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Preparedness,knowledge,and perception of nursing students about climate change and its impact on human health in India
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作者 Ramya Kundayi RAVI Priya BABY +3 位作者 Nidhin ELIAS Jisa George THOMAS Kathyayani Bidadi VEERABHADRAIAH Bharat PAREEK 《Regional Sustainability》 2024年第1期107-118,共12页
Higher education plays an important role in all aspects of sustainability.Infusing climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and ... Higher education plays an important role in all aspects of sustainability.Infusing climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and sustainability actions to build resilient health systems.In this study,we evaluated the preparedness,knowledge,and perception regarding climate change and its impact on human health among Indian nursing students.A quantitative descriptive survey was conducted among 644 undergraduate nursing students studying in three institutes in the southern,northern,and western parts of India.We used a structured online questionnaire with established validity and reliability to collect data.The data were analyzed using Statistical Package for the Social Sciences version 26 software.The results showed that more than half of the students reported experiencing excessive increase(362;56.2%)and decrease(374;58.1%)in temperature in recent years.Though more than three quarters of the students(494;76.7%)accepted the general truth that climate change is mainly caused by human activities,only less than half of the students(309;48.0%)perceived the impact of climate change to be high.Three quarters of the students(483;75.0%)had a high level of knowledge regarding climate change.The students who had a high level of knowledge about climate change exerted a high perceived impact of climate change(χ^(2)=75.47;P<0.01).More than half of the students(50.9%)felt that they needed information about climate change to be included in the nursing curriculum,and only one sixth of the students(16.1%)were highly confident about engaging in climate change-related conversation with patients.Most of the students who participated in the study had basic knowledge about climate change and its impact on human health.However,there is an observed gap between knowledge and their preparedness and confidence to engage in climate change actions.Hence,we propose to strengthen the nursing curriculum by integrating various curricular and co-curricular activities related to climate change,so that future nurses are empowered to become climate change advocates. 展开更多
关键词 Climate change CURRICULUM Nursing students human health INDIA
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Ethics of Human Resources Management in the Cameroonian Health System, Medical Nomadism and the Ineffectiveness of the Fight against High Blood Pressure
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作者 Jean Ndibi Abanda Anicet Onana Akoa +2 位作者 Désiré Tchoffo Ulrich Dama Pierre Yassa Yoniene 《Health》 2024年第1期9-21,共13页
Context/objectives: The fight against Chronic Non-Communicable Diseases (NCDs) is a long-term undertaking, which requires available, motivated and well-managed human resources (HR). The administrative management of sk... Context/objectives: The fight against Chronic Non-Communicable Diseases (NCDs) is a long-term undertaking, which requires available, motivated and well-managed human resources (HR). The administrative management of skills on both qualitative and quantitative levels is one of the essential functions of a health system. To better implement policies of fight against High Blood Pressure (HBP) and other chronic diseases, it is important to establish strategies to retain health personnel. This loyalty requires favorable working conditions and consideration of the contribution-reward couple. Good working conditions are likely to reduce the phenomenon of medical nomadism;conversely, poor HR management can contribute to their exodus towards exotic “green pastures”, thus leading to an additional crisis in the Cameroonian health system. The fight against HBP is a complex, multifaceted and multifactorial reality that requires appropriate management model for all types of resources mainly HR. The main objective of this research is to show the impact of poor management of human resources in Cameroon health system on medical nomadism and the ineffectiveness of the fight against High Blood Pressure. Method: A cross-sectional descriptive survey among five hundred (500) health facilities in the center region of Cameroon has been conducted. A stratified probabilistic technique has been used, and the number of health facilities to be surveyed has been determined using the “sample size estimation table” of Depelteau. The physical questionnaires have been printed and then distributed to data collectors. After data collection, the latter were grouped during processing in Excel sheets. The Chi-square test was used for data with a qualitative value and that of Kolmogorov-Sminorf for data with a quantitative value to assess the normality and reliability of data. The Crochach’s Alpha reliability test allowed us to have a summary of the means and variances and then to search for intragroup correlations between variables. Descriptive analysis was possible with the XLSTAT 2016 software. Results: 43.60% of Health Facilities (HF) managers were unqualified. 82.20% of HF managers have staff in a situation of professional insecurity. They are mainly contractual (49.00), decision-making agents (24.40%), casual agents (08.80). The proportion of unstable personnel is average of 22.00% and very unstable, 12.00%. 展开更多
关键词 ETHICs human Resources Management Cameroonian health system Medical Nomadism Ineffectiveness High Blood Pressure
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Impact of Plastic Waste on the Human Health in Low-Income Countries: A Systematic Review
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作者 Ramde Wendkoaghenda Sophie Gbandama Koffi Kouame Pacome +5 位作者 Gansore Aminata Camara Kelety Tolno Barthélemy Assogba Ange Wenceslas Vinciale Niare Boubacar Patrice Ngangue 《Journal of Environmental Protection》 2024年第5期572-595,共24页
