Nanomaterials and low-salinity water(LSW)are two popular enhanced oil recovery(EOR)methods that have been widely studied in recent years.The former is used for in-depth conformance improvement and the latter for micro...Nanomaterials and low-salinity water(LSW)are two popular enhanced oil recovery(EOR)methods that have been widely studied in recent years.The former is used for in-depth conformance improvement and the latter for microscopic oil displacement(by altering the potential and contact angle).However,there are few literature on combining them to achieve synergistic effects,especially for tight sandstone res-ervoirs.Based on the reservoir conditions of the Jimusar Oilfield,this study investigated the oil recovery mechanism of the combined imbibition system,which was composed of black nanosheet(BN)and LSW.Its performances including decreasing interfacial tension,emulsification,and wettability alterations were evaluated.The imbibition differences between the single system of BN and LSW and the combined BN-LsW imbibition system were then compared.Results showed that the combined imbibition system had a better emulsification effect on the crude oil and could also alter the wettability of the core surface.Moreover,the combined system could increase both the imbibition rate and the ultimate oil recovery.The nuclear magnetic T2 spectrum also indicated that the addition of black nanosheets could divert more fluid into small pores and thus improve the microscopic sweep efficiency.展开更多
Photoelectrochemical (PEC) small-molecule oxidation can selectively transform substrates into high-value-added fine chemicals and increase the rate of cathode hydrogen evolution. Nevertheless, achieving high-selectivi...Photoelectrochemical (PEC) small-molecule oxidation can selectively transform substrates into high-value-added fine chemicals and increase the rate of cathode hydrogen evolution. Nevertheless, achieving high-selectivity PEC oxidation of small molecules to produce specific products is a very challenging task. In general, selectivity can be improved by changing the surface catalyticsites of the photoanode and modulating the interfacial environments of the reactions. Herein, recent advances in approaches to improving selective PEC oxidation of small molecules are introduced. We first briefly discuss the basic concept and fundamentals of small-molecule PEC oxidation. The reported approaches to improving the performance of selective PEC oxidation of small molecules are highlighted from two aspects: (1) changing the surface properties of photoanodes by selecting suitable materials or modifying the photoanodes and (2) mediating the oxidation reactions using redox mediators. The PEC oxidation mechanism of these studies is emphasized. We also discuss the challenges in this research direction and offer a perspective on the further development of selective PEC-based small-molecule transformation.展开更多
Computer Algebra Systems have been extensively used in higher education. The reasons are many e.g., visualize mathematical problems, correlate real-world problems on a conceptual level, are flexible, simple to use, ac...Computer Algebra Systems have been extensively used in higher education. The reasons are many e.g., visualize mathematical problems, correlate real-world problems on a conceptual level, are flexible, simple to use, accessible from anywhere, etc. However, there is still room for improvement. Computer algebra system (CAS) optimization is the set of best practices and techniques to keep the CAS running optimally. Best practices are related to how to carry out a mathematical task or configure your system. In this paper, we are going to examine these techniques. The documentation sheets of CASs are the source of data that we used to compare them and examine their characteristics. The research results reveal that there are many tips that we can follow to accelerate performance.展开更多
BACKGROUND:Numerous medical conditions require timely medication administration in the emergency department(ED).Automated dispensing systems(ADSs)store premixed common doses at the point-of-care to minimize time to ad...BACKGROUND:Numerous medical conditions require timely medication administration in the emergency department(ED).Automated dispensing systems(ADSs)store premixed common doses at the point-of-care to minimize time to administration,but the use of such automation to improved time to medication administration has not been studied.Since vancomycin is a commonly used empiric antimicrobial,we sought to quantify the effect of using an ADS on time to drug delivery in patients presenting to the ED.The study aimed to determine the efficacy of utilizing an ADS to improve time to administration of vancomycin and determine any negative effects on dosing appropriateness.METHODS:The institional review board approved the retrospective quality improvement study took place in a single,urban academic tertiary care ED with an annual census of 80 000.Study subjects were all patients receiving vancomycin for the management of sepsis between March 1 to September 30,2008 and the same time period in 2009.The primary outcome was the proportion of patients who received vancomycin within one hour of bed placement and the secondary outcome was dosing appropriateness.RESULTS:Sixty-three patients had weight and dosing information available(29 before and 34after intervention)and were included in the study.Before intervention,no patient received vancomycin in less than 60 minutes,while after intervention 14.7%of the patients received it in less than 60minutes(difference in proportions 14.7%,95%CI 0.39%-30.0%,P=0.04).A similar proportion of the patients received correct dosing before and after intervention(44.8%vs.41.2%,difference in proportions 3.7%,95%CI-20.0%-26.7%,P=0.770).CONCLUSION:The use of an ADS may improve the timing of medication administration in patients presenting to the ED without affecting dosing appropriateness.展开更多
In this paper, the fixed-time event-triggered obstacle avoidance consensus control for a multi-AUV time-varying formation system in a 3D environment is presented by using an improved artificial potential field and lea...In this paper, the fixed-time event-triggered obstacle avoidance consensus control for a multi-AUV time-varying formation system in a 3D environment is presented by using an improved artificial potential field and leader-follower strategy(IAPF-LF). Firstly, the proposed fixed-time control can achieve the desired multi-AUV formation within a fixed settling time in any initial system state. Secondly, an event-triggered communication strategy is developed to govern the communication among AUVs, and the communication energy consumption can be decremented. The time-varying formation obstacle avoidance control algorithm based on IAPF-LF is designed to avoid static and dynamic obstacles, the desired formation is maintained in the presence of external disturbances, and there is no Zeno behavior under the fixed-time event-triggered consensus control strategy.The stability of the system is proved by the Lyapunov function and inequality scaling. Finally, simulation examples and water pool experiments are reported to verify the performance of the proposed theoretical algorithms.展开更多
