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Enhancing Women's Well-being and Self-Confidence through Fragrance Cosmetics:Perceptions within Close and Broader Social Circles
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作者 Yang Fan Guo Miao +1 位作者 Zhou Ziyan Abriat Anne 《China Detergent & Cosmetics》 CAS 2024年第2期69-78,共10页
Mental and physical stress can affect people's self-confidence and happiness.The primary objective of this study is to develop an active fragrance that has been proved to have a positive effect on happiness and se... Mental and physical stress can affect people's self-confidence and happiness.The primary objective of this study is to develop an active fragrance that has been proved to have a positive effect on happiness and self-confidence based on the latest research results of aroma components and fragrance innovation.The active fragrance is applied to the cream formula to study the emotions it brings to the user and extend the research scope of the active emotion to the close and extensive social circle of users to see whether it can perceive it.This study provides a reference cosmetic solution for emotional regulating active fragrance. 展开更多
关键词 fragrance emotion CREAM social circle
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Causes and Countermeasures for Fragrance Diminishing of Rice Cultivar Daohuaxiang 2 in Heilongjiang Province 被引量:1
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作者 于清涛 李赞 刘乃新 《Agricultural Science & Technology》 CAS 2016年第10期2293-2296,共4页
High-quality fragrant rice Daohuaxiang 2 is a well-known variety in grain industry of Heilongjiang Province. However, its fragrance has weakened in recent years. In this paper, the causes for fragrance diminishing of ... High-quality fragrant rice Daohuaxiang 2 is a well-known variety in grain industry of Heilongjiang Province. However, its fragrance has weakened in recent years. In this paper, the causes for fragrance diminishing of Daohuaxiang 2 were discussed in depth. It was pointed out that variety degeneration, growth period influence, environmental factor influence, soil fertility influence and long drying time were the main causes for fragrance diminishing of Daohuaxiang 2. In addition, countermeasures for avoiding the fragrance diminishing were put forward. 展开更多
关键词 Daohuaxiang 2 fragrance Diminishing COUNTERMEASURES
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Synthesis of melamine-formaldehyde microcapsules containing oil-based fragrances via intermediate polyacrylate bridging layers 被引量:3
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作者 Yanping He Shunzhi Yao +5 位作者 JunzhengHao HongWang Linhua Zhu TianSi Yanlin Sun Jianhao Lin 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2019年第10期2574-2580,共7页
A general and versatile strategy to prepare melamine-formaldehyde(MF)microcapsules encapsulating oil-based fragrances by combining solvent evaporation and in situ polymerization was proposed in this work.The oil-based... A general and versatile strategy to prepare melamine-formaldehyde(MF)microcapsules encapsulating oil-based fragrances by combining solvent evaporation and in situ polymerization was proposed in this work.The oil-based fragrance was pre-encapsulated by an inner polyacrylate membrane via solvent evaporation,followed by in situ polymerization of MF precondensates as an outer shell.The polyacrylate membrane is used as an intermediate bridging layer to stabilize the oil-based fragrance,and to provide driving forces for in situ polymerization of MF precondensates through electrostatic attractions between carboxyl groups and ammonium ions.It was demonstrated that MF microcapsules containing clove oil were prepared successfully.The amount and the composition of the intermediate polyacrylate bridging layer were critical.Smooth and sphere-shaped MF-clove oil microcapsules were prepared when the weight ratio of polyacrylate to clove oil was over 60 wt%and the concentration of acrylic acid(AA)increased to 10 wt%in polyacrylate.In addition,MF microcapsules containing sunflower oil and hexyl salicylate were prepared by using this method.The work suggests that this new approach can be potentially used to encapsulate various core materials,tuning the shell properties of microcapsules such as thickness,mechanical strength and release properties. 展开更多
关键词 Melamine formaldehyde MICROCAPSULE OIL-BASED fragrance Particle Polymers Synthesis
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Human responses to flower fragrance of Lilium ‘Siberia’ and Rosa ‘Escimo’ 被引量:2
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作者 JIN Zi-lin LI Xia ZHANG Qi-xiang PAN Hui-tang AN Xue 《Forestry Studies in China》 CAS 2009年第3期185-189,共5页
