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Ghost-YOLO v8:An Attention-Guided Enhanced Small Target Detection Algorithm for Floating Litter on Water Surfaces
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作者 Zhongmin Huangfu Shuqing Li Luoheng Yan 《Computers, Materials & Continua》 SCIE EI 2024年第9期3713-3731,共19页
Addressing the challenges in detecting surface floating litter in artificial lakes,including complex environments,uneven illumination,and susceptibility to noise andweather,this paper proposes an efficient and lightwe... Addressing the challenges in detecting surface floating litter in artificial lakes,including complex environments,uneven illumination,and susceptibility to noise andweather,this paper proposes an efficient and lightweight Ghost-YOLO(You Only Look Once)v8 algorithm.The algorithmintegrates advanced attention mechanisms and a smalltarget detection head to significantly enhance detection performance and efficiency.Firstly,an SE(Squeeze-and-Excitation)mechanism is incorporated into the backbone network to fortify the extraction of resilient features and precise target localization.This mechanism models feature channel dependencies,enabling adaptive adjustment of channel importance,thereby improving recognition of floating litter targets.Secondly,a 160×160 small-target detection layer is designed in the feature fusion neck to mitigate semantic information loss due to varying target scales.This design enhances the fusion of deep and shallow semantic information,improving small target feature representation and enabling better capture and identification of tiny floating litter.Thirdly,to balance performance and efficiency,the GhostConv module replaces part of the conventional convolutions in the feature fusion neck.Additionally,a novel C2fGhost(CSPDarknet53 to 2-Stage Feature Pyramid Networks Ghost)module is introduced to further reduce network parameters.Lastly,to address the challenge of occlusion,a newloss function,WIoU(Wise Intersection over Union)v3 incorporating a flexible and non-monotonic concentration approach,is adopted to improve detection rates for surface floating litter.The outcomes of the experiments demonstrate that the Ghost-YOLO v8 model proposed in this paper performs well in the dataset Marine,significantly enhances precision and recall by 3.3 and 7.6 percentage points,respectively,in contrast with the base model,mAP@0.5 and mAP 0.5:0.95 improve by 5.3 and 4.4 percentage points and reduces the computational volume by 1.88MB,the FPS value hardly decreases,and the efficient real-time identification of floating debris on the water’s surface can be achieved costeffectively. 展开更多
关键词 YOLO v8 surface floating litter target detection attention mechanism small target detection head ghostnet loss function
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融合GhostNet的YOLOv4轻量化网络设计与实现 被引量:1
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作者 石博雅 董学峰 《小型微型计算机系统》 CSCD 北大核心 2024年第3期651-656,共6页
由于存储资源和功耗等限制,在嵌入式设备上部署基于深度学习的目标检测算法存在困难,且效果不佳.基于YOLOv4算法,提出了一种改进的YOLOv4-Light轻量化网络模型,采用GhostNet网络结构替换CSPDarknet53作为主干提取网络,引入CBAM注意力机... 由于存储资源和功耗等限制,在嵌入式设备上部署基于深度学习的目标检测算法存在困难,且效果不佳.基于YOLOv4算法,提出了一种改进的YOLOv4-Light轻量化网络模型,采用GhostNet网络结构替换CSPDarknet53作为主干提取网络,引入CBAM注意力机制关注通道和空间两个维度的特征信息,并利用感知量化方法对权重进行INT8量化处理,在保证精度的情况下降低网络模型规模和参数量.在PC端和NVIDIA Jetson Xavier NX上选用VisDrone无人机数据集分别对网络模型进行测试,结果表明YOLOv4-GhostNet-CBAM模型的尺寸是160M,比YOLOv4降低了34.43%;检测速率最高可达到34.6FPS,比YOLOv4提高了56.6%.YOLO-Light模型的尺寸是40.2M,比YOLOv4降低了83.5%;检测速率最高可达到78.6FPS,为YOLOv4的3.6倍,且交并比为0.5时的平均精度均值(mAP50)与YOLOv4相比仅下降了3%.YOLO-Light模型相较于原模型优势明显,能够在低功耗的嵌入式设备上完成实时目标检测. 展开更多
关键词 目标检测 YOLOv4 轻量化网络 嵌入式设备 INT8量化
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Targeted Deposition in a Lithiophilic Silver-Modified 3D Cu Host for Lithium-Metal Anodes 被引量:2
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作者 Weiyi Chen Shaopeng Li +2 位作者 Chenhui Wang Hui Dou Xiaogang Zhang 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2023年第5期355-363,共9页
