CMOS image sensors produced by the existing CMOS manufacturing process usually have difficulty achieving complete charge transfer owing to the introduction of potential barriers or Si/SiO_(2)interface state traps in t...CMOS image sensors produced by the existing CMOS manufacturing process usually have difficulty achieving complete charge transfer owing to the introduction of potential barriers or Si/SiO_(2)interface state traps in the charge transfer path,which reduces the charge transfer efficiency and image quality.Until now,scholars have only considered mechanisms that limit charge transfer from the perspectives of potential barriers and spill back effect under high illumination condition.However,the existing models have thus far ignored the charge transfer limitation due to Si/SiO_(2)interface state traps in the transfer gate channel,particularly under low illumination.Therefore,this paper proposes,for the first time,an analytical model for quantifying the incomplete charge transfer caused by Si/SiO_(2)interface state traps in the transfer gate channel under low illumination.This model can predict the variation rules of the number of untransferred charges and charge transfer efficiency when the trap energy level follows Gaussian distribution,exponential distribution and measured distribution.The model was verified with technology computer-aided design simulations,and the results showed that the simulation results exhibit the consistency with the proposed model.展开更多
The adsorption and electronic properties of isolated cobalt phthalocyanine （CoPc） molecule on an ultrathin layer of NaC1 have been investigated. High-resolution STM images give a detailed picture of the lowest unocc...The adsorption and electronic properties of isolated cobalt phthalocyanine （CoPc） molecule on an ultrathin layer of NaC1 have been investigated. High-resolution STM images give a detailed picture of the lowest unoccupied molecular orbital （LUMO） of an isolated CoPc. It is shown that the NaC1 ultrathin layer efficiently decouples the interaction of the molecules from the underneath metal substrate, which makes it an ideal substrate for studying the properties of single molecules. Moreover, strong dependence of the appearance of the molecules on the sample bias in the region of relatively high bias （〉 3.1 V） is ascribed to the image potential states （IPSs） of NaCI/Cu（100）, which may provide us with a possible method to fabricate quantum storage devices.展开更多
It is often necessary to recognize human mouth-states for detecting the number of audio sources and improving the speech recognition capability of an intelligent robot auditory system. A human mouth-state recognition ...It is often necessary to recognize human mouth-states for detecting the number of audio sources and improving the speech recognition capability of an intelligent robot auditory system. A human mouth-state recognition method based on image warping and sparse representation( SR) combined with homotopy is proposed.Using properly warped training mouth-state images as atoms of the overcomplete dictionary overcomes the impact of the diversity of the mouths' scales,shapes and positions so that further improvement of the robustness can be achieved and the requirement for a large number of training samples can be relieved. The homotopy method is employed to compute the expansion coefficients effectively,i. e.,for sparse coding. The orthogonal matching pursuit( OMP) is also tested and compared with the homototy method. Experimental results and comparisons with the state-of-the-art methods have proved the effectiveness of the proposed approach.展开更多
Indoor Wi-Fi localization of mobile devices plays a more and more important role along with the rapid growth of location-based services and Wi-Fi mobile devices.In this paper,a new method of constructing the channel s...Indoor Wi-Fi localization of mobile devices plays a more and more important role along with the rapid growth of location-based services and Wi-Fi mobile devices.In this paper,a new method of constructing the channel state information(CSI)image is proposed to improve the localization accuracy.Compared with previous methods of constructing the CSI image,the new kind of CSI image proposed is able to contain more channel information such as the angle of arrival(AoA),the time of arrival(TOA)and the amplitude.We construct three gray images by using phase differences of different antennas and amplitudes of different subcarriers of one antenna,and then merge them to form one RGB image.The localization method has off-line stage and on-line stage.In the off-line stage,the composed three-channel RGB images at training locations are used to train a convolutional neural network(CNN)which has been proved to be efficient in image recognition.In the on-line stage,images at test locations are fed to the well-trained CNN model and the localization result is the weighted mean value with highest output values.The performance of the proposed method is verified with extensive experiments in the representative indoor environment.展开更多
