Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and price.This study focuses on 2851 county-level cities in China in 2005–2018(ex...Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and price.This study focuses on 2851 county-level cities in China in 2005–2018(excluding Hong Kong,Macao,Taiwan,and‘no data’areas in Qinhai-Tibet Plateau)as the fundamental units of analysis.By employing nighttime light(NTL)data to identify shrinking cities,the propensity score matching(PSM)model was used to quantitatively examine the impact of shrinking cities on land prices,and evaluate the magnitude of this influence.The findings demonstrate the following:1)there were 613 shrinking cities in China,with moderate shrinkage being the most prevalent and severe shrinkage being the least.2)Regional disparities are evident in the spatial distribution of shrinking cities,especially in areas with diverse terrain.3)The spatial pattern of land price exhibits a significant correlated to the economic and administrative levels.4)Shrinking cities significantly negatively impact on the overall land price(ATT=–0.1241,P<0.05).However,the extent of the effect varies significantly among different spatial regions.This study contributes novel insights into the investigation of land prices and shrinking cities,ultimately serving as a foundation for government efforts to promote the sustainable development of urban areas.展开更多
BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.Howeve...BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.However,conventional diagnostic methods such as electrocardiography,echocardiography,and cardiac biomarkers have certain limitations,such as low sensitivity,specificity,availability,and cost-effectiveness.Therefore,there is a need for simple,noninvasive,and reliable biomarkers to diagnose CHD and HF.AIM To investigate serum cystatin C(Cys-C),monocyte/high-density lipoprotein cholesterol ratio(MHR),and uric acid(UA)diagnostic values for CHD and HF.METHODS We enrolled 80 patients with suspected CHD or HF who were admitted to our hospital between July 2022 and July 2023.The patients were divided into CHD(n=20),HF(n=20),CHD+HF(n=20),and control groups(n=20).The serum levels of Cys-C,MHR,and UA were measured using immunonephelometry and an enzymatic method,respectively,and the diagnostic values for CHD and HF were evaluated using receiver operating characteristic(ROC)curve analysis.RESULTS Serum levels of Cys-C,MHR,and UA were significantly higher in the CHD,HF,and CHD+HF groups than those in the control group.The serum levels of Cys-C,MHR,and UA were significantly higher in the CHD+HF group than those in the CHD or HF group.The ROC curve analysis showed that serum Cys-C,MHR,and UA had good diagnostic performance for CHD and HF,with areas under the curve ranging from 0.78 to 0.93.The optimal cutoff values of serum Cys-C,MHR,and UA for diagnosing CHD,HF,and CHD+HF were 1.2 mg/L,0.9×10^(9),and 389μmol/L;1.4 mg/L,1.0×10^(9),and 449μmol/L;and 1.6 mg/L,1.1×10^(9),and 508μmol/L,respectively.CONCLUSION Serum Cys-C,MHR,and UA are useful biomarkers for diagnosing CHD and HF,and CHD+HF.These can provide information for decision-making and risk stratification in patients with CHD and HF.展开更多
Lignin is the most abundant naturally phenolic biomass,and the synthesis of high-performance renewable fuel from lignin has attracted significant attention.We propose the efficient synthesis of high-density fuels usin...Lignin is the most abundant naturally phenolic biomass,and the synthesis of high-performance renewable fuel from lignin has attracted significant attention.We propose the efficient synthesis of high-density fuels using simulated lignin cracked oil in tandem with hydroalkylation and deoxygenation reactions.First,we investigated the reaction pathway for the hydroalkylation of phenol,which competes with the hydrodeoxygenation form cyclohexane.And then,we investigated the effects of metal catalyst types,the loading amount of metallic,acid dosage,and reactant ratio on the reaction results.The phenol hydroalkylation and hydrodeoxygenation were balanced when 180℃ and 5 MPa H_(2)with the alkanes yield of 95%.By extending the substrate to other lignin-derived phenolics and simulated lignin cracked oil,we obtained the polycyclic alkane fuel with high density of 0.918 g·ml^(-1)and calorific value of41.2 MJ·L^(-1).Besides,the fuel has good low-temperature properties(viscosity of 9.3 mm^(2)·s^(-1)at 20℃ and freezing point below-55℃),which is expected to be used as jet fuel.This work provides a promising way for the easy and green production of high-density fuel directly from real lignin oil.展开更多
Despite the promising potential of transition metal oxides(TMOs)as capacitive deionization(CDI)electrodes,the actual capacity of TMOs electrodes for sodium storage is significantly lower than the theoretical capacity,...Despite the promising potential of transition metal oxides(TMOs)as capacitive deionization(CDI)electrodes,the actual capacity of TMOs electrodes for sodium storage is significantly lower than the theoretical capacity,posing a major obstacle.Herein,we prepared the kinetically favorable Zn_(x)Ni_(1−x)O electrode in situ growth on carbon felt(Zn_(x)Ni_(1−x)O@CF)through constraining the rate of OH^(−)generation in the hydrothermal method.Zn_(x)Ni_(1−x)O@CF exhibited a high-density hierarchical nanosheet structure with three-dimensional open pores,benefitting the ion transport/electron transfer.And tuning the moderate amount of redox-inert Zn-doping can enhance surface electroactive sites,actual activity of redox-active Ni species,and lower adsorption energy,promoting the adsorption kinetic and thermodynamic of the Zn_(0.2)Ni_(0.8)O@CF.Benefitting from the kinetic-thermodynamic facilitation mechanism,Zn_(0.2)Ni_(0.8)O@CF achieved ultrahigh desalination capacity(128.9 mgNaCl g^(-1)),ultra-low energy consumption(0.164 kW h kgNaCl^(-1)),high salt removal rate(1.21 mgNaCl g^(-1) min^(-1)),and good cyclability.The thermodynamic facilitation and Na^(+)intercalation mechanism of Zn_(0.2)Ni_(0.8)O@CF are identified by the density functional theory calculations and electrochemical quartz crystal microbalance with dissipation monitoring,respectively.This research provides new insights into controlling electrochemically favorable morphology and demonstrates that Zn-doping,which is redox-inert,is essential for enhancing the electrochemical performance of CDI electrodes.展开更多
Cultural symbols,a manifestation of cities’cultural resources,are not only signs that frame concepts but also forms that express meanings.Exploring the international communication of cities from the perspective of sy...Cultural symbols,a manifestation of cities’cultural resources,are not only signs that frame concepts but also forms that express meanings.Exploring the international communication of cities from the perspective of symbols,this paper analyzes in depth how cities create their cultural symbols in the dynamic process of international communication in an era of symbol-based digital media,and how they develop their narratives and explain meanings through the dissemination of symbols when telling their stories to international audiences,thus enhancing the efficiency and effectiveness of their international communication efforts.展开更多
In three-dimensional(3D)stacking,the thermal stress of through-silicon via(TSV)has a significant influence on chip performance and reliability,and this problem is exacerbated in high-density TSV arrays.In this study,a...In three-dimensional(3D)stacking,the thermal stress of through-silicon via(TSV)has a significant influence on chip performance and reliability,and this problem is exacerbated in high-density TSV arrays.In this study,a novel hollow tungsten TSV(W-TSV)is presented and developed.The hollow structure provides space for the release of thermal stress.Simulation results showed that the hollow W-TSV structure can release 60.3%of thermal stress within the top 2 lm from the surface,and thermal stress can be decreased to less than 20 MPa in the radial area of 3 lm.The ultra-high-density(1600 TSV∙mm2)TSV array with a size of 640×512,a pitch of 25 lm,and an aspect ratio of 20.3 was fabricated,and the test results demonstrated that the proposed TSV has excellent electrical and reliability performances.The average resistance of the TSV was 1.21 X.The leakage current was 643 pA and the breakdown voltage was greater than 100 V.The resistance change is less than 2%after 100 temperature cycles from40 to 125℃.Raman spectroscopy showed that the maximum stress on the wafer surface caused by the hollow W-TSV was 31.02 MPa,which means that there was no keep-out zone(KOZ)caused by the TSV array.These results indicate that this structure has great potential for applications in large-array photodetectors and 3D integrated circuits.展开更多