The objective of our study was to lay a foundation for the effect of flower flagrance on human emotions and to provide a theory for the choice of indoor plants and the improvement of the olfactory environment. Specifi... The objective of our study was to lay a foundation for the effect of flower flagrance on human emotions and to provide a theory for the choice of indoor plants and the improvement of the olfactory environment. Specifically, our purpose was to study human physiological responses to flower fragrance of Lilium 'Siberia' and Rosa 'Escimo'. The participants were 31 college students. Blood pressure, pulse rate, finger temperature (FT) and galvanic skin response (GSR) were measured. The results show that the fragrance of Rosa 'Escimo' causes the diastolic pressure and pulse rate of the participants to reduce significantly. The average decrease was 0.37 kPa and 2.23 beats per minute, which indicates that sympathetic nervous activity increases, physiological arousal decreases and emotional alleviation occurs. Furthermore, the GSR of participants significantly increased by smelling the fragrance of Lilium 'Siberia', indicating that both sympathetic nervous activity and physiological arousal increased. But the data could not prove that flower fragrance stimulation has an effect on changes in systolic pressure and finger temperature. Some other factors, such as basic emotion and weather, may have an effect. 展开更多
关键词 Lilium 'Siberia' Rosa 'Escimo' flower fragrance PHYSIOLOGY
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Studies on Fragrance Raw Materials of α-Terpineol Analogues 被引量:1
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作者 Tang Shixiong, Liu Hong, Wang Changfeng, Cao Yurong, Liao Xiangmin and Wang Xiaolan (Department of Chemistry, Nankai University, Tianjin) 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1991年第4期212-220,共9页
Thirty four α-substituted or α, α-disubstituted-( 1-methylcyclohexen-4-yl )methanols and α-substituted or α,α-disubstituted-(4-methylcyclohexyl) methanols weresynthesized. Thirty two of them are new compounds. 1... Thirty four α-substituted or α, α-disubstituted-( 1-methylcyclohexen-4-yl )methanols and α-substituted or α,α-disubstituted-(4-methylcyclohexyl) methanols weresynthesized. Thirty two of them are new compounds. 1H NMR and IR spectra of allthe compounds were determined, MS spectra of some of them were obtained as well.The characteristic odors were evaluated.Keywords Fragrance raw materials,α-Terpineol analogues, Synthesis, Structuredetermination 展开更多
关键词 Studies on fragrance Raw Materials of ppm OH Terpineol Analogues
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Preliminary Measurement of Internal Organs of Congjiang Fragrance Pig and Huanjiang Fragrance Pig
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作者 Shen Xuelin Duan Yongbang +1 位作者 Zhang Yi Liu Peiqiong 《Animal Husbandry and Feed Science》 CAS 2014年第4期209-211,共3页
Fragrance pig is a famous miniature local breed in China,which is similar to human on the aspects of physical structure,anatomy,nutrition,metabolism and blood biochemical indicators. The internal organs of Congjiang f... Fragrance pig is a famous miniature local breed in China,which is similar to human on the aspects of physical structure,anatomy,nutrition,metabolism and blood biochemical indicators. The internal organs of Congjiang fragrance pig and Huanjiang fragrance pig with different month ages were weighed. The results showed that the proportion of stomach in body weight in Congjiang fragrance pig was higher than that in Min pig,Harbin white and Landrace,and the proportion of large intestine in body weight in Congjiang fragrance pig was also higher than that in ordinary pigs; the weights of heart,liver and kidney in 8- 10 months old Congjiang fragrance pig were similar to that in Chinese adults. This provided reference data for future in-depth development and utilization of fragrance pig. 展开更多
关键词 Congjiang fragrance pig Huanjiang fragrance pig Internal organs Weight measurement
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Studies on Silicon-Containing Fragrance Raw Materials( Ⅱ )——Syntheses and Odors of 4-Trimethylsilylcyclohex-3-enol and 4-Trimethylsilylcyclohexanol Derivatives
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作者 TANG Shi-xiong, XUE Jie-you, WU Jun-jun, CAO Yu-rongZHI Jin-fang WANG Xiao-lan (Department of Chemistry, Nankai University, Tianjin, 300071) 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1993年第2期121-126,共6页