Background: Plastic pollution is the accumulation of waste composed of plastic and its derivatives all over the environment. Whether in the form of visible garbage or microparticles, as it slowly degrades, plastic pol... Background: Plastic pollution is the accumulation of waste composed of plastic and its derivatives all over the environment. Whether in the form of visible garbage or microparticles, as it slowly degrades, plastic pollution poses significant threats to terrestrial and aquatic habitats and the wildlife that call them home, whether through ingestion, entanglement or exposure to the chemicals contained in the material. Unfortunately, there is a lack of documentation on the impact of plastic waste on human health in low- and middle-income countries (LMICs). Methods: We searched five electronic databases (PubMed, Embase, Global Health, CINAHL and Web of Science) and gray literature, following the preferred reporting elements for systematic reviews and meta-analyses (PRISMA), for the impact of plastic waste on human health in developing countries. We included quantitative and qualitative studies written in English and French. We assessed the quality of the included articles using the Mixed Methods Appraisal tool (MMAT). Results: A total of 3779 articles were initially identified by searching electronic databases. After eliminating duplicates, 3167 articles were reviewed based on title and abstract, and 26 were selected for full-text review. Only three articles were retained. The three articles dealt with practices likely to lead to oral exposure to plastic chemicals in human health, as well as the level of awareness of participants concerning the possible impact of plastic on human health, namely, the use of plastic baby bottles, the use of microwaves to cook food and reheat precooked food, the use of plastic bottles to store water in the refrigerator, water purifier containers with plastic bodies and plastic lunch boxes, the reuse of plastic bags and the inadequacy of treatment facilities. Conclusion: Plastic waste poses different risks to human health at every stage of its life cycle. Hence, strategies must be adopted to raise public awareness of the dangers of plastic waste to their health. Trial registration: The review protocol is registered in the PROSPERO international prospective register of systematic reviews (ID = CRD42023409087). 展开更多
关键词 human Population Plastic Waste health Impact Low-Income-Countries (humans Iatrogenic Disease PLAsTICs POLICY RECYCLING Waste Management)
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Arsenic and fluoride co-enrichment of groundwater in the loess areas and associated human health risks:A case study of Dali County in the Guanzhong Basin
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作者 Rui-ping Liu Fei Liu +5 位作者 Hua-qing Chen Yu-ting Yang Hua Zhu You-ning Xu Jian-gang Jiao Refaey M El-Wardany 《China Geology》 CAS CSCD 2024年第3期445-459,共15页
This study aims to reveal the occurrence and origin of typical groundwater with high arsenic and fluoride concentrations in the loess area of the Guanzhong Basin—a Neogene faulted basin.Key findings are as follows:(1... This study aims to reveal the occurrence and origin of typical groundwater with high arsenic and fluoride concentrations in the loess area of the Guanzhong Basin—a Neogene faulted basin.Key findings are as follows:(1)Groundwater samples with high arsenic and fluoride concentrations collected from the loess area and the terraces of the Weihe River accounted for 26%and 30%,respectively,of the total samples,with primary hydrochemical type identified as HCO_(3)-Na.The karst and sand areas exhibit relatively high groundwater quality,serving as preferred sources for water supply.It is recommended that local governments fully harness groundwater in these areas;(2)groundwater with high arsenic and fluoride concentrations in the loess area and the alluvial plain of rivers in Dali County is primarily distributed within the Guanzhong Basin,which represents the drainage zone of groundwater;(3)arsenic and fluoride in groundwater originate principally from natural and anthropogenic sources;(4)the human health risk assessments reveal that long-term intake of groundwater with high arsenic and fluoride concentrations pose cancer or non-cancer risks,which are more serious to kids compared to adults.This study provides a theoretical basis for the prevention and treatment of groundwater with high arsenic and fluoride concentrations in loess areas. 展开更多
关键词 ARsENIC FLUORIDE GROUNDWATER Cancer risk Kid and adult human health risk assessment Hydrogeological survey engineering Environmental geological survey engineering Loess areas
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A study on the cognitive status of human papillomavirus among adult males in Tianjin based on the health belief model
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作者 Ming Ma Fei-Fei Hong +3 位作者 Yu Liu Xin-Ran Huang Qi-Yun Ma Peng-Xi Liu 《Infectious Diseases Research》 2024年第3期1-8,共8页
Background:To understand the health beliefs and knowledge of human papillomavirus among adult males in Tianjin.Methods:An online questionnaire survey was conducted from 18 January 2023 to 6 March 2023 using snowball s... Background:To understand the health beliefs and knowledge of human papillomavirus among adult males in Tianjin.Methods:An online questionnaire survey was conducted from 18 January 2023 to 6 March 2023 using snowball sampling method.Analyze the health belief scores and human papillomavirus(HPV)and HPV vaccine knowledge scores of adult males in Tianjin,and analyze their influencing factors.Results:A total of 388 adult males in Tianjin were surveyed,with an average total score of 3.23±0.04 for their health beliefs.Among them,the average scores for perceived severity,perceived susceptibility,perceived impairment,perceived benefit,and self-efficacy were 3.41±1.05,2.37±1.20,2.96±1.00,3.51±0.90,and 3.36±1.08,respectively.Multiple linear regression analyses showed education was a factor influencing health beliefs.The average total score of knowledge is 64.09±15.62,with 277 people scoring above 60,and a pass rate of 71.4%.Through multiple linear regression analysis,education level,emotional status,whether disease testing has been done,and whether family and friends have been diagnosed with HPV positive are the main influencing factors.Conclusion:The awareness rate of HPV among adult males in Tianjin is still acceptable,but there are still misconceptions.The overall level of health beliefs is moderate,and the perceived susceptibility level is low.It is necessary to strengthen health education on HPV related knowledge for males and improve their cognitive level. 展开更多