The expansion of smart cities,facilitated by digital communications,has resulted in an enhancement of the quality of life and satisfaction among residents.The Internet of Things(IoT)continually generates vast amounts ...The expansion of smart cities,facilitated by digital communications,has resulted in an enhancement of the quality of life and satisfaction among residents.The Internet of Things(IoT)continually generates vast amounts of data,which is subsequently analyzed to offer services to residents.The growth and development of IoT have given rise to a new paradigm.A smart city possesses the ability to consistently monitor and utilize the physical environment,providing intelligent services such as energy,transportation,healthcare,and entertainment for both residents and visitors.Research on the security and privacy of smart cities is increasingly prevalent.These studies highlight the cybersecurity risks and the challenges faced by smart city infrastructure in handling and managing personal data.To effectively uphold individuals’security and privacy,developers of smart cities must earn the trust of the public.In this article,we delve into the realms of privacy and security within smart city applications.Our comprehensive study commences by introducing architecture and various applications tailored to smart cities.Then,concerns surrounding security and privacy within these applications are thoroughly explored subsequently.Following that,we delve into several research endeavors dedicated to addressing security and privacy issues within smart city applications.Finally,we emphasize our methodology and present a case study illustrating privacy and security in smart city contexts.Our proposal consists of defining an Artificial Intelligence(AI)based framework that allows:Thoroughly documenting penetration attempts and cyberattacks;promptly detecting any deviations from security standards;monitoring malicious behaviors and accurately tracing their sources;and establishing strong controls to effectively repel and prevent such threats.Experimental results using the Edge-IIoTset(Edge Industrial Internet of Things Security Evaluation Test)dataset demonstrated good accuracy.They were compared to related state-of-theart works,which highlight the relevance of our proposal.展开更多
Increasing the urban tree cover percentage(TCP) is widely recognized as an efficient way to mitigate the urban heat island effect. The cooling efficiency of urban trees can be either enhanced or attenuated on hotter d...Increasing the urban tree cover percentage(TCP) is widely recognized as an efficient way to mitigate the urban heat island effect. The cooling efficiency of urban trees can be either enhanced or attenuated on hotter days, depending on the physiological response of urban trees to rising ambient temperature. However, the response of urban trees' cooling efficiency to rising urban temperature remains poorly quantified for China's cities. In this study, we quantify the response of urban trees' cooling efficiency to rising urban temperature at noontime [~1330 LT(local time), LT=UTC+8] in 17summers(June, July, and August) from 2003–19 in 70 economically developed cities of China based on satellite observations. The results show that urban trees have stronger cooling efficiency with increasing temperature, suggesting additional cooling benefits provided by urban trees on hotter days. The enhanced cooling efficiency values of urban trees range from 0.002 to 0.055℃ %-1 per 1℃ increase in temperature across the selected cities, with larger values for the lowTCP-level cities. The response is also regulated by background temperature and precipitation, as the additional cooling benefit tends to be larger in warmer and wetter cities at the same TCP level. The positive response of urban trees' cooling efficiency to rising urban temperature is explained mainly by the stronger evapotranspiration of urban trees on hotter days.These results have important implications for alleviating urban heat risk by utilizing urban trees, particularly considering that extreme hot days are becoming more frequent in cities under global warming.展开更多
BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial a...BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial and unclear,which requires further investigation.In this prospective study,96 patients with acute ischemic stroke(AIS)who accepted endovascular mechanical thrombectomy(EMT)were included.The enrolled patients underwent cranial computed tomography(CT)examination within 24 hours after EMT.Clinical data in terms of National Institutes of Health Stroke Scale(NIHSS),the 3-month modified Rankin Scale(mRS),self-rating depression scale(SDS),and self-rating anxiety scale(SAS)scores were collected and compared between patients with HDAs and non-HDAs and between patients with good and poor clinical prognosis.Compared to patients without HDAs,patients with HDAs presented severe neurological deficits(admission NIHSS score:18±3 vs 19±4),were more likely to have post-stroke disabilities(mRS<3:35%vs 62%),and suffered more severe depression(SDS score:58±16 vs 64±13)and anxiety disorder(SAS score:52±8 vs 59±10).Compared to patients with a good prognosis,patients with a poor prognosis presented severe neurological deficits(admission NIHSS score:17±4 vs 20±3),were more likely to have HDAs on CT images(64%vs 33%),and suffered more severe depression(SDS score:55±19 vs 65±11)and anxiety(SAS score:50±8 vs 58±12).Multivariate analysis revealed that HDAs were independent nega-tive prognostic factors.CONCLUSION In conclusion,HDAs on CT images predicted poor prognosis and severe depressive and anxiety symptoms in patients with AIS who underwent EMT.展开更多
Smart cities are a way for China to construct an innovative and environmentally conscious nation.The paper examines the impact of smart cities on corporate green governance and provides a theoretical foundation for fo...Smart cities are a way for China to construct an innovative and environmentally conscious nation.The paper examines the impact of smart cities on corporate green governance and provides a theoretical foundation for formulating and executing smart city policy in China.Based on panel data from Chinese A-share listed companies in Shanghai and Shenzhen from 2008 to 2020,this study constructs a multiperiod double-difference model to examine the influence of smart cities on corporate green governance.Additionally,it uses a spatial double-difference model to investigate the spatial spillover effect of smart cities on neighboring areas.The findings indicate that smart cities effectively enhance corporate green governance.Analyzing the influencing mechanisms reveals that resource allocation efficiency,technological innovation,management environmental awareness,and regional environmental enforcement efforts act as mediators.Furthermore,the study reveals that the impact of smart cities on promoting corporate green governance is more pronounced in regions with lower levels of marketization and resource-based cities.Moreover,the research explores the spatial spillover effects of smart cities,with an effective radius of approximately 350 km.The optimal spatial correlation zone for green governance of businesses in neighboring areas in relation to smart cities is within a range of 250-350 km.This is manifested by the significant promotion of green governance in neighboring area businesses facilitated by smart cities.展开更多