Lithium-metal batteries are regarded as the"Holy Grail"of next-generation batteries.However,lithium dendrite and anode volume expansion in cycles seriously hinders lithium-metal battery applications.Herein,w... Lithium-metal batteries are regarded as the"Holy Grail"of next-generation batteries.However,lithium dendrite and anode volume expansion in cycles seriously hinders lithium-metal battery applications.Herein,we propose a precise and efficient strategy for stabilizing lithium-metal batteries via a lithiophilic Ag-modified Cu current host(Li@CuM/Ag).By applying the magnetron sputtering method,the lithiophilic silver layer can be anchored homogeneously on the Cu mesh.The lithiophilic silver layer effectively guides uniform Li deposition in the 3D host and realizes spatial control over Li nucleation.In addition,a dendrite-free lithium anode is successfully realized,which has been proven by in situ optical dynamic tests and Li deposition simulations.The symmetrical cell can maintain a low overpotential(230 mV)and long cycle life(90 h)at a large current of 10 mA cm^(-2)for a plating amount of 3 mAh cm^(-2).Furthermore,Li@CuM/Ag||LiCoO2 cells exhibited a high-capacity retention rate(86.39%)after 150 cycles at 2 C.Lithiophilic hosts based on magnetron sputtering provide a feasible strategy for applications of lithium-metal batteries. 展开更多
关键词 lithiophilic modification lithium-metal battery lithium-metal host magnetron sputtering targeted deposition
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Mitochondrial targeting sequence of magnetoreceptor MagR:More than just targeting 被引量:2
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作者 Yanqi Zhang Peng Zhang +10 位作者 Junjun Wang Jing Zhang Tianyang Tong Xiujuan Zhou Yajie Zhou Mengke Wei Chuanlin Feng Jinqian Li Xin Zhang Can Xie Tiantian Cai 《Zoological Research》 SCIE CSCD 2024年第3期468-477,共10页
Iron-sulfur clusters(ISC)are essential cofactors for proteins involved in various biological processes,such as electron transport,biosynthetic reactions,DNA repair,and gene expression regulation.ISC assembly protein I... Iron-sulfur clusters(ISC)are essential cofactors for proteins involved in various biological processes,such as electron transport,biosynthetic reactions,DNA repair,and gene expression regulation.ISC assembly protein IscA1(or MagR)is found within the mitochondria of most eukaryotes.Magnetoreceptor(MagR)is a highly conserved A-type iron and iron-sulfur cluster-binding protein,characterized by two distinct types of iron-sulfur clusters,[2Fe-2S]and[3Fe-4S],each conferring unique magnetic properties.MagR forms a rod-like polymer structure in complex with photoreceptive cryptochrome(Cry)and serves as a putative magnetoreceptor for retrieving geomagnetic information in animal navigation.Although the N-terminal sequences of MagR vary among species,their specific function remains unknown.In the present study,we found that the N-terminal sequences of pigeon MagR,previously thought to serve as a mitochondrial targeting signal(MTS),were not cleaved following mitochondrial entry but instead modulated the efficiency with which iron-sulfur clusters and irons are bound.Moreover,the N-terminal region of MagR was required for the formation of a stable MagR/Cry complex.Thus,the N-terminal sequences in pigeon MagR fulfil more important functional roles than just mitochondrial targeting.These results further extend our understanding of the function of MagR and provide new insights into the origin of magnetoreception from an evolutionary perspective. 展开更多
关键词 Magnetoreceptor(MagR) N-terminal sequence Mitochondrial targeting signal Iron-sulfur cluster
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Classification and technical target of water electrolysis for hydrogen production 被引量:1
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作者 Kahyun Ham Sooan Bae Jaeyoung Lee 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第8期554-576,I0012,共24页
Continuous efforts are underway to reduce carbon emissions worldwide in response to global climate change.Water electrolysis technology,in conjunction with renewable energy,is considered the most feasible hydrogen pro... Continuous efforts are underway to reduce carbon emissions worldwide in response to global climate change.Water electrolysis technology,in conjunction with renewable energy,is considered the most feasible hydrogen production technology based on the viable possibility of large-scale hydrogen production and the zero-carbon-emission nature of the process.However,for hydrogen produced via water electrolysis systems to be utilized in various fields in practice,the unit cost of hydrogen production must be reduced to$1/kg H_(2).To achieve this unit cost,technical targets for water electrolysis have been suggested regarding components in the system.In this paper,the types of water electrolysis systems and the limitations of water electrolysis system components are explained.We suggest guideline with recent trend for achieving this technical target and insights for the potential utilization of water electrolysis technology. 展开更多
关键词 Water electrolysis Hydrogen production Technical target ELECTROCHEMISTRY
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Stable immobilization of lithium polysulfides using three-dimensional ordered mesoporous Mn_(2)O_(3) as the host material in lithium-sulfur batteries 被引量:1
