Experimental study of the effects of a multistage pore-throat structure on the seepage characteristics of sandstones in the Beibuwan Basin:Insights into the flooding mode

To investigate the relationship between grain sizes, seepage capacity, and oil-displacement efficiency in the Liushagang Formation of the Beibuwan Basin, this study identifies the multistage pore-throat structure as a crucial factor through a comparison of oil displacement in microscopic pore-throat experiments. The two-phase flow evaluation method based on the Li-Horne model is utilized to effectively characterize and quantify the seepage characteristics of different reservoirs, closely relating them to the distribution of microscopic pores and throats. It is observed that conglomerate sandstones at different stages exhibit significant heterogeneity and noticeable differences in seepage capacity, highlighting the crucial role played by certain large pore throats in determining seepage capacity and oil displacement efficiency. Furthermore, it was found that the displacement effects of conglomeratic sandstones with strong heterogeneity were inferior to those of conventional homogeneous sandstone, as evidenced by multiple displacement experiments conducted on core samples with varying granularities and flooding systems. Subsequently, core-based experiments on associated gas flooding after water flooding were conducted to address the challenge of achieving satisfactory results in a single displacement mode for reservoirs with significant heterogeneity. The results indicate that the oil recovery rates for associated gas flooding after water flooding increased by 7.3%-16.4% compared with water flooding alone at a gas-oil ratio of approximately 7000 m^(3)/m^(3). Therefore, considering the advantages of gas flooding in terms of seepage capacity, oil exchange ratio, and the potential for two-phase production, gas flooding is recommended as an energy supplement mode for homogeneous reservoirs in the presence of sufficient gas source and appropriate tectonic angle. On the other hand, associated gas flooding after water flooding is suggested to achieve a more favorable development effect compared to a single mode of energy supplementation for strongly heterogeneous sandstone reservoirs.

Adaptive image enhancement algorithm based on fuzzy entropy and human visual characteristics

To overcome the shortcomings of the Lee image enhancement algorithm and its improvement based on the logarithmic image processing(LIP) model, this paper proposes what we believe to be an effective image enhancement algorithm. This algorithm introduces fuzzy entropy, makes full use of neighborhood information, fuzzy information and human visual characteristics.To enhance an image, this paper first carries out the reasonable fuzzy-3 partition of its histogram into the dark region, intermediate region and bright region. It then extracts the statistical characteristics of the three regions and adaptively selects the parameter αaccording to the statistical characteristics of the image’s gray-scale values. It also adds a useful nonlinear transform, thus increasing the ubiquity of the algorithm. Finally, the causes for the gray-scale value overcorrection that occurs in the traditional image enhancement algorithms are analyzed and their solutions are proposed.The simulation results show that our image enhancement algorithm can effectively suppress the noise of an image, enhance its contrast and visual effect, sharpen its edge and adjust its dynamic range.

Intersection capacity based on driver's visual characteristics

In order to reflect the influence of the drivers＇ characteristic differences on intersection capacity under a mixed traffic flow, a driver correction coefficient for the intersection capacity calculation according to the driver＇s visual characteristics is proposed. First, the parameters of the driver＇s visual characteristics at some real roads, including gaze fixation distribution, mean fixation duration, visual angle distribution and some other parameters at intersections, are collected. Then, the relationship between the traffic flow rate at intersections and the parameters of driver eye movements are established. The analytical results indicate that when the traffic flow is unsaturated, the parameters of driver eye movements change relatively little; however, when the traffic flow is saturated, the parameters of driver eye movements change drastically. Finally, the saturation-flow-rate model is modified according to the parameters of driver eye movements; thus, a capacity model of intersections considering the driver＇s visual characteristics is obtained.

Correlation of human epidermal growth factor receptor 2 expression with clinicopathological characteristics and prognosis in gastric cancer