Few studies have investigated the spatial patterns of the air temperature urban heat island(AUHI)and its controlling factors.In this study,the data generated by an urban climate model were used to investigate the spat...Few studies have investigated the spatial patterns of the air temperature urban heat island(AUHI)and its controlling factors.In this study,the data generated by an urban climate model were used to investigate the spatial variations of the AUHI across China and the underlying climate and ecological drivers.A total of 355 urban clusters were used.We performed an attribution analysis of the AUHI to elucidate the mechanisms underlying its formation.The results show that the midday AUHI is negatively correlated with climate wetness(humid:0.34 K;semi-humid:0.50 K;semi-arid:0.73 K).The annual mean midnight AUHI does not show discernible spatial patterns,but is generally stronger than the midday AUHI.The urban–rural difference in convection efficiency is the largest contributor to the midday AUHI in the humid(0.32±0.09 K)and the semi-arid(0.36±0.11 K)climate zones.The release of anthropogenic heat from urban land is the dominant contributor to the midnight AUHI in all three climate zones.The rural vegetation density is the most important driver of the daytime and nighttime AUHI spatial variations.A spatial covariance analysis revealed that this vegetation influence is manifested mainly through its regulation of heat storage in rural land.展开更多
Big data and information and communication technologies can be important to the effectiveness of smart cities.Based on the maximal attention on smart city sustainability,developing data-driven smart cities is newly ob...Big data and information and communication technologies can be important to the effectiveness of smart cities.Based on the maximal attention on smart city sustainability,developing data-driven smart cities is newly obtained attention as a vital technology for addressing sustainability problems.Real-time monitoring of pollution allows local authorities to analyze the present traffic condition of cities and make decisions.Relating to air pollution occurs a main environmental problem in smart city environments.The effect of the deep learning(DL)approach quickly increased and penetrated almost every domain,comprising air pollution forecast.Therefore,this article develops a new Coot Optimization Algorithm with an Ensemble Deep Learning based Air Pollution Prediction(COAEDL-APP)system for Sustainable Smart Cities.The projected COAEDL-APP algorithm accurately forecasts the presence of air quality in the sustainable smart city environment.To achieve this,the COAEDL-APP technique initially performs a linear scaling normalization(LSN)approach to pre-process the input data.For air quality prediction,an ensemble of three DL models has been involved,namely autoencoder(AE),long short-term memory(LSTM),and deep belief network(DBN).Furthermore,the COA-based hyperparameter tuning procedure can be designed to adjust the hyperparameter values of the DL models.The simulation outcome of the COAEDL-APP algorithm was tested on the air quality database,and the outcomes stated the improved performance of the COAEDL-APP algorithm over other existing systems with maximum accuracy of 98.34%.展开更多
As part of its efforts to promote a sustainable and high-quality development,China has pledged to reduce water consumption and create a water-efficient society.On the basis of identifying the institutional root causes...As part of its efforts to promote a sustainable and high-quality development,China has pledged to reduce water consumption and create a water-efficient society.On the basis of identifying the institutional root causes of excessive capital allocation and excessive water consumption in China’s water-intensive industrial sectors,this study elaborates how the national water-efficient cities assessment contributes to optimized capital allocation.Our research shows that national water-efficient cities assessment has motivated local governments to compete for water efficiency.To conserve water,local governments regulated the entry and exit of water-intensive enterprises,discouraged excessive investments in water-intensive sectors,and phased out obsolete water-intensive capacities within their jurisdictions.This approach has resulted in mutually beneficial outcomes,including improved allocation of capital,enhanced water efficiency,and reduced emissions.This paper offers policy recommendations for establishing a water-efficient society throughout the 14^(th) Five-Year Plan(2021-2025)period by presenting empirical evidence on the policy effects of resource efficiency evaluation.展开更多
Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern Ch...Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern China from 2000 to 2018,this study explores the coupling coordination development of port and city environments and its impact on urban economic competitiveness by constructing the coupling coordination degree model and the panel threshold model.The research results show that:(1)In terms of the coupling coordination development of port and city environments,most coastal ports and their hinterland cities are in a state of moderate or serious disorder.Overall,the degree of coupling coordination of port and city environments needs to be further improved;(2)The coupling coordination degree of port and city environments has a significant impact on urban economic competitiveness,and this effect gradually increases with the development of the ports and the urban economy.Among the variables that impact the urban economic competitiveness,fixed assets investment and foreign trade are significant factors that can enhance urban economic competitiveness.(3)At present,there is a“U-shaped”relationship between the coupling coordination degree of port-city environments and the urban economic competitiveness.This relationship lies on the right side of the inflection point of the“U-shaped”curve.Therefore,following the concept of assigning priority to ecological development,expanding fixed assets investment and actively developing foreign trade can further enhance the urban economic competitiveness.展开更多
Under the influence of special terrain and climatic conditions,lightning weather in Ulanqab City is more frequent from June to August,and lightning disaster has become one of the important tasks of disaster prevention...Under the influence of special terrain and climatic conditions,lightning weather in Ulanqab City is more frequent from June to August,and lightning disaster has become one of the important tasks of disaster prevention and mitigation.In this paper,based on the characteristics of lightning weather in Ulanqab City,the impact of lightning disaster on the city was analyzed,and lightning protection measures,such as strengthening supervision of lightning protection safety,establishing a long-term lightning protection mechanism,doing a good job in lightning protection construction and detection in key places,and further improving public awareness of lightning protection,were put forward to reduce and avoid urban lightning disasters as much as possible and ensure urban safety.展开更多
With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cit...With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cities,the commuting space of 11 primary and secondary schools in Bajiao Street is analyzed through literature analysis and field research methods.Firstly,the relevant literature on school commuting space is sorted out,and the characteristics of school commuting space are summarized,including transportation,landscape,culture,leisure,and security.Secondly,the characteristics of commuting space of primary and secondary schools in Bajiao Street are analyzed from three aspects:in front of the school gate,path space,and node space.This paper aims to provide reference and guidance for the future construction of children’s walking school commuting and promote the construction of a child friendly city.展开更多
