[Objective] This study was to evaluate the efficacy of instant asparagus powder, a functional food made of asparagus, for improving sleep quality. [Method] A total of 60 volunteers were selected, and each of them cons...[Objective] This study was to evaluate the efficacy of instant asparagus powder, a functional food made of asparagus, for improving sleep quality. [Method] A total of 60 volunteers were selected, and each of them consumed two bags of instant asparagus powder （24 g） once a day for 60 consecutive days. Then, the sleep quality of the volunteers was evaluated. At the same time, the safety indices and insomnia-related endocrine indices were determined. [Result] Instant asparagus powder significantly increased the sleep time of sleep disorders from 5.1 to 6.1 h, shortened the time to fall asleep from 50.4 to 25.3 rain, and reduced the time to fall asleep after being awake from 46.5 h to 19.5 h. The differences before and af- ter the consumption of instant asparagus powder were significant （P〈0.05）. The sat- isfaction of sleep quality was high. Instant asparagus powder had good safety with- out liver and kidney function influence. Instant asparagus powder could reduce the levels of cortisol and norepinepthrine and increase the levels of serotonin and dopamine. [Conclusion] Instant asparagus powder could improve the quality of sleep, characterized by safety and effectiveness. The sleep quality-improving effect of in- stant asparagus powder might be related to the regulation of HPA axis or the regu- lation of serotonin secretion.展开更多
目的观察降糖通便丸治疗糖尿病性便秘的临床疗效。方法符合诊断标准的患者63例随机分为两组。在常规治疗基础上,治疗组给予口服降糖通便丸(开封市中医院制剂室提供)治疗,对照组给予麻仁软胶囊治疗,观察两组临床疗效。停药2个月后随访,...目的观察降糖通便丸治疗糖尿病性便秘的临床疗效。方法符合诊断标准的患者63例随机分为两组。在常规治疗基础上,治疗组给予口服降糖通便丸(开封市中医院制剂室提供)治疗,对照组给予麻仁软胶囊治疗,观察两组临床疗效。停药2个月后随访,再了解两组排便情况。结果两组中医症状积分、空腹血糖(FBG)、餐后2 h血糖(2 h BG)、总胆固醇(TC)、甘油三酯(TG)较治疗前均有下降,差异有统计学意义(P<0.05);且治疗组优于对照组,差异有统计学意义(P<0.05)。治疗后两组组内比较,高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)较前均有改善,差异有统计学意义(P<0.05);组间比较差异无统计学意义(P>0.05)。但治疗组降低血脂水平总体优于对照组。治疗组总有效率96.78%,对照组总有效率90.62%,治疗组优于对照组,差异有统计学意义(P<0.05)。结论降糖通便丸治疗糖尿病性便秘临床疗效确切,显著改善患者临床症状及理化指标,提高患者生活治疗,值得临床推广应用。展开更多
基金Supported by Key Science and Technology Achievement Transformation Fund of Hebei Province(13042805Z)~~
文摘[Objective] This study was to evaluate the efficacy of instant asparagus powder, a functional food made of asparagus, for improving sleep quality. [Method] A total of 60 volunteers were selected, and each of them consumed two bags of instant asparagus powder （24 g） once a day for 60 consecutive days. Then, the sleep quality of the volunteers was evaluated. At the same time, the safety indices and insomnia-related endocrine indices were determined. [Result] Instant asparagus powder significantly increased the sleep time of sleep disorders from 5.1 to 6.1 h, shortened the time to fall asleep from 50.4 to 25.3 rain, and reduced the time to fall asleep after being awake from 46.5 h to 19.5 h. The differences before and af- ter the consumption of instant asparagus powder were significant （P〈0.05）. The sat- isfaction of sleep quality was high. Instant asparagus powder had good safety with- out liver and kidney function influence. Instant asparagus powder could reduce the levels of cortisol and norepinepthrine and increase the levels of serotonin and dopamine. [Conclusion] Instant asparagus powder could improve the quality of sleep, characterized by safety and effectiveness. The sleep quality-improving effect of in- stant asparagus powder might be related to the regulation of HPA axis or the regu- lation of serotonin secretion.
文摘目的观察降糖通便丸治疗糖尿病性便秘的临床疗效。方法符合诊断标准的患者63例随机分为两组。在常规治疗基础上,治疗组给予口服降糖通便丸(开封市中医院制剂室提供)治疗,对照组给予麻仁软胶囊治疗,观察两组临床疗效。停药2个月后随访,再了解两组排便情况。结果两组中医症状积分、空腹血糖(FBG)、餐后2 h血糖(2 h BG)、总胆固醇(TC)、甘油三酯(TG)较治疗前均有下降,差异有统计学意义(P<0.05);且治疗组优于对照组,差异有统计学意义(P<0.05)。治疗后两组组内比较,高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)较前均有改善,差异有统计学意义(P<0.05);组间比较差异无统计学意义(P>0.05)。但治疗组降低血脂水平总体优于对照组。治疗组总有效率96.78%,对照组总有效率90.62%,治疗组优于对照组,差异有统计学意义(P<0.05)。结论降糖通便丸治疗糖尿病性便秘临床疗效确切,显著改善患者临床症状及理化指标,提高患者生活治疗,值得临床推广应用。