AIM:To investigate human epidermal growth factor receptor 2(HER2) gene amplification and protein expression in Chinese patients with resectable gastric cancer and the association with clinicopathological characteristics and survival.METHODS:One hundred and ninety-seven gastric cancer patients who underwent curative surgery procedures were enrolled into this study.HER2 gene amplification and protein expression were examined using fluorescence in-situ hybridization(FISH) and immunohistochemistry(IHC) analysis on formalin-fixed paraffinembedded gastric cancer samples from all patients.For scoring,Hofmann's HER2 gastric cancer scoring system was adopted.All cases showing IHC3+ or FISH positiv-ity were defined as HER2 positive.Patient clinicopathological data and survival information were collected.Finally,χ 2 statistical analysis was performed to analyze the HER2 positivity rate amongst the subgroups with different clinicopathological characteristics including;gender,age,tumor location,Lauren classification,differentiation,TNM staging,depth of invasion,lymph node metastases and distant metastasis.The probability of survival for different subgroups with different clinicopathological characteristics was calculated using the Kaplan-Meier method and survival curves plotted using log rank inspection.RESULTS:According to Hofmann's HER2 gastric cancer scoring criteria,31 cases(15.74%) were identified as HER2 gene amplified and 19 cases(9.64%) were scored as strongly positive for HER2 membrane staining(3+),25 cases(12.69%) were moderately positive(2+) and 153 cases(77.66%) were HER2 negative(0/1+).The concordance rate between IHC and FISH analyses was 88.83%(175/197).Thirty-six cases were defined as positive for HER2 gene amplification and/or protein expression,with 24 of these cases being eligible for Herceptin treatment according to United States recommendations,and 29 of these cases eligible according to EU recommendations.Highly consistent results were detected between IHC3+,IHC0/1 and FISH(73.68% and 95.42%),but low consistency was observed between IHC2+ and FISH(40.00%).The positivity rates in intestinal type and well-differentiated gastric cancer were higher than those in diffuse/mixed type and poorly-differentiated gastric cancer respectively(28.57% vs 13.43%,P = 0.0103;37.25% vs 11.64%,P < 0.0001),but were not correlated with gender,age,tumor location or TNM stage,depth of invasion,lymph node metastases and distant metastasis.In poorly-differentiated gastric cancer patients,those without lymph node metastasis showed a higher HER2 positivity rate than those with lymph node metastasis(26.47% vs 7.14%,P = 0.0021).This association was not present in thosepatients with well-differentiated gastric cancer(28.57% vs 43.33%,P = 0.2832).Within our patient cohort,26 cases were lost to follow-up.The median survival time for the remaining 171 patients was 18 mo.The median survival times of the HER2 positive and negative groups were 17 and 18.5 mo respectively.Overall survival was not significantly different between HER2-positive and negative groups(χ 2 = 0.9157,P = 0.3386),but in patients presenting well-differentiated tumors,the overall survival of the HER2-positive group was significantly worse than that of the HER2-negative group(P = 0.0123).In contrast,patients with poorly differentiated and diffuse/mixed subtype gastric cancers showed no significant differences in overall survival associated with HER2.Furthermore,the median survival time of the HER2 positive group did not show any statistically significant differences when compared to the subgroups of gender,age,tumor location,TNM classification,lymph node metastases and distant metastasis.CONCLUSION:Patients with intestinal type gastric cancer(GC),well-differentiated GC and poorly-differentiated GC without lymph node metastasis,may all represent suitable candidates for targeted therapy using Herceptin.

Human Visual Attention Mechanism-Inspired Point-and-Line Stereo Visual Odometry for Environments with Uneven Distributed Features

Visual odometry is critical in visual simultaneous localization and mapping for robot navigation.However,the pose estimation performance of most current visual odometry algorithms degrades in scenes with unevenly distributed features because dense features occupy excessive weight.Herein,a new human visual attention mechanism for point-and-line stereo visual odometry,which is called point-line-weight-mechanism visual odometry(PLWM-VO),is proposed to describe scene features in a global and balanced manner.A weight-adaptive model based on region partition and region growth is generated for the human visual attention mechanism,where sufficient attention is assigned to position-distinctive objects(sparse features in the environment).Furthermore,the sum of absolute differences algorithm is used to improve the accuracy of initialization for line features.Compared with the state-of-the-art method(ORB-VO),PLWM-VO show a 36.79%reduction in the absolute trajectory error on the Kitti and Euroc datasets.Although the time consumption of PLWM-VO is higher than that of ORB-VO,online test results indicate that PLWM-VO satisfies the real-time demand.The proposed algorithm not only significantly promotes the environmental adaptability of visual odometry,but also quantitatively demonstrates the superiority of the human visual attention mechanism.

Modeling Tracer Flow Characteristics in Different Types of Pores: Visualization and Mathematical Modeling

Structure of porous media and fluid distribution in rocks can significantly affect the transport characteristics during the process of microscale tracer flow.To clarify the effect of micro heterogeneity on aqueous tracer transport,this paper demonstrates microscopic experiments at pore level and proposes an improved mathematical model for tracer transport.The visualization results show a faster tracer movement into movable water than it into bound water,and quicker occupancy in flowing pores than in storage pores caused by the difference of tracer velocity.Moreover,the proposed mathematical model includes the effects of bound water and flowing porosity by applying interstitial flow velocity expression.The new model also distinguishes flowing and storage pores,accounting for different tracer transport mechanisms(dispersion,diffusion and adsorption)in different types of pores.The resulting analytical solution better matches with tracer production data than the standard model.The residual sum of squares(RSS)from the new model is 0.0005,which is 100 times smaller than the RSS from the standard model.The sensitivity analysis indicates that the dispersion coefficient and flowing porosity shows a negative correlation with the tracer breakthrough time and the increasing slope,whereas the superficial velocity and bound water saturation show a positive correlation.