Green transformation is an unavoidable choice for resource-based cities(RBCs)that face resource depletion and environmental pollution.Existing research has focused primarily on specific RBCs,making it challenging to a...Green transformation is an unavoidable choice for resource-based cities(RBCs)that face resource depletion and environmental pollution.Existing research has focused primarily on specific RBCs,making it challenging to apply green transformation strategies universally across cities.The fuzzy set qualitative comparative analysis(fsQCA)is a combination of qualitative and quantitative analyses that can handle multiple concurrent causality problems and determine how different conditions combine into configurations and generate an outcome.Thus,to address this gap,in this study,we established a research framework for green transformation and utilized the fsQCA to examine the configurations of 113 RBCs in China.By incorporating the element of time,this study explored the dynamic evolution of solutions in 2013,2016,and 2019.The main findings indicate that individual elements do not constitute the necessary conditions for improving the green transformation efficiency(GTE),and the systematic combination of multiple conditions is an effective path for realizing the improvement of the GTE in RBCs.Green transformation paths of RBCs exhibit the same destination through different paths.Additionally,the combination of system environment elements and system structure elements is both complementary and alternative.Differences in RBCs have led to various factor combinations and development paths,but there are some similarities in the key elements of the factor combinations at different stages.Economic environment,government support,and technological innovation are key factors that universally enhance the GTE in RBCs.These insights can assist city managers in formulating policies to drive green transformation and contribute to a better theoretical understanding of green transformation paths in RBCs.展开更多
Digital technology provides a method of quantitative investigation and data analysis for contemporary landscape spatial analysis,and related research is moving from image recognition to digital algorithmic analysis,pr...Digital technology provides a method of quantitative investigation and data analysis for contemporary landscape spatial analysis,and related research is moving from image recognition to digital algorithmic analysis,providing a more scientific and macroscopic way of research.The key to refinement design is to refine the spatial design process and the spatial improvement strategy system.Taking the ancient city of Zhaoyu in Qixian County,Shanxi Province as an example,(1)based on obtaining the integrated data of the ancient city through the drone tilt photography,the style and landscape of the ancient city are modeled;(2)the point cloud data with spatial information is imported into the point cloud analysis platform and the data analysis is carried out from the overall macroscopic style of the ancient city to the refinement level,which results in the formation of a more intuitive landscape design scheme,thus improving the precision and practicability of the landscape design;(3)Based on spatial big data,it starts from the spatial aggregation level,spatial distribution characteristics and other evaluation index system to achieve the refinement analysis of the site.Digital technology and methods are used throughout the process to explore the refined design path.展开更多
Background:Helicobacter pylori(HP)is associated with several gastrointestinal diseases,including peptic ulcer diseases and gastric cancer,and non-gastrointestinal diseases such as hypertension and Alzheimer's dise...Background:Helicobacter pylori(HP)is associated with several gastrointestinal diseases,including peptic ulcer diseases and gastric cancer,and non-gastrointestinal diseases such as hypertension and Alzheimer's disease.However,the relationship between HP and lipid metabolism and atherosclerosis remains unclear.This study aims to investigate the association between H.pylori infection and high-density lipoprotein cholesterol levels and pulse wave conduction velocity.Methods:This is a report of a cross-sectional study that collected data from 2,827 participants.The data collected included results of life questionnaires,laboratory tests,13C-urea breath test(13C-UBT),and pulse wave conduction velocity test.Based on the results of the 13C-UBT test,the subjects were divided into two groups:the HP-uninfected group(HP−)and the HP-infected group(HP+).The study compared the differences in HDL-C levels and brachial-ankle pulse wave velocity(baPWV)between the two groups.One-way regression analysis was used to identify potential factors affecting HDL-C levels in the study population.Multiple regression equations were presented to analyze whether HP infection was an independent risk factor for abnormal HDL-C metabolism in the population.Results:Univariate analysis demonstrated that high-density lipoprotein cholesterol(HDL-C)levels were significantly lower in the HP+group compared to the HP−group,with a mean difference ofβ=−18.1 mg/dl(95%CI:−19.3 to−17.0,P<0.001).After adjusting for all variables,the HDL-C levels remained lower in the HP+group compared to the HP-group,with a mean difference ofβ=−17.4 mg/dl(95%CI:−18.2 to−16.7,P<0.001).These findings suggest that H.pylori infection is independently associated with abnormal HDL-C metabolism.Additionally,brachial-ankle pulse wave velocity(baPWV)was higher in the HP+group than in the HP−group on both sides.On the right side,the baPWV was 1,713.4±231.4 cm/s in the HP+group compared to 1,542.8±237.5 cm/s in the HP−group(t=−18.30,P<0.001).On the left side,the baPWV was 1,743.7±238.8 cm/s in the HP+group compared to 1,562.8±256.3 cm/s in the HP−group(t=−18.23,P<0.001).These results indicate a significant association between H.pylori infection and increased arterial stiffness,as measured by baPWV.Conclusion:Helicobacter pylori infection is associated with a decrease in high-density lipoprotein cholesterol levels and an increase in pulse wave conduction velocity.展开更多
With the development of society,more and more cities are participating in the initiative to build learning cities.Constructing an evaluation indicator system for learning cities to monitor the progress and promote the...With the development of society,more and more cities are participating in the initiative to build learning cities.Constructing an evaluation indicator system for learning cities to monitor the progress and promote their growth has become increasingly important.This paper analyzes the preliminary framework of the UNESCO Global Learning City Index and R3L+Quality Framework.The comparison is made from the aspects of design philosophy,criteria of indicator,and the cycle of evaluation process.The findings suggest that the construction of an evaluation indicator system should be focused more on the diversity of learning city development,the construction of an evaluation process cycle,and the significance of building cooperative networks.展开更多
基金Under the auspices of National Natural Science Foundation of China(No.42071222,41771194)。
文摘Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and price.This study focuses on 2851 county-level cities in China in 2005–2018(excluding Hong Kong,Macao,Taiwan,and‘no data’areas in Qinhai-Tibet Plateau)as the fundamental units of analysis.By employing nighttime light(NTL)data to identify shrinking cities,the propensity score matching(PSM)model was used to quantitatively examine the impact of shrinking cities on land prices,and evaluate the magnitude of this influence.The findings demonstrate the following:1)there were 613 shrinking cities in China,with moderate shrinkage being the most prevalent and severe shrinkage being the least.2)Regional disparities are evident in the spatial distribution of shrinking cities,especially in areas with diverse terrain.3)The spatial pattern of land price exhibits a significant correlated to the economic and administrative levels.4)Shrinking cities significantly negatively impact on the overall land price(ATT=–0.1241,P<0.05).However,the extent of the effect varies significantly among different spatial regions.This study contributes novel insights into the investigation of land prices and shrinking cities,ultimately serving as a foundation for government efforts to promote the sustainable development of urban areas.
