Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)tec...Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)technique has been popularly utilized to study SZ.However,it is still a great challenge to reveal the essential information contained in the MRI data.In this paper,we proposed a biomarker selection approach based on the multiple hypothesis testing techniques to explore the difference between SZ and healthy controls by using both functional and structural MRI data,in which biomarkers represent both abnormal brain functional connectivity and abnormal brain regions.By implementing the biomarker selection approach,six abnormal brain regions and twenty-three abnormal functional connectivity in the brains of SZ are explored.It is discovered that compared with healthy controls,the significantly reduced gray matter volumes are mainly distributed in the limbic lobe and the basal ganglia,and the significantly increased gray matter volumes are distributed in the frontal gyrus.Meanwhile,it is revealed that the significantly strengthened connections are those between the middle frontal gyrus and the superior occipital gyrus,the superior occipital gyrus and the middle occipital gyrus as well as the middle occipital gyrus and the fusiform gyrus,and the rest connections are significantly weakened.展开更多
The radiative hypothesis has been revisited showing other characteristics, produced by the protons used as dyes in total disagree with the ones of the Body Image that appears on the Shroud of Turin. Our investigations...The radiative hypothesis has been revisited showing other characteristics, produced by the protons used as dyes in total disagree with the ones of the Body Image that appears on the Shroud of Turin. Our investigations highlight that for the protons to reach 3.7 cm in air, the distance that measures the range of discoloration effects, must be emitted with an energy of about 1.5 MeV using Wilson and Brobeck’s empirical formula and 1.35 MeV using Bethe’s. This last formula provides a result closer to reality. Bethe shows that the penetration depth is greater than that calculated empirically. Such a value of proton energy (1.35 MeV) makes it possible to satisfy the discoloration effects range for the Shroud but it is incompatible with a depth of penetration in linen that is only 200 nm. Moreover, using the same subatomic particles, we obtained on the colored linen a distribution of energy represented by regression but not linear. Thus, also the possible I(z) correlation, between color intensity and body-sheet distance, which should be due to the oxidizing action of protons, does not agree with that extracted from the Shroud of Turin.展开更多
After almost fifteen years, we remind our fellow scientists of the Stochastic process, a natural mechanism for obtaining the Shroud Body Image. The above process is considered the only source of energy present in an a...After almost fifteen years, we remind our fellow scientists of the Stochastic process, a natural mechanism for obtaining the Shroud Body Image. The above process is considered the only source of energy present in an ancient tomb: the thermal one emitted by the corpse of Jesus Christ. It, for all corpses, is notoriously so weak that the only process that could be triggered is the Stochastic one. However, the best-known expert scientists in the Shroud of Turin investigation did not take this model into account, even if it guaranteed a latent image, typical of the Stochastic process, and a fibrils distribution as appears on the Shroud surface. The above scientists and many others had already chosen the Radiative hypothesis, which is based on the emission of radiation (Ultraviolet) and nuclear particles (Protons and Neutrons) by the corpse of Jesus Christ. These emissions are impossible;conversely, if they were true, we would have to talk about miracles. Today, after four decades, it would be appropriate to accept that the Radiative hypothesis (which in the Turin Shroud case becomes a miraculous hypothesis) cannot be in line with both Physics and Theology. We think that we should all be more fiscal when we judge our work.展开更多
基金This work was supported by NSFC(No.11471006 and No.81601456),Science and Technology Innovation Plan of Xi’an(No.2019421315KYPT004JC006)and the HPC Platform,Xi’an Jiaotong University.
文摘Schizophrenia(SZ)is one of the most common mental diseases.Its main characteristics are abnormal social behavior and inability to correctly understand real things.In recent years,the magnetic resonance imaging(MRI)technique has been popularly utilized to study SZ.However,it is still a great challenge to reveal the essential information contained in the MRI data.In this paper,we proposed a biomarker selection approach based on the multiple hypothesis testing techniques to explore the difference between SZ and healthy controls by using both functional and structural MRI data,in which biomarkers represent both abnormal brain functional connectivity and abnormal brain regions.By implementing the biomarker selection approach,six abnormal brain regions and twenty-three abnormal functional connectivity in the brains of SZ are explored.It is discovered that compared with healthy controls,the significantly reduced gray matter volumes are mainly distributed in the limbic lobe and the basal ganglia,and the significantly increased gray matter volumes are distributed in the frontal gyrus.Meanwhile,it is revealed that the significantly strengthened connections are those between the middle frontal gyrus and the superior occipital gyrus,the superior occipital gyrus and the middle occipital gyrus as well as the middle occipital gyrus and the fusiform gyrus,and the rest connections are significantly weakened.
文摘The radiative hypothesis has been revisited showing other characteristics, produced by the protons used as dyes in total disagree with the ones of the Body Image that appears on the Shroud of Turin. Our investigations highlight that for the protons to reach 3.7 cm in air, the distance that measures the range of discoloration effects, must be emitted with an energy of about 1.5 MeV using Wilson and Brobeck’s empirical formula and 1.35 MeV using Bethe’s. This last formula provides a result closer to reality. Bethe shows that the penetration depth is greater than that calculated empirically. Such a value of proton energy (1.35 MeV) makes it possible to satisfy the discoloration effects range for the Shroud but it is incompatible with a depth of penetration in linen that is only 200 nm. Moreover, using the same subatomic particles, we obtained on the colored linen a distribution of energy represented by regression but not linear. Thus, also the possible I(z) correlation, between color intensity and body-sheet distance, which should be due to the oxidizing action of protons, does not agree with that extracted from the Shroud of Turin.
文摘After almost fifteen years, we remind our fellow scientists of the Stochastic process, a natural mechanism for obtaining the Shroud Body Image. The above process is considered the only source of energy present in an ancient tomb: the thermal one emitted by the corpse of Jesus Christ. It, for all corpses, is notoriously so weak that the only process that could be triggered is the Stochastic one. However, the best-known expert scientists in the Shroud of Turin investigation did not take this model into account, even if it guaranteed a latent image, typical of the Stochastic process, and a fibrils distribution as appears on the Shroud surface. The above scientists and many others had already chosen the Radiative hypothesis, which is based on the emission of radiation (Ultraviolet) and nuclear particles (Protons and Neutrons) by the corpse of Jesus Christ. These emissions are impossible;conversely, if they were true, we would have to talk about miracles. Today, after four decades, it would be appropriate to accept that the Radiative hypothesis (which in the Turin Shroud case becomes a miraculous hypothesis) cannot be in line with both Physics and Theology. We think that we should all be more fiscal when we judge our work.
