In this experimental study, involving deuterium–deuterium fusion neutron emission spectroscopy measurement on the experimental advanced superconducting tokamak(EAST), a liquid scintillator detector(BC501 A) was emplo...In this experimental study, involving deuterium–deuterium fusion neutron emission spectroscopy measurement on the experimental advanced superconducting tokamak(EAST), a liquid scintillator detector(BC501 A) was employed. This decision was based on the detector's superior sensitivity, optimal time-response, and its exceptional n–γ discrimination capability. This detector emits fast pulse signals that are as narrow as 100 ns, with high count rates that can peak at several Mcps. However, conventional nuclear circuits faced challenges in performing pulse height analysis, n–γ pulse shape discrimination, and in recording the entire pulse waveform under such high count rate conditions. To address these challenges, a high-speed digital pulse signal acquisition and processing system was designed. The system was developed around a micro-telecommunications computing architecture. Within this structure, a signal acquisition and processing(SAQP) module communicated through PCI Express links, achieving a bandwidth of up to 1.6 GB/s. To accurately capture the detailed shape of the pulses, four channels of analog-to-digital converters were used, each with a 500-MSPS sampling rate and a 14-bit resolution, ensuring an accuracy that surpassed 11 bits. An n–γ discrimination algorithm, based on the two-gate integral method, was also developed. Implemented within field programmable gate arrays, this algorithm provided a real-time n–γ discrimination spectrum for pulse height analysis. The system underwent rigorous testing in a laboratory setting and during an EAST experiment. The results confirmed that the innovative SAQP system can satisfy the demanding requirements of high-parameter experiments, manage count rates of up to 2 Mcps, execute real-time n–γ discrimination algorithms, and record entire pulse waveforms without any data loss.展开更多
The vehicle-track-bridge(VTB)element was used to investigate how a high-speed railway bridge reacted when it was subjected to near-fault directivity pulse-like ground motions.Based on the PEER NAG Strong Ground Motion...The vehicle-track-bridge(VTB)element was used to investigate how a high-speed railway bridge reacted when it was subjected to near-fault directivity pulse-like ground motions.Based on the PEER NAG Strong Ground Motion Database,the spatial analysis model of a vehicle-bridge system was developed,the VTB element was derived to simulate the interaction of train and bridge,and the elasto-plastic seismic responses of the bridge were calculated.The calculation results show that girder and pier top displacement,and bending moment of the pier base increase subjected to near-fault directivity pulse-like ground motion compared to far-field earthquakes,and the greater deformation responses in near-fault shaking are associated with fewer reversed cycles of loading.The hysteretic characteristics of the pier subjected to a near-fault directivity pulse-like earthquake should be explicitly expressed as the bending moment-rotation relationship of the pier base,which is characterized by the centrally strengthened hysteretic cycles at some point of the loading time-history curve.The results show that there is an amplification of the vertical deflection in the girder's mid-span owing to the high vertical ground motion.In light of these findings,the effect of the vertical ground motion should be used to adjust the unconservative amplification constant 2/3 of the vertical-to-horizontal peak ground motion ratio in the seismic design of bridge.展开更多
In order to study how welding parameters affect welding quality and droplet transfer, a synchronous acquisition and analysis system is established to acquire and analyze electrical signal and instantaneous images of d...In order to study how welding parameters affect welding quality and droplet transfer, a synchronous acquisition and analysis system is established to acquire and analyze electrical signal and instantaneous images of droplet transfer simultaneously, which is based on a self-developed soft-switching inverter. On the one hand, welding current and voltage signals are acquired and analyzed by a self-developed dynamic wavelet analyzer. On the other hand, images are filtered and optimized after they are captured by high-speed camera. The results show that instantaneous waveforms and statistical data of electrical signal contribute to make an overall assessment of welding quality, and that optimized high-speed images allow a visual and clear observation of droplet transfer process. The analysis of both waveforms and images leads to a further research on droplet transfer mechanism and provides a basis for precise control of droplet transfer.展开更多