An Exploration of Key Features of Major-Country Diplomacy with Chinese Characteristics

China,under the guidance of Xi Jinping Thought on Diplomacy,is making all-round efforts to pursue major-country diplomacy with Chinese characteristics and has achieved a series of historical achievements.Major-country diplomacy with Chinese characteristics significantly diverges from conventional Western major-country diplomacy.It is characterized by a vision that prioritizes national rejuvenation,aims to advance human civilizations,emphasizes the establishment of a new type of international relations,and strives for the building of a human community with a shared future.

Changes in visual performance after implantation of different intraocular lenses

AIM:To evaluate the trending visual performance of different intraocular lenses(IOLs)over time after implantation.METHODS:Ninety-one patients received cataract surgery with implantations of monofocal(Mon)IOLs,segmental refractive(SegRef)IOLs,diffractive(Dif)IOLs,and extendeddepth-of-focus(EDoF)IOLs were included.The aberrations and optical quality collected with iTrace and OQAS within postoperative 6mo were followed and compared.RESULTS:Most of the visual parameters improved over the postoperative 6mo.The postoperative visual acuity(POVA)of the Mon IOL,SegRef IOL,and EDoF IOL groups achieved relative stability in earlier states compared with the Dif IOL group.Nevertheless,the overall visual performance of the 3 IOLs continued to upturn in small extents within the postoperative 6mo.The optical quality initially improved in the EDoF IOL group,then in the Mon IOL,SegRef IOL,and Dif IOL groups.POVA and objective visual performance of the Mon IOL and EDoF IOL groups,as well as POVA and visual quality of the Dif IOL group,improved in the postoperative 1mo and stabilized.Within the postoperative 6mo,gradual improvements were observed in the visual acuity and objective visual performance of the SegRef IOL group,as well as in the postoperative optical quality of the Dif IOL group.CONCLUSION:The visual performance is different among eyes implanted with different IOLs.The findings of the current study provide a potential reference for ophthalmologists to choose suitable IOLs for cataract patients in a personalized solution.

Intelligent 3D garment system of the human body based on deep spiking neural network

Background Intelligent garments,a burgeoning class of wearable devices,have extensive applications in domains such as sports training and medical rehabilitation.Nonetheless,existing research in the smart wearables domain predominantly emphasizes sensor functionality and quantity,often skipping crucial aspects related to user experience and interaction.Methods To address this gap,this study introduces a novel real-time 3D interactive system based on intelligent garments.The system utilizes lightweight sensor modules to collect human motion data and introduces a dual-stream fusion network based on pulsed neural units to classify and recognize human movements,thereby achieving real-time interaction between users and sensors.Additionally,the system incorporates 3D human visualization functionality,which visualizes sensor data and recognizes human actions as 3D models in real time,providing accurate and comprehensive visual feedback to help users better understand and analyze the details and features of human motion.This system has significant potential for applications in motion detection,medical monitoring,virtual reality,and other fields.The accurate classification of human actions contributes to the development of personalized training plans and injury prevention strategies.Conclusions This study has substantial implications in the domains of intelligent garments,human motion monitoring,and digital twin visualization.The advancement of this system is expected to propel the progress of wearable technology and foster a deeper comprehension of human motion.

Sedimentary Characteristics and Response to Climate Change and Human Activities in Shilianghe Reservoir,Jiangsu Province

Reservoirs,as artificial lakes,suffer from silting inevitably since being constructed,the sediments from surrounding environment can provide a continuous record of environmental change.Shilianghe Reservoir,the largest artificial lake in Jiangsu Province,was constructed in 1959,and plays an important role in flood control,irrigation,water supply,and so on.Nevertheless,the silting situation of the reservoir is also quite serious.In this paper,the grain-size distribution of core from Shilianghe Reservoir and its response to environmental changes were studied.It is due to two driving factors:climate variability and human activities.Based on the analysis of the grain size distribution data,the sediments were mainly composed of clayey silt and silty clay with a clear tendency of upward fining.But a grain-size peak appeared at 86 cm,and the sand proportion was also very big,indicating that hydrodynamic force was stronger.There was a consistent trend of change between sediment record in Shilianghe Reservoir and historical precipitation in the basin.According to the dating mark of137 Cs,it can be determined primarily that the abnormal grain-size at 86 cm reflected possibly the rainstorm and flood event occurring in 1970.Human activities reduced the hydrodynamics of depositional environment.Hydraulic projects are direct human activities,and land use/cover changes are indirect human activities.It turned out that sediment yield and sediment load were more and more less,and sedimentation rate showed a decreasing trend.Furthermore,sediments tended to become smaller and had better sorting property.