The main symptom of patients with Alzheimer’s disease is cognitive dysfunction. Alzheimer’s disease is mainly diagnosed based on changes in brain structure. Functional connectivity reflects the synchrony of function...The main symptom of patients with Alzheimer’s disease is cognitive dysfunction. Alzheimer’s disease is mainly diagnosed based on changes in brain structure. Functional connectivity reflects the synchrony of functional activities between non-adjacent brain regions, and changes in functional connectivity appear earlier than those in brain structure. In this study, we detected resting-state functional connectivity changes in patients with Alzheimer’s disease to provide reference evidence for disease prediction. Functional magnetic resonance imaging data from patients with Alzheimer’s disease were used to show whether particular white and gray matter areas had certain functional connectivity patterns and if these patterns changed with disease severity. In nine white and corresponding gray matter regions, correlations of normal cognition, early mild cognitive impairment, and late mild cognitive impairment with blood oxygen level-dependent signal time series were detected. Average correlation coefficient analysis indicated functional connectivity patterns between white and gray matter in the resting state of patients with Alzheimer’s disease. Functional connectivity pattern variation correlated with disease severity, with some regions having relatively strong or weak correlations. We found that the correlation coefficients of five regions were 0.3–0.5 in patients with normal cognition and 0–0.2 in those developing Alzheimer’s disease. Moreover, in the other four regions, the range increased to 0.45–0.7 with increasing cognitive impairment. In some white and gray matter areas, there were specific connectivity patterns. Changes in regional white and gray matter connectivity patterns may be used to predict Alzheimer’s disease;however, detailed information on specific connectivity patterns is needed. All study data were obtained from the Alzheimer’s Disease Neuroimaging Initiative Library of the Image and Data Archive Database.展开更多
Dielectric metasurfaces play an increasingly important role in enhancing optical nonlinear generations owing to their ability to support strong light-matter interactions based on Mie-type multipolar resonances.Compare...Dielectric metasurfaces play an increasingly important role in enhancing optical nonlinear generations owing to their ability to support strong light-matter interactions based on Mie-type multipolar resonances.Compared to metasurfaces composed of the periodic arrangement of nanoparticles,inverse,so-called,membrane metasurfaces offer unique possibilities for supporting multipolar resonances,while maintaining small unit cell size,large mode volume and high field enhancement for enhancing nonlinear frequency conversion.Here,we theoretically and experimentally investigate the formation of bound states in the continuum(BICs)from silicon dimer-hole membrane metasurfaces.We demonstrate that our BIC-formed resonance features a strong and tailorable electric near-field confinement inside the silicon membrane films.Furthermore,we show that by tuning the gap between the holes,one can open a leaky channel to transform these regular BICs into quasi-BICs,which can be excited directly under normal plane wave incidence.To prove the capabilities of such metasurfaces,we demonstrate the conversion of an infrared image to the visible range,based on the Third-harmonic generation(THG)process with the resonant membrane metasurfaces.Our results suggest a new paradigm for realising efficient nonlinear photonics metadevices and hold promise for extending the applications of nonlinear structuring surfaces to new types of all-optical near-infrared imaging technologies.展开更多
Based on a large amount of dissection at welded interface and quantitative microscopic examination of welded rate, the suitable limit grey scale value was determined, and the welded rate of superplastic solid state w...Based on a large amount of dissection at welded interface and quantitative microscopic examination of welded rate, the suitable limit grey scale value was determined, and the welded rate of superplastic solid state welding interface of heterogeneous steel was systematically studied by means of self made ultrasonic C scanning imaging inspection system. The experimental results show: the welded state of superplastic solid state welding interface of heterogeneous steel can be conducted to be more accurately, reliably and quickly inspected by means of this system, and the ultrasonic testing results are good consistent with actual examination results of the interface defective distribution. Within the extent of the suitble welded rate,the welded rate in 40Cr/T10A superplastic welding process tested by this system is linear with its tensile strength of joint.展开更多