1-Substituted- 4-trimethylsilylcyclohex- 3-enol and 1-substituted- 4-trimetnylsilyl-cyclohexanol, 4-trimethylsilylcyclohex-3-enol and 4-trimethylsilylcyclohexanol, and some of their esters and carbon counterparts were... 1-Substituted- 4-trimethylsilylcyclohex- 3-enol and 1-substituted- 4-trimetnylsilyl-cyclohexanol, 4-trimethylsilylcyclohex-3-enol and 4-trimethylsilylcyclohexanol, and some of their esters and carbon counterparts were synthesized. Structures of the nineteen new compounds were determined by 1H NMR, IR and MS. Their odors are evaluated. 展开更多
关键词 Silicon-containing fragrance raw materials SYNTHESES Odor evaluation
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Relationship between Ham Quality and Body Weight of Fragrance Pig
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作者 Shen Xuelin Duan Yongbang +3 位作者 Zhu Qiujin He Chengyuan Yang Yuanpiao Pan Shihua 《Animal Husbandry and Feed Science》 CAS 2014年第3期131-132,共2页
[ Objective ] The paper was to determine the weight range of fragrance pigs suitable for processing small ham. [ Method ] In terms of differences in sensory state and physical and chemical indicators of hams produced ... [ Objective ] The paper was to determine the weight range of fragrance pigs suitable for processing small ham. [ Method ] In terms of differences in sensory state and physical and chemical indicators of hams produced by fragrance pigs with different weights, 29 fragrance pigs at five weight grades were chosen and processed in accordance with Chinese ham processing methods. The products were evaluated by sense, and their salt and moisture contents were also measured. [Result] The fragTance pigs less than 30 kg were not suitable for making Chinese ham, while the fragrance pigs weighed 32 -45 kg could be made into the ham with prominent flavor, beautiful appearance, good color, moderate taste, and suitable moisture content, of which the pigs weighed 40 -45 kg were the best materials for processing small ham. [ Conclusion] The study provided scientific basis for industrial development of fragrance pig. 展开更多
关键词 fragrance pig Chinese ham Raw material SCREENING Food processing
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Growth Development and Reproductive Performance of Congjiang Fragrance Pig
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作者 Shen Xuelin Duan Yongbang +1 位作者 Yang Xiujiang Wei Shengquan 《Animal Husbandry and Feed Science》 CAS 2014年第5期269-270,275,共3页
[Objective] The paper was to determine whether the germplasm resources of Congjiang fragrance pig had changed over the past 30 years. [Method]The growth development and reproductive performance of 100 pigs from six to... [Objective] The paper was to determine whether the germplasm resources of Congjiang fragrance pig had changed over the past 30 years. [Method]The growth development and reproductive performance of 100 pigs from six towns in central fragrance pig producing area and Congjiang fragrance pig stock seed farm were measured,and further compared with the data in Guizhou Livestock and Poultry Breeds 1986. [Result]The growth and development status was basically consistent,and the average litter size was at a downward trend: the first litter decreased by 26. 2%; the second litter decreased by 7. 0%; the third litter decreased by8. 55%. [Conclusion] The study laid the foundation for vigorous promotion of Congjiang fragrance pig in industrial development process,acceleration of breeding pace,gradual updating of farming breeds by farmers and improvement of production efficiency of fragrance pig. 展开更多
关键词 Congjiang fragrance pig Growth development Reproductive performance MEASUREMENT
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Genetic Relationship of Fragrance Pigs
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作者 Shen Xuelin Duan Yongbang +3 位作者 Yao Shaokuan Zhang Qin Liu Peiqiong Zhang Yun 《Animal Husbandry and Feed Science》 CAS 2014年第6期316-318,共3页
[ Objective] The paper was to study the genetic background of four unique types of fragrance pigs in China. [ Method ] Using 27 pairs of micmsatellite loci jointly recommended by Food and Agricultural Organization (... [ Objective] The paper was to study the genetic background of four unique types of fragrance pigs in China. [ Method ] Using 27 pairs of micmsatellite loci jointly recommended by Food and Agricultural Organization (FAO) and International Society for Animal Genetics (ISAG), we detected the genotypes of 200 fragrance individuals belonging to four types (Jiuyang fragrance pig, Jianbai fragrance pig, Cangjiang fragrance pig and Huangjiang fragrance pig), and analyzed their inter-and intra-breed genetic variations. Clustering analysis was also conducted using neighbor-joining (NJ) method and unweighted pair-group method with arithmetic mean (UPGMA). [ Result] The genetic relationship between Congiiang fragrance pig and Huangjiang fragrance pig was the closest, followed by the ge- netic relationship between Jiuyang fragrance pig and Jianbai fragrance pig; the genetic distance between Jianbai fragrance pig and Huangjiang fragrance pig was the farthest, which was consistent with their geographic distribution, ecological environment and body physical characteristics. Clustering resuhs showed that Jiuyang fragrance pig and Jianbai fragrance pig clustered into one class, while Congjiang fragrance pig and Huangjiang fragrance pig clustered into another class. [ Conclu- sion] The study laid the foundation for quantitative trait loci positioning of good genes of these breeds and implementation of genetic marker-assisted selection. 展开更多
