Cationic polymer drilling fluid (CPDF) is a new water base drilling fluid in which high molecular weight (HMW) cationic polymer (CPAM) is an encapsulating and flocculating agent and organic quaternary ammonium compoun...Cationic polymer drilling fluid (CPDF) is a new water base drilling fluid in which high molecular weight (HMW) cationic polymer (CPAM) is an encapsulating and flocculating agent and organic quaternary ammonium compound (NW-1) acts as shale inhibitor. This paper describes the experimental results of cuttings recovery, particle size distribution layer spacing and Zeta potential, and discusses the inhibition of CPDF system and its major additives. The advantages of CPDF will be proved by its application in well LX-2.展开更多
The low signal-to-noise ratio(S/N)and single functionality of fluorescence imaging agents have limited their practical applications.Bright two-photon excitation(2PE)imaging probes are highly desirable in vivo with lar...The low signal-to-noise ratio(S/N)and single functionality of fluorescence imaging agents have limited their practical applications.Bright two-photon excitation(2PE)imaging probes are highly desirable in vivo with larger imaging depth,minor autofluorescence background,and less photodamage.Herein,we developed responsive aggregated gold nanoparticles(Au NPs)as high contrast 2PE imaging agents,capable of emitting red fluorescence upon excitation of near-infrared(NIR)laser and possessing a high signal-to-noise ratio(S/N of 2,475).By forming aggregates in situ inside tumor tissue,doxorubicin hydrochloride(DOX)-loaded mix-charged gold nanoparticles(DOX-MC-Au NPs)were utilized to act as selective fluorescence imaging probes and precise therapy agents.These high-contrast theranostic agents offer a promising potential for precise cancer imaging and therapy,which might open a new venue to multifunctional and noninvasive theranostics.展开更多
文摘Cationic polymer drilling fluid (CPDF) is a new water base drilling fluid in which high molecular weight (HMW) cationic polymer (CPAM) is an encapsulating and flocculating agent and organic quaternary ammonium compound (NW-1) acts as shale inhibitor. This paper describes the experimental results of cuttings recovery, particle size distribution layer spacing and Zeta potential, and discusses the inhibition of CPDF system and its major additives. The advantages of CPDF will be proved by its application in well LX-2.
基金supported by the Science and Technology Project of Jiangsu Province(BZ2022056)the Ministry of Education,Singapore(Tier 1 A-8000013-00-00)。
文摘The low signal-to-noise ratio(S/N)and single functionality of fluorescence imaging agents have limited their practical applications.Bright two-photon excitation(2PE)imaging probes are highly desirable in vivo with larger imaging depth,minor autofluorescence background,and less photodamage.Herein,we developed responsive aggregated gold nanoparticles(Au NPs)as high contrast 2PE imaging agents,capable of emitting red fluorescence upon excitation of near-infrared(NIR)laser and possessing a high signal-to-noise ratio(S/N of 2,475).By forming aggregates in situ inside tumor tissue,doxorubicin hydrochloride(DOX)-loaded mix-charged gold nanoparticles(DOX-MC-Au NPs)were utilized to act as selective fluorescence imaging probes and precise therapy agents.These high-contrast theranostic agents offer a promising potential for precise cancer imaging and therapy,which might open a new venue to multifunctional and noninvasive theranostics.
