The aim is to reconstruct a complete and detailed clothed human from a single-view input.Implicit function is suitable for this task because it represents fine shape details and varied topology.Current methods,however...The aim is to reconstruct a complete and detailed clothed human from a single-view input.Implicit function is suitable for this task because it represents fine shape details and varied topology.Current methods,however,often suffer from artefacts such as broken or disembodied body parts,missing details,or depth ambiguity due to the ambiguity and complexity of human articulation.The main issue observed by the authors is structureagnostic.To address these problems,the authors fully utilise the skinned multi-person linear(SMPL)model and propose a method using the Skeleton-aware Implicit Function(SIF).To alleviate the broken or disembodied body parts,the proposed skeleton-aware structure prior makes the skeleton awareness into an implicit function,which consists of a bone-guided sampling strategy and a skeleton-relative encoding strategy.To deal with the missing details and depth ambiguity problems,the authors’body-guided pixel-aligned feature exploits the SMPL to enhance 2D normal and depth semantic features,and the proposed feature aggregation uses the extra geometry-aware prior to enabling a more plausible merging with less noisy geometry.Additionally,SIF is also adapted to the RGB-D input,and experimental results show that SIF outperforms the state-of-the-arts methods on challenging datasets from Twindom and Thuman3.0.展开更多
Reconstructing 3D digital models of humans from sensory data is a long-standing problem in computer vision and graphics with a variety of applications in VR/AR,film production,and human–computer interaction,etc.While...Reconstructing 3D digital models of humans from sensory data is a long-standing problem in computer vision and graphics with a variety of applications in VR/AR,film production,and human–computer interaction,etc.While a huge amount of effort has been devoted to developing various capture hardware and reconstruction algorithms,traditional reconstruction pipelines may still suffer from high-cost capture systems and tedious capture processes,which prevent them from being easily accessible.Moreover,the dedicatedly hand-crafted pipelines are prone to reconstruction artifacts,resulting in limited visual quality.To solve these challenges,the recent trend in this area is to use deep neural networks to improve reconstruction efficiency and robustness by learning human priors from existing data.Neural network-based implicit functions have been also shown to be a favorable 3D representation compared to traditional forms like meshes and voxels.Furthermore,neural rendering has emerged as a powerful tool to achieve highly photorealistic modeling and re-rendering of humans by end-to-end optimizing the visual quality of output images.In this article,we will briefly review these advances in this fast-developing field,discuss the advantages and limitations of different approaches,and finally,share some thoughts on future research directions.展开更多
Cosmetic safety evaluation employs a series of toxicological tests, on both qualitative and quantitative levels, to assess the potential risks for the daily use of selected cosmetic ingredients and final products. Tra...Cosmetic safety evaluation employs a series of toxicological tests, on both qualitative and quantitative levels, to assess the potential risks for the daily use of selected cosmetic ingredients and final products. Traditionally, safety evaluation of cosmetics uses animal tests. With the development of in vitro science and the 3R (Reduction, Replacement and Refinement) principle, three-dimensional reconstructed human epidermis (3D-RHE) models have been developed and widely applied in cosmetic safety evaluation. Reconstructed human skin models possess anatomy and metabolism biology similar to real human tissue. This paper reviews the current application of 3D-RHE models in the safety evaluation of skin irritation, eye irritation, phototoxicity and genotoxicity potential of cosmetic ingredients/formulas. The advantages and disadvantages of using skin models are also discussed, and comments and suggestions are given for its future development.展开更多
Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Da...Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Data mining of omics datasets has enabled the generation of new hypotheses based on differentially regulated biological molecules associated with disease mechanisms,which can be tested experimentally for improved diagnostic and therapeutic targeting of neurodegenerative diseases.Importantly,integrating multi-omics data using a systems bioinformatics approach will advance the understanding of the layered and interactive network of biological regulation that exchanges systemic knowledge to facilitate the development of a comprehensive human brain profile.In this review,we first summarize data mining studies utilizing datasets from the individual type of omics analysis,including epigenetics/epigenomics,transcriptomics,proteomics,metabolomics,lipidomics,and spatial omics,pertaining to Alzheimer's disease,Parkinson's disease,and multiple sclerosis.We then discuss multi-omics integration approaches,including independent biological integration and unsupervised integration methods,for more intuitive and informative interpretation of the biological data obtained across different omics layers.We further assess studies that integrate multi-omics in data mining which provide convoluted biological insights and offer proof-of-concept proposition towards systems bioinformatics in the reconstruction of brain networks.Finally,we recommend a combination of high dimensional bioinformatics analysis with experimental validation to achieve translational neuroscience applications including biomarker discovery,therapeutic development,and elucidation of disease mechanisms.We conclude by providing future perspectives and opportunities in applying integrative multi-omics and systems bioinformatics to achieve precision phenotyping of neurodegenerative diseases and towards personalized medicine.展开更多
