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Healing Time
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作者 LI LI 《Beijing Review》 2009年第29期16-16,共1页
Xinjiang’s local governments now focus on treating the injured and rejuvenating local tourism The capital of Xinjiang Uygur Auto- nomous Region, Urumqi, is getting back to normal a week after July 5’s — fatal riot,... Xinjiang’s local governments now focus on treating the injured and rejuvenating local tourism The capital of Xinjiang Uygur Auto- nomous Region, Urumqi, is getting back to normal a week after July 5’s — fatal riot, despite sporadic tension. 展开更多
关键词 healing time
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重组牛碱性成纤维细胞生长因子治疗慢性鼓膜穿孔的相关机制及临床研究 被引量:7
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作者 陈如如 项海杰 +1 位作者 张初琴 陈波蓓 《中国耳鼻咽喉头颈外科》 CSCD 2022年第8期527-529,515,共4页
目的 观察重组牛碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)在慢性鼓膜穿孔愈合过程中所起的作用,探讨bFGF的作用机制、疗效及对中耳功能的影响。方法 收集温州医科大学附属第二医院门诊就诊的慢性鼓膜穿孔患者39例... 目的 观察重组牛碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)在慢性鼓膜穿孔愈合过程中所起的作用,探讨bFGF的作用机制、疗效及对中耳功能的影响。方法 收集温州医科大学附属第二医院门诊就诊的慢性鼓膜穿孔患者39例,并根据穿孔原因分为慢性外伤性鼓膜穿孔组20例和中耳炎引起的慢性鼓膜穿孔组19例。两组分别根据不同的治疗方法随机再分为2组:第1组为自然愈合对照组,第2组为bFGF治疗组。首诊时,第1组予碘伏清洁患耳外耳道后行耳内镜、纯音听力、声导抗检查,并嘱患者保持外耳道干燥,并定期观察鼓膜愈合情况。第2组先予碘伏清洁患耳后行耳内镜、纯音听力、声导抗检查,予bFGF制剂(贝复舒)滴耳,1次/d,每隔1周以上复诊,观察患耳鼓膜愈合情况及愈合时间,有无并发症等情况。结果外伤引起的慢性穿孔中,bFGF治疗组、自然愈合对照组比较,在愈合时间上,干预组穿孔完全愈合时间较对照组明显缩短,差异有显著统计学意义(P<0.01)。在愈合率上,干预组比对照组明显提高,差异有显著统计学意义(P<0.01)。中耳炎引起的鼓膜穿孔中的bFGF治疗组与保守治疗组比较,bFGF治疗组的愈合率为27.3%,对照组均未愈合,差异无统计学意义(P>0.05)。结论 单独应用bFGF可明显促进慢性外伤性鼓膜穿孔的愈合,可提高穿孔的愈合率;bFGF亦可缩短慢性外伤性鼓膜穿孔的愈合时间;单独应用bFGF能促进中耳炎引起的慢性鼓膜小穿孔的愈合,对于中等或大穿孔可以缩小穿孔面积;中耳炎引起的慢性鼓膜穿孔联合使用bFGF和明胶海绵可能起到更大的作用效果。 展开更多
关键词 鼓膜穿孔(Tympanic Membrane Perforatio) 成纤维细胞生长因子(Fibroblast Growth Factors) 重组牛碱性成纤维细胞生长因子(basic fibroblast growth factor) 愈合率(healing rate) 愈合时间(healing time)
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The association between vitamin D levels and burn factors in different burn types 被引量:1
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作者 Yoon Soo Cho Cheong Hoon Seo +1 位作者 So Young Joo Suk Hoon Ohn 《Burns & Trauma》 SCIE 2020年第1期285-292,共8页
Background:Patients with burns present with different clinical features depending on the types of burn injury and burn patients with lower levels of vitamin D have worse prognoses and more complications.The study aims... Background:Patients with burns present with different clinical features depending on the types of burn injury and burn patients with lower levels of vitamin D have worse prognoses and more complications.The study aims to investigate the association between vitamin D levels and burn factors according to each burn type in relation to early intensive rehabilitation therapy initiated for inpatients with burns.Methods:In this retrospective study,we enrolled 757 of 1716 inpatients who underwent rehabilitative therapy between May 2013 and April 2017.Burn types were divided into flame burn,electrical burn and other burns,including scalding,contact and chemical burns.Age,burned body surface area(BSA),wound healing time(WHT),length of hospital stay(LOS)and body mass index were analysed between vitamin D deficient and non-deficient patient groups using Student’s ttests,or Mann-Whitney U test and among three burn types using one-way analysis of variance(ANOVA)or Kruskal-Wallis one-way ANOVA.The relationship between vitamin D levels and burn factors was evaluated using Pearson’s or Spearman’s correlation coefficient tests,and multiple linear regression analysis in different burn groups.Results:In total,88.9%patients were vitamin D deficient,and these patients had a larger burned BSA(p=0.015)and longer WHT and LOS(all p<0.001)than non-deficient patients.Burned BSA,WHT and vitamin D levels showed significant differences in their mean values according to three burn types(all p<0.001).WHT was a communal factor significantly associated with vitamin D levels in all three burn types(p<0.05).The WHT cut-off points to predict vitamin D deficiency were 55 days for flame burn(p<0.001)and 62.5 days for electrical burn(p=0.001).Conclusions:WHTacross all three burn typeswas a common factor associated with vitamin D levels for inpatients with burns who had undergone rehabilitative therapy.Electrical burn patients with vitamin D deficiency,even those with a low burned BSA percentage,showed prolonged wound healing over a two-month post-burn period.Independent of burned BSA,nutritional intervention concerning vitamin D in relation to burn wound healing should be considered to guide early initiation of intensive rehabilitation therapy. 展开更多
关键词 Burn factors Vitamin D deficiency Burn type Wound healing time REHABILITATION
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