关键词 fragrance pig Microsatellite markers Genetic relationship Clustering analysis
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Application of Ethylparaben in Quality Control of Favoring Agents and Fragrances Used for Cigarette Production
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作者 Lizhi DANG Rui YUE +2 位作者 Wenhan DONG Genhua YANG Yanqing DUAN 《Agricultural Biotechnology》 CAS 2017年第2期58-60,共3页
This study was conducted to evaluate the antimierobial activity of ethylparaben (ethyl para-hydroxybenzoate) in flavoring agents and fragrances used tot cigarette production. In brief, different levels of ethylparab... This study was conducted to evaluate the antimierobial activity of ethylparaben (ethyl para-hydroxybenzoate) in flavoring agents and fragrances used tot cigarette production. In brief, different levels of ethylparaben were added to Ziyun and Ruanzhen fragrance concentrates, and fermented with or without the additiorl of extra microbial strains. The aroma components in the fermented samples were detected via gas chromatography-mass spectrometry (GC/MS) assay. The results showed that ethylparaben had good antimicrobial activity on the microorganism in Ziyun and Ruanzhen fragrances, and as it significantly inhibited the growth of Sac- charomyces sp. Aeetobacter sp. , Agrobacterium sp. and Bacillus sp. , with an inhibition rate of 53%. Under natural fermentation condition, 91. 885% of the micro- organisms were inhibited by adding 0. 1 g/kg ethylparaben, 97.69% were inhibited by adding 0.3 g/kg ethylparaben, and 100% were inhibited by adding 0.5 g/kg ethylparaben. Moreover, the addition of ethylparaben had no obvious influence on the aroma components of the favoring agents and fragrances. So, it carl be used as a preservative for the quality control of favoring agents and fragrances for cigarette production. 展开更多
关键词 Flavoring agents and fragrances Cigarette production ETHYLPARABEN antimicrobial activity Quality control
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Volatile metabolome and transcriptome reveal fragrance release rhythm and molecular mechanisms of Rosa yangii
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作者 ZHOU Li-jun HUANG Run-huan +7 位作者 LIU Ting-han LIU Wei-chao CHEN Yun-yi LÜPei-feng LUO Le PAN Hui-tang YU Chao ZHANG Qi-xiang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2023年第7期2111-2125,共15页
Rose is a highly significant ornamental plant with substantial edible and medicinal value,cultivated worldwide primarily for perfume production.Recently,Rosa yangii,a new species found in northwestern Yunnan,China,has... Rose is a highly significant ornamental plant with substantial edible and medicinal value,cultivated worldwide primarily for perfume production.Recently,Rosa yangii,a new species found in northwestern Yunnan,China,has drawn attention due to its strong sweet scented flowers.In this study,the floral components of R.yangii were extracted at different flowering stages using solid phase micro extraction(SPME)and analyzed through gas chromatography-mass spectrometry(GC-MS).A total of 131 volatile organic compounds(VOCs)were detected from R.yangii,including 69 odor compounds.The production and release of floral VOCs were the highest during the initial-open stage,making it the most suitable time for harvesting as a significant number of floral components were synthesized and preserved.The analysis of the odor activity values(OAV)highlighted several key aromatic ingredients of R.yangii,such as eugenol,methyleugenol,benzeneacetaldehyde and phenylethylalcohol,heptanal,decanal,(E)-2-hexen-1-yl acetate,caryophyllene,and others.Metabolome and time-order gene co-expression networks(TO-GCN)revealed that VOCs and benzenoids/phenylpropanoids,along with associated genes,played a pivotal role in the overall floral regulatory network of R.yangii.MYB and bHLH were identified as the essential regulatory factors governing the regulation of eugenol synthase(EGS)and isoeugenol synthase(IGS),consequently influencing the sweet scent of R.yangii.The findings of this study provide a scientific foundation for enhancing fragrance through molecular breeding of ornamental plants.Furthermore,the study facilitated the development and utilization of this new plant’s essential oil material in various industries,including food storage,aromatherapy,cosmetic,and perfumery. 展开更多
