG test, economic growth exerts short-term environmental degradation but has long-term environmental benefits in Eastern Europe;and population growth and drinking water exert a positive effect on environmental sustainability in both the short-and long-run. The results of Dumitrescu Hurlin causality test indicate that environmental sustainability is unidirectionally affected by economic growth. Based on these outcomes, we suggest the following policies:(1) the EU and OECD should implement member-targeted policies on economic growth and fossil-fuel use towards regulating industrial pollution, water use, and population control;and(2) the EU and OECD member countries should invest in environmental technologies through green research and development(R&D) to transform their dirty industrial processes and ensure productive energy use. 展开更多
关键词 Economic growth Environment sustainability Decoupling Carbon emissions Eastern Europe Common correlated effect mean group(CCEMG)test Econometrics Population growth
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MODELS OF THE SPATIAL EVOLUTION OF MULTI-PLANT ENTERPRISES 被引量:1
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作者 费洪平 《Chinese Geographical Science》 SCIE CSCD 1994年第2期134-147,共14页
Since the 1970s, the studies on the geography of enterprise have become increasingly concerned with the spatial evolution of an enterprises in the West developed countries. However, little attention has so far been g... Since the 1970s, the studies on the geography of enterprise have become increasingly concerned with the spatial evolution of an enterprises in the West developed countries. However, little attention has so far been given to the spatial evolution of an enterprise in China. With China's ongoing economy and political reforms, a number of fundamental changes of enterprise behavior have occurred. These changes have certainly important influences on the evolution of industrial location. Therefore, there is a need for examining the spatial evolution of an enterprise in China. The purpose of the paper is to review the mapjor models of both the growth,and associated spatial evolution of an enterprise, with an illustrative case study of the HeaVy Automobile Enterprise Group of China. The paper is organized by three parts. The first examines the spoilal groWth and location adjustment of multi-plant enterprise. The second reviews mapjor models of the spatial evolution of an enterprise. And the third analyzes the spatial evolution, over a period of time, of a representative sample of the Heavy Automobile Enterprise Group of China, and illustrates the findings with case studies. It is suggested that the models of spatial evolution of an enterprise would provide more evidence about micro-mechanism for evolution of micro- regional economic systems. 展开更多
关键词 multi-plant enterprises ENTERPRISE groupS SPaTIaL evolution of an ENTERPRISE SPaTIaL growth location adjustment
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Stability of growth periods traits for soybean cultivars across multiple locations 被引量:2
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作者 WANG Xiao-bo LIU Zhang-xiong +12 位作者 YANG Chun-yan XU ran LU Wei-guo ZHANG Li-feng WANG Qian WEI Su-hong YANG Chun-ming WANG Hui-cai WANG Rui-zhen ZHOU Rong CHEN Huai-zhu CHANG Ru-zhen QIU Li-juan 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2016年第5期963-972,共10页
The growth periods(GPs, from planting/emergence to reproductive stage 8(R8) of soybean cultivars vary in different ecological regions, especially in China with a very complex soybean cropping system. In this study,... The growth periods(GPs, from planting/emergence to reproductive stage 8(R8) of soybean cultivars vary in different ecological regions, especially in China with a very complex soybean cropping system. In this study, a 3-yr experimental study was undertaken in three geographical locations of China from 2008 to 2010, including the Northeast(40.66-45.85°N), Huang-Huai(34.75-38.04°N) and southern(22.82-30.60°N) eco-regions with about 250 accessions in each region to clarify the classification of maturity group(MG) and identify the cultivars with stable GP to increase the knowledge about the GP distribution of soybean cultivars in China. GPs of soybean cultivars in different eco-regions were significant different with a gradual decrease from 115-125 d in the Northeast part to the 85-100 d in the southern part of China. The geographical location was the major factor for GP of cultivars from the Northeast, while the year of planting was the major factor affecting the stability of GPs in Huang-Huai summer and southern summer soybean. AMMI2(additive main effects and multiplicativeinteraction)-Biplot analysis showed that the GPs of soybean cultivars from the Northeast eco-region have a comparatively satisfactory environmental stability. Moreover, soybean cultivars with moderate GP/MG and stable environment adaptability in different eco-regions were identified based on the linear regression and AMMI analysis, which was important for the accurate classification of soybean MGs in future. Taken together, our results reflected the genetic diversity, geographical distribution and environmental stability of the Chinese soybean GP trait. Soybean cultivars with stable GP for various Chinese eco-regions would be beneficial for Chinese soybean genetic improvement, varietal introduction, exchange, and soybean breeding program for wide adaptability. 展开更多
关键词 SOYBEaN growth periods maturity group environmental stability
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Topical delivery of nerve growth factor for treatment of ocular and brain disorders 被引量:13
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作者 Gemma Eftimiadi Marzia Soligo +3 位作者 Luigi Manni Daniela Di Giuda Maria Lucia Calcagni Antonio Chiaretti 《Neural Regeneration Research》 SCIE CAS CSCD 2021年第9期1740-1750,共11页