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作者 Sung Joon Park Yun Jeong Choi +6 位作者 Hyun-seung Kim Min Joo Hong Hongjun Chang Janghyuk Moon Young-Jun Kim Junyoung Mun Ki Jae Kim 《Carbon Energy》 SCIE EI CAS CSCD 2024年第6期99-112,共14页
Lithium-sulfur batteries(LSBs)have drawn significant attention owing to their high theoretical discharge capacity and energy density.However,the dissolution of long-chain polysulfides into the electrolyte during the c... Lithium-sulfur batteries(LSBs)have drawn significant attention owing to their high theoretical discharge capacity and energy density.However,the dissolution of long-chain polysulfides into the electrolyte during the charge and discharge process(“shuttle effect”)results in fast capacity fading and inferior electrochemical performance.In this study,Mn_(2)O_(3)with an ordered mesoporous structure(OM-Mn_(2)O_(3))was designed as a cathode host for LSBs via KIT-6 hard templating,to effectively inhibit the polysulfide shuttle effect.OM-Mn_(2)O_(3)offers numerous pores to confine sulfur and tightly anchor the dissolved polysulfides through the combined effects of strong polar-polar interactions,polysulfides,and sulfur chain catenation.The OM-Mn_(2)O_(3)/S composite electrode delivered a discharge capacity of 561 mAh g^(-1) after 250 cycles at 0.5 C owing to the excellent performance of OM-Mn_(2)O_(3).Furthermore,it retained a discharge capacity of 628mA h g^(-1) even at a rate of 2 C,which was significantly higher than that of a pristine sulfur electrode(206mA h g^(-1)).These findings provide a prospective strategy for designing cathode materials for high-performance LSBs. 展开更多
关键词 host material lithium-sulfur battery ordered mesoporous structure shuttle effect transition-metal oxides
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Targeted regeneration and upcycling of spent graphite by defect‐driven tin nucleation 被引量:1
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作者 Zhiheng Cheng Zhiling Luo +7 位作者 Hao Zhang Wuxing Zhang Wang Gao Yang Zhang Long Qie Yonggang Yao Yunhui Huang Kun Kelvin Fu 《Carbon Energy》 SCIE EI CAS CSCD 2024年第4期91-103,共13页
The recycling of spent batteries has become increasingly important owing to their wide applications,abundant raw material supply,and sustainable development.Compared with the degraded cathode,spent anode graphite ofte... The recycling of spent batteries has become increasingly important owing to their wide applications,abundant raw material supply,and sustainable development.Compared with the degraded cathode,spent anode graphite often has a relatively intact structure with few defects after long cycling.Yet,most spent graphite is simply burned or discarded due to its limited value and inferior performance on using conventional recycling methods that are complex,have low efficiency,and fail in performance restoration.Herein,we propose a fast,efficient,and“intelligent”strategy to regenerate and upcycle spent graphite based on defect‐driven targeted remediation.Using Sn as a nanoscale healant,we used rapid heating(~50 ms)to enable dynamic Sn droplets to automatically nucleate around the surface defects on the graphite upon cooling owing to strong binding to the defects(~5.84 eV/atom),thus simultaneously achieving Sn dispersion and graphite remediation.As a result,the regenerated graphite showed enhanced capacity and cycle stability(458.9 mAh g^(−1) at 0.2 A g^(−1) after 100 cycles),superior to those of commercial graphite.Benefiting from the self‐adaption of Sn dispersion,spent graphite with different degrees of defects can be regenerated to similar structures and performance.EverBatt analysis indicates that targeted regeneration and upcycling have significantly lower energy consumption(~99%reduction)and near‐zero CO_(2) emission,and yield much higher profit than hydrometallurgy,which opens a new avenue for direct upcycling of spend graphite in an efficient,green,and profitable manner for sustainable battery manufacture. 展开更多
关键词 battery recycling spent graphite targeted regeneration upcycling graphite
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Mitophagy in intracerebral hemorrhage:a new target for therapeutic intervention 被引量:2
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作者 Yiyang Chen Wenxuan Tang +5 位作者 Xinqi Huang Yumei An Jiawen Li Shengye Yuan Haiyan Shan Mingyang Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期316-323,共8页