BACKGROUND Cardiogenic shock (CS) secondary to acute myocardial infarction (AMI) complicates management of the condition, and often leads to poor prognosis. Prompt and accurate monitoring of cardiovascular and accompa...BACKGROUND Cardiogenic shock (CS) secondary to acute myocardial infarction (AMI) complicates management of the condition, and often leads to poor prognosis. Prompt and accurate monitoring of cardiovascular and accompanying hemodynamic changes is crucial in achieving adequate management of the condition. Advances in technology has availed procedures such as pulse index continuous cardiac output (PiCCO), which can offer precise monitoring of cardiovascular functions and hemodynamic parameters. In this study, PiCCO is evaluated for its potential utility in improving management and clinical outcomes among elderly patients with AMI complicated by CS. AIM To assess whether use of the PiCCO system can improve clinical outcomes in elderly patients with AMI complicated by CS.METHODS Patients from emergency intensive care units (EICU) or coronary care units (CCU) were randomized to receive PiCCO monitoring or not. The APACHE II score, SOFA score, hs-TnI, NT-proBNP, PaO2/FiO2 ratio and lactate levels on day 1, 3 and 7 after treatment were compared. The infusion and urine volume at 0-24 h, 24-48 h and 48-72 h were recorded, as were the cardiac index (CI), extravascular lung water index (EVLWI), intrathoracic blood volume index (ITBVI) and global end diastolic volume index (GEDVI) at similar time intervals. RESULTS Sixty patients with AMI complicated by CS were included in the study. The PiCCO group had a significantly lower APACHE II score, SOFA score, hs-TnI and NT-proBNP levels on day 1, 3 and 7 after treatment. The infusion and urine volume during 0-24 h in the PiCCO group were significantly greater, and this group also showed significantly higher ADL scores. Furthermore, the PiCCO group spent lesser days on vasoactive agents, mechanical ventilation, and had a reduced length of stay in EICU/CCU. Additionally, the CI was significantly higher at 48 h and 72 h in the PiCCO group compared with that at 24 h, and the EVLWI, ITBVI and GEDVI were significantly decreased at 48 h and 72 h. CONCLUSION Applying the PiCCO system could improve the clinical outcomes of elderly patients with AMI complicated by CS.展开更多
BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental therapy.Traditionally,parameters such as vital signs,central venous pressure,and urine out...BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental therapy.Traditionally,parameters such as vital signs,central venous pressure,and urine output have been used to estimate intravascular volume.Recently,pulse pressure variation(PPV)and non-invasive cardiac monitoring devices have been introduced.In this case report,we introduce a patient with massive active bleeding from giant renal angiomyolipoma(AML).During emergent nephrectomy,we used non-invasive cardiac monitoring with CSN-1901(Nihon Kohden,Tokyo,Japan)and PPV to evaluate the patient's intravascular volume status to achieve optimal fluid management.CASE SUMMARY A 30-year-old male patient with giant AML with active bleeding was referred to the emergency room complaining of severe abdominal pain and spontaneous abdominal distension.AML was diagnosed by computed tomography,and emergent nephrectomy was scheduled.Massive bleeding was expected so we decided to use non-invasive cardiac monitoring and PPV to assist fluid therapy because they are relatively easy and fast compared to invasive cardiac monitoring.During the surgery,6000 mL of estimated blood loss occurred.Along with the patient's vital signs and laboratory results,we monitored cardiac output,cardiac output,stroke volume,stroke volume index with a non-invasive cardiac monitoring device,and PPV using an intra-arterial catheter to evaluate intravascular volume status of the patient to compensate for massive bleeding.CONCLUSION In addition to traditional parameters,non-invasive cardiac monitoring and PPV are useful methods to evaluate patient's intravascular volume status and provideguidance for intraoperative management of hypovolemic shock patients.展开更多
<strong>Background</strong><strong>:</strong><b><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=&qu...<strong>Background</strong><strong>:</strong><b><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">Septic shock is a rapidly changing and fatal syndrome that can </span><span style="font-family:Verdana;">cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodynamics. PiCCO can accurately </span><span style="font-family:Verdana;">monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">To explore the application an</span><span style="font-family:Verdana;">d nursing of PiCCO in early fluid resuscitation in patie</span><span style="font-family:Verdana;">nts with septic shock. </span><b><span style="font-family:Verdana;">Me</span><span style="font-family:Verdana;">thods:</span></b><span style="font-family:Verdana;"> This was a retrospective observ</span><span style="font-family:Verdana;">ational study. The observation group and the control group each had 30 cases. The observation group used PiCCO to guide fluid resuscitation;the control group used conventional methods to guide fluid resuscitation.