The aims of this study were （a） to determine the prevalence of subjects with semen hyperviscosity （SHV） in a large population of male partners of subfertile couples; （b） to identify any correlation between SHV a...The aims of this study were （a） to determine the prevalence of subjects with semen hyperviscosity （SHV） in a large population of male partners of subfertile couples; （b） to identify any correlation between SHV and infections or inflammation of the genital tract; （c） to assess the effects of therapeutic approaches for treating SHV; and （d） to assess sperm kinetic parameters after successful treatment of SHV. A retrospective study of 1 833 male partners of subfertile couples was conducted. Next, clinical, seminal, bacteriological and ultrasound studies involving 52 subjects suffering from SHV were performed, and the SHV was classified as being mild （length of thread 〉 2 cm and ≤4 cm）, moderate （〉 4 cm and ≤ 6 cm） or severe （〉 6 cm）. The prevalence of SHV was observed in 26.2% （480） of the subjects, with 13.2% suffering from mild, 6.6% from moderate and 6.4% from severe SHV. Treatment was completely successful in only 27 subjects （52.0%）, primarily in those who had mild basal SHV with a positive semen culture. In these subjects, progressive motility percentage, straight line velocity and linearity were significantly higher than pre-treatment levels. SHV is often found in subjects with subfertility. Pathogenesis was strictly related to infective/inflammatory factors in only 48.0% of cases; therefore, it is possible that biochemical, enzymatic or genetic factors have a role in this condition.展开更多
That 140 patients with blood hyperviscosity syndrome and blood stasis were treated with "Kangshuanling"proved the traditional medicine effective in decreasing cumulative scores of BHS, BS, concentration, vis...That 140 patients with blood hyperviscosity syndrome and blood stasis were treated with "Kangshuanling"proved the traditional medicine effective in decreasing cumulative scores of BHS, BS, concentration, viscosity and coagulation, and lowering stress and increasing cerebral flow as well (p<0. 05-0. 001). The project is supported by the National Natural Science Foundation of China. "Kangshuanling",in western term means positive action against thrombus and improving blood circulation, and in the theory of traditional medicine, it means invigorating "qi" by promoting blood circulation and removing blood stasis, namely making the stagnant blood flowing and bringing blood circulation to normality. Blood stasis consists of four hemorheological abnormalities, namely, concentration, high viscosity, high aggregation and high coagulation of blood. Those are diagnosed as BHS. There is also a positive correlation (r=0. 8307-0.8869, p<0. 001)between BHS and BS preand post treatment. It suggests that BHS may be an entity in BS.展开更多
Hemorheological changes of 45 cases with malignant tumors are investigated and compared with 709 healthy persons. Results show that blood viscosity, plasma viscosity, fibrinogen, erythrocyte deformability index, eryth...Hemorheological changes of 45 cases with malignant tumors are investigated and compared with 709 healthy persons. Results show that blood viscosity, plasma viscosity, fibrinogen, erythrocyte deformability index, erythrocyte sedimentation rate(ESR), ESR -K and erythrocyte electrophoresis time are obviously increased, while hematocrit is significantly lower than that of control groups. This indicates that patients with malignant tumors have hyperviscosity syndromes.展开更多
Multiple myeloma(MM)is a heterogeneous disease of the hematological system,characterized by different subtypes and different prognosis.Age,tumor burden,biological characteristics and treatment response can affect the ...Multiple myeloma(MM)is a heterogeneous disease of the hematological system,characterized by different subtypes and different prognosis.Age,tumor burden,biological characteristics and treatment response can affect the prognosis.MM cells accumulate in bone marrow and produce abnormal immunoglobulin.Abnormal immunoglobulin does not participate in immune response and inhibits adaptive immune system is the most significant pathophysiological characteristics of MM.Hyperviscosity,amyloidosis,infection and kidney injury are the important complications of MM.This paper analyzes the traditional Chinese medicine(TCM)understanding of these important complications,and summarizes the commonly used clinical Chinese medicine,in order to provide important basis for the TCM treatment of multiple myeloma.展开更多
文摘The aims of this study were （a） to determine the prevalence of subjects with semen hyperviscosity （SHV） in a large population of male partners of subfertile couples; （b） to identify any correlation between SHV and infections or inflammation of the genital tract; （c） to assess the effects of therapeutic approaches for treating SHV; and （d） to assess sperm kinetic parameters after successful treatment of SHV. A retrospective study of 1 833 male partners of subfertile couples was conducted. Next, clinical, seminal, bacteriological and ultrasound studies involving 52 subjects suffering from SHV were performed, and the SHV was classified as being mild （length of thread 〉 2 cm and ≤4 cm）, moderate （〉 4 cm and ≤ 6 cm） or severe （〉 6 cm）. The prevalence of SHV was observed in 26.2% （480） of the subjects, with 13.2% suffering from mild, 6.6% from moderate and 6.4% from severe SHV. Treatment was completely successful in only 27 subjects （52.0%）, primarily in those who had mild basal SHV with a positive semen culture. In these subjects, progressive motility percentage, straight line velocity and linearity were significantly higher than pre-treatment levels. SHV is often found in subjects with subfertility. Pathogenesis was strictly related to infective/inflammatory factors in only 48.0% of cases; therefore, it is possible that biochemical, enzymatic or genetic factors have a role in this condition.
文摘That 140 patients with blood hyperviscosity syndrome and blood stasis were treated with "Kangshuanling"proved the traditional medicine effective in decreasing cumulative scores of BHS, BS, concentration, viscosity and coagulation, and lowering stress and increasing cerebral flow as well (p<0. 05-0. 001). The project is supported by the National Natural Science Foundation of China. "Kangshuanling",in western term means positive action against thrombus and improving blood circulation, and in the theory of traditional medicine, it means invigorating "qi" by promoting blood circulation and removing blood stasis, namely making the stagnant blood flowing and bringing blood circulation to normality. Blood stasis consists of four hemorheological abnormalities, namely, concentration, high viscosity, high aggregation and high coagulation of blood. Those are diagnosed as BHS. There is also a positive correlation (r=0. 8307-0.8869, p<0. 001)between BHS and BS preand post treatment. It suggests that BHS may be an entity in BS.
文摘Hemorheological changes of 45 cases with malignant tumors are investigated and compared with 709 healthy persons. Results show that blood viscosity, plasma viscosity, fibrinogen, erythrocyte deformability index, erythrocyte sedimentation rate(ESR), ESR -K and erythrocyte electrophoresis time are obviously increased, while hematocrit is significantly lower than that of control groups. This indicates that patients with malignant tumors have hyperviscosity syndromes.
文摘Multiple myeloma(MM)is a heterogeneous disease of the hematological system,characterized by different subtypes and different prognosis.Age,tumor burden,biological characteristics and treatment response can affect the prognosis.MM cells accumulate in bone marrow and produce abnormal immunoglobulin.Abnormal immunoglobulin does not participate in immune response and inhibits adaptive immune system is the most significant pathophysiological characteristics of MM.Hyperviscosity,amyloidosis,infection and kidney injury are the important complications of MM.This paper analyzes the traditional Chinese medicine(TCM)understanding of these important complications,and summarizes the commonly used clinical Chinese medicine,in order to provide important basis for the TCM treatment of multiple myeloma.
