Quality of Life and Chinese Medicine──The Development of Health Status Measures for Chinese Medicine

Quality of Life (QOL) is a multiphase conception, including physical, mental and social factors, and can overall reflect health status of the human. At present, QOL has become a relevant measure of efficacy of treatment in clinical trials. Its use is spreading, and its importance is growing as a valid indicator of whether or not a medical treatment is

Human embryonic stem cells as an in vitro model for studying developmental origins of type 2 diabetes

The developmental origins of health and diseases(DOHaD)is a concept stating that adverse intrauterine environments contribute to the health risks of offspring.Since the theory emerged more than 30 years ago,many epidemiological and animal studies have confirmed that in utero exposure to environmental insults,including hyperglycemia and chemicals,increased the risk of developing noncommunicable diseases(NCDs).These NCDs include metabolic syndrome,type 2 diabetes,and complications such as diabetic cardiomyopathy.Studying the effects of different environmental insults on early embryo development would aid in understanding the underlying mechanisms by which these insults promote NCD development.Embryonic stem cells(ESCs)have also been utilized by researchers to study the DOHaD.ESCs have pluripotent characteristics and can be differentiated into almost every cell lineage;therefore,they are excellent in vitro models for studying early developmental events.More importantly,human ESCs(hESCs)are the best alternative to human embryos for research because of ethical concerns.In this review,we will discuss different maternal conditions associated with DOHaD,focusing on the complications of maternal diabetes.Next,we will review the differentiation protocols developed to generate different cell lineages from hESCs.Additionally,we will review how hESCs are utilized as a model for research into the DOHaD.The effects of environmental insults on hESC differentiation and the possible involvement of epigenetic regulation will be discussed.

Development of China's Public Health as an Essential Element of Human Rights

September 2017 Contents Preface Ensuring People’s Right to Health Based on China’s Conditions Continuous Improvement of Health Environment and Conditions Public Health Service Capability Improving Steadily Great Improvement in the Quality of Medical and Health Services Improvement of the National Medical Security System

The Relationship of Occupational Health Nurses’ Experiences with Associated Departments in Relation to Project Development of Mental Health Care for Primary Preventive Treatment

Purpose: The purpose of this study was to clarify the relationship and experiences of occupational health nurses (OHNs) and related departments in project development of mental health care for primary treatment in the Japanese occupational health setting. Method: A total of 235 OHNs who are members of the Japan Academy of Occupational Health Nursing were sent an anonymous self-administered questionnaire survey. The questionnaire included items on the following: the OHN’s background, whether the OHN had experience in project development, the communication between the associated departments, the Japanese version of the Work Engagement Scale (UWES-J), occupational assessments, workplace assessments, and the Transtheoretical Model (TTM) for health promotion in companies and the OHN’s working environment. We performed logistic regression analysis to examine the relationship between experience and these harmonious relationships with other associated departments. Result: Responses from 61 OHNs (valid response rate: 25.9%) were analyzed. The mean number of years of service as an OHN was 18.9, and 82% of respondents had experience in project development. The logistic analysis further revealed that OHNs who had experience in project development of mental health care usually had a harmonious relationship with other associated departments. Conclusion: To promote mental health care for workers, OHNs have the capability to create individual and workplace assessments, enhance their work engagement, and make further improvements to their working environment. .

China’s engagement with development assistance for health in Africa

Background:As an emerging donor in health related development across the world,particularly towards Africa,the People’s Republic of China(PRC)has been increasing its influence within the field of global public health over the past few decades.Yet between the period of 2000 and 2013,little is known about the scope,scale and priority of China’s grant-making programs.Methods:Based on data sourced from the China Aid Database(version-1.2),descriptive analyses were applied to analyze the features of 531 health related projects that were undertaken between 2000 and 2013.Spearmen correlation was also performed to assess the relationship between China’s export and aid to recipient countries.Results:The total value of China’s grant-making programs in the health related sector between 2000 and 2013 was 5.67 billion USD,with 531 projects undertaken.During the five year period between 2004 and 2008,China had a contribution of 1.54 billion USD,which increased to 3.8 billion USD during the five year period between 2009 and 2013-an 146.26%increase.In terms of specific diseases,China is most concerned with building an African public health system through donations targeted towards general health(313 projects),combating Malaria(115 projects)and maternal,neonatal and child health(MNCH),(12 projects).When it comes to recipient countries,if counted in total value,Zimbabwe received the most financial assistance from China,totaling 1.08 billion USD and 19 projects,while Angola and Tanzania received more projects-30 and 29 projects respectively.In terms of the channeling of aid funding,most projects were targeted towards infrastructure,equipment and medicine(304 projects in total),followed by medical teams(189 projects).Moreover,there is a statistically significant relationship between aid to Africa and Chinese exports to Africa.Conclusion:During the past decade,Chinese aid projects played an important role in the African public health system through providing funding for infrastructure,equipment and medicine,training health professionals,as well as disease treatment.However,very limited attention was paid towards disease prevention,health promotion and awareness initiatives,and health education.Furthermore,serious questions were raised regarding the long-term financial sustainability and actual impact these projects have on health development.