Intracerebral hemorrhage is a life-threatening condition with a high fatality rate and severe sequelae.However,there is currently no treatment available for intracerebral hemorrhage,unlike for other stroke subtypes.Re... Intracerebral hemorrhage is a life-threatening condition with a high fatality rate and severe sequelae.However,there is currently no treatment available for intracerebral hemorrhage,unlike for other stroke subtypes.Recent studies have indicated that mitochondrial dysfunction and mitophagy likely relate to the pathophysiology of intracerebral hemorrhage.Mitophagy,or selective autophagy of mitochondria,is an essential pathway to preserve mitochondrial homeostasis by clearing up damaged mitochondria.Mitophagy markedly contributes to the reduction of secondary brain injury caused by mitochondrial dysfunction after intracerebral hemorrhage.This review provides an overview of the mitochondrial dysfunction that occurs after intracerebral hemorrhage and the underlying mechanisms regarding how mitophagy regulates it,and discusses the new direction of therapeutic strategies targeting mitophagy for intracerebral hemorrhage,aiming to determine the close connection between mitophagy and intracerebral hemorrhage and identify new therapies to modulate mitophagy after intracerebral hemorrhage.In conclusion,although only a small number of drugs modulating mitophagy in intracerebral hemorrhage have been found thus far,most of which are in the preclinical stage and require further investigation,mitophagy is still a very valid and promising therapeutic target for intracerebral hemorrhage in the long run. 展开更多
关键词 intracerebral hemorrhage mitochondrial dysfunction MITOPHAGY NEUROINFLAMMATION NEUROPROTECTION reactive oxygen species secondary brain injury therapeutic target
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High-speed penetration of ogive-nose projectiles into thick concrete targets:Tests and a projectile nose evolution model 被引量:1
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作者 Xu Li Yan Liu +4 位作者 Junbo Yan Zhenqing Shi Hongfu Wang Yingliang Xu Fenglei Huang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期553-571,共19页
The majority of the projectiles used in the hypersonic penetration study are solid flat-nosed cylindrical projectiles with a diameter of less than 20 mm.This study aims to fill the gap in the experimental and analytic... The majority of the projectiles used in the hypersonic penetration study are solid flat-nosed cylindrical projectiles with a diameter of less than 20 mm.This study aims to fill the gap in the experimental and analytical study of the evolution of the nose shape of larger hollow projectiles under hypersonic penetration.In the hypersonic penetration test,eight ogive-nose AerMet100 steel projectiles with a diameter of 40 mm were launched to hit concrete targets with impact velocities that ranged from 1351 to 1877 m/s.Severe erosion of the projectiles was observed during high-speed penetration of heterogeneous targets,and apparent localized mushrooming occurred in the front nose of recovered projectiles.By examining the damage to projectiles,a linear relationship was found between the relative length reduction rate and the initial kinetic energy of projectiles in different penetration tests.Furthermore,microscopic analysis revealed the forming mechanism of the localized mushrooming phenomenon for eroding penetration,i.e.,material spall erosion abrasion mechanism,material flow and redistribution abrasion mechanism and localized radial upsetting deformation mechanism.Finally,a model of highspeed penetration that included erosion was established on the basis of a model of the evolution of the projectile nose that considers radial upsetting;the model was validated by test data from the literature and the present study.Depending upon the impact velocity,v0,the projectile nose may behave as undistorted,radially distorted or hemispherical.Due to the effects of abrasion of the projectile and enhancement of radial upsetting on the duration and amplitude of the secondary rising segment in the pulse shape of projectile deceleration,the predicted DOP had an upper limit. 展开更多
关键词 High-speed penetration Concrete target EROSION Projectile nose evolution model
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Precision targeting in hepatocellular carcinoma:Exploring ligandreceptor mediated nanotherapy 被引量:1
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作者 Xia-Qing Zhou Ya-Ping Li Shuang-Suo Dang 《World Journal of Hepatology》 2024年第2期164-176,共13页