</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The changes in CVP, HR, MAP, and urine volume per hour were observed in the two groups. The changes of various indicators before and after fluid resuscitation, the length of stay in ICU and the mortality rate were compared between the two groups. All the outcomes were collected from the electronic medical case system after patients’ discharge from the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">APACHE </span></span><span style="font-family:Verdana;">II</span><span style="font-family:;" "=""><span style="font-family:Verdana;">, CVP, HR, MAP were compared between th</span><span style="font-family:Verdana;">e obse</span><span style="font-family:Verdana;">rvation group and th</span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">e control group, and the differences w</span><span><span style="font-family:Verdana;">ere statistically significant (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.05). The blood volume of patients in the observatio</span><span style="font-family:;" "=""><span style="font-family:Verdana;">n group was significantly improved after fluid supplementation</span><span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.05). Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was also significantly reduced</span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span><span> </span><span style="font-family:Verdana;"><</span><span> </span><span style="font-family:Verdana;">0.05</span><span><span style="font-family:Verdana;">). </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> PiCCO can be better used in early fluid resuscitation of patients with septic shock.</span></span>展开更多
Converters with pulse width modulation are used for connections between the direct current (DC) and alternating current (AC) networks, e.g., in uninterrupted power supply systems, AC electromotor drives, for power...Converters with pulse width modulation are used for connections between the direct current (DC) and alternating current (AC) networks, e.g., in uninterrupted power supply systems, AC electromotor drives, for powering induction furnaces, in audio technique. Spectrum of signals sampled by pulse amplitude modulation and output voltage spectrum of the converter with pulse width modulation have similar properties. Spectrum of signals sampled by pulse amplitude modulation contains a harmonic of frequency equal to the frequency of the modulating signal and the harmonics of frequencies equal to the sum of frequency of the modulating signal and multiples of the sampling frequency. The output voltage spectrum of the converter with bipolar pulse width modulation contains harmonic of frequency equal to the frequency of the modulating signal and harmonics of frequencies equal to sum of the frequency of the modulating signal and multiples of the frequency of the carrier signal. It also contains harmonics of frequencies equal to the sum of the multiples of the frequency of the modulating signal and the multiples of the carrier signal. The comparison analysis was carried out for the harmonics of the output voltage of the converter with bipolar pulse width modulation in time domain. The dependency of the amplitudes and frequency spectrum on the wave forms of the carrier signal and modulating signal was shown. Similarity of the output voltage spectrum of the converter and signal spectrum sampled by the pulse width modulation was also shown. Key words: Output voltage converter with bipolar pulse width modulation, spectral analysis, Fourier series, carrier signal, reference signal.展开更多
A novel circuit with a narrow pulse driving structure is proposed for enhancing the noise immunity and improving the performance of wide fan-in dynamic circuits. Also,an analytical mode that agrees well with simulatio...A novel circuit with a narrow pulse driving structure is proposed for enhancing the noise immunity and improving the performance of wide fan-in dynamic circuits. Also,an analytical mode that agrees well with simulations is presented for transistor sizing. Simulation results show that an improvement of up to 12% over the conventional technique at 1GHz is obtained with this circuit,which can run 1.6 times faster than the existing technique with the same noise immunity.展开更多
According to the signal processing characteristic of MIMO radars,an adaptive dwell scheduling algorithm is proposed.It is based on a novel pulse interleaving technique,which makes full use of transmitting,waiting and ...According to the signal processing characteristic of MIMO radars,an adaptive dwell scheduling algorithm is proposed.It is based on a novel pulse interleaving technique,which makes full use of transmitting,waiting and receiving durations of radar dwells.The utilization of transmitting duration is unique for MIMO radars and is realized through transmitting duration overlapping.Simulation results show that,compared with the conventional scheduling algorithm,the scheduling performance of MIMO radars can be improved effectively by the proposed algorithm,and the scheduling rule can be chosen arbitrarily when using the proposed algorithm.展开更多
Underwater pulsed discharge is widely applied in medicine, machining, and material modification.The induced cavitation bubble and subsequent cavitation collapse are considered the major motivations behind these applic...Underwater pulsed discharge is widely applied in medicine, machining, and material modification.The induced cavitation bubble and subsequent cavitation collapse are considered the major motivations behind these applications. This paper presents an underwater pulsed discharge system.The experimental setup is established to induce and investigate the cavitation bubble assisted with a high-speed camera. Three aspects, including the characteristic of the discharge with different applied voltages and conductivities, the evolution of the cavitation bubble profile, and the energy efficiency of cavitation bubble inducing, are investigated, respectively. Especially, the mechanism of pre-discharge time delay in the low field intensity case is explained using the Joule heat effect.The results show the validity of the underwater pulsed discharger and experimental setup. The present underwater pulsed discharger is proved to be a simple, portable, and easy-to-implement device for the investigation of cavitation bubble dynamics.展开更多
