The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the...The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the analysis of saliva. A questionnaire survey was conducted among approximately 400 children from a primary school in Hiroshima. Parents were asked to complete the questionnaire and provide their contact information if they allowed the collection of saliva samples from their children. Thirty-eight chil- dren agreed to participate in the saliva study. Habit- ual snoring and cessation of breathing during sleep were found in approximately 8% and 1% of children, respectively. The present results showed significant correlations between snoring and mouth breathing. A significant association between excessive daytime sle- epiness (EDS) and learning problems was found. Fur- thermore, among children between the ages of 7 and 12 years, those with EDS and learning problems tended to be older. SDB symptom scores were statisti- cally significant only in relation to EDS. The present study also demonstrated significantly higher levels of salivary IgA and cortisol in children with sleep-re- lated disorders. The present study determined the pre- valence and characteristics of SDB among Japanese primary schoolchildren and their effects on the oral environment. Approximately 8% of primary school- children with habitual snoring might need to be care- fully monitored for SDB symptoms and immune sta- tus to ensure proper psychological and physical deve- lopment.展开更多
目的探究中医药领域艾滋病免疫功能重建的研究现状和热点,为该领域进一步研究提供参考。方法计算机检索中国知识资源总库、中国学术期刊数据库、中文科技期刊数据库、中国生物医学文献数据库、PubMed、Web of Science、Embase建库至2022...目的探究中医药领域艾滋病免疫功能重建的研究现状和热点,为该领域进一步研究提供参考。方法计算机检索中国知识资源总库、中国学术期刊数据库、中文科技期刊数据库、中国生物医学文献数据库、PubMed、Web of Science、Embase建库至2022年9月19日中医药领域艾滋病免疫功能重建相关文献,采用Excel2019、VOSviewer1.6.18和CiteSpace6.1.R6软件可视化分析年发文量、期刊、作者、机构和关键词。结果共纳入文献1367篇,其中,中文文献1220篇、英文文献147篇。年发文量呈波动上升趋势,中、英文文献载文量最高的期刊分别为《云南中医中药杂志》、Journal of Traditional Chinese Medicine,发文量最高的作者为徐立然、Wang Jian,中文文献发文量最高的研究机构为河南中医药大学、中国中医科学院。中文文献高频关键词有“艾滋病”“人类免疫缺陷病毒”“高效抗反转录病毒疗法”“中医药”“CD4^(+)T淋巴细胞”等,英文文献高频关键词有“acquired immunodeficiency syndrome”“hiv”“traditional Chinese medicine”“Chinese herbal medicine”“anti-hiv”等。关键词聚类分析生成中、英文文献各10个聚类标签。关键词突现分析得到中、英文文献各25个突现词。结论该领域在中药药理作用、作用机制、临床研究疗效评价、相关性疾病等方面研究热度较高且持续较久,肠道菌群、细胞凋亡等是新兴研究热点。展开更多
文摘The aim of this study was to assess the prevalence of sleep-disordered breathing (SDB) symptoms among primary schoolchildren, and to objectively determine the influence of SDB on the intra-oral environment through the analysis of saliva. A questionnaire survey was conducted among approximately 400 children from a primary school in Hiroshima. Parents were asked to complete the questionnaire and provide their contact information if they allowed the collection of saliva samples from their children. Thirty-eight chil- dren agreed to participate in the saliva study. Habit- ual snoring and cessation of breathing during sleep were found in approximately 8% and 1% of children, respectively. The present results showed significant correlations between snoring and mouth breathing. A significant association between excessive daytime sle- epiness (EDS) and learning problems was found. Fur- thermore, among children between the ages of 7 and 12 years, those with EDS and learning problems tended to be older. SDB symptom scores were statisti- cally significant only in relation to EDS. The present study also demonstrated significantly higher levels of salivary IgA and cortisol in children with sleep-re- lated disorders. The present study determined the pre- valence and characteristics of SDB among Japanese primary schoolchildren and their effects on the oral environment. Approximately 8% of primary school- children with habitual snoring might need to be care- fully monitored for SDB symptoms and immune sta- tus to ensure proper psychological and physical deve- lopment.
文摘目的探究中医药领域艾滋病免疫功能重建的研究现状和热点,为该领域进一步研究提供参考。方法计算机检索中国知识资源总库、中国学术期刊数据库、中文科技期刊数据库、中国生物医学文献数据库、PubMed、Web of Science、Embase建库至2022年9月19日中医药领域艾滋病免疫功能重建相关文献,采用Excel2019、VOSviewer1.6.18和CiteSpace6.1.R6软件可视化分析年发文量、期刊、作者、机构和关键词。结果共纳入文献1367篇,其中,中文文献1220篇、英文文献147篇。年发文量呈波动上升趋势,中、英文文献载文量最高的期刊分别为《云南中医中药杂志》、Journal of Traditional Chinese Medicine,发文量最高的作者为徐立然、Wang Jian,中文文献发文量最高的研究机构为河南中医药大学、中国中医科学院。中文文献高频关键词有“艾滋病”“人类免疫缺陷病毒”“高效抗反转录病毒疗法”“中医药”“CD4^(+)T淋巴细胞”等,英文文献高频关键词有“acquired immunodeficiency syndrome”“hiv”“traditional Chinese medicine”“Chinese herbal medicine”“anti-hiv”等。关键词聚类分析生成中、英文文献各10个聚类标签。关键词突现分析得到中、英文文献各25个突现词。结论该领域在中药药理作用、作用机制、临床研究疗效评价、相关性疾病等方面研究热度较高且持续较久,肠道菌群、细胞凋亡等是新兴研究热点。