关键词 human papillomavirus health Beliefs COGNITION adult male human papillomavirus vaccine
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Development of Human Rights-Based Practices in Psychiatry from People Living with Mental Health Problems During Involuntary Hospitalization or Treatment - A Secondary Publication
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作者 David Pelosse Pierre Pariseau-Legault 《Journal of Clinical and Nursing Research》 2024年第3期247-255,共9页
This article presents the research protocol of an interpretative phenomenological study that aims to understand the lived experiences of coercion and human rights-based practices in psychiatry from the perspectives of... This article presents the research protocol of an interpretative phenomenological study that aims to understand the lived experiences of coercion and human rights-based practices in psychiatry from the perspectives of people living with mental health problems during involuntary hospitalization or treatment.This qualitative study used an interpretative phenomenological analysis design.In-depth,one-on-one interviews along with a socio-demographic questionnaire were conducted with approximately 10 participants.Data analysis was followed by an iterative and hermeneutic emergence coding process.By centering human rights-based practices on the lived experiences of people living with mental health problems who encountered coercion,this study highlighted the contributing and limiting factors to the recognition of human rights in nursing practices.This study also promoted the development of nursing knowledge and practices that can significantly contribute to an individual’s recovery process. 展开更多
关键词 Mental health Coercion support human rights Users
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Effectiveness of onsite and online education in enhancing knowledge and use of human immunodeficiency virus pre-and postexposure prophylaxis
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作者 Ying Shao Mei Zhang +10 位作者 Li-Jun Sun Hong-Wei Zhang An Liu Xi Wang Ruo-Lei Xin Jian-Wei Li Jiang-Zhu Ye Yue Gao Zhang-Li Wang Zai-Cun Li Tong Zhang 《World Journal of Clinical Cases》 SCIE 2024年第22期5042-5050,共9页
BACKGROUND Enhancing awareness and use of pre-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)is vital to curb human immunodeficiency virus(HIV)spread.High-risk behaviors prevalent among sexually transmitte... BACKGROUND Enhancing awareness and use of pre-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)is vital to curb human immunodeficiency virus(HIV)spread.High-risk behaviors prevalent among sexually transmitted infection clinic outpatients underscore the need for increased PrEP/PEP education in this group.AIM To investigate the effects of both onsite and online health education on the knowledge of,and willingness to use,PrEP and PEP among individuals receiving PEP services.METHODS Participants were drawn from a cohort study on PEP service intervention at an STD/AIDS outpatient clinic in designated HIV/AIDS hospitals in Beijing,conducted from January 1 to June 30,2022.Health education was provided both onsite and online during follow-up.Surveys assessing knowledge of,and willingness to use,PrEP/PEP were administered at baseline and again at 24 wk post-intervention.RESULTS A total of 112 participants were enrolled in the study;105 completed the follow-up at week 24.The percentage of participants with adequate knowledge of,and willingness to use,PrEP significantly increased from 65.2%and 69.6%at baseline to 83.8%and 82.9%at the end of the intervention(both P<0.05).Similarly,those with adequate knowledge of,and willingness to use,PEP increased from 74.1%and 77.7%at baseline to 92.4%and 89.5%at week 24(P<0.05).Being between 31 years and 40 years of age,having a postgraduate degree or higher,and reporting a monthly expenditure of RMB 5000 or more were found to be significantly associated with knowledge of PrEP and PEP(both P<0.05).CONCLUSION The findings show that both onsite and online health education significantly improved the knowledge of,and increased willingness to use,PrEP and PEP in individuals utilizing PEP services. 展开更多
关键词 human immunodeficiency virus Pre-exposure prophylaxis Post-exposure prophylaxis health education INTERVENTION
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Eco-toxicity and health risk assessment of polycyclic aromatic hydrocarbons in surface sediments of Burullus Lake in Egypt
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作者 Hanan E Osman Mohamed H E El-Morsy Hazem T Abd El-Hamid 《China Geology》 CAS CSCD 2024年第3期460-468,共9页
Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous environmental contaminants of growing concern due to their potential ecological and human health risks.This study presents a comprehensive assessment of PAHs contam... Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous environmental contaminants of growing concern due to their potential ecological and human health risks.This study presents a comprehensive assessment of PAHs contamination in the surface sediments of Burullus Lake,a vital and second largest delta lake in Egypt.The aim was to evaluate the eco-toxicity and potential health risks associated with the presence of these compounds.Surface seven sediment samples were collected from various drains in the southern part of Burullus Lake.Soxhlet extraction method was employed to extract PAHs(16PAHs)from the sediment sample.Analytically,target compounds were located using HPLC.The results showed that samples contained PAHs levels ranging from 0.038×10^(-6)to 0.459×10^(-6),which is considered heavily polluted by the European standard for PAHs pollution.Additionally,there was no apparent source of PAHs in the ElKhashah drain or the Brinbal Canal,as HPLC found none of the compounds.The most prevalent compound in sediment samples along the study area was fluoranthene.The diagnostic indices in the present study indicated that the hydrocarbons in the region originated from pyrolytic and man-made sources along the drains of Burullus Lake.The principal component analysis(PCA)and diagnostic ratios revealed that coal combustion and pyrolytic sources were responsible for the PAHs contamination in the surface sediments.The non-carcinogenic risk(HI),which is the product of the HQs for the adult and child populations,respectively,was calculated.HI values under 1,therefore,demonstrated that they had no carcinogenic effects on human health.TEQs and MEQs in the sediments of Burullus Lake do not have a cancer-causing impact on people.For the safety of nearby wildlife,aquatic life,and people,all activities that raise petroleum hydrocarbon levels in Burullus Lake must be adequately regulated and controlled.According to the ecological risk assessment,there is little chance that PAHs will be found in the sediments of Burullus Lake.This study underscores the urgent need for effective pollution control measures and regular monitoring of PAHs levels in Burullus Lake sediments to protect the aquatic ecosystem and public health.It also highlights the importance of considering eco-toxicity and human health risks in integrated risk assessments of PAHs-contaminated environments. 展开更多
关键词 Polycyclic aromatic hydrocarbons Diagnostic indices TOXICITY Delta lake sediment Burullus Lake human health risk Aquatic ecosystem HPLC Coal combustion
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Smart Healthcare Activity Recognition Using Statistical Regression and Intelligent Learning
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作者 K.Akilandeswari Nithya Rekha Sivakumar +2 位作者 Hend Khalid Alkahtani Shakila Basheer Sara Abdelwahab Ghorashi 《Computers, Materials & Continua》 SCIE EI 2024年第1期1189-1205,共17页
In this present time,Human Activity Recognition(HAR)has been of considerable aid in the case of health monitoring and recovery.The exploitation of machine learning with an intelligent agent in the area of health infor... In this present time,Human Activity Recognition(HAR)has been of considerable aid in the case of health monitoring and recovery.The exploitation of machine learning with an intelligent agent in the area of health informatics gathered using HAR augments the decision-making quality and significance.Although many research works conducted on Smart Healthcare Monitoring,there remain a certain number of pitfalls such as time,overhead,and falsification involved during analysis.Therefore,this paper proposes a Statistical Partial Regression and Support Vector Intelligent Agent Learning(SPR-SVIAL)for Smart Healthcare Monitoring.At first,the Statistical Partial Regression Feature Extraction model is used for data preprocessing along with the dimensionality-reduced features extraction process.Here,the input dataset the continuous beat-to-beat heart data,triaxial accelerometer data,and psychological characteristics were acquired from IoT wearable devices.To attain highly accurate Smart Healthcare Monitoring with less time,Partial Least Square helps extract the dimensionality-reduced features.After that,with these resulting features,SVIAL is proposed for Smart Healthcare Monitoring with the help of Machine Learning and Intelligent Agents to minimize both analysis falsification and overhead.Experimental evaluation is carried out for factors such as time,overhead,and false positive rate accuracy concerning several instances.The quantitatively analyzed results indicate the better performance of our proposed SPR-SVIAL method when compared with two state-of-the-art methods. 展开更多
关键词 Internet of Things smart health care monitoring human activity recognition intelligent agent learning statistical partial regression support vector
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Healthcare Worker-Related Factors Contributing to Tuberculosis Treatment Non-Adherence among Patients in Kisumu East Sub-County
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作者 Marlyn Ochieng Jackline Nyaberi +1 位作者 Susan Mambo Charles Wafula 《Journal of Tuberculosis Research》 2024年第1期13-33,共21页
Background: Treatment non-adherence poses significant risks to health outcomes and impedes the health system’s efficiency, hence curtailing progress towards the end Tuberculosis (TB) strategy under SDG 3.3. Despite i... Background: Treatment non-adherence poses significant risks to health outcomes and impedes the health system’s efficiency, hence curtailing progress towards the end Tuberculosis (TB) strategy under SDG 3.3. Despite interventions to address TB treatment non-adherence, Kenya still reports high TB treatment non-adherence rates of 35% and consequently poor treatment outcome rates. Health Care Workers (HCWs) play a critical role in linking the population to health services, yet little is known of their influence on patients’ TB treatment non-adherence in Kenya. Objective: To analyze HCW-related factors associated with TB treatment non-adherence among patients in Kisumu East Sub-County. Methods: Health facility-based analytical cross-sectional mixed-method study. A Semi-structured questionnaire on treatment adherence and patients’ perceptions of HCWs during the clinic visit was administered to 102 consenting adult (out of a total census of 107 adults) drug-susceptible TB patients. 