Dynamic responses of a carriage under excitation with the German high-speed low-interference track spectrum together with the air pressure pulse generated as high-speed trains passing each other are investigated with ...Dynamic responses of a carriage under excitation with the German high-speed low-interference track spectrum together with the air pressure pulse generated as high-speed trains passing each other are investigated with a multi-body dynamics method.The variations of degrees of freedom(DOFs:horizontal movement,roll angle,and yaw angle),the lateral wheel-rail force,the derailment coefficient and the rate of wheel load reduction with time when two carriages meet in open air are obtained and compared with the results of a single train travelling at specifie speeds.Results show that the rate of wheel load reduction increases with the increase of train speed and meets some safety standard at a certain speed,but exceeding the value of the rate of wheel load reduction does not necessarily mean derailment.The evaluation standard of the rate of wheel load reduction is somewhat conservative and may be loosened.The pressure pulse has significan effects on the train DOFs,and the evaluations of these safety indexes are strongly suggested in practice.The pressure pulse has a limited effect on the derailment coefficien and the lateral wheel-rail force,and,thus,their further evaluations may be not necessary.展开更多
The state space average model and the large signal models of Pulse Skip Modulation (PSM) mode are given in this paper. Farther more, based on these models and simulations of PSM converter circuits, the analysis of t...The state space average model and the large signal models of Pulse Skip Modulation (PSM) mode are given in this paper. Farther more, based on these models and simulations of PSM converter circuits, the analysis of the characteristics of PSM converter is described in this paper, of which include efficiency, frequency spectrum analysis, output voltage ripple, response speed and interference rejection capability. Compared with PWM control mode, PSM converter has high efficiency, especially with fight loads, quick response, good interference rejection and good EMC characteristic. Improved PSM slightly, it could be a kind of good independent regulating mode during the whole operating process for a DC-DC converter. Finally, some experimental results are also presented in this paper.展开更多
Ablative pulsed plasma thrusters(APPTs)are considered as an attractive propulsion option for station-keeping and drag makeup purposes for mass-and power-limited satellites.In order to understand the physical mechanism...Ablative pulsed plasma thrusters(APPTs)are considered as an attractive propulsion option for station-keeping and drag makeup purposes for mass-and power-limited satellites.In order to understand the physical mechanism of APPTs,high-speed camera and optical emission spectroscopy are utilized to investigate the plasma characteristics including the spatial distribution and composition between the electrodes.The plume images and spectra at different times and positions are experimentally recorded,and the spatial distribution,composition,and trajectory of plasmas can be concluded through analyzing them.With the increase of the distance from the ablation surface,two clusters of plasmas near the anode and cathode meet downstream,and the species and density of plasmas tend to be uniform.展开更多
It is a complicated dynamic phenomenon when a transient pressure pulse is triggered by two high-speed trains passing each other in a tunnel. The air pressure pulse is a transient excitation to side wall of the car bod...It is a complicated dynamic phenomenon when a transient pressure pulse is triggered by two high-speed trains passing each other in a tunnel. The air pressure pulse is a transient excitation to side wall of the car body. It can stimulate almost all vibration modes of the car body and the correlated assemblies, cause serious aerodynamic noise, and have important impacts on car body distortion, train noise, and operation safety. This article analyzes the time- frequency characteristics and main parameters of field-measured the air pressure wave, and its relationship with the train velocity as well as the vibration of the car body. Cepstrum analysis concludes that in the process of the meeting, the air pressure wave in tunnel crossing is a multiplying pressure wave instead of a superposed wave. The pressure pulse during the meeting is non-symmetrical one featured with a sharp front, large amplitude, fluctuating central sec- tion, and less sharp tail. The pulse width is inversely proportional to the train speed. As the speed increases, the impulse amplitude is amplified, and the speed of pulse front is advanced.展开更多