BACKGROUND Diabetes is a common chronic disease.Given the increasing incidence of diabetes,more individuals are affected by diabetic optic neuropathy(DON),which results in decreased vision.Whether DON leads to abnorma...BACKGROUND Diabetes is a common chronic disease.Given the increasing incidence of diabetes,more individuals are affected by diabetic optic neuropathy(DON),which results in decreased vision.Whether DON leads to abnormalities of other visual systems,including the eye,the visual cortex,and other brain regions,remains unknown.AIM To investigate the local characteristics of spontaneous brain activity using regional homogeneity(ReHo)in patients with DON.METHODS We matched 22 patients with DON with 22 healthy controls(HCs).All subjects underwent resting-state functional magnetic resonance imaging.The ReHo technique was used to record spontaneous changes in brain activity.Receiver operating characteristic(ROC)curves were applied to differentiate between ReHo values for patients with DON and HCs.We also assessed the correlation between Hospital Anxiety and Depression Scale scores and ReHo values in DON patients using Pearson correlation analysis.RESULTS ReHo values of the right middle frontal gyrus(RMFG),left anterior cingulate(LAC),and superior frontal gyrus(SFG)/left frontal superior orbital gyrus(LFSO)were significantly lower in DON patients compared to HCs.Among these,the greatest difference was observed in the RMFG.The result of the ROC curves suggest that ReHo values in altered brain regions may help diagnose DON,and the RMFG and LAC ReHo values are more clinically relevant than SFG/LFSO.We also found that anxiety and depression scores of the DON group were extremely negatively correlated with the LAC ReHo values(r=-0.9336,P<0.0001 and r=-0.8453,P<0.0001,respectively).CONCLUSION Three different brain regions show ReHo changes in DON patients,and these changes could serve as diagnostic and/or prognostic biomarkers to further guide the prevention and treatment of DON patients.展开更多
The thermal-based imaging technique has recently attracted the attention of researchers who are interested in the recognition of human affects dueto its ability to measure the facial transient temperature, which is co...The thermal-based imaging technique has recently attracted the attention of researchers who are interested in the recognition of human affects dueto its ability to measure the facial transient temperature, which is correlated withhuman affects and robustness against illumination changes. Therefore, studieshave increasingly used the thermal imaging as a potential and supplemental solution to overcome the challenges of visual (RGB) imaging, such as the variation oflight conditions and revealing original human affect. Moreover, the thermal-basedimaging has shown promising results in the detection of psychophysiological signals, such as pulse rate and respiration rate in a contactless and noninvasive way.This paper presents a brief review on human affects and focuses on the advantages and challenges of the thermal imaging technique. In addition, this paper discusses the stages of thermal-based human affective state recognition, such asdataset type, preprocessing stage, region of interest (ROI), feature descriptors,and classification approaches with a brief performance analysis based on a number of works in the literature. This analysis could help beginners in the thermalimaging and affective recognition domain to explore numerous approaches usedby researchers to construct an affective state system based on thermal imaging.展开更多
Although some short-term follow-up studies have found that individuals recovering from coronavirus disease 2019(COVID-19)exhibit anxiety,depression,and altered brain microstructure,their long-term physical problems,ne...Although some short-term follow-up studies have found that individuals recovering from coronavirus disease 2019(COVID-19)exhibit anxiety,depression,and altered brain microstructure,their long-term physical problems,neuropsychiatric sequelae,and changes in brain function remain unknown.This observational cohort study collected 1-year follow-up data from 22 patients who had been hospitalized with COVID-19(8 males and 11 females,aged 54.2±8.7 years).Fatigue and myalgia were persistent symptoms at the 1-year follow-up.The resting state functional magnetic resonance imaging revealed that compared with 29 healthy controls(7 males and 18 females,aged 50.5±11.6 years),COVID-19 survivors had greatly increased amplitude of low-frequency fluctuation(ALFF)values in the left precentral gyrus,middle frontal gyrus,inferior frontal gyrus of operculum,inferior frontal gyrus of triangle,insula,hippocampus,parahippocampal gyrus,fusiform gyrus,postcentral gyrus,inferior parietal angular gyrus,supramarginal gyrus,angular gyrus,thalamus,middle temporal gyrus,inferior temporal gyrus,caudate,and putamen.ALFF values in the left caudate of the COVID-19 survivors were positively correlated with their Athens Insomnia Scale scores,and those in the left precentral gyrus were positively correlated with neutrophil count during hospitalization.The long-term follow-up results suggest that the ALFF in brain regions related to mood and sleep regulation were altered in COVID-19 survivors.This can help us understand the neurobiological mechanisms of COVID-19-related neuropsychiatric sequelae.This study was approved by the Ethics Committee of the Second Xiangya Hospital of Central South University(approval No.2020 S004)on March 19,2020.展开更多
基金supported by the National Natural Science Foundation of China(62171172).
