AIM To investigate the relationship between coronary calcium score(CCS) and vulnerable plaque/significant stenosis using coronary computed tomographic angiography(CCTA). METHODS CCTA was performed in 651 patients and ...AIM To investigate the relationship between coronary calcium score(CCS) and vulnerable plaque/significant stenosis using coronary computed tomographic angiography(CCTA). METHODS CCTA was performed in 651 patients and these patients were divided into the four groups(CCS 0, 1-100, 101-400 and > 400). We studied the incidence of high-risk plaque, including positive remodeling, low attenuation plaque, spotty calcification, and napkin-ring sign, and significant stenosis in each group. RESULTS High-risk plaque was found in 1.3%, 10.1%, 13.3% and 13.4% of patients with CCS 0, 1-100, 101-400 and > 400, respectively(P < 0.001). The difference was only significant for patients with zero CCS. The incidence of significant stenosis was 0.6%, 7.6%, 13.3% and 26.9% for each patient group, respectively(P < 0.001), which represented a significant stepwise increase as CCS increased. The combined incidence of high-risk plaque and significant stenosis was 1.9%, 17.7%, 26.9% and 40.3% in each patient group, respectively(P < 0.001), again representing a significant stepwise increase with CCS. The rate of major coronary event was 0%, 4.0%, 7.9% and 17.2% in each patient group, respectively(P < 0.001), another significant stepwise increase as CCS increased. CONCLUSION Stepwise increased risk of coronary events associated with increasing CCS is caused by increasing incidence of significant stenosis, while that of high-risk plaque remains the same.展开更多
目的探讨改良早期预警评分(modified early warning score,MEWS)联合SBAR[现状(situation)、背景(background)、评估(assessment)、建议(recommendation)]沟通模式在高危新生儿中的应用效果,为临床提供一种有效评估患儿病情变化的沟通...目的探讨改良早期预警评分(modified early warning score,MEWS)联合SBAR[现状(situation)、背景(background)、评估(assessment)、建议(recommendation)]沟通模式在高危新生儿中的应用效果,为临床提供一种有效评估患儿病情变化的沟通方法。方法采用前-后对照研究方法,选取2022年8月至9月入住本院新生儿科病房的高危新生儿270例作为研究对象。以8月入院的高危新生儿为对照组,9月入院的高危新生儿作为试验组,每组分别纳入135例患儿。对照组患儿按照常规护理实施病情观察,试验组患儿在对照组基础采用MEWS联合SBAR沟通模式实施病情观察。比较两组高危新生儿预警事件发生情况,护士预警事件与医生处理事件的一致率,医生对护士工作的满意率。结果两组均完成研究。对照组中63.6%的预警事件是由护士发现,试验组中92.6%的预警事件是由护士发现,两组比较,差异具有统计学意义(χ2=16.622,P<0.001)。试验组护士预警事件与医生处理事件的一致性(Kappa系数=0.926)高于对照组(Kappa系数=0.641);试验组医生对护士在专科知识、抢救应急能力、掌握病情情况、及时观察病情变化、医护配合、工作积极性、沟通能力、心理素质方面的满意率均高于对照组(80.0%~95.0%v30.0%~55.0%),两组比较,差异具有统计学意义(均P<0.05)。结论MEWS与SBAR沟通模式联合应用,有助于护士准确评估患儿病情变化,及时有效完成医护沟通,提高护士观察、沟通和处理能力,也提高了医生对护士工作的满意度。展开更多
目的探讨慢性乙型肝炎肝硬化患者aMAP评分与高危食管静脉曲张(HEV)发生风险之间的关联性。方法选取2017年1月1日至2023年1月1日于安徽医科大学第一附属医院确诊为慢性乙型肝炎肝硬化的患者为研究对象。收集所有研究对象的一般资料,同时...目的探讨慢性乙型肝炎肝硬化患者aMAP评分与高危食管静脉曲张(HEV)发生风险之间的关联性。方法选取2017年1月1日至2023年1月1日于安徽医科大学第一附属医院确诊为慢性乙型肝炎肝硬化的患者为研究对象。收集所有研究对象的一般资料,同时收集入院24小时内的实验室检查指标并计算aMAP评分。所有研究对象均完成胃镜检查以评估食管静脉曲张(EV)程度。采用多元Logistic回归评估aMAP评分与HEV风险之间的相关性,采用趋势性检验(P for trend)评估两者之间的相关性是否存在剂量反应关系,最后采用平滑曲线拟合和阈值效应分析明确两者之间是否存在非线性关系。结果最终共纳入患者207例,其中HEV患者104例。与非HEV患者相比,HEV患者aMAP评分更高(P=0.002)。在多个模型中,aMAP评分与HEV之间存在明显的正向相关关系,全调整模型的结果为(OR=1.16,95%CI∶1.03-1.30)。随着aMAP评分的增加,HEV的发生风险也随之增加,趋势性检验具有显著的统计学差异(P for trend<0.01),平滑曲线拟合分析和阈值效应分析提示两者之间为直线效应关系。受试者工作特征曲线(ROC)下面积(AUC)为0.73(0.64-0.78),aMAP评分对HEV诊断的最佳截断值为63.57。结论在慢性乙型肝炎肝硬化患者中,aMAP评分与HEV发病风险之间存在直线性的正性相关关系,并且随着aMAP评分的升高这种正性相关关系更加明显。aMAP评分对HEV具有较好的诊断价值,最佳截断值为63.57。展开更多