基金supported by the Users with Excellence Program of the Hefei Science Center CAS (No. 2020HSC-UE012)the Comprehensive Research Facility for Fusion Technology Program of China (No. 2018-000052-73-01-001228)the Institute of Energy,Hefei Comprehensive National Science Center (Nos. 21KZS205, 21KZL401 and 22KZZ502)。
文摘In this experimental study, involving deuterium–deuterium fusion neutron emission spectroscopy measurement on the experimental advanced superconducting tokamak(EAST), a liquid scintillator detector(BC501 A) was employed. This decision was based on the detector's superior sensitivity, optimal time-response, and its exceptional n–γ discrimination capability. This detector emits fast pulse signals that are as narrow as 100 ns, with high count rates that can peak at several Mcps. However, conventional nuclear circuits faced challenges in performing pulse height analysis, n–γ pulse shape discrimination, and in recording the entire pulse waveform under such high count rate conditions. To address these challenges, a high-speed digital pulse signal acquisition and processing system was designed. The system was developed around a micro-telecommunications computing architecture. Within this structure, a signal acquisition and processing(SAQP) module communicated through PCI Express links, achieving a bandwidth of up to 1.6 GB/s. To accurately capture the detailed shape of the pulses, four channels of analog-to-digital converters were used, each with a 500-MSPS sampling rate and a 14-bit resolution, ensuring an accuracy that surpassed 11 bits. An n–γ discrimination algorithm, based on the two-gate integral method, was also developed. Implemented within field programmable gate arrays, this algorithm provided a real-time n–γ discrimination spectrum for pulse height analysis. The system underwent rigorous testing in a laboratory setting and during an EAST experiment. The results confirmed that the innovative SAQP system can satisfy the demanding requirements of high-parameter experiments, manage count rates of up to 2 Mcps, execute real-time n–γ discrimination algorithms, and record entire pulse waveforms without any data loss.
基金Project(2013CB036203)supported by the National Basic Research Program of ChinaProject(2013M530022)supported by China Postdoctoral Science Foundation+4 种基金Project(2013-K5-31)supported by Science and Technology Plan of Ministry of Housing and Urban-Rural Development of ChinaProject supported by High-level Scientific Research Foundation for the Introduction of Talent of Yangzhou University,ChinaProject supported by the Open Fund of the National Engineering Laboratory for High Speed Railway Construction,ChinaProject(IRT1296)supported by the Program for Changjiang Scholars and Innovative Research Team in University,ChinaProject(50908236)supported by the National Natural Science Foundation of China
文摘The vehicle-track-bridge(VTB)element was used to investigate how a high-speed railway bridge reacted when it was subjected to near-fault directivity pulse-like ground motions.Based on the PEER NAG Strong Ground Motion Database,the spatial analysis model of a vehicle-bridge system was developed,the VTB element was derived to simulate the interaction of train and bridge,and the elasto-plastic seismic responses of the bridge were calculated.The calculation results show that girder and pier top displacement,and bending moment of the pier base increase subjected to near-fault directivity pulse-like ground motion compared to far-field earthquakes,and the greater deformation responses in near-fault shaking are associated with fewer reversed cycles of loading.The hysteretic characteristics of the pier subjected to a near-fault directivity pulse-like earthquake should be explicitly expressed as the bending moment-rotation relationship of the pier base,which is characterized by the centrally strengthened hysteretic cycles at some point of the loading time-history curve.The results show that there is an amplification of the vertical deflection in the girder's mid-span owing to the high vertical ground motion.In light of these findings,the effect of the vertical ground motion should be used to adjust the unconservative amplification constant 2/3 of the vertical-to-horizontal peak ground motion ratio in the seismic design of bridge.
基金This work was supported by National Natural Science Foundation of China ( No. 50875088) Natural Science Foundation of Guangdong Province, China ( No. 07006479).
文摘In order to study how welding parameters affect welding quality and droplet transfer, a synchronous acquisition and analysis system is established to acquire and analyze electrical signal and instantaneous images of droplet transfer simultaneously, which is based on a self-developed soft-switching inverter. On the one hand, welding current and voltage signals are acquired and analyzed by a self-developed dynamic wavelet analyzer. On the other hand, images are filtered and optimized after they are captured by high-speed camera. The results show that instantaneous waveforms and statistical data of electrical signal contribute to make an overall assessment of welding quality, and that optimized high-speed images allow a visual and clear observation of droplet transfer process. The analysis of both waveforms and images leads to a further research on droplet transfer mechanism and provides a basis for precise control of droplet transfer.