This paper discusses an optimization of operating a p ermutation circulation-type vehicle routing system (PCVRS, for short), in w hich several stages are located along by a single loop, and a fleet of vehicles travels...This paper discusses an optimization of operating a p ermutation circulation-type vehicle routing system (PCVRS, for short), in w hich several stages are located along by a single loop, and a fleet of vehicles travels on the loop unidirectionally and repeatedly. Traveling on the loop, each vehicle receives an object from the loading stage and then carries it to a cert ain processing stage, or receives an object from a certain processing stage and then carries it to the unloading stage per a turnaround. No passing is allowed f or the vehicles on the loop (from which the system is called permutation, and th is restriction may cause interferences between vehicles). Material handling systems such as PCVRS are actually encountered in flexible man ufacturing systems and in automated storage/retrieval systems. In this paper, we propose a heuristic algorithm for operating the PCVRS, which i ncorporates a new scheduling method for the vehicles with the SPT (shortest proc essing time) numbering of jobs and a round-robin manner of allocating jobs to t he stages, aiming to reduce interferences between the vehicles. We also give num erical results with respect to system performances attained by the heuristic. Description of the system The PCVRS consists of a set of n v vehicles V={V 1,V 2,...,V n v}, a set of n s, processing stages S p={S 1,S 2,...,S n s}, a loading stage S 0 and an unloading stage S n s +1. We denote by S=S p∪{S 0,S n s+l} the set of all the stages. The vehicles travel on a single loop unidirectionany and repeated ly. The system layout is depicted in Fig.1. There is a set of n jobs J={J 1,J 2,...,J n} to be processed b y the vehicles. Each job consists of two tasks: That is, each vehicle receives a n object from S 0 and then carries it to S l with a certain l∈{1,2, ...,n s} (a throw-in job), or receives an object from S l with a certain l∈{1,2,...,n s} and then carries it to S n s+1 (a throw-out job ) per a turnaround. The loop consists of buffer zones BZ(l) and travel zones TZ(l) (see Fig. 1). Each buffer zone BZ(l) is placed in front of stage S l, l=0,1,..., n s, n s+1, in order to avoid a collision between vehicles (i.e., the syste m adopts the so-called zone control strategy). A heuristic algorithm We develop a heuristic algorithm to obtain a good performance for the PCVRS. An operation π={A/B/C} for the PCVRS consists of three decision factors: (A) Numbering jobs Jobs are loaded into S 0 according to an assending order of job numbers. In this paper, we use the following rules to number jobs: SPT: Order jobs in the shortest processing time rule, i.e., P 1≤P 2≤...≤P n for the set of jobs J={J 1,J 2,...,J n}, rather than the FCFS numbering (i.e., number jobs in first-come-first-served order). The SPT rule intends to reduce interferences between two adjacent vehicles at stages. (B) Allocating jobs to stages For the purpose of balancing loads of processing stages, we adopt the following to allocate jobs to the stages: ORDER: Allocate n jobs to n s, processing stages by an in-order manner , i.e., let l(i) be the index of processing stage allocated job J i by ORDER, it holds that l(i)=n s+1-(i-[(i-1)/n s]n s).(1) The ORDER rule intends to process jobs parallel at stages as many as possible. (C) Scheduling vehicles The following method for scheduling vehicles under ORDER rule is already known: Fig.1 The vehicle ro uting system, PCVRS Fig.2 Mean turnaroun d times by heuristics Unchange: Assign n jobs to n v vehicles such that let k(i) be the i ndex of vehicle processing job J i, then k(i)= i-[(i-1)/n v]n v.(2) In csse of n v≥n s, mod (n v,n s)=0 or n v<n s, mod (n s,n v)=0 (mod(x,y) is the remainder of x/y), the number of interferences between vehicles is minimized at stage S 1 under Unchange sche dules, while in the other cases it is not [Lu et al. (2001a)]. Therefore, in t his paper, we develop a new scheduling method of the vehicles, denoted by Ex change, to modify Unchange schedules. Note展开更多
The article describes the possibilities of application of simulation modeling for the analysis of infrastructure and technology of transport services of enterprises. The main technological and possible economic effect...The article describes the possibilities of application of simulation modeling for the analysis of infrastructure and technology of transport services of enterprises. The main technological and possible economic effects for the enterprises arising at performance of modeling of a transport component of their work are resulted.展开更多
Buildings represent a significant share of the world’s energy consumption,and the sector has drawn the attention of governments,which have adopted policies to reduce energy expenditure.The Certifications of Energy Ef...Buildings represent a significant share of the world’s energy consumption,and the sector has drawn the attention of governments,which have adopted policies to reduce energy expenditure.The Certifications of Energy Efficiency in Buildings stand out as one possible solution to achieve this goal,employed in several countries worldwide.The European Union presents advanced energy assessment programs for buildings,being a reference and model for several other regulations in the world.The Energy Certification System for Buildings(SCE)of Portugal is considered a success case,reflected in the significant number of energy certificates issued.The Brazilian Labeling Program for Building(PBE Edifica),first launched in 2009,does not find a broad application today in the Brazilian scenario.This work shows a synthesis of the European Energy Performance of Buildings Directive(EPBD)and the Brazilian and Portuguese regulations’history.A qualitative comparison is made between the SCE and the PBE Edifica to verify a European and a developing country’s regulations with a certain degree of cultural and climatic similarities.Through this comparison,proposals are made for improvements to Brazilian certification,seeking to improve its energy planning and energy policy concerning its building stock.The suggestions for improvement presented may also be appropriate for other developing countries that have started and have not yet successfully implemented their energy certification programs in buildings.展开更多
Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of di...Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of diagnosis and improvement.To address the current dilemma of building internal quality assurance systems in higher education institutions,this study utilizes a case study approach.This study takes Jingzhou Vocational and Technical College as the research object for research.Conclusion:The excellent diagnosis and reform model and the effectiveness of diagnosis and reform in this school can provide new strategic ideas for the practice of diagnosis and reform for the high-quality development of higher education in Hubei.展开更多
Patient safety is a serious global health issue.Nurses play a critical role in improving patient safety.This Special Focus Issue aims to report research and evidence-based practice about patient safety.This special is...Patient safety is a serious global health issue.Nurses play a critical role in improving patient safety.This Special Focus Issue aims to report research and evidence-based practice about patient safety.This special issue welcomes original research papers,perspectives,conceptual papers,case reports,systematic reviews,and scoping review articles that address a range of topics including,but not limited to,the following areas:The four Cs of safety:Culture,Competency,Consequences&Continuous improvement.展开更多
Graphene flakes(GF)have been prepared and assessed as a material for improving flow in oil pipelines under the effect of an electric field.In particular,different amounts of GFs have been considered in order to determ...Graphene flakes(GF)have been prepared and assessed as a material for improving flow in oil pipelines under the effect of an electric field.In particular,different amounts of GFs have been considered in order to determine the optimal flow conditions.The GFs were prepared from graphite foam,derived from the dehydration of sugar with a particle size of 500-600μm,which was dispersed in ethanol and exfoliated in a ball mill under a shear force.After 15 h of exfoliation,sonication,and subsequent high-speed centrifugation at 3000 rpm,irregular-shaped GFs of 50-140 nm were produced and characterized using scanning electron microscopy,X-ray diffractometry,atomic force microscopy,and Raman spectroscopy.The prepared graphene sheets have been found to display excellent morphology and good graphitic structure.Experiments on flow improvement were conducted using the central composite rotatable design method for three parameters:stimulation time(15,30,45,and 60 s),applied voltage(150,170,200,and 220 V),and concentration of the GFs(0,100,200,and 400 mg/L).The optimal conditions for improved crude oil flow were then determined using the STATISTICA and WinQSB software packages.The results have confirmed the effectiveness of the use of the prepared GFs as a flow improver for crude oil,where the flow improvement is essentially a result of a reduction in viscosity and suppression of friction in the crude oil system.展开更多
Mobile Ad-hoc Networks(MANETs)connect numerous nodes to communicate data from the sender node to the target node.Due to the lack of an infrastructure network,mobile nodes communicate through wireless without an access...Mobile Ad-hoc Networks(MANETs)connect numerous nodes to communicate data from the sender node to the target node.Due to the lack of an infrastructure network,mobile nodes communicate through wireless without an access point.MANET does not have a centralized controller and has a dynamic network topology,which increases link failure and energy consumption resulting in excessive path delay,loss of Quality of service(QoS),and reduced throughput during data communication.Congestion is a significant problem when the QoS of the link carrying the data is degraded.Routing is one of the vital challenges of MANET due to the very dynamic and distributed nature of MANET.This article introduces a Mobility-Based Optimized Multipath Routing Protocol(MBOMRP)and an Efficient Reliable Link-State Transmission(ERLST)algorithm to overcome these problems.The proposed Mobility-Based Optimized Multipath Routing Protocol(MBOMRP)is utilized for route discovery and maintenance to efficiently avoid traffic and sleeping nodes.ERLST algorithm is used for efficient data transmission to increase QoS measurement parameters like throughput,Packet Delivery Ratio(PDR),and minimize the latency performance.The proposed MBOMRP-ERLST algorithm improves data communication network lifetime,avoids link failures,and provides efficient results compared with previous algorithms.展开更多
Many approaches to neurodegenerative diseases that focus on amyloid-βclearance and gene therapy have not been successful.Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis...Many approaches to neurodegenerative diseases that focus on amyloid-βclearance and gene therapy have not been successful.Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases,including mitochondrial dysfunction.Plasma membrane(PM)redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction.Neurohormetic phytochemicals are known to induce the expression of detoxifying enzymes under stress conditions.In this study,mechanisms of neuroprotective effects of 4-hydroxycinnamic acid(HCA)were examined by analyzing cell survival,levels of abnormal proteins,and mitochondrial functions in two different neuronal cells.HCA protected two neuronal cells exhibited high expression of PM redox enzymes and the consequent increase in the NAD^(+)/NADH ratio.Cells cultured with HCA showed delayed apoptosis and decreased oxidative/nitrative damage accompanied by decreased ROS production in the mitochondria.HCA increased the mitochondrial complexes I and II activities and ATP production.Also,HCA increased mitochondrial fusion and decreased mitochondrial fission.Overall,HCA maintains redox homeostasis and energy metabolism under oxidative/metabolic stress conditions.These findings suggest that HCA could be a promising therapeutic approach for neurodegenerative diseases.展开更多
This paper is concerned with the cooperative target stalking for a multi-unmanned surface vehicle(multi-USV)system.Based on the multi-agent deep deterministic policy gradient(MADDPG)algorithm,a multi-USV target stalki...This paper is concerned with the cooperative target stalking for a multi-unmanned surface vehicle(multi-USV)system.Based on the multi-agent deep deterministic policy gradient(MADDPG)algorithm,a multi-USV target stalking(MUTS)algorithm is proposed.Firstly,a V-type probabilistic data extraction method is proposed for the first time to overcome shortcomings of the MADDPG algorithm.The advantages of the proposed method are twofold:1)it can reduce the amount of data and shorten training time;2)it can filter out more important data in the experience buffer for training.Secondly,in order to avoid the collisions of USVs during the stalking process,an action constraint method called Safe DDPG is introduced.Finally,the MUTS algorithm and some existing algorithms are compared in cooperative target stalking scenarios.In order to demonstrate the effectiveness of the proposed MUTS algorithm in stalking tasks,mission operating scenarios and reward functions are well designed in this paper.The proposed MUTS algorithm can help the multi-USV system avoid internal collisions during the mission execution.Moreover,compared with some existing algorithms,the newly proposed one can provide a higher convergence speed and a narrower convergence domain.展开更多