12 purposively selected HCWs by rank from 6 health facilities participated in Key Informant Interview sessions. Medication adherence was measured using the Morisky Medication Adherence Scale and then expressed as a dichotomous variable. Quantitative analysis utilized STATA version 15.1 while qualitative deductive thematic analysis was done using NVIVO version 14. Results: TB treatment non-adherence rate of 26% (CI: 18% - 36%) was recorded. Overall, patients who felt supported in dealing with the illness were 8 times more likely to adhere to treatment compared to those who were not (aOR = 7.947, 95% CI: 2.214 - 28.527, p = 0.001). Key HCW related factors influencing adherence to treatment included: friendliness (cOR = 4.31, 95% CI: 1.514 - 12.284, p = 0.006), respect (cOR = 6.679, 95% CI: 2.239 - 19.923, p = 0.001) and non-discriminatory service (cOR = 0.1478, 95% CI: 0.047 - 0.464, p = 0.001), communication [adequacy of consultation time (cOR = 6.563, 95% CI: 2.467 - 17.458, p = 0.001) and patients’ involvement in their health decisions (cOR = 3.02 95% CI: 1.061 - 8.592, p = 0.038)] and education and counselling (cOR = 4.371, 95% CI: 1.725 - 11.075, p = 0.002). Conclusion: The study results underline importance of patient-centered consultation for TB patients and targeted education and counselling for improved treatment adherence. 展开更多
关键词 TUBERCULOsIs Treatment Adherence human Resources for health
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Health risk assessment of trace metal(loid)s in agricultural soils based on Monte Carlo simulation coupled with positive matrix factorization model in Chongqing, southwest China
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作者 MA Jie CHU Lijuan +3 位作者 SUN Jing WANG Shenglan GE Miao DENG Li 《Journal of Mountain Science》 SCIE CSCD 2024年第1期100-112,共13页
This study aimed to investigate the pollution characteristics, source apportionment, and health risks associated with trace metal(loid)s(TMs) in the major agricultural producing areas in Chongqing, China. We analyzed ... This study aimed to investigate the pollution characteristics, source apportionment, and health risks associated with trace metal(loid)s(TMs) in the major agricultural producing areas in Chongqing, China. We analyzed the source apportionment and assessed the health risk of TMs in agricultural soils by using positive matrix factorization(PMF) model and health risk assessment(HRA) model based on Monte Carlo simulation. Meanwhile, we combined PMF and HRA models to explore the health risks of TMs in agricultural soils by different pollution sources to determine the priority control factors. Results showed that the average contents of cadmium(Cd), arsenic (As), lead(Pb), chromium(Cr), copper(Cu), nickel(Ni), and zinc(Zn) in the soil were found to be 0.26, 5.93, 27.14, 61.32, 23.81, 32.45, and 78.65 mg/kg, respectively. Spatial analysis and source apportionment analysis revealed that urban and industrial sources, agricultural sources, and natural sources accounted for 33.0%, 27.7%, and 39.3% of TM accumulation in the soil, respectively. In the HRA model based on Monte Carlo simulation, noncarcinogenic risks were deemed negligible(hazard index <1), the carcinogenic risks were at acceptable level(10^(-6)<total carcinogenic risk ≤ 10^(-4)), with higher risks observed for children compared to adults. The relationship between TMs, their sources, and health risks indicated that urban and industrial sources were primarily associated with As, contributing to 75.1% of carcinogenic risks and 55.7% of non-carcinogenic risks, making them the primary control factors. Meanwhile, agricultural sources were primarily linked to Cd and Pb, contributing to 13.1% of carcinogenic risks and 21.8% of non-carcinogenic risks, designating them as secondary control factors. 展开更多
关键词 Monte Carlo simulation health risk assessment Trace metal(loid)s Positive matrix factorization Agricultural soils
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One-step cell biomanufacturing platform:porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo
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作者 Lin Feng Da Li +10 位作者 Yao Tian Chengshun Zhao Yun Sun Xiaolong Kou Jun Wu Liu Wang Qi Gu Wei Li Jie Hao Baoyang Hu Yukai Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期458-464,共7页
Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a p... Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a promising treatment for Parkinson’s disease.However,transplanted cells can be injured by mechanical damage during handling and by changes in the transplantation niche.Here,we developed a one-step biomanufacturing platform that uses small-aperture gelatin microcarriers to produce beads carrying midbrain dopaminergic progenitor cells.These beads allow midbrain dopaminergic progenitor cell differentiation and cryopreservation without digestion,effectively maintaining axonal integrity in vitro.Importantly,midbrain dopaminergic progenitor cell bead grafts showed increased survival and only mild immunoreactivity in vivo compared with suspended midbrain dopaminergic progenitor cell grafts.Overall,our findings show that these midbrain dopaminergic progenitor cell beads enhance the effectiveness of neuronal cell transplantation. 展开更多
关键词 axonal integrity cell cryopreservation cellular environment cellular niche cell replacement therapy dopaminergic progenitors human pluripotent stem cell mechanical damage neuronal cell delivery Parkinson’s disease small-aperture gelatin microcarriers
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The Alzheimer’s Dementia Patients’ Observed Illness Course and Experience in Ghana and Care Lessons to Be Learnt: A Mental Health Professional’s Perspective
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作者 Albert M. E. Coleman 《Open Journal of Psychiatry》 2024年第2期91-106,共16页