Human expression rapid reconstruction has many potential applications in entertainment and social security. In this work, a rapid human expression measurement system based on a digital fringe projection and phase-shif...Human expression rapid reconstruction has many potential applications in entertainment and social security. In this work, a rapid human expression measurement system based on a digital fringe projection and phase-shift technique is developed. The measurement system consists of a digital light processing (DLP) projector and a high-speed change-coupled device (CCD) camera. The DLP projector is used to project computer-generated fringe patterns onto the human face, and the high-speed CCD camera synchronized with the projector acquires the fringe images at a frame rate of 30 frames/s. Based on a three-step phase-shifting method and an accurate phase-height mapping algorithm, each frame of the 3-D human expression can be reconstructed. The principle of the proposed method is described and some experimental results are presented to demonstrate its performance. The experiment results show that the measurement system can reconstruct accurate 3-D human expression. An obvious merit of this method is that it can reconstruct the 3-D human expression in a very short time and it is not sensitive to the movement of the face during the measurement processing.展开更多
With the rapid development of computing technology, three-dimensional (3D) human body models and their dynamic motions are widely used in the digital entertainment industry. Human performance mainly involves human b...With the rapid development of computing technology, three-dimensional (3D) human body models and their dynamic motions are widely used in the digital entertainment industry. Human performance mainly involves human body shapes and motions. Key research problems in human performance animation include how to capture and analyze static geometric appearance and dynamic movement of human bodies, and how to simulate human body motions with physical effects. In this survey, according to the main research directions of human body performance capture and animation, we summarize recent advances in key research topics, namely human body surface reconstruction, motion capture and synthesis, as well as physics-based motion simulation, and further discuss future research problems and directions. We hope this will be helpful for readers to have a comprehensive understanding of human performance capture and animation.展开更多
基金National Key R&D Program of China,Grant/Award Number:2022YFF0901902。
文摘The aim is to reconstruct a complete and detailed clothed human from a single-view input.Implicit function is suitable for this task because it represents fine shape details and varied topology.Current methods,however,often suffer from artefacts such as broken or disembodied body parts,missing details,or depth ambiguity due to the ambiguity and complexity of human articulation.The main issue observed by the authors is structureagnostic.To address these problems,the authors fully utilise the skinned multi-person linear(SMPL)model and propose a method using the Skeleton-aware Implicit Function(SIF).To alleviate the broken or disembodied body parts,the proposed skeleton-aware structure prior makes the skeleton awareness into an implicit function,which consists of a bone-guided sampling strategy and a skeleton-relative encoding strategy.To deal with the missing details and depth ambiguity problems,the authors’body-guided pixel-aligned feature exploits the SMPL to enhance 2D normal and depth semantic features,and the proposed feature aggregation uses the extra geometry-aware prior to enabling a more plausible merging with less noisy geometry.Additionally,SIF is also adapted to the RGB-D input,and experimental results show that SIF outperforms the state-of-the-arts methods on challenging datasets from Twindom and Thuman3.0.
基金The authors would like to acknowledge the support from NSFC(No.62172364).
文摘Reconstructing 3D digital models of humans from sensory data is a long-standing problem in computer vision and graphics with a variety of applications in VR/AR,film production,and human–computer interaction,etc.While a huge amount of effort has been devoted to developing various capture hardware and reconstruction algorithms,traditional reconstruction pipelines may still suffer from high-cost capture systems and tedious capture processes,which prevent them from being easily accessible.Moreover,the dedicatedly hand-crafted pipelines are prone to reconstruction artifacts,resulting in limited visual quality.To solve these challenges,the recent trend in this area is to use deep neural networks to improve reconstruction efficiency and robustness by learning human priors from existing data.Neural network-based implicit functions have been also shown to be a favorable 3D representation compared to traditional forms like meshes and voxels.Furthermore,neural rendering has emerged as a powerful tool to achieve highly photorealistic modeling and re-rendering of humans by end-to-end optimizing the visual quality of output images.In this article,we will briefly review these advances in this fast-developing field,discuss the advantages and limitations of different approaches,and finally,share some thoughts on future research directions.