文摘BACKGROUND Coronary heart disease(CHD)and heart failure(HF)are the major causes of morbidity and mortality worldwide.Early and accurate diagnoses of CHD and HF are essential for optimal management and prognosis.However,conventional diagnostic methods such as electrocardiography,echocardiography,and cardiac biomarkers have certain limitations,such as low sensitivity,specificity,availability,and cost-effectiveness.Therefore,there is a need for simple,noninvasive,and reliable biomarkers to diagnose CHD and HF.AIM To investigate serum cystatin C(Cys-C),monocyte/high-density lipoprotein cholesterol ratio(MHR),and uric acid(UA)diagnostic values for CHD and HF.METHODS We enrolled 80 patients with suspected CHD or HF who were admitted to our hospital between July 2022 and July 2023.The patients were divided into CHD(n=20),HF(n=20),CHD+HF(n=20),and control groups(n=20).The serum levels of Cys-C,MHR,and UA were measured using immunonephelometry and an enzymatic method,respectively,and the diagnostic values for CHD and HF were evaluated using receiver operating characteristic(ROC)curve analysis.RESULTS Serum levels of Cys-C,MHR,and UA were significantly higher in the CHD,HF,and CHD+HF groups than those in the control group.The serum levels of Cys-C,MHR,and UA were significantly higher in the CHD+HF group than those in the CHD or HF group.The ROC curve analysis showed that serum Cys-C,MHR,and UA had good diagnostic performance for CHD and HF,with areas under the curve ranging from 0.78 to 0.93.The optimal cutoff values of serum Cys-C,MHR,and UA for diagnosing CHD,HF,and CHD+HF were 1.2 mg/L,0.9×10^(9),and 389μmol/L;1.4 mg/L,1.0×10^(9),and 449μmol/L;and 1.6 mg/L,1.1×10^(9),and 508μmol/L,respectively.CONCLUSION Serum Cys-C,MHR,and UA are useful biomarkers for diagnosing CHD and HF,and CHD+HF.These can provide information for decision-making and risk stratification in patients with CHD and HF.
基金the support from National Key Research and Development Program of China(2021YFC2104400)the Tianjin Science and Technology Plan Project(21JCQNJC00340)the Haihe Laboratory of Sustainable Chemical Transformations for financial support。
文摘Lignin is the most abundant naturally phenolic biomass,and the synthesis of high-performance renewable fuel from lignin has attracted significant attention.We propose the efficient synthesis of high-density fuels using simulated lignin cracked oil in tandem with hydroalkylation and deoxygenation reactions.First,we investigated the reaction pathway for the hydroalkylation of phenol,which competes with the hydrodeoxygenation form cyclohexane.And then,we investigated the effects of metal catalyst types,the loading amount of metallic,acid dosage,and reactant ratio on the reaction results.The phenol hydroalkylation and hydrodeoxygenation were balanced when 180℃ and 5 MPa H_(2)with the alkanes yield of 95%.By extending the substrate to other lignin-derived phenolics and simulated lignin cracked oil,we obtained the polycyclic alkane fuel with high density of 0.918 g·ml^(-1)and calorific value of41.2 MJ·L^(-1).Besides,the fuel has good low-temperature properties(viscosity of 9.3 mm^(2)·s^(-1)at 20℃ and freezing point below-55℃),which is expected to be used as jet fuel.This work provides a promising way for the easy and green production of high-density fuel directly from real lignin oil.
基金supported by The National Natural Science Foundation of China(22276137,52170087)the Fundamental Research Funds for the Central Universities(XJEDU2023Z009).
文摘Despite the promising potential of transition metal oxides(TMOs)as capacitive deionization(CDI)electrodes,the actual capacity of TMOs electrodes for sodium storage is significantly lower than the theoretical capacity,posing a major obstacle.Herein,we prepared the kinetically favorable Zn_(x)Ni_(1−x)O electrode in situ growth on carbon felt(Zn_(x)Ni_(1−x)O@CF)through constraining the rate of OH^(−)generation in the hydrothermal method.Zn_(x)Ni_(1−x)O@CF exhibited a high-density hierarchical nanosheet structure with three-dimensional open pores,benefitting the ion transport/electron transfer.And tuning the moderate amount of redox-inert Zn-doping can enhance surface electroactive sites,actual activity of redox-active Ni species,and lower adsorption energy,promoting the adsorption kinetic and thermodynamic of the Zn_(0.2)Ni_(0.8)O@CF.Benefitting from the kinetic-thermodynamic facilitation mechanism,Zn_(0.2)Ni_(0.8)O@CF achieved ultrahigh desalination capacity(128.9 mgNaCl g^(-1)),ultra-low energy consumption(0.164 kW h kgNaCl^(-1)),high salt removal rate(1.21 mgNaCl g^(-1) min^(-1)),and good cyclability.The thermodynamic facilitation and Na^(+)intercalation mechanism of Zn_(0.2)Ni_(0.8)O@CF are identified by the density functional theory calculations and electrochemical quartz crystal microbalance with dissipation monitoring,respectively.This research provides new insights into controlling electrochemically favorable morphology and demonstrates that Zn-doping,which is redox-inert,is essential for enhancing the electrochemical performance of CDI electrodes.
文摘Cultural symbols,a manifestation of cities’cultural resources,are not only signs that frame concepts but also forms that express meanings.Exploring the international communication of cities from the perspective of symbols,this paper analyzes in depth how cities create their cultural symbols in the dynamic process of international communication in an era of symbol-based digital media,and how they develop their narratives and explain meanings through the dissemination of symbols when telling their stories to international audiences,thus enhancing the efficiency and effectiveness of their international communication efforts.