The generation of electricity based on renewable energy sources,parti-cularly Photovoltaic(PV)system has been greatly increased and it is simply insti-gated for both domestic and commercial uses.The power generated fr...The generation of electricity based on renewable energy sources,parti-cularly Photovoltaic(PV)system has been greatly increased and it is simply insti-gated for both domestic and commercial uses.The power generated from the PV system is erratic and hence there is a need for an efficient converter to perform the extraction of maximum power.An improved interleaved Single-ended Primary Inductor-Converter(SEPIC)converter is employed in proposed work to extricate most of power from renewable source.This proposed converter minimizes ripples,reduces electromagnetic interference due tofilter elements and the contin-uous input current improves the power output of PV panel.A Crow Search Algo-rithm(CSA)based Proportional Integral(PI)controller is utilized for controlling the converter switches effectively by optimizing the parameters of PI controller.The optimized PI controller reduces ripples present in Direct Current(DC)vol-tage,maintains constant voltage at proposed converter output and reduces over-shoots with minimum settling and rise time.This voltage is given to single phase grid via 1�Voltage Source Inverter(VSI).The command pulses of 1�VSI are produced by simple PI controller.The response of the proposed converter is thus improved with less input current.After implementing CSA based PI the efficiency of proposed converter obtained is 96%and the Total Harmonic Distor-tion(THD)is found to be 2:4%.The dynamics and closed loop operation is designed and modeled using MATLAB Simulink tool and its behavior is performed.展开更多
Typically,smart grid systems enhance the ability of conventional power system networks as it is vulnerable to several kinds of attacks.These vulnerabil-ities might cause the attackers or intruders to collapse the enti...Typically,smart grid systems enhance the ability of conventional power system networks as it is vulnerable to several kinds of attacks.These vulnerabil-ities might cause the attackers or intruders to collapse the entire network system thus breaching the confidentiality and integrity of smart grid systems.Thus,for this purpose,Intrusion detection system(IDS)plays a pivotal part in offering a reliable and secured range of services in the smart grid framework.Several exist-ing approaches are there to detect the intrusions in smart grid framework,however they are utilizing an old dataset to detect anomaly thus resulting in reduced rate of detection accuracy in real-time and huge data sources.So as to overcome these limitations,the proposed technique is presented which employs both real-time raw data from the smart grid network and KDD99 dataset thus detecting anoma-lies in the smart grid network.In the grid side data acquisition,the power trans-mitted to the grid is checked and enhanced in terms of power quality by eradicating distortion in transmission lines.In this approach,power quality in the smart grid network is enhanced by rectifying the fault using a FACT device termed UPQC(Unified Power Quality Controller)and thereby storing the data in cloud storage.The data from smart grid cloud storage and KDD99 are pre-pro-cessed and are optimized using Improved Aquila Swarm Optimization(IASO)to extract optimal features.The probabilistic Recurrent Neural Network(PRNN)classifier is then employed for the prediction and classification of intrusions.At last,the performance is estimated and the outcomes are projected in terms of grid voltage,grid current,Total Harmonic Distortion(THD),voltage sag/swell,accu-racy,precision,recall,F-score,false acceptance rate(FAR),and detection rate of the classifier.The analysis is compared with existing techniques to validate the proposed model efficiency.展开更多
One of the major problems in the education sector is the reading skills of learners.Students enrolled in the Alternative Learning System(ALS)also experienced this scenario due to several circumstances.This study focus...One of the major problems in the education sector is the reading skills of learners.Students enrolled in the Alternative Learning System(ALS)also experienced this scenario due to several circumstances.This study focused on the improvement of reading comprehension skills of ALS learners by means of project RICE(Reading Intervention and Comprehension Enhancement)as well as the issues and challenges.A quasi-experimental design was utilized in this study which was participated by 54 learners,composed of 27 learners under the experimental group and 27 under the control group.The result revealed that the learners in the experimental group changed from frustration level to instructional level after the implementation of project RICE while the learners in the control group changed from instructional level to inde-pendent level,thereby signifying a significant difference and the effectiveness of the project.Additionally,issues with time and resources were often encountered by the learners.展开更多
Highway test and detection technology play a very important role in controlling the quality of road and bridge engineering and improving the maintenance of roads and bridges.The study of highway bridge test detection ...Highway test and detection technology play a very important role in controlling the quality of road and bridge engineering and improving the maintenance of roads and bridges.The study of highway bridge test detection technology is both theoretically and practically useful.Road and bridge test and detection is a complicated task.With the development of science and technology,highway and bridge engineering test and detection technology has also made great progress.The continuous improvement of test and detection technology has brought good social benefits to road and bridge construction.This article discusses the problems in test and detection technology of highway bridges and how to improve the quality of test and detection.展开更多
基金funded by the Karamay Innovative Environment Construction Plan(Innovative Talents)Project(No.20212022hjcxrc0015)the Research Foundation of China University of Petroleum-Beijing at Karamay(No.XQZX20200010)+3 种基金the University Scientific Research Project of Xinjiang Uygur Autonomous Region(No.XJEDU2019Y067)the Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2019D01B57)the CNPC Strategic Cooperation Science and Technology Project(No.ZLZX2020-01-04-04)the Sichuan Province Regional Innovation Cooperation Project(No.2020YFQ0036).