Hepatocellular carcinoma(HCC)is the most common primary liver cancer and poses a major challenge to global health due to its high morbidity and mortality.Conventional chemotherapy is usually targeted to patients with ... Hepatocellular carcinoma(HCC)is the most common primary liver cancer and poses a major challenge to global health due to its high morbidity and mortality.Conventional chemotherapy is usually targeted to patients with intermediate to advanced stages,but it is often ineffective and suffers from problems such as multidrug resistance,rapid drug clearance,nonspecific targeting,high side effects,and low drug accumulation in tumor cells.In response to these limitations,recent advances in nanoparticle-mediated targeted drug delivery technologies have emerged as breakthrough approaches for the treatment of HCC.This review focuses on recent advances in nanoparticle-based targeted drug delivery systems,with special attention to various receptors overexpressed on HCC cells.These receptors are key to enhancing the specificity and efficacy of nanoparticle delivery and represent a new paradigm for actively targeting and combating HCC.We comprehensively summarize the current understanding of these receptors,their role in nanoparticle targeting,and the impact of such targeted therapies on HCC.By gaining a deeper understanding of the receptor-mediated mechanisms of these innovative therapies,more effective and precise treatment of HCC can be achieved. 展开更多
关键词 targetING Hepatocellular carcinoma RECEPTOR NANOMEDICINE CHEMOTHERAPY
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基于TARGET融合ARCS动机模型的应用统计学课程教学改革研究 被引量:1
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作者 王凤姣 王留芳 《高教学刊》 2024年第22期148-151,共4页
学生的学习动机直接关系到课程教学目标的达成,激发学习动机是推动课程教学改革的应有之义。将TARGET和ARCS学习动机模型引入应用统计学课程教学,分析当前教学中存在的动机问题,提出有效激发学生动机的教学方案和实践策略,结果既可促进... 学生的学习动机直接关系到课程教学目标的达成,激发学习动机是推动课程教学改革的应有之义。将TARGET和ARCS学习动机模型引入应用统计学课程教学,分析当前教学中存在的动机问题,提出有效激发学生动机的教学方案和实践策略,结果既可促进应用统计学课程教学质量提升,也可为其他相似课程教学设计提供参考借鉴。 展开更多
关键词 target模型 ARCS学习动机模型 应用统计学 课程教学 教学改革
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Real-time Rescue Target Detection Based on UAV Imagery for Flood Emergency Response 被引量:1
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作者 ZHAO Bofei SUI Haigang +2 位作者 ZHU Yihao LIU Chang WANG Wentao 《Journal of Geodesy and Geoinformation Science》 CSCD 2024年第1期74-89,共16页
Timely acquisition of rescue target information is critical for emergency response after a flood disaster.Unmanned Aerial Vehicles(UAVs)equipped with remote sensing capabilities offer distinct advantages,including hig... Timely acquisition of rescue target information is critical for emergency response after a flood disaster.Unmanned Aerial Vehicles(UAVs)equipped with remote sensing capabilities offer distinct advantages,including high-resolution imagery and exceptional mobility,making them well suited for monitoring flood extent and identifying rescue targets during floods.However,there are some challenges in interpreting rescue information in real time from flood images captured by UAVs,such as the complexity of the scenarios of UAV images,the lack of flood rescue target detection datasets and the limited real-time processing capabilities of the airborne on-board platform.Thus,we propose a real-time rescue target detection method for UAVs that is capable of efficiently delineating flood extent and identifying rescue targets(i.e.,pedestrians and vehicles trapped by floods).The proposed method achieves real-time rescue information extraction for UAV platforms by lightweight processing and fusion of flood extent extraction model and target detection model.The flood inundation range is extracted by the proposed method in real time and detects targets such as people and vehicles to be rescued based on this layer.Our experimental results demonstrate that the Intersection over Union(IoU)for flood water extraction reaches an impressive 80%,and the IoU for real-time flood water extraction stands at a commendable 76.4%.The information on flood stricken targets extracted by this method in real time can be used for flood emergency rescue. 展开更多
关键词 UAV flood extraction target rescue detection real time
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Deployment optimization for target perpetual coverage in energy harvesting wireless sensor network 被引量:1
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作者 Zhenkun Jin Yixuan Geng +4 位作者 Chenlu Zhu Yunzhi Xia Xianjun Deng Lingzhi Yi Xianlan Wang 《Digital Communications and Networks》 SCIE CSCD 2024年第2期498-508,共11页