The Historical Position and Value Dimensions of Human Rights Civilization

Human beings are the mainstay and the ultimate goal of civilization.The history of human civilization is a continuous struggle to realize the respect,liberation,protection,and development of humanity.Human rights are an achievement of humanity and a symbol of progress,and the human rights civilization is an important component of human civilization.Understanding and interpreting human rights from the perspective of human rights civilization means that human rights are not only a concept or an idea but also a grand historical and long-term social practice.Up to now,the development of human rights civilization has roughly experienced four awakening eras:initialization,revolution,popularization,and globalization.In terms of its value dimensions,it has the characteristics of progressiveness,diversity,commonality,inclusiveness,indivisibility,openness,and so on.The historical position of human rights civilization and the development of its value dimensions have shown to the world that human rights are the common wealth of humanity,and human rights belong to all mankind;human rights are historical,concrete,and developmental;the concept of human rights is constantly evolving,and its connotations and categories are constantly expanding;achieving the free and well-rounded development of every person is the highest value realm of human rights civilization.The Chinese modernization endows Chinese civilization with modern strength and opens up new horizons for human rights civilization.The new pattern of human rights civilization to be created by Chinese modernization not only possesses the common characteristics of human rights civilization but also enjoys Chinese characteristics based on its own national conditions,enriching and developing the diversity of human rights civilization for all mankind.

A STUDY OF THE CHARACTERISTICS OF γ-GLUTAMYLTRANSPEPTIDASE OF HUMAN ESOPHAGEAL CANCER

γ-Glutamyltranspeptidase (γ-GT) from human esophageal cancer, normal esophageal mucosa and normal kindney were partially purified and their biochemical and immunological properties were studied. (1) The γ-GT activity of esophageal cancer was higher than that of normal mucosa, yet still much lower than that of normal kidney. (2) The Michaelis constant and optimum pH of esophageal cancer γ-GT were the same as those of normal kidney tissue. (3) After staining of γ-GT activity, two molecular clusters, i.e. 100kD and 380kD γ-GT were shown in esophageal cancer by 4-20% linear gradient PAGE and the lOOkD γ-GT showed higher activity. (4) The γ-GT of esophageal cancer was immunologically identical with normal enzyme in double immunodif-fusion and immunoelectrophoresis. (5) In double lectin-diffusion, affinity column and crossed immuno-affino-electrophoresis, it was demonstrated that the carbohydrate components of γ-GT from esophageal cancer were heterogeneous and rich in D-Mannose, D-Glucose and N-Acetyl-Glucosamine. The relationship between the appearance of 100kD γ-GT cluster and the heterogeneous carbohydrate components will be further studied.

The Communication Analysis Among Stakeholders in Management of Children Education by the Poor Scholarship as Human Capital to Grow Quality Characteristics of Educational Basics

The economic crisis in 1997-1998 increased poverty to 49.5 million,but in 2005 decreased to 35.10 million,then in 2006 increased 39.05 million.The worst communities were workers,dependent families,small farmers and fishermen,informal sector workers,low-level civil servants,and people affected by natural disasters.The research design was cross sectional;the research was in Pangkal Pinang City in January 2016.The data were summarized by interview,observation,documentation,and Focus Group Discussion.Data analyses were flow model,product moment,and Likert scale.The result of the research shows the correlation between how to obtain the poor scholarship and the criteria of obtaining the poor scholarship that is very tight which is 0.453.The relation between the criteria of obtaining the poor scholarship and the determination of the poor scholarship is quite close which is 0.218.The relationship between the determination of the scholarship for poor students and obtaining the poor scholarship is 0.395.The correlation between how to get the poor scholarship and the poor scholarship receiver is quite close that is 0.190.The relationship between the determination of the poor scholarship and the impact of the poor scholarship is quite close that is 0.171.The relationship between using of the poor scholarship and the poor scholarship receiver is very close that is 0.297.The relation between the poor receiver and the impact of poor the scholarship is 0.270.

