<strong>Objective</strong><span style="font-family:;" "=""><strong>:</strong> To observe extrinsic foot muscle activity ratio and sensory disturbance in Leprosy a...<strong>Objective</strong><span style="font-family:;" "=""><strong>:</strong> To observe extrinsic foot muscle activity ratio and sensory disturbance in Leprosy and its implication to foot deformity and walking capacity. <b>Design: </b>Cross sectional study in Singkawang, West Kalimantan. <b>Materials and Methods</b>: Thirty-three leprosy patients without walking aids and/or orthotic prosthetic were enrolled using consecutive sampling. Foot deformity score was calculated and muscle<span style="color:red;"> </span>activity w</span><span style="font-family:;" "="">as</span><span style="font-family:;" "=""> measured using surface EMG. Muscle activation ratio was calculated in Tibialis anterior-to-Gastrocnemius (TA/GA) and Tibialis Anterior-to-Peroneal (TA/PE). Walking capacity was assessed using Timed up and Go test.<b> Results</b>: Significant differences of foot ulcer (p = 0.001) and foot deformities (p = 0.001) were found in plantar sensory deficit group. There was strong correlation between foot deformities and decreased TA/GA ratio (p = 0.001, r = <span style="white-space:nowrap;">﹣</span>0.787) and decreased TA/PE ratio (p = 0.001, r = <span style="white-space:nowrap;">﹣</span>0.663). There were significant differences of TA/GA ratio (p = 0.00) and TA/PE ratio (p = 0.09) based on the foot ulcer, and no significant <span>difference of Timed Up and Go Test result within plantar sensory deficit </span>group (p = 0.427). No significant correlation was found between walking capacity and TA/GA ratio (p = 0.055), and TA/PE ratio (p = 0.165). <b>Conclusion</b>: Plantar sensory deficit and decreased extrinsic muscle activation ratio during gait had been proven to affect foot impairment, but have not been proven to inhibit walking capacity.</span>展开更多
AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six...AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis.展开更多
Background: Chronic heart failure is a public health problem worldwide. It has a high mortality rate and is accompanied by a decreased functional capacity and alteration of the quality of life. Objective: This st...Background: Chronic heart failure is a public health problem worldwide. It has a high mortality rate and is accompanied by a decreased functional capacity and alteration of the quality of life. Objective: This study aimed to assess the cardiovascular functional capacity of a group of patients suffering from heart failure using the 6-minute walk test (6 MWT). Methods: This was a cross-sectional study carried out in the cardiology unit of Douala’s general hospital for 4 months. We included all eligible patients aged 18 years or more who had stable chronic heart failure and gave informed consent. Those who had an acute coronary syndrome (≤1 month), tachycardia (HR ≥ 120 bpm), high blood pressure (SBP ≥ 180 mmHg and/or DBP ≥ 100 mmHg) and reduced mobility due to orthopaedic reasons were excluded. A 6 MWT was done according to the American Thoracic Society guidelines. The 6 MWT result was considered poor for - 450 m and good for >450 m. Results: We recruited a total of 81 patients (61.7% women) with a mean age of 65.9 ± 10.6 years. The most frequent risk factor for heart failure was high blood pressure (77.8%), alcohol consumption(69.1%) and a sedentary lifestyle (53.1%). The left ventricular ejection fraction was mostly preserved (42.0%) or mildly altered (46.9). The 6 MWT results were poor in 55.6% of cases, average in 19.8% of cases and good in only 24.7% of cases. More than half (59.3%) of the participants perceived the effort as being difficult. The cardiovascular functional capacity was significantly associated with age, heart failure stage and physical activity (p Conclusion: Most patients suffering from chronic stable heart failure in the general hospital of Douala have poor cardiovascular functional capacity.展开更多