文摘BACKGROUND Cardiogenic shock (CS) secondary to acute myocardial infarction (AMI) complicates management of the condition, and often leads to poor prognosis. Prompt and accurate monitoring of cardiovascular and accompanying hemodynamic changes is crucial in achieving adequate management of the condition. Advances in technology has availed procedures such as pulse index continuous cardiac output (PiCCO), which can offer precise monitoring of cardiovascular functions and hemodynamic parameters. In this study, PiCCO is evaluated for its potential utility in improving management and clinical outcomes among elderly patients with AMI complicated by CS. AIM To assess whether use of the PiCCO system can improve clinical outcomes in elderly patients with AMI complicated by CS.METHODS Patients from emergency intensive care units (EICU) or coronary care units (CCU) were randomized to receive PiCCO monitoring or not. The APACHE II score, SOFA score, hs-TnI, NT-proBNP, PaO2/FiO2 ratio and lactate levels on day 1, 3 and 7 after treatment were compared. The infusion and urine volume at 0-24 h, 24-48 h and 48-72 h were recorded, as were the cardiac index (CI), extravascular lung water index (EVLWI), intrathoracic blood volume index (ITBVI) and global end diastolic volume index (GEDVI) at similar time intervals. RESULTS Sixty patients with AMI complicated by CS were included in the study. The PiCCO group had a significantly lower APACHE II score, SOFA score, hs-TnI and NT-proBNP levels on day 1, 3 and 7 after treatment. The infusion and urine volume during 0-24 h in the PiCCO group were significantly greater, and this group also showed significantly higher ADL scores. Furthermore, the PiCCO group spent lesser days on vasoactive agents, mechanical ventilation, and had a reduced length of stay in EICU/CCU. Additionally, the CI was significantly higher at 48 h and 72 h in the PiCCO group compared with that at 24 h, and the EVLWI, ITBVI and GEDVI were significantly decreased at 48 h and 72 h. CONCLUSION Applying the PiCCO system could improve the clinical outcomes of elderly patients with AMI complicated by CS.
文摘BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental therapy.Traditionally,parameters such as vital signs,central venous pressure,and urine output have been used to estimate intravascular volume.Recently,pulse pressure variation(PPV)and non-invasive cardiac monitoring devices have been introduced.In this case report,we introduce a patient with massive active bleeding from giant renal angiomyolipoma(AML).During emergent nephrectomy,we used non-invasive cardiac monitoring with CSN-1901(Nihon Kohden,Tokyo,Japan)and PPV to evaluate the patient's intravascular volume status to achieve optimal fluid management.CASE SUMMARY A 30-year-old male patient with giant AML with active bleeding was referred to the emergency room complaining of severe abdominal pain and spontaneous abdominal distension.AML was diagnosed by computed tomography,and emergent nephrectomy was scheduled.Massive bleeding was expected so we decided to use non-invasive cardiac monitoring and PPV to assist fluid therapy because they are relatively easy and fast compared to invasive cardiac monitoring.During the surgery,6000 mL of estimated blood loss occurred.Along with the patient's vital signs and laboratory results,we monitored cardiac output,cardiac output,stroke volume,stroke volume index with a non-invasive cardiac monitoring device,and PPV using an intra-arterial catheter to evaluate intravascular volume status of the patient to compensate for massive bleeding.CONCLUSION In addition to traditional parameters,non-invasive cardiac monitoring and PPV are useful methods to evaluate patient's intravascular volume status and provideguidance for intraoperative management of hypovolemic shock patients.