文摘Cosmetic safety evaluation employs a series of toxicological tests, on both qualitative and quantitative levels, to assess the potential risks for the daily use of selected cosmetic ingredients and final products. Traditionally, safety evaluation of cosmetics uses animal tests. With the development of in vitro science and the 3R (Reduction, Replacement and Refinement) principle, three-dimensional reconstructed human epidermis (3D-RHE) models have been developed and widely applied in cosmetic safety evaluation. Reconstructed human skin models possess anatomy and metabolism biology similar to real human tissue. This paper reviews the current application of 3D-RHE models in the safety evaluation of skin irritation, eye irritation, phototoxicity and genotoxicity potential of cosmetic ingredients/formulas. The advantages and disadvantages of using skin models are also discussed, and comments and suggestions are given for its future development.
基金supported by a Lee Kong Chian School of Medicine Dean’s Postdoctoral Fellowship(021207-00001)from Nanyang Technological University(NTU)Singapore and a Mistletoe Research Fellowship(022522-00001)from the Momental Foundation USA.Jialiu Zeng is supported by a Presidential Postdoctoral Fellowship(021229-00001)from NTU Singapore and an Open Fund Young Investigator Research Grant(OF-YIRG)(MOH-001147)from the National Medical Research Council(NMRC)SingaporeSu Bin Lim is supported by the National Research Foundation(NRF)of Korea(Grant Nos.:2020R1A6A1A03043539,2020M3A9D8037604,2022R1C1C1004756)a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(Grant No.:HR22C1734).
文摘Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Data mining of omics datasets has enabled the generation of new hypotheses based on differentially regulated biological molecules associated with disease mechanisms,which can be tested experimentally for improved diagnostic and therapeutic targeting of neurodegenerative diseases.Importantly,integrating multi-omics data using a systems bioinformatics approach will advance the understanding of the layered and interactive network of biological regulation that exchanges systemic knowledge to facilitate the development of a comprehensive human brain profile.In this review,we first summarize data mining studies utilizing datasets from the individual type of omics analysis,including epigenetics/epigenomics,transcriptomics,proteomics,metabolomics,lipidomics,and spatial omics,pertaining to Alzheimer's disease,Parkinson's disease,and multiple sclerosis.We then discuss multi-omics integration approaches,including independent biological integration and unsupervised integration methods,for more intuitive and informative interpretation of the biological data obtained across different omics layers.We further assess studies that integrate multi-omics in data mining which provide convoluted biological insights and offer proof-of-concept proposition towards systems bioinformatics in the reconstruction of brain networks.Finally,we recommend a combination of high dimensional bioinformatics analysis with experimental validation to achieve translational neuroscience applications including biomarker discovery,therapeutic development,and elucidation of disease mechanisms.We conclude by providing future perspectives and opportunities in applying integrative multi-omics and systems bioinformatics to achieve precision phenotyping of neurodegenerative diseases and towards personalized medicine.
基金Supported by the Eleventh Five-Year Pre-Research Project of China
文摘Human expression rapid reconstruction has many potential applications in entertainment and social security. In this work, a rapid human expression measurement system based on a digital fringe projection and phase-shift technique is developed. The measurement system consists of a digital light processing (DLP) projector and a high-speed change-coupled device (CCD) camera. The DLP projector is used to project computer-generated fringe patterns onto the human face, and the high-speed CCD camera synchronized with the projector acquires the fringe images at a frame rate of 30 frames/s. Based on a three-step phase-shifting method and an accurate phase-height mapping algorithm, each frame of the 3-D human expression can be reconstructed. The principle of the proposed method is described and some experimental results are presented to demonstrate its performance. The experiment results show that the measurement system can reconstruct accurate 3-D human expression. An obvious merit of this method is that it can reconstruct the 3-D human expression in a very short time and it is not sensitive to the movement of the face during the measurement processing.
基金This work was supported by the Knowledge Innovation Program of the Institute of Computing Technology of the Chinese Academy of Sciences under Grant No. ICT20166040, the Science and Technology Service Network Initiative of Chinese Academy of Sciences under Grant No. KFJ-STS-ZDTP-017, the National Natural Science Foundation of China under Grant Nos. 61502453 and 61611130215, the Royal Society-Newton Mobility Grant of UK under Grant No. IE150731, and the CCP (China Computer Federation)-Tencent Open Research Fund of China under Grant No. AGR20160118.
文摘With the rapid development of computing technology, three-dimensional (3D) human body models and their dynamic motions are widely used in the digital entertainment industry. Human performance mainly involves human body shapes and motions. Key research problems in human performance animation include how to capture and analyze static geometric appearance and dynamic movement of human bodies, and how to simulate human body motions with physical effects. In this survey, according to the main research directions of human body performance capture and animation, we summarize recent advances in key research topics, namely human body surface reconstruction, motion capture and synthesis, as well as physics-based motion simulation, and further discuss future research problems and directions. We hope this will be helpful for readers to have a comprehensive understanding of human performance capture and animation.