Energy limitation of traditional Wireless Sensor Networks(WSNs)greatly confines the network lifetime due to generating and processing massive sensing data with a limited battery.The energy harvesting WSN is a novel ne... Energy limitation of traditional Wireless Sensor Networks(WSNs)greatly confines the network lifetime due to generating and processing massive sensing data with a limited battery.The energy harvesting WSN is a novel network architecture to address the limitation of traditional WSN.However,existing coverage and deployment schemes neglect the environmental correlation of sensor nodes and external energy with respect to physical space.Comprehensively considering the spatial correlation of the environment and the uneven distribution of energy in energy harvesting WSN,we investigate how to deploy a collection of sensor nodes to save the deployment cost while ensuring the target perpetual coverage.The Confident Information Coverage(CIC)model is adopted to formulate the CIC Minimum Deployment Cost Target Perpetual Coverage(CICMTP)problem to minimize the deployed sensor nodes.As the CICMTP is NP-hard,we devise two approximation algorithms named Local Greedy Threshold Algorithm based on CIC(LGTA-CIC)and Overall Greedy Search Algorithm based on CIC(OGSA-CIC).The LGTA-CIC has a low time complexity and the OGSA-CIC has a better approximation rate.Extensive simulation results demonstrate that the OGSA-CIC is able to achieve lower deployment cost and the performance of the proposed algorithms outperforms GRNP,TPNP and EENP algorithms. 展开更多
关键词 Energy harvesting WSN Deployment optimization Confident information coverage(CIC) target perpetual coverage
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Humanβ-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long noncoding RNA TCONS_00014506 被引量:1
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作者 Yu-Xin Zhao Yan Cui +9 位作者 Xin-Hong Li Wen-Hong Yang Shi-Xiang An Jia-Xian Cui Min-Yu Zhang Jing-Kun Lu Xuan Zhang Xiu-Mei Wang Li-Li Bao Peng-Wei Zhao 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第4期1465-1478,共14页
BACKGROUND Colorectal cancer has a low 5-year survival rate and high mortality.Humanβ-defensin-1(hBD-1)may play an integral function in the innate immune system,contributing to the recognition and destruction of canc... BACKGROUND Colorectal cancer has a low 5-year survival rate and high mortality.Humanβ-defensin-1(hBD-1)may play an integral function in the innate immune system,contributing to the recognition and destruction of cancer cells.Long non-coding RNAs(lncRNAs)are involved in the process of cell differentiation and growth.AIM To investigate the effect of hBD-1 on the mammalian target of rapamycin(mTOR)pathway and autophagy in human colon cancer SW620 cells.METHODS CCK8 assay was utilized for the detection of cell proliferation and determination of the optimal drug concentration.Colony formation assay was employed to assess the effect of hBD-1 on SW620 cell proliferation.Bioinformatics was used to screen potentially biologically significant lncRNAs related to the mTOR pathway.Additionally,p-mTOR(Ser2448),Beclin1,and LC3II/I expression levels in SW620 cells were assessed through Western blot analysis.RESULTS hBD-1 inhibited the proliferative ability of SW620 cells,as evidenced by the reduction in the colony formation capacity of SW620 cells upon exposure to hBD-1.hBD-1 decreased the expression of p-mTOR(Ser2448)protein and increased the expression of Beclin1 and LC3II/I protein.Furthermore,bioinformatics analysis identified seven lncRNAs(2 upregulated and 5 downregulated)related to the mTOR pathway.The lncRNA TCONS_00014506 was ultimately selected.Following the inhibition of the lncRNA TCONS_00014506,exposure to hBD-1 inhibited p-mTOR(Ser2448)and promoted Beclin1 and LC3II/I protein expression.CONCLUSION hBD-1 inhibits the mTOR pathway and promotes autophagy by upregulating the expression of the lncRNA TCONS_00014506 in SW620 cells. 展开更多
关键词 Colon cancer Humanβ-defensin-1 LncRNA Mammalian target of rapamycin AUTOPHAGY
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Natural gas exploration potential and favorable targets of Permian Fengcheng Formation in the western Central Depression of Junggar Basin,NW China 被引量:1
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作者 TANG Yong HU Suyun +4 位作者 GONG Deyu YOU Xincai LI Hui LIU Hailei CHEN Xuan 《Petroleum Exploration and Development》 SCIE 2024年第3期563-575,共13页
