AIM： To investigate the functional networks underlying the brain-activity changes of patients with high myopia using the voxel-wise degree centrality（DC） method.METHODS： In total, 38 patients with high myopia（HM...AIM： To investigate the functional networks underlying the brain-activity changes of patients with high myopia using the voxel-wise degree centrality（DC） method.METHODS： In total, 38 patients with high myopia（HM）（17 males and 21 females）, whose binocular refractive diopter were-6.00 to-7.00 D, and 38 healthy controls（17 males and 21 females）, closely matched in age, sex, and education levels, participated in the study. Spontaneous brain activities were evaluated using the voxel-wise DC method. The receiver operating characteristic curve was measured to distinguish patients with HM from healthy controls. Correlation analysis was used to explore the relationship between the observed mean DC values of the different brain areas and the behavioral performance.RESULTS： Compared with healthy controls, HM patients had significantly decreased DC values in the right inferior frontal gyrus/insula, right middle frontal gyrus, and right supramarginal/inferior parietal lobule（P〈0.05）. In contrast, HM patients had significantly increased DC values in the right cerebellum posterior lobe, left precentral gyrus/postcentral gyrus, and right middle cingulate gyrus（P〈0.05）. However, no relationship was found between the observed mean DC values of the different brain areas and the behavioral performance（P〉0.05）.CONCLUSION： HM is associated with abnormalities in many brain regions, which may indicate the neural mechanisms of HM. The altered DC values may be used as a useful biomarker for the brain activity changes in HM patients.展开更多
It is proved that if the degree of any non-linear irreducible character of a finite group G is a product of powers of two given distinct prime integers p and q, then G has an abelian Hall {p, q} subgroup H and an Abel...It is proved that if the degree of any non-linear irreducible character of a finite group G is a product of powers of two given distinct prime integers p and q, then G has an abelian Hall {p, q} subgroup H and an Abelian normal {p, q} complement A, and the centralizer in A of the Sylow p-subgroup of G is equal to the centralizer in A of the Sylow q-subgroup of G.展开更多
AIM:To explore the intrinsic brain activity variations in retinal vein occlusion(RVO)subjects by using the voxel-wise degree centrality(DC)technique.METHODS:Twenty-one subjects with RVO and twentyone healthy controls(...AIM:To explore the intrinsic brain activity variations in retinal vein occlusion(RVO)subjects by using the voxel-wise degree centrality(DC)technique.METHODS:Twenty-one subjects with RVO and twentyone healthy controls(HCs)were enlisted and underwent the resting-state functional magnetic resonance imaging(rs-f MRI)examination.The spontaneous cerebrum activity variations were inspected using the DC technology.The receiver operating characteristic(ROC)curve was implemented to distinguish the DC values of RVOs from HCs.The relationships between DC signal of definite regions of interest and the clinical characteristics in RVO group were evaluated by Pearson’s correlation analysis.RESULTS:RVOs showed notably higher DC signals in right superior parietal lobule,middle frontal gyrus and left precuneus,but decreased DC signals in left middle temporal gyrus and bilateral anterior cingulated(BAC)when comparing with HCs.The mean DC value of RVOs in the BAC were negatively correlated with the anxiety and depression scale.CONCLUSION:RVO is associated aberrant intrinsic brain activity patterns in several brain areas including painrelated as well as visual-related regions,which might assist to reveal the latent neural mechanisms.展开更多
基金Supported by National Natural Science Foundation of China (No.81760179 No.81360151)+2 种基金Natural Science Foundation of Jiangxi Province (No.20171BAB205046)Jiangxi Province Education Department Key Foundation (No. GJJ160033)Health Development Planning Commission Science Foundation of Jiangxi Province (No.20185118)
文摘AIM： To investigate the functional networks underlying the brain-activity changes of patients with high myopia using the voxel-wise degree centrality（DC） method.METHODS： In total, 38 patients with high myopia（HM）（17 males and 21 females）, whose binocular refractive diopter were-6.00 to-7.00 D, and 38 healthy controls（17 males and 21 females）, closely matched in age, sex, and education levels, participated in the study. Spontaneous brain activities were evaluated using the voxel-wise DC method. The receiver operating characteristic curve was measured to distinguish patients with HM from healthy controls. Correlation analysis was used to explore the relationship between the observed mean DC values of the different brain areas and the behavioral performance.RESULTS： Compared with healthy controls, HM patients had significantly decreased DC values in the right inferior frontal gyrus/insula, right middle frontal gyrus, and right supramarginal/inferior parietal lobule（P〈0.05）. In contrast, HM patients had significantly increased DC values in the right cerebellum posterior lobe, left precentral gyrus/postcentral gyrus, and right middle cingulate gyrus（P〈0.05）. However, no relationship was found between the observed mean DC values of the different brain areas and the behavioral performance（P〉0.05）.CONCLUSION： HM is associated with abnormalities in many brain regions, which may indicate the neural mechanisms of HM. The altered DC values may be used as a useful biomarker for the brain activity changes in HM patients.
文摘It is proved that if the degree of any non-linear irreducible character of a finite group G is a product of powers of two given distinct prime integers p and q, then G has an abelian Hall {p, q} subgroup H and an Abelian normal {p, q} complement A, and the centralizer in A of the Sylow p-subgroup of G is equal to the centralizer in A of the Sylow q-subgroup of G.
文摘AIM:To explore the intrinsic brain activity variations in retinal vein occlusion(RVO)subjects by using the voxel-wise degree centrality(DC)technique.METHODS:Twenty-one subjects with RVO and twentyone healthy controls(HCs)were enlisted and underwent the resting-state functional magnetic resonance imaging(rs-f MRI)examination.The spontaneous cerebrum activity variations were inspected using the DC technology.The receiver operating characteristic(ROC)curve was implemented to distinguish the DC values of RVOs from HCs.The relationships between DC signal of definite regions of interest and the clinical characteristics in RVO group were evaluated by Pearson’s correlation analysis.RESULTS:RVOs showed notably higher DC signals in right superior parietal lobule,middle frontal gyrus and left precuneus,but decreased DC signals in left middle temporal gyrus and bilateral anterior cingulated(BAC)when comparing with HCs.The mean DC value of RVOs in the BAC were negatively correlated with the anxiety and depression scale.CONCLUSION:RVO is associated aberrant intrinsic brain activity patterns in several brain areas including painrelated as well as visual-related regions,which might assist to reveal the latent neural mechanisms.