Alzheimer’s disease (AD) and associated dementia patient numbers continue to increase globally with associated economic costs to healthcare systems. Of note is the increase in numbers in lower and middle-income count... Alzheimer’s disease (AD) and associated dementia patient numbers continue to increase globally with associated economic costs to healthcare systems. Of note is the increase in numbers in lower and middle-income countries (LMICs) including Sub-Saharan African (SSA) countries, which already face challenges with their health budgets from communicable and non-communicable diseases. Ghana, an SSA country, faces the problem of healthcare budgetary difficulties and the additional impact of AD as a consequence of increasing population strata of old aged persons (OAPs) due to the demographic transition effect. This article uses examples of known patients’ illness courses to give a perspective on the lived experience of patients with dementia (PWD) in Ghana, living amongst a populace with a culture of stigmatization of PWD, and a relatively fragile public mental health system (PMHS) for those with mental illness, including AD. The lived experience of AD patients is characterised by stigmatisation, discrimination, non-inclusiveness, diminished dignity and human rights abuses in the face of their mental disability, and eventually death. This article is an advocacy article giving voice to the voiceless and all persons suffering from AD and other dementias in Ghana, whilst pleading for a call to action from healthcare professionals and responsible state agencies. 展开更多
关键词 Alzheimer’s Dementia PATIENTs Ghana sTIGMATIZATION Discrimination human Rights DIGNITY
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Pioneering a New Realm of Human Rights Civilization in the Chinese Path to Modernization——An Overview of the Symposium on“The Chinese Path to Modernization and the Promotion of Free and Comprehensive Human Development”
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作者 王新怡 黄安杰 QIAN chuijun(Translated) 《The Journal of Human Rights》 2024年第2期476-481,共6页
On October 14,2023,a symposium themed“The Chinese Path to Modernization and the Promotion of Free and Comprehensive Human Development”was held in Changchun,Jilin Province,China.More than fifty experts,scholars,and r... On October 14,2023,a symposium themed“The Chinese Path to Modernization and the Promotion of Free and Comprehensive Human Development”was held in Changchun,Jilin Province,China.More than fifty experts,scholars,and researchers from national institutions and universities engaged in discussions and exchanges on human rights on the Chinese path to modernization,including the path,practice,knowledge systems,and civilization forms of human rights.This symposium played a significant role in advancing the construction of the disciplinary system,academic system,and discourse system of human rights in China. 展开更多
关键词 Chinese path to modernization Chinese human rights civilization China’s indigenous human rights knowledge system free and comprehensive human development
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A Study of Health Prescribing for Children with Tourette’s Disorders in Children’s Health Education Specialty Care Clinics
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作者 Wenping Yang Le Wang +2 位作者 Sha Wang Nannan Ma Li Mei 《Journal of Clinical and Nursing Research》 2024年第7期261-266,共6页
Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Met... Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Methods:Applying the evidence-based nursing model and nursing intervention theory based on the survey research by searching China Knowledge Network,Wanfang Database and Wipro Chinese Science and Technology Journal Database,the study collected the literature on the health prescription intervention research in children’s Tourette’s disorders health education in children’s health education of specialized nursing outpatient clinic for review and combined with the specialty characteristics to formulate“Children’s Tourette’s Disorder Health Education Prescription.”Results:Tourette’s syndrome in children is a common pediatric neurological disorder,mainly manifested as involuntary,rapid and repeated muscle twitching and vocal tics,which brings serious psychological pressure and life disturbance to the affected children.Conclusion:For children with Tourette’s syndrome,healthcare professionals should give enough care and understanding to the children and their parents,provide timely and effective health education to them,help them improve their bad behavioral habits,establish correct cognitive attitudes,enhance self-confidence,improve patient compliance,reduce the frequency of recurrence,reduce the incidence of complications and promote children’s physical and mental health development. 展开更多
关键词 Children’s health education specialty care clinic Childhood Tourette’s disorder health prescription
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Contamination and human health risk assessment of heavy metal(loid)s in topsoil and groundwater around mining and dressing factories in Chifeng,North China
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作者 Di Zhao Qiang Wu +9 位作者 Yifan Zeng Juan Zhang Aoshuang Mei Xiaohui Zhang Shuai Gao Hanyuan Wang Honglei Liu Yong Zhang Shuai Qi Xu Jia 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第1期33-47,共15页
Chifeng is a concentrated mining area for non-ferrous metal minerals,as well as a key prevention and control area for heavyduty enterprises.This situation necessitates an efective ecological and human health risk asse... Chifeng is a concentrated mining area for non-ferrous metal minerals,as well as a key prevention and control area for heavyduty enterprises.This situation necessitates an efective ecological and human health risk assessment of heavy metal(loid)s driven by the wide distribution of metal ore processing,mining,and smelting factories in Hexigten Banner and Bairin Left Banner.We conducted surveys to assess the levels of heavy metal(loid)s(Cr,As,Pb,Cd,and Hg)in the topsoil and groundwater of the areas.The results indicated that the concentrations of As,Cd,and Pb in partial soil samples exceeded the environmental quality standards of Grade II.Based on contamination assessments,such as geoaccumulation indices and pollution indices,we inferred that Cd,Pb,and As were primary pollutants in topsoil.Potential ecological risks when considered as part of the average risk indices(RI)are up to 1626.40 and 2818.76,respectively,in the two areas.Comparative analysis revealed that Cd posed a very high potential ecological risk,followed by As.Moreover,the evaluation showed that the three exposure pathways of carcinogenic and non-carcinogenic risk followed a descending order:inhalation>ingestion>dermal contact,except for Pb.Arsenic in topsoil posed a potential non-carcinogenic risk to human health,while there were no adverse efects of As in groundwater.In addition,the average total carcinogenic risk for As in the two areas,as well as the risk of Pb in the topsoil of Bairin Left Banner and all the fve heavy metal(loid)s in groundwater,exceeded human tolerance.Pb–Zn mines caused higher human health risks.In addition,the tandem contamination of heavy metal(loid)s in soil and groundwater was not obvious.This research study provides a basis for pollution remediation to control heavy industry-induced ecological and health risks of heavy metal(loid)s. 展开更多