Neurotrophins are a family of proteins that support neuronal proliferation, survival, and differentiation in the central and peripheral nervous systems, and are regulators of neuronal plasticity. Nerve growth factor i... Neurotrophins are a family of proteins that support neuronal proliferation, survival, and differentiation in the central and peripheral nervous systems, and are regulators of neuronal plasticity. Nerve growth factor is one of the best-described neurotrophins and has advanced to clinical trials for treatment of ocular and brain diseases due to its trophic and regenerative properties. Prior trials over the past few decades have produced conflicting results, which have principally been ascribed to adverse effects of systemic nerve growth factor administration, together with poor penetrance of the blood-brain barrier that impairs drug delivery. Contrastingly, recent studies have revealed that topical ocular and intranasal nerve growth factor administration are safe and effective, suggesting that topical nerve growth factor delivery is a potential alternative to both systemic and invasive intracerebral delivery. The therapeutic effects of local nerve growth factor delivery have been extensively investigated for different ophthalmic diseases, including neurotrophic keratitis, glaucoma, retinitis pigmentosa, and dry eye disease. Further, promising pharmacologic effects were reported in an optic glioma model, which indicated that topically administered nerve growth factor diffused far beyond where it was topically applied. These findings support the therapeutic potential of delivering topical nerve growth factor preparations intranasally for acquired and degenerative brain disorders. Preliminary clinical findings in both traumatic and non-traumatic acquired brain injuries are encouraging, especially in pediatric patients, and clinical trials are ongoing. The present review will focus on the therapeutic effects of both ocular and intranasal nerve growth factor delivery for diseases of the brain and eye. 展开更多
关键词 alzheimer's disease eye drops group B streptococcus meningitis glioma intranasal delivery neurotrophic keratitis nerve growth factor proNGF stroke traumatic brain injury
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Temporal and spatial distribution of phytoplankton functional groups and role of environment factors in a deep subtropical reservoir 被引量:5
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作者 LI Lei LI Qiuhua +3 位作者 CHEN Jing'an WANG Jingfu JIAO Shulin CHEN Fengfeng 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2018年第3期761-771,共11页
Phytoplankton and environment factors were investigated in 2015 and phytoplankton functional groups were used to understand their temporal and spatial distribution and their driving factors in Wanfeng Reservoir. Seven... Phytoplankton and environment factors were investigated in 2015 and phytoplankton functional groups were used to understand their temporal and spatial distribution and their driving factors in Wanfeng Reservoir. Seventeen functional groups(B, D, E, F, G, J, Lo, MP, P, S1, T, W1, W2, X1, X2, Xph, Y) were identified based on 34 species. The dominant groups were: J/B/P/D in dry season, X1/J/Xph/G/T in normal season and J in flood season. Phytoplankton abundance ranged from 5.33×10~4 cells/L to 3.65×10~7 cells/L, with the highest value occurring in flood season and lowest in dry season. The vertical profi le of dominant groups showed little differentiation except for P, which dominated surface layers over 20 m as a result of mixing water masses and higher transparency during dry season. However, the surface waters presented higher values of phytoplankton abundance than other layers, possibly because of greater irradiance. The significant explaining variables and their ability to describe the spatial distribution of the phytoplankton community in RDA diff ered seasonally as follows: dry season, NH4-N, NO_3-N, NO_2-N, TN:TP ratio and transparency(SD); normal season, temperature(WT), water depth, TN, NH4-N and NO_3-N; flood season, WT, water depth, NO_3-N and NO_2-N. Furthermore, nitrogen, water temperature, SD and water depth were significant variables explaining the variance of phytoplankton communities when datasets included all samples. The results indicated that water physical conditions and hydrology were important in phytoplankton community dynamics, and nitrogen was more important than phosphorus in modifying phytoplankton communities. Seasonal differences in the relationship between the environment and phytoplankton community should be considered in water quality management. 展开更多
关键词 phytoplankton functional groups temporal and spatial distribution growth strategy driving factors Wanfeng Reservoir
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Compositional Distribution and Growth Mode of Garnet Porphyroblasts during Deformation and Metamorphism 被引量:1
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作者 ZHAOGuiping LIUShuwen LIUXiaohan 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2004年第1期186-190,共5页
Although porphyroblast microstructures play an important role in structural and metamorphic studies, there are still controversies in the interpretation. The focus is how porphyroblasts grow during deformation and met... Although porphyroblast microstructures play an important role in structural and metamorphic studies, there are still controversies in the interpretation. The focus is how porphyroblasts grow during deformation and metamorphism. In this paper, we introduce a new approach, the Synchrotron Radiation X-Ray Fluorescence, to a hemi-quantitative interpretation of the growth mode of porphyroblasts. The analysis was done at the Beijing Synchrotron Radiation Facility. The specimens were sampled from metapelite of the Baoyintu Group, northern Urad Middle Banner, Inner Mongolia. The new method is successful for determining the microscopic distribution of trace elements in porphybroblasts. The results support the theory of deformation partition, which has been brought forth by Bell and his colleagues, and demonstrate the existence of porphyroblast growth phases and the growth mode of porphyroblasts by hemi-quantitative mineral chemical analysis. The porphyroblast grows stage by stage in the manner of the distribution of a roseleaf and is controlled by deformation. We call the growth stage of porphyroblast a growth phase. 展开更多
关键词 Synchrotron Radiation X-ray Fluorescence analysis deformation partition PORPHYROBLaST growth phase Baoyintu group
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