日本卫生发展援助及其对中国卫生合作的启示

目的梳理日本卫生发展援助现状及策略,探讨其对中国参与国际卫生合作的启示。方法使用PEST分析法,从政治(political)、经济(economic)、社会(social)和技术(technological)四方面分析日本卫生发展援助的外部环境,用近年日本卫生发展援助的统计数据分析日本卫生发展援助的特点,包括援助规模、途径、地区和领域。结果日本卫生发展援助具有有利的社会环境。2012—2016年日本卫生发展援助总额占官方发展援助总额的8.59%,卫生发展援助资金主要由多边机构提供,越南、印度等是援助资金的最大流入国,援助集中解决卫生政策、初级卫生保健等卫生问题。结论建议中国参与国际卫生合作时首先明确自身优势,注重打造国家品牌,通过双边卫生合作助力提升中国多边卫生议题的设置能力,进而提高中国全球卫生治理水平。

What is global health?Key concepts and clarification of misperceptions Report of the 2019 GHRP editorial meeting

The call for“Working Together to Build a Community of Shared Future for Mankind”requires us to improve people’s health across the globe,while global health development entails a satisfactory answer to a fundamental question:“What is global health?”To promote research,teaching,policymaking,and practice in global health,we summarize the main points on the definition of global health from the Editorial Board Meeting of Global Health Research and Policy,convened in July 2019 in Wuhan,China.The meeting functioned as a platform for free brainstorming,indepth discussion,and post-meeting synthesizing.Through the meeting,we have reached a consensus that global health can be considered as a general guiding principle,an organizing framework for thinking and action,a new branch of sciences and specialized discipline in the large family of public health and medicine.The word“global”in global health can be subjective or objective,depending on the context and setting.In addition to dual-,multicountry and global,a project or a study conducted at a local area can be global if it(1)is framed with a global perspective,(2)intends to address an issue with global impact,and/or(3)seeks global solutions to an issue,such as frameworks,strategies,policies,laws,and regulations.In this regard,global health is eventually an extension of“international health”by borrowing related knowledge,theories,technologies and methodologies from public health and medicine.Although global health is a concept that will continue to evolve,our conceptualization through group effort provides,to date,a comprehensive understanding.This report helps to inform individuals in the global health community to advance global health science and practice,and recommend to take advantage of the Belt and Road Initiative proposed by China.

Maternal low protein diet and fetal programming of lean type 2 diabetes

Maternal nutrition is found to be the key factor that determines fetal health in utero and metabolic health during adulthood.Metabolic diseases have been primarily attributed to impaired maternal nutrition during pregnancy,and impaired nutrition has been an immense issue across the globe.In recent years,type 2 diabetes(T2D)has reached epidemic proportion and is a severe public health problem in many countries.Although plenty of research has already been conducted to tackle T2D which is associated with obesity,little is known regarding the etiology and pathophysiology of lean T2D,a variant of T2D.Recent studies have focused on the effects of epigenetic variation on the contribution of in utero origins of lean T2D,although other mechanisms might also contribute to the pathology.Observational studies in humans and experiments in animals strongly suggest an association between maternal low protein diet and lean T2D phenotype.In addition,clear sex-specific disease prevalence was observed in different studies.Consequently,more research is essential for the understanding of the etiology and pathophysiology of lean T2D,which might help to develop better disease prevention and treatment strategies.This review examines the role of protein insufficiency in the maternal diet as the central driver of the developmental programming of lean T2D.