基金supported by the National Key Research and Development Program of China(2021YFB2011700).
文摘In three-dimensional(3D)stacking,the thermal stress of through-silicon via(TSV)has a significant influence on chip performance and reliability,and this problem is exacerbated in high-density TSV arrays.In this study,a novel hollow tungsten TSV(W-TSV)is presented and developed.The hollow structure provides space for the release of thermal stress.Simulation results showed that the hollow W-TSV structure can release 60.3%of thermal stress within the top 2 lm from the surface,and thermal stress can be decreased to less than 20 MPa in the radial area of 3 lm.The ultra-high-density(1600 TSV∙mm2)TSV array with a size of 640×512,a pitch of 25 lm,and an aspect ratio of 20.3 was fabricated,and the test results demonstrated that the proposed TSV has excellent electrical and reliability performances.The average resistance of the TSV was 1.21 X.The leakage current was 643 pA and the breakdown voltage was greater than 100 V.The resistance change is less than 2%after 100 temperature cycles from40 to 125℃.Raman spectroscopy showed that the maximum stress on the wafer surface caused by the hollow W-TSV was 31.02 MPa,which means that there was no keep-out zone(KOZ)caused by the TSV array.These results indicate that this structure has great potential for applications in large-array photodetectors and 3D integrated circuits.
文摘The expansion of smart cities,facilitated by digital communications,has resulted in an enhancement of the quality of life and satisfaction among residents.The Internet of Things(IoT)continually generates vast amounts of data,which is subsequently analyzed to offer services to residents.The growth and development of IoT have given rise to a new paradigm.A smart city possesses the ability to consistently monitor and utilize the physical environment,providing intelligent services such as energy,transportation,healthcare,and entertainment for both residents and visitors.Research on the security and privacy of smart cities is increasingly prevalent.These studies highlight the cybersecurity risks and the challenges faced by smart city infrastructure in handling and managing personal data.To effectively uphold individuals’security and privacy,developers of smart cities must earn the trust of the public.In this article,we delve into the realms of privacy and security within smart city applications.Our comprehensive study commences by introducing architecture and various applications tailored to smart cities.Then,concerns surrounding security and privacy within these applications are thoroughly explored subsequently.Following that,we delve into several research endeavors dedicated to addressing security and privacy issues within smart city applications.Finally,we emphasize our methodology and present a case study illustrating privacy and security in smart city contexts.Our proposal consists of defining an Artificial Intelligence(AI)based framework that allows:Thoroughly documenting penetration attempts and cyberattacks;promptly detecting any deviations from security standards;monitoring malicious behaviors and accurately tracing their sources;and establishing strong controls to effectively repel and prevent such threats.Experimental results using the Edge-IIoTset(Edge Industrial Internet of Things Security Evaluation Test)dataset demonstrated good accuracy.They were compared to related state-of-theart works,which highlight the relevance of our proposal.
基金supported by the Natural Science Foundation of Jiangsu Province (Grant No. BK20240170)Open fund by Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (KHK2203)+2 种基金the Jiangsu Meteorological Bureau Youth Fund (KQ202314)the Fundamental Research Funds for the Central Universities (2024300330)Jiangsu Collaborative Innovation Center for Climate Change。
文摘Increasing the urban tree cover percentage(TCP) is widely recognized as an efficient way to mitigate the urban heat island effect. The cooling efficiency of urban trees can be either enhanced or attenuated on hotter days, depending on the physiological response of urban trees to rising ambient temperature. However, the response of urban trees' cooling efficiency to rising urban temperature remains poorly quantified for China's cities. In this study, we quantify the response of urban trees' cooling efficiency to rising urban temperature at noontime [~1330 LT(local time), LT=UTC+8] in 17summers(June, July, and August) from 2003–19 in 70 economically developed cities of China based on satellite observations. The results show that urban trees have stronger cooling efficiency with increasing temperature, suggesting additional cooling benefits provided by urban trees on hotter days. The enhanced cooling efficiency values of urban trees range from 0.002 to 0.055℃ %-1 per 1℃ increase in temperature across the selected cities, with larger values for the lowTCP-level cities. The response is also regulated by background temperature and precipitation, as the additional cooling benefit tends to be larger in warmer and wetter cities at the same TCP level. The positive response of urban trees' cooling efficiency to rising urban temperature is explained mainly by the stronger evapotranspiration of urban trees on hotter days.These results have important implications for alleviating urban heat risk by utilizing urban trees, particularly considering that extreme hot days are becoming more frequent in cities under global warming.
文摘BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial and unclear,which requires further investigation.In this prospective study,96 patients with acute ischemic stroke(AIS)who accepted endovascular mechanical thrombectomy(EMT)were included.The enrolled patients underwent cranial computed tomography(CT)examination within 24 hours after EMT.Clinical data in terms of National Institutes of Health Stroke Scale(NIHSS),the 3-month modified Rankin Scale(mRS),self-rating depression scale(SDS),and self-rating anxiety scale(SAS)scores were collected and compared between patients with HDAs and non-HDAs and between patients with good and poor clinical prognosis.Compared to patients without HDAs,patients with HDAs presented severe neurological deficits(admission NIHSS score:18±3 vs 19±4),were more likely to have post-stroke disabilities(mRS<3:35%vs 62%),and suffered more severe depression(SDS score:58±16 vs 64±13)and anxiety disorder(SAS score:52±8 vs 59±10).Compared to patients with a good prognosis,patients with a poor prognosis presented severe neurological deficits(admission NIHSS score:17±4 vs 20±3),were more likely to have HDAs on CT images(64%vs 33%),and suffered more severe depression(SDS score:55±19 vs 65±11)and anxiety(SAS score:50±8 vs 58±12).Multivariate analysis revealed that HDAs were independent nega-tive prognostic factors.CONCLUSION In conclusion,HDAs on CT images predicted poor prognosis and severe depressive and anxiety symptoms in patients with AIS who underwent EMT.
基金Supported National Social Science Foundation of China[Grant No.18BGL085]Postgraduate Scientific Research Innovation Project of Jiangsu Province[Grant No.KYCX23_0832].