Based on the organic geochemical data and the molecular and stable carbon isotopic compositions of natural gas of the Lower Permian Fengcheng Formation in the western Central Depression of Junggar Basin,combined with ... Based on the organic geochemical data and the molecular and stable carbon isotopic compositions of natural gas of the Lower Permian Fengcheng Formation in the western Central Depression of Junggar Basin,combined with sedimentary environment analysis and hydrocarbon-generating simulation,the gas-generating potential of the Fengcheng source rock is evaluated,the distribution of large-scale effective source kitchen is described,the genetic types of natural gas are clarified,and four types of favorable exploration targets are selected.The results show that:(1)The Fengcheng Formation is a set of oil-prone source rocks,and the retained liquid hydrocarbon is conducive to late cracking into gas,with characteristics of high gas-generating potential and late accumulation;(2)The maximum thickness of Fengcheng source rock reaches 900 m.The source rock has entered the main gas-generating stage in Penyijingxi and Shawan sags,and the area with gas-generating intensity greater than 20×10^(8) m^(3)/km^(2) is approximately 6500 km^(2).(3)Around the western Central Depression,highly mature oil-type gas with light carbon isotope composition was identified to be derived from the Fengcheng source rocks mainly,while the rest was coal-derived gas from the Carboniferous source rock;(4)Four types of favorable exploration targets with exploration potential were developed in the western Central Depression which are structural traps neighboring to the source,stratigraphic traps neighboring to the source,shale-gas type within the source,and structural traps within the source.Great attention should be paid to these targets. 展开更多
关键词 Junggar Basin western Central Depression Lower Permian Fengcheng Formation gas-generating potential gas-source correlation exploration target
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基于Ghost-TiFPN的轻量化快速目标跟踪算法
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作者 阴国华 齐咏生 +2 位作者 刘利强 苏建强 张丽杰 《兵工学报》 EI CAS CSCD 北大核心 2024年第5期1703-1716,共14页
针对传统孪生目标跟踪算法体量大、难以在嵌入式设备部署以及其在目标尺度变化大、有相似物干扰等条件下效果不佳的问题,提出一种新的轻量化快速跟踪(Ghost fast Tracking with TiFPN and Retriever,GTtracker)算法。引入Ghost机制,对Re... 针对传统孪生目标跟踪算法体量大、难以在嵌入式设备部署以及其在目标尺度变化大、有相似物干扰等条件下效果不佳的问题,提出一种新的轻量化快速跟踪(Ghost fast Tracking with TiFPN and Retriever,GTtracker)算法。引入Ghost机制,对Resnet网络进行重新设计,构建一种轻量化G-Resnet网络对跟踪目标进行快速特征提取。设计轻量自适应加权融合(Tiny adaptive weighted fusion algorithm Feature Pyramid Network,TiFPN)算法,进一步加强特征信息的融合,解决相似物干扰问题。设计一种轻量化区域回归网络(Ghost Decoupled Net,GDnet),以实现目标分类、交并比(Intersection-over-Union,IoU)计算以及边界框回归,并在跟踪阶段应用一种新的目标寻回器提升算法跟踪的成功率。在OTB100数据集和VOT2020数据集上进行算法验证,并移植算法到嵌入式设备Jetson Xavier NX上进行性能测试。实验结果均表明算法的有效性和优越性,相比经典孪生目标跟踪(SiamCAR)算法,新方法在精度和期望平均重叠率(Expected Average Overlap,EAO)指标均相似的前提下,能够实现更快的运行速度,可在Jetson Xavier NX上实时运行,达到30帧/s,且能有效解决相似物干扰、尺度变化大等问题。 展开更多
关键词 目标跟踪 孪生网络 轻量化 嵌入式设备
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Target acquisition performance in the presence of JPEG image compression
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作者 Boban Bondzulic Nenad Stojanovic +3 位作者 Vladimir Lukin Sergey A.Stankevich Dimitrije Bujakovic Sergii Kryvenko 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期30-41,共12页
This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image... This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image.Four new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction results.It is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is used.In future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition performance.Similarity values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%. 展开更多
关键词 JPEG compression target acquisition performance Image quality assessment Just noticeable difference Probability of target detection target mean searching time
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Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment
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作者 Mengxin Wang Stephen Vulcano +7 位作者 Changlu Xu Renjian Xie Weijie Peng Jie Wang Qiaojun Liu Lee Jia Zhi Li Yumei Li 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第3期308-320,共13页
Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced functionality.Mutation or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenes... Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced functionality.Mutation or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ribosomopathies in clinic,collectively known as ribosomopathy genes.Emerging data suggest that ribosomopathy patients exhibit a significantly heightened susceptibility to cancer.Abnormal ribosome biogenesis and dysregulation of some ribosomopathy genes have also been found to be intimately associated with cancer development.The correlation between ribosome biogenesis or ribosomopathy and the development of malignancies has been well established.This work aims to review the recent advances in the research of ribosomopathy genes among human cancers and meanwhile,to excavate the potential role of these genes,which have not or rarely been reported in cancer,in the disease development across cancers.We plan to establish a theoretical framework between the ribosomopathy gene and cancer development,to further facilitate the potential of these genes as diagnostic biomarker as well as pharmaceutical targets for cancer treatment. 展开更多