文摘CMOS image sensors produced by the existing CMOS manufacturing process usually have difficulty achieving complete charge transfer owing to the introduction of potential barriers or Si/SiO_(2)interface state traps in the charge transfer path,which reduces the charge transfer efficiency and image quality.Until now,scholars have only considered mechanisms that limit charge transfer from the perspectives of potential barriers and spill back effect under high illumination condition.However,the existing models have thus far ignored the charge transfer limitation due to Si/SiO_(2)interface state traps in the transfer gate channel,particularly under low illumination.Therefore,this paper proposes,for the first time,an analytical model for quantifying the incomplete charge transfer caused by Si/SiO_(2)interface state traps in the transfer gate channel under low illumination.This model can predict the variation rules of the number of untransferred charges and charge transfer efficiency when the trap energy level follows Gaussian distribution,exponential distribution and measured distribution.The model was verified with technology computer-aided design simulations,and the results showed that the simulation results exhibit the consistency with the proposed model.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.21203239 and 21311120059)RFBR(Grant No.13-02-91180)
文摘The adsorption and electronic properties of isolated cobalt phthalocyanine （CoPc） molecule on an ultrathin layer of NaC1 have been investigated. High-resolution STM images give a detailed picture of the lowest unoccupied molecular orbital （LUMO） of an isolated CoPc. It is shown that the NaC1 ultrathin layer efficiently decouples the interaction of the molecules from the underneath metal substrate, which makes it an ideal substrate for studying the properties of single molecules. Moreover, strong dependence of the appearance of the molecules on the sample bias in the region of relatively high bias （〉 3.1 V） is ascribed to the image potential states （IPSs） of NaCI/Cu（100）, which may provide us with a possible method to fabricate quantum storage devices.
基金National Natural Science Foundation of China(No.61210306074)Natural Science Foundation of Jiangxi Province,China(No.2012BAB201025)the Scientific Program of Jiangxi Provincial Education Department,China(Nos.GJJ14583,GJJ13008)
文摘It is often necessary to recognize human mouth-states for detecting the number of audio sources and improving the speech recognition capability of an intelligent robot auditory system. A human mouth-state recognition method based on image warping and sparse representation( SR) combined with homotopy is proposed.Using properly warped training mouth-state images as atoms of the overcomplete dictionary overcomes the impact of the diversity of the mouths' scales,shapes and positions so that further improvement of the robustness can be achieved and the requirement for a large number of training samples can be relieved. The homotopy method is employed to compute the expansion coefficients effectively,i. e.,for sparse coding. The orthogonal matching pursuit( OMP) is also tested and compared with the homototy method. Experimental results and comparisons with the state-of-the-art methods have proved the effectiveness of the proposed approach.
基金supported by the National Natural Science Foundation of China (No.61631013)National Key Basic Research Program of China (973 Program) (No. 2013CB329002)National Major Project (NO. 2018ZX03001006003)
文摘Indoor Wi-Fi localization of mobile devices plays a more and more important role along with the rapid growth of location-based services and Wi-Fi mobile devices.In this paper,a new method of constructing the channel state information(CSI)image is proposed to improve the localization accuracy.Compared with previous methods of constructing the CSI image,the new kind of CSI image proposed is able to contain more channel information such as the angle of arrival(AoA),the time of arrival(TOA)and the amplitude.We construct three gray images by using phase differences of different antennas and amplitudes of different subcarriers of one antenna,and then merge them to form one RGB image.The localization method has off-line stage and on-line stage.In the off-line stage,the composed three-channel RGB images at training locations are used to train a convolutional neural network(CNN)which has been proved to be efficient in image recognition.In the on-line stage,images at test locations are fed to the well-trained CNN model and the localization result is the weighted mean value with highest output values.The performance of the proposed method is verified with extensive experiments in the representative indoor environment.