Background: Venous thromboembolism (VTE) is among the leading causes of hospital-related disability-adjusted life years lost. We aimed to determine the prevalence and determinants of functional capacity impairment six...Background: Venous thromboembolism (VTE) is among the leading causes of hospital-related disability-adjusted life years lost. We aimed to determine the prevalence and determinants of functional capacity impairment six to twelve months after an acute VTE event. Methods: This was a cross-sectional study conducted between January and April 2021 in two referral hospitals of Yaoundé, including consenting adult patients admitted to these hospitals six to twelve months ago for VTE. We excluded dead patients and those with any comorbidity or symptoms limiting physical activity. The functional outcome was assessed with the six-minute walk test. Functional capacity impairment was defined as walking distance lower than the expected value. Results: We included 27 cases in this study with a mean age of 53.2 ± 14.4 years. The prevalence of functional capacity impairment was 29.6% (95% CI: 14.8 - 48.1). Factors associated with poor functional outcome were obesity (OR: 59.5;95% CI: 4.6 - 767.2;p - 207.4;p = 0.017), massive PE (OR: 30;95% CI: 2.5 - 354;p = 0.004), and poor adherence to treatment (OR: 30.3;95% CI: 2.5 - 333.3;p = 0.004). Conclusion: Functional capacity impairment is common in the medium-term after VTE and factors associated with this poor outcome are obesity, the severity of the VTE, and poor adherence to treatment.展开更多
Background: The 6-minute walk test (6TC) was initially used as an instrument for assessing physical and cardiorespiratory capacity, but is currently being used to monitor treatments, and compare physical interventions...Background: The 6-minute walk test (6TC) was initially used as an instrument for assessing physical and cardiorespiratory capacity, but is currently being used to monitor treatments, and compare physical interventions and prognostic evaluation. Although already recognized as a research method in several specialties, 6TC has not been used in rheumatology. Patients with rheumatoid arthritis (RA) may have impaired functional capacity as well as increased cardiovascular mortality. An adequate functional evaluation of these patients is necessary and the 6TC may be useful in this sense. Objective: The aim of this study was to perform the 6-minute walk test in RA patients and to compare the performance with a control group. Method: A cross-sectional study was carried out in which the sample consisted of 85 women, 46 patients with rheumatoid arthritis and 39 healthy controls. A descriptive analysis of the data was performed. One-Way ANOVA methodology was used to compare the patient and control groups followed by the graphic analysis. Results: The distance walked on the 6TC by RA patients was on average 522.2 meters. In the distance control group found in the 6TC was on average 628.8 meters, the difference being statistically significant. Conclusion: In this study the distance covered in 6TC by women with RA was lower than that of healthy women of the same age.展开更多
The tripod foundation(TF)is a prevalent foundation configuration in contemporary engineering practices.In comparison to a single pile,TF comprised interconnected individual piles,resulting in enhanced bearing capacity...The tripod foundation(TF)is a prevalent foundation configuration in contemporary engineering practices.In comparison to a single pile,TF comprised interconnected individual piles,resulting in enhanced bearing capacity and stability.A physical model test was conducted within a sandy soil foundation,systematically varying the length-to-diameter ratio of the TF.The investigation aimed to comprehend the impact of altering the height of the central bucket on the historical horizontal bearing capacity of the foundation in saturated sand.Additionally,the study scrutinized the historical consequences of soil pressure and pore water pressure surrounding the bucket throughout the loading process.The historical findings revealed a significant enhancement in the horizontal bearing capacity of the TF under undrained conditions.When subjected to a historical horizontal loading angle of 0°for a single pile,the multi-bucket foundation exhibited superior historical bearing capacity compared to a single-pile foundation experiencing a historical loading angle of 180°under pulling conditions.With each historical increment in bucket height from 150 mm to 350 mm in 100 mm intervals,the historical horizontal bearing capacity of the TF exhibited an approximately 75%increase relative to the 150 mm bucket height,indicating a