关键词 rose sweet fragrance SPME-GC-MS aroma VOCs TO-GCN
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Application of Silica Aerogel Carrier via Supercritical Drying for Fragrance Controlled-release
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作者 黄龙 ZHANG Jing +6 位作者 PANG Denghong XIONG Man BIE Xuan DONG Yawei WANG Ben 罗诚浩 黄荣华 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2023年第4期807-814,共8页
Silica aerogel with different hydrophilicities were prepared from tetramethoxysilane,Methymethoxysilane,tetramethoxysilane-propyltrimethoxysilane,or tetramethoxysilane-phenyltrimethoxysilane mixtures via supercritical... Silica aerogel with different hydrophilicities were prepared from tetramethoxysilane,Methymethoxysilane,tetramethoxysilane-propyltrimethoxysilane,or tetramethoxysilane-phenyltrimethoxysilane mixtures via supercritical drying process(labelled as TMOS-AG Me-TMOS-AG,Pr-TMOS-AG,or Ph-TMOS-AG,respectively).Three fragrances,including geraniol,ethyl vanillin,and menthol,were loaded to TMOS-AG.The thermal analysis confirmed all loading fragrances are stable until over 200℃.And among all fragrances,geraniol presented the maximum loading contents(L_(m)).Concentration dependences indicated the geraniol was mono layer absorbed.Py-GC/MS of geraniol in TMOS-AG under both N_(2)and mimic air atmosphere(90%N_(2)and 10%O_(2))confirmed that loaded geraniol could be thermally controlled-released beginning at 200℃.As N_(2)absorption confirmed,even absorption/desorption equilibrium constant(k)was determined mainly by hydrophilicity of silica aerogels,and the maximum loading contents(L_(m))were influenced more by the pore size.Due to mono layered absorption,bigger pores usually give less specific areas and less absorbing sites for geraniol,and then present lower L_(m). 展开更多
关键词 silica aerogel fragrance CONTROLLED-RELEASE
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Intra-breed Genetic Variation of Fragrance Pigs Detected by Microsatellite Markers
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作者 Shen Xuelin Duan Yongbang +2 位作者 Yao Shaokuan Zhang Qin Liu Peiqiong 《Animal Husbandry and Feed Science》 CAS 2015年第1期7-8,11,共3页
[Objective] The genetic background of four types of fragrance pigs was studied using microsatellite molecular markers,in order to fully understand the genetic resources of miniature pigs in China.[Method] Using 27 pai... [Objective] The genetic background of four types of fragrance pigs was studied using microsatellite molecular markers,in order to fully understand the genetic resources of miniature pigs in China.[Method] Using 27 pairs of microsatellite loci jointly recommended by Food and Agricultural Organization(FAO)and International Society for Animal Genetics(ISAG),we detected the genotypes of 200 fragrance individuals belonging to four types(Jiuyang fragrance pig,Jianbai fragrance pig,Congjiang fragrance pig and Huanjiang fragrance pig),and analyzed their Inter-and intra-breed genetic variations.[Result]The 23 loci detected in the test were high polymorphic;the mean heterozygosity(H) of Jiuyang fragrance pig,Jianbai fragrance pig,Congjiang fragrance pig and Huanjiang fragrance pig were 0.683 6,0.667 9,0.697 3 and 0.702 2,and their mean polymorphism information contents(PIC) were 0.6263,0.6063,0.6420 and 0.6415,respectively.[Conclusion]Four types of fragrance pigs detected in the test all had high intra-breed genetic variability. 展开更多
关键词 fragrance pig Microsatellite markers Genetic diversity
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The Balance Between the Transmitted and the Perceived Image of Luxury Fragrance Brands
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作者 Monica Diaz-Bustamante Sonia Carcelen Maria Puelles 《Journal of Modern Accounting and Auditing》 2015年第10期499-514,共16页
The luxury market has experienced considerable growth over recent years, being one of the sectors that have been the most resistant to the current economic recession. Selective fragrances make up one of the primary ca... The luxury market has experienced considerable growth over recent years, being one of the sectors that have been the most resistant to the current economic recession. Selective fragrances make up one of the primary categories of the so-called accessible luxury consumed by a middle class that is seeking to approach the upper classes by copying their lifestyle. Despite the importance of this market, there is relatively little literature existing in regards to the study of the image of luxury brands due to