关键词 Ribosome biogenesis Ribosomopathy gene Cancer treatment target Pharmaceutical target
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An equivalent target plate damage probability calculation mathematics model and damage evaluation method
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作者 Hanshan Li Xiaoqian Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第11期82-103,共22页
Aiming at the requirement of damage testing and evaluation of equivalent target plate based on the explosion of intelligent ammunition, this paper proposes a novel method for damage testing and evaluation method of ci... Aiming at the requirement of damage testing and evaluation of equivalent target plate based on the explosion of intelligent ammunition, this paper proposes a novel method for damage testing and evaluation method of circumferential equivalent target plate. Leveraging the dispersion characteristics parameters of fragment, we establish a calculation model of the fragment power situation and the damage calculation model under the condition of fragment ultimate penetration equivalent target plate. The damage model of equivalent target plate involves the fragment dispersion density, the local perforation damage criterion, the tearing damage model, and the damage probability. We use the camera to obtain the image of the equivalent target plate with fragment perforation, and research the algorithm of fragment distribution position recognition and fragment perforation area calculation method on the equivalent target plate by image processing technology. Based on the obtained parameters of the breakdown position and perforation area of fragments on equivalent target plate, we apply to damage calculation model of equivalent target plate, and calculate the damage probability of each equivalent target plate, and use the combined probabilistic damage calculation method to obtain the damage evaluation results of the circumferential equivalent target plate in an intelligent ammunition explosion experiment. Through an experimental testing, we verify the feasibility and rationality of the proposed damage evaluation method by comparison, the calculation results can reflect the actual damage effect of the equivalent target plate. 展开更多
关键词 target damage evaluation Damage probability FRAGMENTS Equivalent target plate Image processing
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Target Detection Algorithm in Foggy Scenes Based on Dual Subnets
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作者 Yuecheng Yu Liming Cai +3 位作者 Anqi Ning Jinlong Shi Xudong Chen Shixin Huang 《Computers, Materials & Continua》 SCIE EI 2024年第2期1915-1931,共17页
Under the influence of air humidity,dust,aerosols,etc.,in real scenes,haze presents an uneven state.In this way,the image quality and contrast will decrease.In this case,It is difficult to detect the target in the ima... Under the influence of air humidity,dust,aerosols,etc.,in real scenes,haze presents an uneven state.In this way,the image quality and contrast will decrease.In this case,It is difficult to detect the target in the image by the universal detection network.Thus,a dual subnet based on multi-task collaborative training(DSMCT)is proposed in this paper.Firstly,in the training phase,the Gated Context Aggregation Network(GCANet)is used as the supervisory network of YOLOX to promote the extraction of clean information in foggy scenes.In the test phase,only the YOLOX branch needs to be activated to ensure the detection speed of the model.Secondly,the deformable convolution module is used to improve GCANet to enhance the model’s ability to capture details of non-homogeneous fog.Finally,the Coordinate Attention mechanism is introduced into the Vision Transformer and the backbone network of YOLOX is redesigned.In this way,the feature extraction ability of the network for deep-level information can be enhanced.The experimental results on artificial fog data set FOG_VOC and real fog data set RTTS show that the map value of DSMCT reached 86.56%and 62.39%,respectively,which was 2.27%and 4.41%higher than the current most advanced detection model.The DSMCT network has high practicality and effectiveness for target detection in real foggy scenes. 展开更多
关键词 target detection fog target detection YOLOX twin network multi-task learning
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