文摘Nanomaterials and low-salinity water(LSW)are two popular enhanced oil recovery(EOR)methods that have been widely studied in recent years.The former is used for in-depth conformance improvement and the latter for microscopic oil displacement(by altering the potential and contact angle).However,there are few literature on combining them to achieve synergistic effects,especially for tight sandstone res-ervoirs.Based on the reservoir conditions of the Jimusar Oilfield,this study investigated the oil recovery mechanism of the combined imbibition system,which was composed of black nanosheet(BN)and LSW.Its performances including decreasing interfacial tension,emulsification,and wettability alterations were evaluated.The imbibition differences between the single system of BN and LSW and the combined BN-LsW imbibition system were then compared.Results showed that the combined imbibition system had a better emulsification effect on the crude oil and could also alter the wettability of the core surface.Moreover,the combined system could increase both the imbibition rate and the ultimate oil recovery.The nuclear magnetic T2 spectrum also indicated that the addition of black nanosheets could divert more fluid into small pores and thus improve the microscopic sweep efficiency.
基金the National Natural Science Foundation of China (No. 22136005)the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB36000000).
文摘Photoelectrochemical (PEC) small-molecule oxidation can selectively transform substrates into high-value-added fine chemicals and increase the rate of cathode hydrogen evolution. Nevertheless, achieving high-selectivity PEC oxidation of small molecules to produce specific products is a very challenging task. In general, selectivity can be improved by changing the surface catalyticsites of the photoanode and modulating the interfacial environments of the reactions. Herein, recent advances in approaches to improving selective PEC oxidation of small molecules are introduced. We first briefly discuss the basic concept and fundamentals of small-molecule PEC oxidation. The reported approaches to improving the performance of selective PEC oxidation of small molecules are highlighted from two aspects: (1) changing the surface properties of photoanodes by selecting suitable materials or modifying the photoanodes and (2) mediating the oxidation reactions using redox mediators. The PEC oxidation mechanism of these studies is emphasized. We also discuss the challenges in this research direction and offer a perspective on the further development of selective PEC-based small-molecule transformation.
文摘Computer Algebra Systems have been extensively used in higher education. The reasons are many e.g., visualize mathematical problems, correlate real-world problems on a conceptual level, are flexible, simple to use, accessible from anywhere, etc. However, there is still room for improvement. Computer algebra system (CAS) optimization is the set of best practices and techniques to keep the CAS running optimally. Best practices are related to how to carry out a mathematical task or configure your system. In this paper, we are going to examine these techniques. The documentation sheets of CASs are the source of data that we used to compare them and examine their characteristics. The research results reveal that there are many tips that we can follow to accelerate performance.
基金supported by a Resident Research Grant from the University of Cincinnati Department of Emergency Medicineby a Research Fellowship Award from the Emergency Medicine Foundationby an Institutional Clinicaland Translational Science Award,NIH/NCRR Grant Number 5UL1RR026314-02
文摘BACKGROUND:Numerous medical conditions require timely medication administration in the emergency department(ED).Automated dispensing systems(ADSs)store premixed common doses at the point-of-care to minimize time to administration,but the use of such automation to improved time to medication administration has not been studied.Since vancomycin is a commonly used empiric antimicrobial,we sought to quantify the effect of using an ADS on time to drug delivery in patients presenting to the ED.The study aimed to determine the efficacy of utilizing an ADS to improve time to administration of vancomycin and determine any negative effects on dosing appropriateness.METHODS:The institional review board approved the retrospective quality improvement study took place in a single,urban academic tertiary care ED with an annual census of 80 000.Study subjects were all patients receiving vancomycin for the management of sepsis between March 1 to September 30,2008 and the same time period in 2009.The primary outcome was the proportion of patients who received vancomycin within one hour of bed placement and the secondary outcome was dosing appropriateness.RESULTS:Sixty-three patients had weight and dosing information available(29 before and 34after intervention)and were included in the study.Before intervention,no patient received vancomycin in less than 60 minutes,while after intervention 14.7%of the patients received it in less than 60minutes(difference in proportions 14.7%,95%CI 0.39%-30.0%,P=0.04).A similar proportion of the patients received correct dosing before and after intervention(44.8%vs.41.2%,difference in proportions 3.7%,95%CI-20.0%-26.7%,P=0.770).CONCLUSION:The use of an ADS may improve the timing of medication administration in patients presenting to the ED without affecting dosing appropriateness.