文摘<strong>Background</strong><strong>:</strong><b><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">Septic shock is a rapidly changing and fatal syndrome that can </span><span style="font-family:Verdana;">cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodynamics. PiCCO can accurately </span><span style="font-family:Verdana;">monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. </span><b><span style="font-family:Verdana;">Objectives: </span></b><span style="font-family:Verdana;">To explore the application an</span><span style="font-family:Verdana;">d nursing of PiCCO in early fluid resuscitation in patie</span><span style="font-family:Verdana;">nts with septic shock. </span><b><span style="font-family:Verdana;">Me</span><span style="font-family:Verdana;">thods:</span></b><span style="font-family:Verdana;"> This was a retrospective observ</span><span style="font-family:Verdana;">ational study. The observation group and the control group each had 30 cases. The observation group used PiCCO to guide fluid resuscitation;the control group used conventional methods to guide fluid resuscitation.</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The changes in CVP, HR, MAP, and urine volume per hour were observed in the two groups. The changes of various indicators before and after fluid resuscitation, the length of stay in ICU and the mortality rate were compared between the two groups. All the outcomes were collected from the electronic medical case system after patients’ discharge from the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">APACHE </span></span><span style="font-family:Verdana;">II</span><span style="font-family:;" "=""><span style="font-family:Verdana;">, CVP, HR, MAP were compared between th</span><span style="font-family:Verdana;">e obse</span><span style="font-family:Verdana;">rvation group and th</span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">e control group, and the differences w</span><span><span style="font-family:Verdana;">ere statistically significant (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">0.05). The blood volume of patients in the observatio</span><span style="font-family:;" "=""><span style="font-family:Verdana;">n group was significantly improved after fluid supplementation</span><span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span></span><i><span style="font-family:;" "=""> </span></i><span style="font-family:Verdana;"><</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">0.05). Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was also significantly reduced</span><span style="font-family:Verdana;"> (</span><i><span style="font-family:Verdana;">P</span></i></span><span> </span><span style="font-family:Verdana;"><</span><span> </span><span style="font-family:Verdana;">0.05</span><span><span style="font-family:Verdana;">). </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> PiCCO can be better used in early fluid resuscitation of patients with septic shock.</span></span>
文摘Converters with pulse width modulation are used for connections between the direct current (DC) and alternating current (AC) networks, e.g., in uninterrupted power supply systems, AC electromotor drives, for powering induction furnaces, in audio technique. Spectrum of signals sampled by pulse amplitude modulation and output voltage spectrum of the converter with pulse width modulation have similar properties. Spectrum of signals sampled by pulse amplitude modulation contains a harmonic of frequency equal to the frequency of the modulating signal and the harmonics of frequencies equal to the sum of frequency of the modulating signal and multiples of the sampling frequency. The output voltage spectrum of the converter with bipolar pulse width modulation contains harmonic of frequency equal to the frequency of the modulating signal and harmonics of frequencies equal to sum of the frequency of the modulating signal and multiples of the frequency of the carrier signal. It also contains harmonics of frequencies equal to the sum of the multiples of the frequency of the modulating signal and the multiples of the carrier signal. The comparison analysis was carried out for the harmonics of the output voltage of the converter with bipolar pulse width modulation in time domain. The dependency of the amplitudes and frequency spectrum on the wave forms of the carrier signal and modulating signal was shown. Similarity of the output voltage spectrum of the converter and signal spectrum sampled by the pulse width modulation was also shown. Key words: Output voltage converter with bipolar pulse width modulation, spectral analysis, Fourier series, carrier signal, reference signal.
文摘A novel circuit with a narrow pulse driving structure is proposed for enhancing the noise immunity and improving the performance of wide fan-in dynamic circuits. Also,an analytical mode that agrees well with simulations is presented for transistor sizing. Simulation results show that an improvement of up to 12% over the conventional technique at 1GHz is obtained with this circuit,which can run 1.6 times faster than the existing technique with the same noise immunity.
基金supported by the National Natural Science Foundation of China(6110117161032010)
文摘According to the signal processing characteristic of MIMO radars,an adaptive dwell scheduling algorithm is proposed.It is based on a novel pulse interleaving technique,which makes full use of transmitting,waiting and receiving durations of radar dwells.The utilization of transmitting duration is unique for MIMO radars and is realized through transmitting duration overlapping.Simulation results show that,compared with the conventional scheduling algorithm,the scheduling performance of MIMO radars can be improved effectively by the proposed algorithm,and the scheduling rule can be chosen arbitrarily when using the proposed algorithm.
