Identifying each process and their constraint relations from the complex wiring harness drawings quickly and accurately is the basis for formulating process routes. According to the knowledge of automotive wiring harn...Identifying each process and their constraint relations from the complex wiring harness drawings quickly and accurately is the basis for formulating process routes. According to the knowledge of automotive wiring harness and the characteristics of wiring harness components, we established the model of wiring harness graph. Then we research the algorithm of identifying technology processes automatically, finally we describe the relationships between processes by introducing the constraint matrix, which is in or- der to lay a good foundation for harness process planning and production scheduling.展开更多
Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue re...Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.展开更多
The dry-hot valleys (DHV) are located mainly in the deeply incised v alleys along the upper streams of several international and domestically rivers, like Yangtz, Zhu, Lanchang, Hong, and Nu rivers. This paper briefl...The dry-hot valleys (DHV) are located mainly in the deeply incised v alleys along the upper streams of several international and domestically rivers, like Yangtz, Zhu, Lanchang, Hong, and Nu rivers. This paper briefly described t he reasons of formation of DHV from view of climate and geographical conditions, and by referring to great deal of documents, analyzed the historical case and p resent status of the vegetations in DHV. The environment in DHV is facing the se rious vulnerable period in the history due to its nature situation of half-year dry period, fragile geological structure and shallow soil, and its social situat ion of over dense population and over farming. The primary vegetation is broad l eaf forest and it was denuded in the history. The current local vegetation is th e degraded secondary vegetation: savanna and succulent thorny shrub. Since the e nvironmental situation in valley influenced directly the water body of river, th e soil erosion control and re-vegetation in DHV is the most urgent task in the p rocess of environmental harness along the rivers. Quite a few pilot research pro jects have been carried out.on demonstrating new silviculture techniques for re- vegetation in DHV, but there still exist great difficulties in carrying out larg e-scale afforestation engineering.展开更多
基金Supported by Chinese national Science Foundation (61070124)the Fundamental Research Funds for the Central Universities (2012HGBZ0195)
文摘Identifying each process and their constraint relations from the complex wiring harness drawings quickly and accurately is the basis for formulating process routes. According to the knowledge of automotive wiring harness and the characteristics of wiring harness components, we established the model of wiring harness graph. Then we research the algorithm of identifying technology processes automatically, finally we describe the relationships between processes by introducing the constraint matrix, which is in or- der to lay a good foundation for harness process planning and production scheduling.
文摘Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.
基金National Natural Science Foundation of China(Nos.62371118,6210020445 and 61901104)Natural Science Foundation of Shanghai,China(Nos.21ZR1446900 and 21511100102)Science and Technology Research Project of Shanghai Songjiang District,China(No.20SJKJGG4C)。
基金the Fund of Leading Scientists in Yun nan and the Yunnan Provincial Fund for Natural Science Research (Grant No. 98C06 0M and 98
文摘The dry-hot valleys (DHV) are located mainly in the deeply incised v alleys along the upper streams of several international and domestically rivers, like Yangtz, Zhu, Lanchang, Hong, and Nu rivers. This paper briefly described t he reasons of formation of DHV from view of climate and geographical conditions, and by referring to great deal of documents, analyzed the historical case and p resent status of the vegetations in DHV. The environment in DHV is facing the se rious vulnerable period in the history due to its nature situation of half-year dry period, fragile geological structure and shallow soil, and its social situat ion of over dense population and over farming. The primary vegetation is broad l eaf forest and it was denuded in the history. The current local vegetation is th e degraded secondary vegetation: savanna and succulent thorny shrub. Since the e nvironmental situation in valley influenced directly the water body of river, th e soil erosion control and re-vegetation in DHV is the most urgent task in the p rocess of environmental harness along the rivers. Quite a few pilot research pro jects have been carried out.on demonstrating new silviculture techniques for re- vegetation in DHV, but there still exist great difficulties in carrying out larg e-scale afforestation engineering.