The Development Path for Human Rights with Chinese Characteristics

Like most countries in the world, China supports the ideal of human rights de- picted and advocated in the Universal Declaration of Human Rights and other international docu- ments and agrees with the idea that human rights should be universal. However, China also holds that to better realize the common goals of human rights requires that each coun- try explore and find the best and most efficient way in accordance with its own conditions. One of the reasons for the fast development of human rights in China since its reform and opening-up is that China has chosen a development path for human rights according to its own conditions. The path fits the conditions of China and therefore efficiently promotes the realization of universal human rights.

Visualization of Understanding of Media Characteristics Using Analytic Hierarchy Process

The purpose of this study is to design a tool, adapted to students＇ individual contexts and to enable students to reflect on their understanding of media characteristics. AHP （analytic hierarchy process） is a structured technique for organizing and analyzing complex decisions. Using AHP, students have to define appropriate criteria and priorities for using media. It is expected that students＂ understanding of the characteristics of different types of media will emerge through reflection. Seventy two university students took part in this research. They were asked to prioritize their ways.of obtaining information about current affairs using sets of media such as TV, books, newspapers and web pages, Twitter and Facebook. AHP enables us to visualize a ＂real＂ understanding of media characteristics and students can reflect on that basis. As far as ＂information sources and media＂ is concerned, a few students indicated that it was the information source itself that was important rather than the type of media. Our tool fulfils the role of encouraging this type of reflection.

A STUDY OF THE BIOLOGICAL CHARACTERISTICS OF HUMAN HEPATOMA XENOGRAFTS IN NUDE MICE AFTER IRRADIATION

Cell growth kinetics and changes in AFP in nude mice with human hepatoma xenografts were evaluated using the flow cytometry method. After receiving 10 Gy of radiation, the mice showed a marked delay in tumor growth; approximately 1 Gy of radiation caused a tumor growth delay of one day. Irradiation altered various phases of the cell cycle. An acute and temporary block of G2 cells was characteristic; FCM measurements demonstrated that about 58% of cells were blocked in the G2 phase and this blocking effect lasted 90 hours after an irradiation of 10 Gy. This indicated that human hepatoma xenografts in nude mice were quite sensitive to irradiation. It was also noted that the AFP decreased for 96 hours after irradiation. Changes in G2 cells after irradiation may be closely related to changes in AFP.

For a Socialist Theoretical System for Human Rights with Chinese Characteristics

I.The Necessity and Feasibility for Developing a Socialist Theoretical System for Human Rights with Chinese Characteristics Development of such a system is needed to ensure success of the social transformation and transition ongoing up in China

CHARACTERISTICS OF MUCINS AND CEA IN GLOBOID DYSPLASTIC CELLS OF HUMAN STOMACH AND ITS RELATIONSHIP WITH SIGNET RING CELL CARCINOMA

Fourty-three cases of globoid dysplasia and signet ring cell carcinoma were stained by mucin and CEA (ABC method). It was found that there were three kinds of mucins (neutral, sialo and sulphomucin in both globoid dysplastic cells and signet ring cells. The percentages of the three kinds of mucins seen in the two kinds of cells were not much different. It was indicated that the altered mucins in the gastric epithelial cells must be a sign of dedifferentiation of the cells and the results of malfunction. The globoid dysplasia type I mainly contained neutral mucin, whereas type II, the acid mucin was predominant, especially the sulphomucin. The CEA positive reaction became stronger as the atypia being remarkable, and the characteristics of distribution of CEA positive particles were similar in the two kinds of cells namely, randomly or disorderly in the cells. Based on the analysis of the results, a conclusion can be made that the variety of mucins in globoid dysplastic cells can be used as a reference point in classification and is not much significant in grading, but the amount of CEA positive matter can be a reference point in grading. The globoid dysplasia is such a lesion with special features in morphology and function manifested in the process of de-differentiation towards signet ring cell carcinoma following the successive action of carcinogens upon the cells of gastric epithelium.

Give Play to the Role of NGOs Create a New Situation for the Cause of Human Rights with Chinese Characteristics

It’s a great pleasure to meet you in Beijing and solemnly commemorate the 70th anniversary of the universal Declaration of Human Rights. First, on behalf of the China Foundation for Human Rights Development, I would like to express my sincere gratitude and heartfelt thanks to all the friends who have been committed to supporting and promoting the development of China’s human rights cause over the years.

Characteristics of Human Rights Education In Chinese Schools

As an educator, I have been keen on human rights education in Chinese schools. Tbrough visits to schools ranging from those at the primary level to schools of higher learning, I have found that education of the young in human rights is fairly developed in the country and conducted in a comprehensive, scientific manner. We are justified to say that a complete system of human rights education is already in place in the country.