基金supported by National Natural Science Foundation of China (Grant Nos. 11874140, 11574072)National Key Research and Development Program of China (Grant No. 2016YFC0401600)+2 种基金Primary Research and Development Plan of Jiangsu Province, China (Grant No. BE2016056)Fundamental Research Funds for the Central Universities (Grant No. 2017B17814)Postgraduate Research & Practice Innovation Program of Jiangsu Province (Grant No. KYCX18_0552)
文摘Underwater pulsed discharge is widely applied in medicine, machining, and material modification.The induced cavitation bubble and subsequent cavitation collapse are considered the major motivations behind these applications. This paper presents an underwater pulsed discharge system.The experimental setup is established to induce and investigate the cavitation bubble assisted with a high-speed camera. Three aspects, including the characteristic of the discharge with different applied voltages and conductivities, the evolution of the cavitation bubble profile, and the energy efficiency of cavitation bubble inducing, are investigated, respectively. Especially, the mechanism of pre-discharge time delay in the low field intensity case is explained using the Joule heat effect.The results show the validity of the underwater pulsed discharger and experimental setup. The present underwater pulsed discharger is proved to be a simple, portable, and easy-to-implement device for the investigation of cavitation bubble dynamics.
基金the National Basic Research Program of China (973 program,Grant 2011CB711100)the National Natural Science Foundation of China (Project No.11372307)the Chinese Academy of Sciences (Grant KJCX2-EW-L03)
文摘Dynamic responses of a carriage under excitation with the German high-speed low-interference track spectrum together with the air pressure pulse generated as high-speed trains passing each other are investigated with a multi-body dynamics method.The variations of degrees of freedom(DOFs:horizontal movement,roll angle,and yaw angle),the lateral wheel-rail force,the derailment coefficient and the rate of wheel load reduction with time when two carriages meet in open air are obtained and compared with the results of a single train travelling at specifie speeds.Results show that the rate of wheel load reduction increases with the increase of train speed and meets some safety standard at a certain speed,but exceeding the value of the rate of wheel load reduction does not necessarily mean derailment.The evaluation standard of the rate of wheel load reduction is somewhat conservative and may be loosened.The pressure pulse has significan effects on the train DOFs,and the evaluations of these safety indexes are strongly suggested in practice.The pressure pulse has a limited effect on the derailment coefficien and the lateral wheel-rail force,and,thus,their further evaluations may be not necessary.
基金Supported by the National Natural Science Foundation of China (No.60436030)
文摘The state space average model and the large signal models of Pulse Skip Modulation (PSM) mode are given in this paper. Farther more, based on these models and simulations of PSM converter circuits, the analysis of the characteristics of PSM converter is described in this paper, of which include efficiency, frequency spectrum analysis, output voltage ripple, response speed and interference rejection capability. Compared with PWM control mode, PSM converter has high efficiency, especially with fight loads, quick response, good interference rejection and good EMC characteristic. Improved PSM slightly, it could be a kind of good independent regulating mode during the whole operating process for a DC-DC converter. Finally, some experimental results are also presented in this paper.
基金National Natural Science Foundation of China(No.11772354)for the financial assistance provided for this work。
文摘Ablative pulsed plasma thrusters(APPTs)are considered as an attractive propulsion option for station-keeping and drag makeup purposes for mass-and power-limited satellites.In order to understand the physical mechanism of APPTs,high-speed camera and optical emission spectroscopy are utilized to investigate the plasma characteristics including the spatial distribution and composition between the electrodes.The plume images and spectra at different times and positions are experimentally recorded,and the spatial distribution,composition,and trajectory of plasmas can be concluded through analyzing them.With the increase of the distance from the ablation surface,two clusters of plasmas near the anode and cathode meet downstream,and the species and density of plasmas tend to be uniform.
基金supported by the National Science and Technology Pillar Programs of China (No.2009BAG12A01-E02,No. 2009BAG12A01-E03 and No. 2009BAG12A01-E04)
文摘It is a complicated dynamic phenomenon when a transient pressure pulse is triggered by two high-speed trains passing each other in a tunnel. The air pressure pulse is a transient excitation to side wall of the car body. It can stimulate almost all vibration modes of the car body and the correlated assemblies, cause serious aerodynamic noise, and have important impacts on car body distortion, train noise, and operation safety. This article analyzes the time- frequency characteristics and main parameters of field-measured the air pressure wave, and its relationship with the train velocity as well as the vibration of the car body. Cepstrum analysis concludes that in the process of the meeting, the air pressure wave in tunnel crossing is a multiplying pressure wave instead of a superposed wave. The pressure pulse during the meeting is non-symmetrical one featured with a sharp front, large amplitude, fluctuating central sec- tion, and less sharp tail. The pulse width is inversely proportional to the train speed. As the speed increases, the impulse amplitude is amplified, and the speed of pulse front is advanced.