A facile, efficient synthesis of 3-（guaiazulen-l-yl）succinimides was developed by Michael-type addition of guaiazulene to maleimides in the presence of p-toluenesulfonic acid under mild reaction conditions.
An efficient and mild synthesis of 2-（guaiazulen-l-yl）furans, starting from easily accessible 1-（3-aryl-2- cyanopropenoyl）guaiazulenes, tributylphosphine and acyl chlorides, is described. The strategy employs the ...An efficient and mild synthesis of 2-（guaiazulen-l-yl）furans, starting from easily accessible 1-（3-aryl-2- cyanopropenoyl）guaiazulenes, tributylphosphine and acyl chlorides, is described. The strategy employs the intramolecular Wittig protocol as a key step to append the crucial furan ring, leading to the highly functional furans in good yields.展开更多
基金the Foundation of Innovation Team Project of Liaoning Education Department(No.2008T001) for financial support
文摘A facile, efficient synthesis of 3-（guaiazulen-l-yl）succinimides was developed by Michael-type addition of guaiazulene to maleimides in the presence of p-toluenesulfonic acid under mild reaction conditions.
基金the Science and Technology Department of Liaoning Province(No.2011220022)the Innovation Talent Program of Heilongjiang University of Chinese Medicine for financial support
文摘An efficient and mild synthesis of 2-（guaiazulen-l-yl）furans, starting from easily accessible 1-（3-aryl-2- cyanopropenoyl）guaiazulenes, tributylphosphine and acyl chlorides, is described. The strategy employs the intramolecular Wittig protocol as a key step to append the crucial furan ring, leading to the highly functional furans in good yields.