文摘Smart cities are a way for China to construct an innovative and environmentally conscious nation.The paper examines the impact of smart cities on corporate green governance and provides a theoretical foundation for formulating and executing smart city policy in China.Based on panel data from Chinese A-share listed companies in Shanghai and Shenzhen from 2008 to 2020,this study constructs a multiperiod double-difference model to examine the influence of smart cities on corporate green governance.Additionally,it uses a spatial double-difference model to investigate the spatial spillover effect of smart cities on neighboring areas.The findings indicate that smart cities effectively enhance corporate green governance.Analyzing the influencing mechanisms reveals that resource allocation efficiency,technological innovation,management environmental awareness,and regional environmental enforcement efforts act as mediators.Furthermore,the study reveals that the impact of smart cities on promoting corporate green governance is more pronounced in regions with lower levels of marketization and resource-based cities.Moreover,the research explores the spatial spillover effects of smart cities,with an effective radius of approximately 350 km.The optimal spatial correlation zone for green governance of businesses in neighboring areas in relation to smart cities is within a range of 250-350 km.This is manifested by the significant promotion of green governance in neighboring area businesses facilitated by smart cities.
基金supported by the National Key R&D Program of China (Grant No.2019YFA0607202)the National Natural Science Foundation of China (Grant Nos. 42021004 and 42005143)+2 种基金support by the Postgraduate Research&Practice Innovation Program of Jiangsu Province (Grant No. KYCX21_0978)support by the Open Research Fund Program of the Key Laboratory of Urban Meteorology,China Meteorological Administration (Grant No. LUM-2023-12)the 333 Project of Jiangsu Province (Grant No. BRA2022023)
文摘Few studies have investigated the spatial patterns of the air temperature urban heat island(AUHI)and its controlling factors.In this study,the data generated by an urban climate model were used to investigate the spatial variations of the AUHI across China and the underlying climate and ecological drivers.A total of 355 urban clusters were used.We performed an attribution analysis of the AUHI to elucidate the mechanisms underlying its formation.The results show that the midday AUHI is negatively correlated with climate wetness(humid:0.34 K;semi-humid:0.50 K;semi-arid:0.73 K).The annual mean midnight AUHI does not show discernible spatial patterns,but is generally stronger than the midday AUHI.The urban–rural difference in convection efficiency is the largest contributor to the midday AUHI in the humid(0.32±0.09 K)and the semi-arid(0.36±0.11 K)climate zones.The release of anthropogenic heat from urban land is the dominant contributor to the midnight AUHI in all three climate zones.The rural vegetation density is the most important driver of the daytime and nighttime AUHI spatial variations.A spatial covariance analysis revealed that this vegetation influence is manifested mainly through its regulation of heat storage in rural land.
基金funded by the Deanship of Scientific Research(DSR),King Abdulaziz University(KAU),Jeddah,Saudi Arabia under Grant No.(IFPIP:631-612-1443).
文摘Big data and information and communication technologies can be important to the effectiveness of smart cities.Based on the maximal attention on smart city sustainability,developing data-driven smart cities is newly obtained attention as a vital technology for addressing sustainability problems.Real-time monitoring of pollution allows local authorities to analyze the present traffic condition of cities and make decisions.Relating to air pollution occurs a main environmental problem in smart city environments.The effect of the deep learning(DL)approach quickly increased and penetrated almost every domain,comprising air pollution forecast.Therefore,this article develops a new Coot Optimization Algorithm with an Ensemble Deep Learning based Air Pollution Prediction(COAEDL-APP)system for Sustainable Smart Cities.The projected COAEDL-APP algorithm accurately forecasts the presence of air quality in the sustainable smart city environment.To achieve this,the COAEDL-APP technique initially performs a linear scaling normalization(LSN)approach to pre-process the input data.For air quality prediction,an ensemble of three DL models has been involved,namely autoencoder(AE),long short-term memory(LSTM),and deep belief network(DBN).Furthermore,the COA-based hyperparameter tuning procedure can be designed to adjust the hyperparameter values of the DL models.The simulation outcome of the COAEDL-APP algorithm was tested on the air quality database,and the outcomes stated the improved performance of the COAEDL-APP algorithm over other existing systems with maximum accuracy of 98.34%.
基金Sponsorship of the Outstanding Youth Innovation Team Development Program for Institutes of Higher Learning in Shandong Province(2021RW008)the Youth Program of the Natural Science Foundation of Shandong Province(ZR2021QG048).
文摘As part of its efforts to promote a sustainable and high-quality development,China has pledged to reduce water consumption and create a water-efficient society.On the basis of identifying the institutional root causes of excessive capital allocation and excessive water consumption in China’s water-intensive industrial sectors,this study elaborates how the national water-efficient cities assessment contributes to optimized capital allocation.Our research shows that national water-efficient cities assessment has motivated local governments to compete for water efficiency.To conserve water,local governments regulated the entry and exit of water-intensive enterprises,discouraged excessive investments in water-intensive sectors,and phased out obsolete water-intensive capacities within their jurisdictions.This approach has resulted in mutually beneficial outcomes,including improved allocation of capital,enhanced water efficiency,and reduced emissions.This paper offers policy recommendations for establishing a water-efficient society throughout the 14^(th) Five-Year Plan(2021-2025)period by presenting empirical evidence on the policy effects of resource efficiency evaluation.
基金This research is supported by Hunan Provincial Natural Science Foundation of China(Grant No.2021JJ30304)the General Topics of Hunan Social Science Achievement Evaluation Committee of China(Grant No.XSP22YBC366)the Key Scientific Research Project of Hunan Provincial Department of Education of China(Grant No.21B0592).
文摘Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern China from 2000 to 2018,this study explores the coupling coordination development of port and city environments and its impact on urban economic competitiveness by constructing the coupling coordination degree model and the panel threshold model.The research results show that:(1)In terms of the coupling coordination development of port and city environments,most coastal ports and their hinterland cities are in a state of moderate or serious disorder.Overall,the degree of coupling coordination of port and city environments needs to be further improved;(2)The coupling coordination degree of port and city environments has a significant impact on urban economic competitiveness,and this effect gradually increases with the development of the ports and the urban economy.Among the variables that impact the urban economic competitiveness,fixed assets investment and foreign trade are significant factors that can enhance urban economic competitiveness.(3)At present,there is a“U-shaped”relationship between the coupling coordination degree of port-city environments and the urban economic competitiveness.This relationship lies on the right side of the inflection point of the“U-shaped”curve.Therefore,following the concept of assigning priority to ecological development,expanding fixed assets investment and actively developing foreign trade can further enhance the urban economic competitiveness.