the complexity of the luxury phenomenon. This article presents the results of an initial qualitative study conducted on focus groups of luxury fragrance consumers, making it possible to identify the types of attributes to be considered when studying the brand image of said luxury products. Subsequently, a quantitative study was conducted in order to determine the perceived image of the principle luxury fragrance brands by consumers. Thanks to this study, it has been possible to determine the typical profile of each of the analyzed brands so that a subsequent comparison may be made with the advertising created by said brands in order to verify whether or not the image projected in their advertising corresponds with the perceived image of their target audience. 展开更多
关键词 brand image LUXURY fragranceS ADVERTISING PERCEPTIONS
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A Brief Analysis of the Influence of China-Us Trade Friction on China’s Fragrance and Flavor Industry
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作者 Zhang Jiahao Mu Min +3 位作者 Liu Hua Liang Yanhui Zhang Peng Liu Lu 《China Detergent & Cosmetics》 2020年第1期31-35,共5页
Trade friction between China and US have escalated,commodities involved in China-US trade is being affected.China is important import and export market for fragrance and flavor.The United States is the third largest i... Trade friction between China and US have escalated,commodities involved in China-US trade is being affected.China is important import and export market for fragrance and flavor.The United States is the third largest importer and the largest exporter of China’s fragrance and flavor commodities.This round of tariff increasing has important impact on China’s fragrance and flavor trade.In the review,development of China’s fragrance and flavor industry and the situation of their imports and exports,especially trade between China and US,are briefly introduced;focusing on the tariff increasing of fragrance and flavor products between the two countries,the impact of trade friction to the industry is anticipated. 展开更多
关键词 fragrance and flavor trade friction international competition
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Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models 被引量:4
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作者 OH Jae-Young RYU Bo-Mi +3 位作者 YANG Hye-Won KIM Eun-A LEE Jung-Suck JEON You-Jin 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2019年第3期909-917,共9页
Oxidative hair dyes containingρ-phenylenediamine(PPD)are reported to induce an allergic reaction by promoting oxidative stress when absorbed through the skin.Despite the associated risk,these hair dyes remain popular... Oxidative hair dyes containingρ-phenylenediamine(PPD)are reported to induce an allergic reaction by promoting oxidative stress when absorbed through the skin.Despite the associated risk,these hair dyes remain popular owing to their convenience and sharpness of color.This makes it important to minimize the cytotoxicity and oxidative stress induced by PPD-containing hair dyes.Ecklonia cava extract has been evaluated in different studies for its protective effects against external stress in fibroblasts and keratinocytes.Our study was aimed at using in-vitro and in-vivo models to investigate the extract’s effects on cytotoxicity of and oxidative stress induced by PPD-containing hair dyes.Analysis of CIEL*a*b*Color space was first used to determine the range of E.cava extract that would not interfere with the coloring ability of the dye upon addition.Subsequently,the set ranges of E.cava extract(5% and 7%)were added to the hair dye and their toxicity assessed by evaluating the viability of fibroblasts and keratinocytes.The effects on developmental phenotypes and induction of oxidative stress by hair dye were evaluated and compared with those of hair dyes containing different contents of E.cava extract using an in-vivo zebrafish model.Our results showed that E.cava extract in hair dye could significantly decrease the cytotoxicity and levels of oxidative stress caused by hair dyes containing PPD in both in-vitro and in-vivo models.These results suggest that the addition of 7% E.cava extract to 250μg/mL hair dye does not interfere with the coloring ability of the dye while showing significant protective eff ects against the hair dye.The study proposes that the use of E.cava extract as an adduct to hair dyes containing PPD reduces the cytotoxicity and oxidative stress induced by these hair dyes. 展开更多
关键词 HAIR dye Ecklonia cava CYTOTOXICITY oxidative stress in-vitro and in-vivo MODELS
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In-vitro and In-vivo Anti-trypanosomal Activity of Terminalia chebula Retz Dried Fruits 被引量:1