基金supported by the National Natural Science Foundation of China,No.61401308,61572063(both to XHW)the Natural Science Foundation of Beijing of China,No.L172055(to XHW)+3 种基金the Beijing Municipal Science&Technology Commission Research Fund of China,No.Z171100000417004(to XHW)the China Postdoctoral Fund,No.2018M631755(to XHW)the Special Fund for Improving Comprehensive Strength of Hebei University in the Midwest of China,No.801260201011(to XHW)the High-Level Talent Funding Project—Selective Post-doctoral Research Project Fund of Hebei Province of China,No.B2018003002(to XHW)
文摘The main symptom of patients with Alzheimer’s disease is cognitive dysfunction. Alzheimer’s disease is mainly diagnosed based on changes in brain structure. Functional connectivity reflects the synchrony of functional activities between non-adjacent brain regions, and changes in functional connectivity appear earlier than those in brain structure. In this study, we detected resting-state functional connectivity changes in patients with Alzheimer’s disease to provide reference evidence for disease prediction. Functional magnetic resonance imaging data from patients with Alzheimer’s disease were used to show whether particular white and gray matter areas had certain functional connectivity patterns and if these patterns changed with disease severity. In nine white and corresponding gray matter regions, correlations of normal cognition, early mild cognitive impairment, and late mild cognitive impairment with blood oxygen level-dependent signal time series were detected. Average correlation coefficient analysis indicated functional connectivity patterns between white and gray matter in the resting state of patients with Alzheimer’s disease. Functional connectivity pattern variation correlated with disease severity, with some regions having relatively strong or weak correlations. We found that the correlation coefficients of five regions were 0.3–0.5 in patients with normal cognition and 0–0.2 in those developing Alzheimer’s disease. Moreover, in the other four regions, the range increased to 0.45–0.7 with increasing cognitive impairment. In some white and gray matter areas, there were specific connectivity patterns. Changes in regional white and gray matter connectivity patterns may be used to predict Alzheimer’s disease;however, detailed information on specific connectivity patterns is needed. All study data were obtained from the Alzheimer’s Disease Neuroimaging Initiative Library of the Image and Data Archive Database.
基金the support from the Royal Society scholarshipsupport from the UK Research and Innovation Future Leaders Fellowship (MR/T040513/1).
文摘Dielectric metasurfaces play an increasingly important role in enhancing optical nonlinear generations owing to their ability to support strong light-matter interactions based on Mie-type multipolar resonances.Compared to metasurfaces composed of the periodic arrangement of nanoparticles,inverse,so-called,membrane metasurfaces offer unique possibilities for supporting multipolar resonances,while maintaining small unit cell size,large mode volume and high field enhancement for enhancing nonlinear frequency conversion.Here,we theoretically and experimentally investigate the formation of bound states in the continuum(BICs)from silicon dimer-hole membrane metasurfaces.We demonstrate that our BIC-formed resonance features a strong and tailorable electric near-field confinement inside the silicon membrane films.Furthermore,we show that by tuning the gap between the holes,one can open a leaky channel to transform these regular BICs into quasi-BICs,which can be excited directly under normal plane wave incidence.To prove the capabilities of such metasurfaces,we demonstrate the conversion of an infrared image to the visible range,based on the Third-harmonic generation(THG)process with the resonant membrane metasurfaces.Our results suggest a new paradigm for realising efficient nonlinear photonics metadevices and hold promise for extending the applications of nonlinear structuring surfaces to new types of all-optical near-infrared imaging technologies.
基金supported by Henan Natural Science Foundation of China under Grant No:984040900
文摘Based on a large amount of dissection at welded interface and quantitative microscopic examination of welded rate, the suitable limit grey scale value was determined, and the welded rate of superplastic solid state welding interface of heterogeneous steel was systematically studied by means of self made ultrasonic C scanning imaging inspection system. The experimental results show: the welded state of superplastic solid state welding interface of heterogeneous steel can be conducted to be more accurately, reliably and quickly inspected by means of this system, and the ultrasonic testing results are good consistent with actual examination results of the interface defective distribution. Within the extent of the suitble welded rate,the welded rate in 40Cr/T10A superplastic welding process tested by this system is linear with its tensile strength of joint.
基金This work is supported by the National Natural Science Foundation of China(No.22103075,No.21827804,and No.22173089)the National Key R&D Program of China(No.2021YFA0716801andNo.2017YFA0303502).
基金National Natural Science Foundation of China,No.81660158 and No.81400372Natural Science Research Foundation of Jiangxi Province,No.20161ACB21017Medical Science Foundation of Jiangxi Province,No.20181BBG70004 and No.20164017.