基金supported in part by the National Natural Science Foundation of China (62033009)the Creative Activity Plan for Science and Technology Commission of Shanghai (20510712300,21DZ2293500)the Supported by Science Foundation of Donghai Laboratory。
文摘In this paper, the fixed-time event-triggered obstacle avoidance consensus control for a multi-AUV time-varying formation system in a 3D environment is presented by using an improved artificial potential field and leader-follower strategy(IAPF-LF). Firstly, the proposed fixed-time control can achieve the desired multi-AUV formation within a fixed settling time in any initial system state. Secondly, an event-triggered communication strategy is developed to govern the communication among AUVs, and the communication energy consumption can be decremented. The time-varying formation obstacle avoidance control algorithm based on IAPF-LF is designed to avoid static and dynamic obstacles, the desired formation is maintained in the presence of external disturbances, and there is no Zeno behavior under the fixed-time event-triggered consensus control strategy.The stability of the system is proved by the Lyapunov function and inequality scaling. Finally, simulation examples and water pool experiments are reported to verify the performance of the proposed theoretical algorithms.
文摘This paper discusses an optimization of operating a p ermutation circulation-type vehicle routing system (PCVRS, for short), in w hich several stages are located along by a single loop, and a fleet of vehicles travels on the loop unidirectionally and repeatedly. Traveling on the loop, each vehicle receives an object from the loading stage and then carries it to a cert ain processing stage, or receives an object from a certain processing stage and then carries it to the unloading stage per a turnaround. No passing is allowed f or the vehicles on the loop (from which the system is called permutation, and th is restriction may cause interferences between vehicles). Material handling systems such as PCVRS are actually encountered in flexible man ufacturing systems and in automated storage/retrieval systems. In this paper, we propose a heuristic algorithm for operating the PCVRS, which i ncorporates a new scheduling method for the vehicles with the SPT (shortest proc essing time) numbering of jobs and a round-robin manner of allocating jobs to t he stages, aiming to reduce interferences between the vehicles. We also give num erical results with respect to system performances attained by the heuristic. Description of the system The PCVRS consists of a set of n v vehicles V={V 1,V 2,...,V n v}, a set of n s, processing stages S p={S 1,S 2,...,S n s}, a loading stage S 0 and an unloading stage S n s +1. We denote by S=S p∪{S 0,S n s+l} the set of all the stages. The vehicles travel on a single loop unidirectionany and repeated ly. The system layout is depicted in Fig.1. There is a set of n jobs J={J 1,J 2,...,J n} to be processed b y the vehicles. Each job consists of two tasks: That is, each vehicle receives a n object from S 0 and then carries it to S l with a certain l∈{1,2, ...,n s} (a throw-in job), or receives an object from S l with a certain l∈{1,2,...,n s} and then carries it to S n s+1 (a throw-out job ) per a turnaround. The loop consists of buffer zones BZ(l) and travel zones TZ(l) (see Fig. 1). Each buffer zone BZ(l) is placed in front of stage S l, l=0,1,..., n s, n s+1, in order to avoid a collision between vehicles (i.e., the syste m adopts the so-called zone control strategy). A heuristic algorithm We develop a heuristic algorithm to obtain a good performance for the PCVRS. An operation π={A/B/C} for the PCVRS consists of three decision factors: (A) Numbering jobs Jobs are loaded into S 0 according to an assending order of job numbers. In this paper, we use the following rules to number jobs: SPT: Order jobs in the shortest processing time rule, i.e., P 1≤P 2≤...≤P n for the set of jobs J={J 1,J 2,...,J n}, rather than the FCFS numbering (i.e., number jobs in first-come-first-served order). The SPT rule intends to reduce interferences between two adjacent vehicles at stages. (B) Allocating jobs to stages For the purpose of balancing loads of processing stages, we adopt the following to allocate jobs to the stages: ORDER: Allocate n jobs to n s, processing stages by an in-order manner , i.e., let l(i) be the index of processing stage allocated job J i by ORDER, it holds that l(i)=n s+1-(i-[(i-1)/n s]n s).(1) The ORDER rule intends to process jobs parallel at stages as many as possible. (C) Scheduling vehicles The following method for scheduling vehicles under ORDER rule is already known: Fig.1 The vehicle ro uting system, PCVRS Fig.2 Mean turnaroun d times by heuristics Unchange: Assign n jobs to n v vehicles such that let k(i) be the i ndex of vehicle processing job J i, then k(i)= i-[(i-1)/n v]n v.(2) In csse of n v≥n s, mod (n v,n s)=0 or n v<n s, mod (n s,n v)=0 (mod(x,y) is the remainder of x/y), the number of interferences between vehicles is minimized at stage S 1 under Unchange sche dules, while in the other cases it is not [Lu et al. (2001a)]. Therefore, in t his paper, we develop a new scheduling method of the vehicles, denoted by Ex change, to modify Unchange schedules. Note
文摘The article describes the possibilities of application of simulation modeling for the analysis of infrastructure and technology of transport services of enterprises. The main technological and possible economic effects for the enterprises arising at performance of modeling of a transport component of their work are resulted.