proportional relationship.Importantly,the historical internal pore water pressure within the bucket foundation remained unaffected by drainage conditions during loading.Conversely,undrained conditions led to a historical elevation in pore water pressure at the lower side of the pressure bucket.Consequently,in practical engineering applications,the optimization of the historical bearing efficacy of the TF necessitated the historical closure of the valve atop the foundation to sustain internal negative pressure within the bucket.This historical measure served to augment the historical horizontal bearing capacity.Simultaneously,historical external loads,such as wind,waves,and currents,were directed towards any individual bucket within the TF for optimal historical performance.展开更多
文摘<strong>Objective</strong><span style="font-family:;" "=""><strong>:</strong> To observe extrinsic foot muscle activity ratio and sensory disturbance in Leprosy and its implication to foot deformity and walking capacity. <b>Design: </b>Cross sectional study in Singkawang, West Kalimantan. <b>Materials and Methods</b>: Thirty-three leprosy patients without walking aids and/or orthotic prosthetic were enrolled using consecutive sampling. Foot deformity score was calculated and muscle<span style="color:red;"> </span>activity w</span><span style="font-family:;" "="">as</span><span style="font-family:;" "=""> measured using surface EMG. Muscle activation ratio was calculated in Tibialis anterior-to-Gastrocnemius (TA/GA) and Tibialis Anterior-to-Peroneal (TA/PE). Walking capacity was assessed using Timed up and Go test.<b> Results</b>: Significant differences of foot ulcer (p = 0.001) and foot deformities (p = 0.001) were found in plantar sensory deficit group. There was strong correlation between foot deformities and decreased TA/GA ratio (p = 0.001, r = <span style="white-space:nowrap;">﹣</span>0.787) and decreased TA/PE ratio (p = 0.001, r = <span style="white-space:nowrap;">﹣</span>0.663). There were significant differences of TA/GA ratio (p = 0.00) and TA/PE ratio (p = 0.09) based on the foot ulcer, and no significant <span>difference of Timed Up and Go Test result within plantar sensory deficit </span>group (p = 0.427). No significant correlation was found between walking capacity and TA/GA ratio (p = 0.055), and TA/PE ratio (p = 0.165). <b>Conclusion</b>: Plantar sensory deficit and decreased extrinsic muscle activation ratio during gait had been proven to affect foot impairment, but have not been proven to inhibit walking capacity.</span>
文摘AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis.
文摘Background: Chronic heart failure is a public health problem worldwide. It has a high mortality rate and is accompanied by a decreased functional capacity and alteration of the quality of life. Objective: This study aimed to assess the cardiovascular functional capacity of a group of patients suffering from heart failure using the 6-minute walk test (6 MWT). Methods: This was a cross-sectional study carried out in the cardiology unit of Douala’s general hospital for 4 months. We included all eligible patients aged 18 years or more who had stable chronic heart failure and gave informed consent. Those who had an acute coronary syndrome (≤1 month), tachycardia (HR ≥ 120 bpm), high blood pressure (SBP ≥ 180 mmHg and/or DBP ≥ 100 mmHg) and reduced mobility due to orthopaedic reasons were excluded. A 6 MWT was done according to the American Thoracic Society guidelines. The 6 MWT result was considered poor for - 450 m and good for >450 m. Results: We recruited a total of 81 patients (61.7% women) with a mean age of 65.9 ± 10.6 years. The most frequent risk factor for heart failure was high blood pressure (77.8%), alcohol consumption(69.1%) and a sedentary lifestyle (53.1%). The left ventricular ejection fraction was mostly preserved (42.0%) or mildly altered (46.9). The 6 MWT results were poor in 55.6% of cases, average in 19.8% of cases and good in only 24.7% of cases. More than half (59.3%) of the participants perceived the effort as being difficult. The cardiovascular functional capacity was significantly associated with age, heart failure stage and physical activity (p Conclusion: Most patients suffering from chronic stable heart failure in the general hospital of Douala have poor cardiovascular functional capacity.