关键词 Heavy metal(loid)s Contamination indices Ecological risks human health risks Chifeng
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The Place of Human Resource Management in Lagos State Healthcare Delivery: A Statistical Overview
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作者 Maxwell Obubu Nkata Chuku +7 位作者 Alozie Ananaba Rodio Diallo Firdausi Umar Sadiq Emmanuel Sambo Oluwatosin Kolade Tolu Oyenkanmi Kehinde Olaosebikan Oluwafemi Serrano 《Health》 2023年第3期251-265,共15页
Background: Behind every great system is an organized team;this is especially true in the healthcare industry, where a dedicated human resources team can effectively recruit employees, train staff, and implement safet... Background: Behind every great system is an organized team;this is especially true in the healthcare industry, where a dedicated human resources team can effectively recruit employees, train staff, and implement safety measures in the workplace. The importance of human resources in the healthcare industry cannot be overstated, with benefits ranging from providing an orderly and effectively run facility to equipping staff with the most accurate and up-to-date training. Proper human resources management is critical in providing high-quality health care. A refocus on human resources management in healthcare requires more research to develop new policies. Effective human resources management strategies are greatly needed to achieve better outcomes and access to health care worldwide. Methods: This study leveraged NOI Polls census data on Health Facility Assessment for Lagos State. One thousand two hundred fifty-six health care facilities were assessed in Lagos State;numbers of Health workers were documented alongside their area of specialization. Also, demographic characterizations of the facilities, such as LGA, Ownership type, Facility Level Care, and Category of the facility, were also documented. Descriptive statistics alongside cross tabulation was done to present the various area of specialization of the health workers. Multiple response analysis was done to understand the distribution of human resources across the health facilities. At the same time, Chi-square and correlation tests were conducted to test the independence of various categories recorded while understanding the relationships among selected specialties. Results: The study revealed that Nurses were the most common health specialist in the Lagos State health facilities. At the same time, Gynecologists and General surgeons are the two medical specialists mostly common in health facilities. Midwives are the second most common health specialist working full time, while Generalist medical doctors make up the top three health specialists working full time. Nurses and Midwives had the highest number in Lagos State, while Pulmonologists were currently the lowest human resource available in Lagos State health care system. It was also noted that health facility distribution across Lagos’s urban and rural areas was even. In contrast, distribution based on other factors such as ownership type, Facility level of care, and facility category was slightly skewed. Conclusion: The distribution of health workers in health facility across LGA in Lagos State depend on Ownership type, Facility level of care, and category of the facility. 展开更多
关键词 healthcare Facilities human Resources for health healthcare Delivery Lagos state sDGs on health Multiple Response Analysis
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Spatiotemporal variations of ozone exposure and its risks to vegetation and human health in Cyprus:an analysis across a gradient of altitudes
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作者 Stefanos Agathokleous Costas JSaitanis +3 位作者 Chrysanthos Savvides Pierre Sicard Evgenios Agathokleous Alessandra De Marco 《Journal of Forestry Research》 SCIE CAS CSCD 2023年第3期579-594,共16页
Ground-level ozone(O_(3)) aff ects vegetation and threatens environmental health when levels exceed critical values,above which adverse eff ects are expected.Cyprus is expected to be a hotspot for O_(3)concentrations ... Ground-level ozone(O_(3)) aff ects vegetation and threatens environmental health when levels exceed critical values,above which adverse eff ects are expected.Cyprus is expected to be a hotspot for O_(3)concentrations due to its unique position in the eastern Mediterranean,receiving air masses from Europe,African,and Asian continents,and experiencing a warm Mediterranean climate.In Cyprus,the spatiotemporal features of O_(3) are poorly understood and the potential risks for forest health have not been explored.We evaluated O_(3) and nitrogen oxides(NO and NO 2)at four regional background stations at different altitudes over 2014−2016.O_(3) risks to vegetation and human health were estimated by calculating accumulated O_(3)exposure over a threshold of 40 nmol mol^(−1)(AOT40)and cumulative exposure to mixing ratios above 35 nmol mol^(−1)(SOMO35)indices.The data reveal that mean O_(3)concentrations follow a seasonal pattern,with higher levels in spring(51.8 nmol mol^(−1))and summer(53.2 nmol mol^(−1))and lower levels in autumn(46.9 nmol mol^(−1))and winter(43.3 nmol mol^(−1)).The highest mean O_(3)exposure(59.5 nmol mol^(−1)) in summer occurred at the high elevation station Mt.Troodos(1819 m a.s.l.).Increasing(decreasing)altitudinal gradients were found for O_(3)(NO x),driven by summer–winter diff erences.The diurnal patterns of O_(3) showed little variation.Only at the lowest altitude O_(3) displayed a typical O_(3) diurnal pattern,with hourly diff erences smaller than 15 nmol mol^(−1).Accumulated O_(3) exposures at all stations and in all years exceeded the European Union’s limits for the protection of vegetation,with average values of 3-month(limit:3000 nmol mol^(−1)h)and 6-month(limit:5000 nmol mol^(−1)h)AOT40 for crops and forests of 16,564 and 31,836 nmol mol^(−1)h,respectively.O_(3) exposures were considerably high for human health,with an average SOMO35 value of 7270 nmol mol^(−1) days across stations and years.The results indicate that O_(3) is a major environmental and public health issue in Cyprus,and policies must be adopted to mitigate O_(3) precursor emissions at local and regional scales. 展开更多