文摘Buildings represent a significant share of the world’s energy consumption,and the sector has drawn the attention of governments,which have adopted policies to reduce energy expenditure.The Certifications of Energy Efficiency in Buildings stand out as one possible solution to achieve this goal,employed in several countries worldwide.The European Union presents advanced energy assessment programs for buildings,being a reference and model for several other regulations in the world.The Energy Certification System for Buildings(SCE)of Portugal is considered a success case,reflected in the significant number of energy certificates issued.The Brazilian Labeling Program for Building(PBE Edifica),first launched in 2009,does not find a broad application today in the Brazilian scenario.This work shows a synthesis of the European Energy Performance of Buildings Directive(EPBD)and the Brazilian and Portuguese regulations’history.A qualitative comparison is made between the SCE and the PBE Edifica to verify a European and a developing country’s regulations with a certain degree of cultural and climatic similarities.Through this comparison,proposals are made for improvements to Brazilian certification,seeking to improve its energy planning and energy policy concerning its building stock.The suggestions for improvement presented may also be appropriate for other developing countries that have started and have not yet successfully implemented their energy certification programs in buildings.
文摘Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of diagnosis and improvement.To address the current dilemma of building internal quality assurance systems in higher education institutions,this study utilizes a case study approach.This study takes Jingzhou Vocational and Technical College as the research object for research.Conclusion:The excellent diagnosis and reform model and the effectiveness of diagnosis and reform in this school can provide new strategic ideas for the practice of diagnosis and reform for the high-quality development of higher education in Hubei.
文摘Patient safety is a serious global health issue.Nurses play a critical role in improving patient safety.This Special Focus Issue aims to report research and evidence-based practice about patient safety.This special issue welcomes original research papers,perspectives,conceptual papers,case reports,systematic reviews,and scoping review articles that address a range of topics including,but not limited to,the following areas:The four Cs of safety:Culture,Competency,Consequences&Continuous improvement.
文摘Graphene flakes(GF)have been prepared and assessed as a material for improving flow in oil pipelines under the effect of an electric field.In particular,different amounts of GFs have been considered in order to determine the optimal flow conditions.The GFs were prepared from graphite foam,derived from the dehydration of sugar with a particle size of 500-600μm,which was dispersed in ethanol and exfoliated in a ball mill under a shear force.After 15 h of exfoliation,sonication,and subsequent high-speed centrifugation at 3000 rpm,irregular-shaped GFs of 50-140 nm were produced and characterized using scanning electron microscopy,X-ray diffractometry,atomic force microscopy,and Raman spectroscopy.The prepared graphene sheets have been found to display excellent morphology and good graphitic structure.Experiments on flow improvement were conducted using the central composite rotatable design method for three parameters:stimulation time(15,30,45,and 60 s),applied voltage(150,170,200,and 220 V),and concentration of the GFs(0,100,200,and 400 mg/L).The optimal conditions for improved crude oil flow were then determined using the STATISTICA and WinQSB software packages.The results have confirmed the effectiveness of the use of the prepared GFs as a flow improver for crude oil,where the flow improvement is essentially a result of a reduction in viscosity and suppression of friction in the crude oil system.
文摘Mobile Ad-hoc Networks(MANETs)connect numerous nodes to communicate data from the sender node to the target node.Due to the lack of an infrastructure network,mobile nodes communicate through wireless without an access point.MANET does not have a centralized controller and has a dynamic network topology,which increases link failure and energy consumption resulting in excessive path delay,loss of Quality of service(QoS),and reduced throughput during data communication.Congestion is a significant problem when the QoS of the link carrying the data is degraded.Routing is one of the vital challenges of MANET due to the very dynamic and distributed nature of MANET.This article introduces a Mobility-Based Optimized Multipath Routing Protocol(MBOMRP)and an Efficient Reliable Link-State Transmission(ERLST)algorithm to overcome these problems.The proposed Mobility-Based Optimized Multipath Routing Protocol(MBOMRP)is utilized for route discovery and maintenance to efficiently avoid traffic and sleeping nodes.ERLST algorithm is used for efficient data transmission to increase QoS measurement parameters like throughput,Packet Delivery Ratio(PDR),and minimize the latency performance.The proposed MBOMRP-ERLST algorithm improves data communication network lifetime,avoids link failures,and provides efficient results compared with previous algorithms.
基金supported by the National Research Foundation of Korea(NRF)of the Korean Government(NRF-2021R1F1A1051212)by Logsynk Co.Ltd.(2-2021-1435-001).
文摘Many approaches to neurodegenerative diseases that focus on amyloid-βclearance and gene therapy have not been successful.Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases,including mitochondrial dysfunction.Plasma membrane(PM)redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction.Neurohormetic phytochemicals are known to induce the expression of detoxifying enzymes under stress conditions.In this study,mechanisms of neuroprotective effects of 4-hydroxycinnamic acid(HCA)were examined by analyzing cell survival,levels of abnormal proteins,and mitochondrial functions in two different neuronal cells.HCA protected two neuronal cells exhibited high expression of PM redox enzymes and the consequent increase in the NAD^(+)/NADH ratio.Cells cultured with HCA showed delayed apoptosis and decreased oxidative/nitrative damage accompanied by decreased ROS production in the mitochondria.HCA increased the mitochondrial complexes I and II activities and ATP production.Also,HCA increased mitochondrial fusion and decreased mitochondrial fission.Overall,HCA maintains redox homeostasis and energy metabolism under oxidative/metabolic stress conditions.These findings suggest that HCA could be a promising therapeutic approach for neurodegenerative diseases.