文摘BACKGROUND Diabetes is a common chronic disease.Given the increasing incidence of diabetes,more individuals are affected by diabetic optic neuropathy(DON),which results in decreased vision.Whether DON leads to abnormalities of other visual systems,including the eye,the visual cortex,and other brain regions,remains unknown.AIM To investigate the local characteristics of spontaneous brain activity using regional homogeneity(ReHo)in patients with DON.METHODS We matched 22 patients with DON with 22 healthy controls(HCs).All subjects underwent resting-state functional magnetic resonance imaging.The ReHo technique was used to record spontaneous changes in brain activity.Receiver operating characteristic(ROC)curves were applied to differentiate between ReHo values for patients with DON and HCs.We also assessed the correlation between Hospital Anxiety and Depression Scale scores and ReHo values in DON patients using Pearson correlation analysis.RESULTS ReHo values of the right middle frontal gyrus(RMFG),left anterior cingulate(LAC),and superior frontal gyrus(SFG)/left frontal superior orbital gyrus(LFSO)were significantly lower in DON patients compared to HCs.Among these,the greatest difference was observed in the RMFG.The result of the ROC curves suggest that ReHo values in altered brain regions may help diagnose DON,and the RMFG and LAC ReHo values are more clinically relevant than SFG/LFSO.We also found that anxiety and depression scores of the DON group were extremely negatively correlated with the LAC ReHo values(r=-0.9336,P<0.0001 and r=-0.8453,P<0.0001,respectively).CONCLUSION Three different brain regions show ReHo changes in DON patients,and these changes could serve as diagnostic and/or prognostic biomarkers to further guide the prevention and treatment of DON patients.
基金funded by the research university grant by Universiti Sains Malaysia[1001.PKOMP.8014001].
文摘The thermal-based imaging technique has recently attracted the attention of researchers who are interested in the recognition of human affects dueto its ability to measure the facial transient temperature, which is correlated withhuman affects and robustness against illumination changes. Therefore, studieshave increasingly used the thermal imaging as a potential and supplemental solution to overcome the challenges of visual (RGB) imaging, such as the variation oflight conditions and revealing original human affect. Moreover, the thermal-basedimaging has shown promising results in the detection of psychophysiological signals, such as pulse rate and respiration rate in a contactless and noninvasive way.This paper presents a brief review on human affects and focuses on the advantages and challenges of the thermal imaging technique. In addition, this paper discusses the stages of thermal-based human affective state recognition, such asdataset type, preprocessing stage, region of interest (ROI), feature descriptors,and classification approaches with a brief performance analysis based on a number of works in the literature. This analysis could help beginners in the thermalimaging and affective recognition domain to explore numerous approaches usedby researchers to construct an affective state system based on thermal imaging.
基金supported by Key Emergency Project of Pneumonia Epidemic of Novel Coronavirus Infection of China,No.2020SK3006(to JL)Clinical Research Center for Medical Imaging in Hunan Province of China,No.2020SK4001(to JL)the Innovative Major Emergency Project Funding against the New Coronavirus Pneumonia in Hunan Province of China,No.2020SK3014(to JYL)。
文摘Although some short-term follow-up studies have found that individuals recovering from coronavirus disease 2019(COVID-19)exhibit anxiety,depression,and altered brain microstructure,their long-term physical problems,neuropsychiatric sequelae,and changes in brain function remain unknown.This observational cohort study collected 1-year follow-up data from 22 patients who had been hospitalized with COVID-19(8 males and 11 females,aged 54.2±8.7 years).Fatigue and myalgia were persistent symptoms at the 1-year follow-up.The resting state functional magnetic resonance imaging revealed that compared with 29 healthy controls(7 males and 18 females,aged 50.5±11.6 years),COVID-19 survivors had greatly increased amplitude of low-frequency fluctuation(ALFF)values in the left precentral gyrus,middle frontal gyrus,inferior frontal gyrus of operculum,inferior frontal gyrus of triangle,insula,hippocampus,parahippocampal gyrus,fusiform gyrus,postcentral gyrus,inferior parietal angular gyrus,supramarginal gyrus,angular gyrus,thalamus,middle temporal gyrus,inferior temporal gyrus,caudate,and putamen.ALFF values in the left caudate of the COVID-19 survivors were positively correlated with their Athens Insomnia Scale scores,and those in the left precentral gyrus were positively correlated with neutrophil count during hospitalization.The long-term follow-up results suggest that the ALFF in brain regions related to mood and sleep regulation were altered in COVID-19 survivors.This can help us understand the neurobiological mechanisms of COVID-19-related neuropsychiatric sequelae.This study was approved by the Ethics Committee of the Second Xiangya Hospital of Central South University(approval No.2020 S004)on March 19,2020.