文摘AIM To investigate the relationship between coronary calcium score(CCS) and vulnerable plaque/significant stenosis using coronary computed tomographic angiography(CCTA). METHODS CCTA was performed in 651 patients and these patients were divided into the four groups(CCS 0, 1-100, 101-400 and > 400). We studied the incidence of high-risk plaque, including positive remodeling, low attenuation plaque, spotty calcification, and napkin-ring sign, and significant stenosis in each group. RESULTS High-risk plaque was found in 1.3%, 10.1%, 13.3% and 13.4% of patients with CCS 0, 1-100, 101-400 and > 400, respectively(P < 0.001). The difference was only significant for patients with zero CCS. The incidence of significant stenosis was 0.6%, 7.6%, 13.3% and 26.9% for each patient group, respectively(P < 0.001), which represented a significant stepwise increase as CCS increased. The combined incidence of high-risk plaque and significant stenosis was 1.9%, 17.7%, 26.9% and 40.3% in each patient group, respectively(P < 0.001), again representing a significant stepwise increase with CCS. The rate of major coronary event was 0%, 4.0%, 7.9% and 17.2% in each patient group, respectively(P < 0.001), another significant stepwise increase as CCS increased. CONCLUSION Stepwise increased risk of coronary events associated with increasing CCS is caused by increasing incidence of significant stenosis, while that of high-risk plaque remains the same.
文摘目的探讨改良早期预警评分(modified early warning score,MEWS)联合SBAR[现状(situation)、背景(background)、评估(assessment)、建议(recommendation)]沟通模式在高危新生儿中的应用效果,为临床提供一种有效评估患儿病情变化的沟通方法。方法采用前-后对照研究方法,选取2022年8月至9月入住本院新生儿科病房的高危新生儿270例作为研究对象。以8月入院的高危新生儿为对照组,9月入院的高危新生儿作为试验组,每组分别纳入135例患儿。对照组患儿按照常规护理实施病情观察,试验组患儿在对照组基础采用MEWS联合SBAR沟通模式实施病情观察。比较两组高危新生儿预警事件发生情况,护士预警事件与医生处理事件的一致率,医生对护士工作的满意率。结果两组均完成研究。对照组中63.6%的预警事件是由护士发现,试验组中92.6%的预警事件是由护士发现,两组比较,差异具有统计学意义(χ2=16.622,P<0.001)。试验组护士预警事件与医生处理事件的一致性(Kappa系数=0.926)高于对照组(Kappa系数=0.641);试验组医生对护士在专科知识、抢救应急能力、掌握病情情况、及时观察病情变化、医护配合、工作积极性、沟通能力、心理素质方面的满意率均高于对照组(80.0%~95.0%v30.0%~55.0%),两组比较,差异具有统计学意义(均P<0.05)。结论MEWS与SBAR沟通模式联合应用,有助于护士准确评估患儿病情变化,及时有效完成医护沟通,提高护士观察、沟通和处理能力,也提高了医生对护士工作的满意度。
文摘目的探讨慢性乙型肝炎肝硬化患者aMAP评分与高危食管静脉曲张(HEV)发生风险之间的关联性。方法选取2017年1月1日至2023年1月1日于安徽医科大学第一附属医院确诊为慢性乙型肝炎肝硬化的患者为研究对象。收集所有研究对象的一般资料,同时收集入院24小时内的实验室检查指标并计算aMAP评分。所有研究对象均完成胃镜检查以评估食管静脉曲张(EV)程度。采用多元Logistic回归评估aMAP评分与HEV风险之间的相关性,采用趋势性检验(P for trend)评估两者之间的相关性是否存在剂量反应关系,最后采用平滑曲线拟合和阈值效应分析明确两者之间是否存在非线性关系。结果最终共纳入患者207例,其中HEV患者104例。与非HEV患者相比,HEV患者aMAP评分更高(P=0.002)。在多个模型中,aMAP评分与HEV之间存在明显的正向相关关系,全调整模型的结果为(OR=1.16,95%CI∶1.03-1.30)。随着aMAP评分的增加,HEV的发生风险也随之增加,趋势性检验具有显著的统计学差异(P for trend<0.01),平滑曲线拟合分析和阈值效应分析提示两者之间为直线效应关系。受试者工作特征曲线(ROC)下面积(AUC)为0.73(0.64-0.78),aMAP评分对HEV诊断的最佳截断值为63.57。结论在慢性乙型肝炎肝硬化患者中,aMAP评分与HEV发病风险之间存在直线性的正性相关关系,并且随着aMAP评分的升高这种正性相关关系更加明显。aMAP评分对HEV具有较好的诊断价值,最佳截断值为63.57。