基金supported in part by the National Natural Science Foundation of China(61873335,61833011,62173164)the Project of Science and Technology Commission of Shanghai Municipality,China(20ZR1420200,21SQBS01600,22JC1401400,19510750300,21190780300)the Natural Science Foundation of Jiangsu Province of China(BK20201451)。
文摘This paper is concerned with the cooperative target stalking for a multi-unmanned surface vehicle(multi-USV)system.Based on the multi-agent deep deterministic policy gradient(MADDPG)algorithm,a multi-USV target stalking(MUTS)algorithm is proposed.Firstly,a V-type probabilistic data extraction method is proposed for the first time to overcome shortcomings of the MADDPG algorithm.The advantages of the proposed method are twofold:1)it can reduce the amount of data and shorten training time;2)it can filter out more important data in the experience buffer for training.Secondly,in order to avoid the collisions of USVs during the stalking process,an action constraint method called Safe DDPG is introduced.Finally,the MUTS algorithm and some existing algorithms are compared in cooperative target stalking scenarios.In order to demonstrate the effectiveness of the proposed MUTS algorithm in stalking tasks,mission operating scenarios and reward functions are well designed in this paper.The proposed MUTS algorithm can help the multi-USV system avoid internal collisions during the mission execution.Moreover,compared with some existing algorithms,the newly proposed one can provide a higher convergence speed and a narrower convergence domain.
文摘The generation of electricity based on renewable energy sources,parti-cularly Photovoltaic(PV)system has been greatly increased and it is simply insti-gated for both domestic and commercial uses.The power generated from the PV system is erratic and hence there is a need for an efficient converter to perform the extraction of maximum power.An improved interleaved Single-ended Primary Inductor-Converter(SEPIC)converter is employed in proposed work to extricate most of power from renewable source.This proposed converter minimizes ripples,reduces electromagnetic interference due tofilter elements and the contin-uous input current improves the power output of PV panel.A Crow Search Algo-rithm(CSA)based Proportional Integral(PI)controller is utilized for controlling the converter switches effectively by optimizing the parameters of PI controller.The optimized PI controller reduces ripples present in Direct Current(DC)vol-tage,maintains constant voltage at proposed converter output and reduces over-shoots with minimum settling and rise time.This voltage is given to single phase grid via 1�Voltage Source Inverter(VSI).The command pulses of 1�VSI are produced by simple PI controller.The response of the proposed converter is thus improved with less input current.After implementing CSA based PI the efficiency of proposed converter obtained is 96%and the Total Harmonic Distor-tion(THD)is found to be 2:4%.The dynamics and closed loop operation is designed and modeled using MATLAB Simulink tool and its behavior is performed.
文摘Typically,smart grid systems enhance the ability of conventional power system networks as it is vulnerable to several kinds of attacks.These vulnerabil-ities might cause the attackers or intruders to collapse the entire network system thus breaching the confidentiality and integrity of smart grid systems.Thus,for this purpose,Intrusion detection system(IDS)plays a pivotal part in offering a reliable and secured range of services in the smart grid framework.Several exist-ing approaches are there to detect the intrusions in smart grid framework,however they are utilizing an old dataset to detect anomaly thus resulting in reduced rate of detection accuracy in real-time and huge data sources.So as to overcome these limitations,the proposed technique is presented which employs both real-time raw data from the smart grid network and KDD99 dataset thus detecting anoma-lies in the smart grid network.In the grid side data acquisition,the power trans-mitted to the grid is checked and enhanced in terms of power quality by eradicating distortion in transmission lines.In this approach,power quality in the smart grid network is enhanced by rectifying the fault using a FACT device termed UPQC(Unified Power Quality Controller)and thereby storing the data in cloud storage.The data from smart grid cloud storage and KDD99 are pre-pro-cessed and are optimized using Improved Aquila Swarm Optimization(IASO)to extract optimal features.The probabilistic Recurrent Neural Network(PRNN)classifier is then employed for the prediction and classification of intrusions.At last,the performance is estimated and the outcomes are projected in terms of grid voltage,grid current,Total Harmonic Distortion(THD),voltage sag/swell,accu-racy,precision,recall,F-score,false acceptance rate(FAR),and detection rate of the classifier.The analysis is compared with existing techniques to validate the proposed model efficiency.
文摘One of the major problems in the education sector is the reading skills of learners.Students enrolled in the Alternative Learning System(ALS)also experienced this scenario due to several circumstances.This study focused on the improvement of reading comprehension skills of ALS learners by means of project RICE(Reading Intervention and Comprehension Enhancement)as well as the issues and challenges.A quasi-experimental design was utilized in this study which was participated by 54 learners,composed of 27 learners under the experimental group and 27 under the control group.The result revealed that the learners in the experimental group changed from frustration level to instructional level after the implementation of project RICE while the learners in the control group changed from instructional level to inde-pendent level,thereby signifying a significant difference and the effectiveness of the project.Additionally,issues with time and resources were often encountered by the learners.
文摘Highway test and detection technology play a very important role in controlling the quality of road and bridge engineering and improving the maintenance of roads and bridges.The study of highway bridge test detection technology is both theoretically and practically useful.Road and bridge test and detection is a complicated task.With the development of science and technology,highway and bridge engineering test and detection technology has also made great progress.The continuous improvement of test and detection technology has brought good social benefits to road and bridge construction.This article discusses the problems in test and detection technology of highway bridges and how to improve the quality of test and detection.