文摘Under the influence of special terrain and climatic conditions,lightning weather in Ulanqab City is more frequent from June to August,and lightning disaster has become one of the important tasks of disaster prevention and mitigation.In this paper,based on the characteristics of lightning weather in Ulanqab City,the impact of lightning disaster on the city was analyzed,and lightning protection measures,such as strengthening supervision of lightning protection safety,establishing a long-term lightning protection mechanism,doing a good job in lightning protection construction and detection in key places,and further improving public awareness of lightning protection,were put forward to reduce and avoid urban lightning disasters as much as possible and ensure urban safety.
基金National Natural Science Foundation of China(51708004)Beijing Youth Teaching Elite Team Construction Project(108051360023XN261)North China University of Technology Yuyou Talent Training Program(215051360020XN160/009).
文摘With the continuous promotion of the construction of child friendly cities,the school commuting space is an important component of the construction of child friendly roads.Based on the background of child friendly cities,the commuting space of 11 primary and secondary schools in Bajiao Street is analyzed through literature analysis and field research methods.Firstly,the relevant literature on school commuting space is sorted out,and the characteristics of school commuting space are summarized,including transportation,landscape,culture,leisure,and security.Secondly,the characteristics of commuting space of primary and secondary schools in Bajiao Street are analyzed from three aspects:in front of the school gate,path space,and node space.This paper aims to provide reference and guidance for the future construction of children’s walking school commuting and promote the construction of a child friendly city.
基金supported by the Chongqing Social Science Planning Fund,China(2023BS034)the Science and Technology Project of Chongqing Jiaotong University,China(F1230069).
文摘Green transformation is an unavoidable choice for resource-based cities(RBCs)that face resource depletion and environmental pollution.Existing research has focused primarily on specific RBCs,making it challenging to apply green transformation strategies universally across cities.The fuzzy set qualitative comparative analysis(fsQCA)is a combination of qualitative and quantitative analyses that can handle multiple concurrent causality problems and determine how different conditions combine into configurations and generate an outcome.Thus,to address this gap,in this study,we established a research framework for green transformation and utilized the fsQCA to examine the configurations of 113 RBCs in China.By incorporating the element of time,this study explored the dynamic evolution of solutions in 2013,2016,and 2019.The main findings indicate that individual elements do not constitute the necessary conditions for improving the green transformation efficiency(GTE),and the systematic combination of multiple conditions is an effective path for realizing the improvement of the GTE in RBCs.Green transformation paths of RBCs exhibit the same destination through different paths.Additionally,the combination of system environment elements and system structure elements is both complementary and alternative.Differences in RBCs have led to various factor combinations and development paths,but there are some similarities in the key elements of the factor combinations at different stages.Economic environment,government support,and technological innovation are key factors that universally enhance the GTE in RBCs.These insights can assist city managers in formulating policies to drive green transformation and contribute to a better theoretical understanding of green transformation paths in RBCs.
文摘Digital technology provides a method of quantitative investigation and data analysis for contemporary landscape spatial analysis,and related research is moving from image recognition to digital algorithmic analysis,providing a more scientific and macroscopic way of research.The key to refinement design is to refine the spatial design process and the spatial improvement strategy system.Taking the ancient city of Zhaoyu in Qixian County,Shanxi Province as an example,(1)based on obtaining the integrated data of the ancient city through the drone tilt photography,the style and landscape of the ancient city are modeled;(2)the point cloud data with spatial information is imported into the point cloud analysis platform and the data analysis is carried out from the overall macroscopic style of the ancient city to the refinement level,which results in the formation of a more intuitive landscape design scheme,thus improving the precision and practicability of the landscape design;(3)Based on spatial big data,it starts from the spatial aggregation level,spatial distribution characteristics and other evaluation index system to achieve the refinement analysis of the site.Digital technology and methods are used throughout the process to explore the refined design path.
基金The Sichuan Medical and Health Care Promotion Institute Research Project(KY2022SJ0100).
文摘Background:Helicobacter pylori(HP)is associated with several gastrointestinal diseases,including peptic ulcer diseases and gastric cancer,and non-gastrointestinal diseases such as hypertension and Alzheimer's disease.However,the relationship between HP and lipid metabolism and atherosclerosis remains unclear.This study aims to investigate the association between H.pylori infection and high-density lipoprotein cholesterol levels and pulse wave conduction velocity.Methods:This is a report of a cross-sectional study that collected data from 2,827 participants.The data collected included results of life questionnaires,laboratory tests,13C-urea breath test(13C-UBT),and pulse wave conduction velocity test.Based on the results of the 13C-UBT test,the subjects were divided into two groups:the HP-uninfected group(HP−)and the HP-infected group(HP+).The study compared the differences in HDL-C levels and brachial-ankle pulse wave velocity(baPWV)between the two groups.One-way regression analysis was used to identify potential factors affecting HDL-C levels in the study population.Multiple regression equations were presented to analyze whether HP infection was an independent risk factor for abnormal HDL-C metabolism in the population.Results:Univariate analysis demonstrated that high-density lipoprotein cholesterol(HDL-C)levels were significantly lower in the HP+group compared to the HP−group,with a mean difference ofβ=−18.1 mg/dl(95%CI:−19.3 to−17.0,P<0.001).After adjusting for all variables,the HDL-C levels remained lower in the HP+group compared to the HP-group,with a mean difference ofβ=−17.4 mg/dl(95%CI:−18.2 to−16.7,P<0.001).These findings suggest that H.pylori infection is independently associated with abnormal HDL-C metabolism.Additionally,brachial-ankle pulse wave velocity(baPWV)was higher in the HP+group than in the HP−group on both sides.On the right side,the baPWV was 1,713.4±231.4 cm/s in the HP+group compared to 1,542.8±237.5 cm/s in the HP−group(t=−18.30,P<0.001).On the left side,the baPWV was 1,743.7±238.8 cm/s in the HP+group compared to 1,562.8±256.3 cm/s in the HP−group(t=−18.23,P<0.001).These results indicate a significant association between H.pylori infection and increased arterial stiffness,as measured by baPWV.Conclusion:Helicobacter pylori infection is associated with a decrease in high-density lipoprotein cholesterol levels and an increase in pulse wave conduction velocity.
文摘With the development of society,more and more cities are participating in the initiative to build learning cities.Constructing an evaluation indicator system for learning cities to monitor the progress and promote their growth has become increasingly important.This paper analyzes the preliminary framework of the UNESCO Global Learning City Index and R3L+Quality Framework.The comparison is made from the aspects of design philosophy,criteria of indicator,and the cycle of evaluation process.The findings suggest that the construction of an evaluation indicator system should be focused more on the diversity of learning city development,the construction of an evaluation process cycle,and the significance of building cooperative networks.