文摘Background: Venous thromboembolism (VTE) is among the leading causes of hospital-related disability-adjusted life years lost. We aimed to determine the prevalence and determinants of functional capacity impairment six to twelve months after an acute VTE event. Methods: This was a cross-sectional study conducted between January and April 2021 in two referral hospitals of Yaoundé, including consenting adult patients admitted to these hospitals six to twelve months ago for VTE. We excluded dead patients and those with any comorbidity or symptoms limiting physical activity. The functional outcome was assessed with the six-minute walk test. Functional capacity impairment was defined as walking distance lower than the expected value. Results: We included 27 cases in this study with a mean age of 53.2 ± 14.4 years. The prevalence of functional capacity impairment was 29.6% (95% CI: 14.8 - 48.1). Factors associated with poor functional outcome were obesity (OR: 59.5;95% CI: 4.6 - 767.2;p - 207.4;p = 0.017), massive PE (OR: 30;95% CI: 2.5 - 354;p = 0.004), and poor adherence to treatment (OR: 30.3;95% CI: 2.5 - 333.3;p = 0.004). Conclusion: Functional capacity impairment is common in the medium-term after VTE and factors associated with this poor outcome are obesity, the severity of the VTE, and poor adherence to treatment.
文摘Background: The 6-minute walk test (6TC) was initially used as an instrument for assessing physical and cardiorespiratory capacity, but is currently being used to monitor treatments, and compare physical interventions and prognostic evaluation. Although already recognized as a research method in several specialties, 6TC has not been used in rheumatology. Patients with rheumatoid arthritis (RA) may have impaired functional capacity as well as increased cardiovascular mortality. An adequate functional evaluation of these patients is necessary and the 6TC may be useful in this sense. Objective: The aim of this study was to perform the 6-minute walk test in RA patients and to compare the performance with a control group. Method: A cross-sectional study was carried out in which the sample consisted of 85 women, 46 patients with rheumatoid arthritis and 39 healthy controls. A descriptive analysis of the data was performed. One-Way ANOVA methodology was used to compare the patient and control groups followed by the graphic analysis. Results: The distance walked on the 6TC by RA patients was on average 522.2 meters. In the distance control group found in the 6TC was on average 628.8 meters, the difference being statistically significant. Conclusion: In this study the distance covered in 6TC by women with RA was lower than that of healthy women of the same age.
文摘The tripod foundation(TF)is a prevalent foundation configuration in contemporary engineering practices.In comparison to a single pile,TF comprised interconnected individual piles,resulting in enhanced bearing capacity and stability.A physical model test was conducted within a sandy soil foundation,systematically varying the length-to-diameter ratio of the TF.The investigation aimed to comprehend the impact of altering the height of the central bucket on the historical horizontal bearing capacity of the foundation in saturated sand.Additionally,the study scrutinized the historical consequences of soil pressure and pore water pressure surrounding the bucket throughout the loading process.The historical findings revealed a significant enhancement in the horizontal bearing capacity of the TF under undrained conditions.When subjected to a historical horizontal loading angle of 0°for a single pile,the multi-bucket foundation exhibited superior historical bearing capacity compared to a single-pile foundation experiencing a historical loading angle of 180°under pulling conditions.With each historical increment in bucket height from 150 mm to 350 mm in 100 mm intervals,the historical horizontal bearing capacity of the TF exhibited an approximately 75%increase relative to the 150 mm bucket height,indicating a proportional relationship.Importantly,the historical internal pore water pressure within the bucket foundation remained unaffected by drainage conditions during loading.Conversely,undrained conditions led to a historical elevation in pore water pressure at the lower side of the pressure bucket.Consequently,in practical engineering applications,the optimization of the historical bearing efficacy of the TF necessitated the historical closure of the valve atop the foundation to sustain internal negative pressure within the bucket.This historical measure served to augment the historical horizontal bearing capacity.Simultaneously,historical external loads,such as wind,waves,and currents,were directed towards any individual bucket within the TF for optimal historical performance.