关键词 Air pollution Ozone risk assessment Exposure metrics VEGETATION human health
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A review of physicochemical and biological contaminants in drinking water and their impacts on human health
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作者 Ahsan Shah Arun Arjunan +1 位作者 Ahmad Baroutaji Julia Zakharova 《Water Science and Engineering》 EI CAS CSCD 2023年第4期333-344,共12页
Clean drinking water is one of the United Nations Sustainable Development Goals.Despite significant progress in the water purification technology,many regions still lack access to clean water.This paper provides a rev... Clean drinking water is one of the United Nations Sustainable Development Goals.Despite significant progress in the water purification technology,many regions still lack access to clean water.This paper provides a review of selected water contaminants and their impacts on human health.The World Health Organization(WHO)guidelines and regional standards for key contaminants were used to characterise water quality in the European Union and UK.The concept of safe drinking water was explained based on the non-observed adverse effect level,threshold concentrations for toxic chemicals,and their total daily intake.Various techniques for monitoring water contaminants and the drinking water standards from five different countries,including the UK,USA,Canada,Pakistan and India,were compared to WHO recommended guidelines.The literature on actual water quality in these regions and its potential health impacts was also discussed.Finally,the role of public water suppliers in identifying and monitoring drinking water contaminants in selected developed countries was presented as a potential guideline for developing countries.This review emphasised the need for a comprehensive understanding of water quality and its impacts on human health to ensure access to clean drinking water worldwide. 展开更多
关键词 Drinking water contaminants Physicochemical contaminants Biological contaminants human health risks Waterborne diseases Water quality Public health concerns Water treatment
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Focusing on individualized nutrition within the algorithmic diet: an in-depth look at recent advances in nutritional science, microbial diversity studies, and human health
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作者 Reyed M Reyed 《Food and Health》 2023年第1期22-50,共29页
A healthy balanced diet and a healthy lifestyle are very closely linked.Whichever the biological link is,it is overwhelming to understand.Modifications in how food is served,divided up,and supervised,such as the intro... A healthy balanced diet and a healthy lifestyle are very closely linked.Whichever the biological link is,it is overwhelming to understand.Modifications in how food is served,divided up,and supervised,such as the introduction of nutritional hygiene standards,food handling practices,and the entry of macro and micronutrients,have had a big impact on human health in the last few decades.Growing evidence indicates that our gut microbiota may affect our health in ways that are at least in part influenced by our diet and the ingredients used in the preparation of our food and drinks,as well as other factors.As a new problem,this one is getting a lot of attention,but it would be hard to figure out how the gut microbiota and nutrition molecules work together and how they work in certain situations.Genetic analysis,metagenomic characterization,configuration analysis of foodstuffs,and the shift to digital health information have provided massive amounts of data that might be useful in tackling this problem.Machine learning and deep learning methods will be employed extensively as part of this research in order to blend complicated data frames and extract crucial information that will be capable of exposing and grasping the incredibly delicate links that prevail between diet,gut microbiome,and overall wellbeing.Nutrition,well-being,and gut microorganisms are a few subjects covered in this field.It takes into account not only databases and high-speed technology,but also virtual machine problem-solving skills,intangible assets,and laws.This is how it works:Computer vision,data mining,and analytics are all discussed extensively in this study piece.We also point out limitations in existing methodologies and new situations that discovered in the context of current scientific knowledge in the decades to come.We also provide background on"bioinformatics"algorithms;recent developments may seem to herald a revolution in clinical research,pushing traditional techniques to the sidelines.Furthermore,their true potential rests in their ability to work in conjunction with,rather than as a substitute for,traditional research hypotheses and procedures.When new metadata propositions are made by focusing on easily understandable frameworks,they will always need to be rigorously validated and brought into question.Because of the huge datasets available,assumption analysis may be used to complement rather than a substitute for more conventional concept-driven scientific investigation.It is only by employing all of us that we will all increase the quality of evidence-based practice. 展开更多
关键词 nutritional databank nutritional human gut microbiota MICROBIOME big data algorithms public health dietary programming application
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