Determinants of China’s development assistance for health at the sub-national level of African countries(2006-2015)

Background:Despite the increasing interest in China’s development assistance for health(DAH)in African countries,little is known regarding the distribution and determinants of China’s DAH project allocation among the principle subdivisions(provinces&states)within African countries.Methods:We mapped the distribution of China’s DAH projects in 670 principle subdivisions of 50 African countries during 2006-2015 using web-based information.The political,demographic,health and socioeconomic indicators of DAH allocation were analyzed using conditional logistic regression models.The national capital city and political leader’s birth place were selected as the main political indicators,and health indicators were selected according to different fields of the DAH projects.Results:China’s DAH projects(mainly China medical teams[CMTs],hospitals and anti-malaria centers)were mostly allocated to the western and eastern coasts of Africa,although CMTs were also dispatched to northern Africa.National capital cities were significantly associated with the allocation of China’s DAH projects(P<0.001).Antimalaria centers were more likely to be allocated to principle subdivisions with larger populations(OR=1.35),and CMTs were allocated to subdivisions with high population densities(OR=79.01).No health-related indicators were identified to affect project allocation except for the facility delivery rate and under-five mortality rate,which were associated with hospital allocation.We also found an association between CMT allocation and the use of artemisinin-based combination therapy in children.Conclusions:Allocation of China’s DAH projects is strongly affected by political and demographic factors.Implementation of China’s new DAH projects should target health and socio-economic indicators and impact metrics in scaling up tailored and cost-effective programs in Africa.

Comprehensive understanding of developmental origins of health and disease concepts: Early intervention to non-communicable diseases in China

Introduction Mortality due to various kinds of noncommunicable diseases (NCDs) has become an increasing focus of attention in recent years.1 With rapidly increasing globalization, lifestyles in low-and middle-income countries increasingly include high-fat diets and inadequate physical exercises are resulting in an increased worldwide burden of NCDs.2,3 A study by the International Diabetes Federation (IDF) showed that about 382 million people had diabetes in 2013, and this will rise to 592 million by 2035.The number of people with type 2 diabetes is increasing in every country, and 80％ of people with diabetes live in low-and middle-income countries.The burden of NCDs and the prevalence of related risk factors such asoverweight and diabetes have also increased in China over the past decades.In 2005, NCDs accounted for an estimated 80％ of deaths and 70％ of disability-adjusted life-years lost in China.

STATISTICAL INFORMATION OF THE DEVELOPMENT OF CHINA'S HEALTH WORK IN 1994

The following general status concerning nation-wide health institutions, hospital beds, personnel and hospital work as well as causes of diseases and death is briefly reported according to the Information Centre of Health Statistics of the Ministry of Public Health of China. HEALTH INSTITUTION, HOSPITAL BEDS AND PERSONNEL In 1994 there was a slight decrease in the number of China’s health institutions while the increasing rate of hospital beds was slowed down and the nmnber of health personnel continued to increase. Health institutions. In 1994 the number of various health institutions in China totalled 191.7 thousand. with a decrease of 1844 as against 1993: there

Industry Development and Health of Chinese Materia Medica and Natura l Products

In order to push forward the research and development of innovative drugs,to re-exploit large species,and to invent healthy product,Tianjin Pharmaceutical Association

Population Development and Reproduction Health Education in Tibet

MY ancestors have lived in Lhasa, Tibet, for generations. I have personally witnessed the great changes in modern Tibetan society. The total population of the region has doubled since 1951. The Fourth National Census in 1990 revealed that the human fertility rate in the Tibet Autonomous Region was 27.60 per thousand, the natural population growth rate 18.40 per thousand, and the total fertility rate of women at childbearing age 4.22.

A look at the ASEAN-NDI: building a regional health R&D innovation network

Globally,there are growing efforts to address diseases through the advancement in health research and development(R&D),strengthening of regional cooperation in science and technology(particularly on product discovery and development),and implementation of the World Health Assembly Resolution 61.21(WHA61.21)on the Global Strategy and Plan of Action on Public Health,Innovation,and Intellectual Property(GSPA-PHI).As such,the Association of Southeast Asian Nations(ASEAN)is responding to this through the establishment of the ASEAN-Network for Drugs,Diagnostics,Vaccines,and Traditional Medicines Innovation(ASEAN-NDI).This is important in the ASEAN considering that infectious tropical diseases remain prevalent,emerging,and reemerging in the region.This paper looks into the evolution of the ASEAN-NDI from its inception in 2009,to how it is at present,and its plans to mitigate public health problems regionally and even globally.