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作者 Shaba Peter Sahab Dey +1 位作者 Singh Raj Kumar Chaudary Paulad 《Journal of Pharmacy and Pharmacology》 2016年第9期492-500,共9页
African trypanosomosis had caused lots of havocs to both humans and animals over a century with successes and failure in curtailing it. This study was aimed at screening medicinal plant, Terminalia chebula dried fruit... African trypanosomosis had caused lots of havocs to both humans and animals over a century with successes and failure in curtailing it. This study was aimed at screening medicinal plant, Terminalia chebula dried fruits against Trypanosoma evansi for trypanocidal activity. Twenty grams of powdered Terminalia chebula dried fruits was cold extracted with methanol. Obtained MPE (methanolic plant extract) was in vitro tested against Trypanosoma brucei (1 × 10^6 trypanosomes/mL of the medium in each ELISA plate wells) at concentrations (250~1,000 μg/mL) on Vero cells grown in DMEM (Debecco's Modified Eagle Medium) in appropriate conditions for trypanocidal activity. In-vitro cytotoxicity test of MPE of Terminalia chebula was conducted on Vero cells grown in DMEM. In-vivo assay for trypanocidal activity, each mouse was inoculated with 1 × 10^4/mL of trypanosomes and treated (48 h post inoculation) with MPE of Terminalia chebula at concentrations (12.5, 25, 50, 100 and 200 mg/kg body weight) were administered at dose rate of 100 BL per mouse via intraperitoneal route to different groups of mice, 6 mice per concentration. In-vitro cytotoxicity test was done on Veto cells at concentrations (1.58~100 μg/mL) of MPE of Terminalia chebula. Results of in-vitro trypanocidal activity varied from immobilization, reduction and to the killing of the trypanosomes. At 250 μg/mL ofMPE ofTerminalia chebula dried fruits, there was significant trypanocidal activity at 4 h of incubation and trypanosomes were not detected in corresponding ELISA plate wells at 5 h of incubation, which was statistically equivalent to reference drug, diminazine aceturate (50 μL/mL) at 4 h of incubation. Results of in-vivo trypanocidal activity revealed that at concentrations (l 2.5~25 mg/kg body weight) of MPE of Terrninalia chebula, mice in these groups survived for 6 days. While at 50 and 100 to 200 mg/kg body weight, mice in these groups survived up to 7 and 8 days, respectively. In-vitro cytotoxicity test showed that all concentrations of MPE of Terminalia chenula and diminazine aceturate were cytotoxic to cells except at 1.56 μL/mL and 6.25 μL/mL. In conclusion, MPE of Terminalia chebula dried fruits possessed trypanocidal compounds. Further study (bioassay-guided purification) is required to know the full potential of Terrninalia chebula as future trypanocide candidate. 展开更多
关键词 Terminalia chebula dried fruits in-vitro and in-vivo trypanocidal activity in-vitro cytotoxicity.
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Position Verification of the RADPOS 4-D <i>In-Vivo</i>Dosimetry System
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作者 Ryosuke Kohno Hidenori Yamaguchi +8 位作者 Kana Motegi Fumiya Tanaka Tsunemichi Akita Yuki Nagata Kenji Hotta Tomoko Miyagishi Shie Nishioka Takeshi Dohmae Tetsuo Akimoto 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2015年第4期318-325,共8页
The accuracy of the position measurements obtained by the radiation positioning system (RADPOS) was evaluated under static and dynamic conditions. In the static verifications, the RADPOS was fixed to the treatment cou... The accuracy of the position measurements obtained by the radiation positioning system (RADPOS) was evaluated under static and dynamic conditions. In the static verifications, the RADPOS was fixed to the treatment couch in a photon treatment room and a proton treatment room, and was translocated with the treatment couch in x, y and z directions. Because the presence of magnetic and/or electrically conductive materials can cause a systematic shift in the measured position by distorting the RADPOS transmitted field, the effect of metals on the performance of the positioning system was also investigated. Dynamic verification was performed using the couch drive and a dynamic anthropomorphic thorax phantom. We thus confirmed the utility of RADPOS as a position sensor to perform in vivo dosimetry. 展开更多
关键词 RADPOS MOSFET in-vivo DOSIMETRY Position Sensor Photon THERAPY Proton Beam THERAPY
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Mathematical Modelling of In-Vivo Dynamics of HIV Subject to the Influence of the CD8+ T-Cells
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作者 Purity M. Ngina Rachel Waema Mbogo Livingstone S. Luboobi 《Applied Mathematics》 2017年第8期1153-1179,共27页
There have been many mathematical models aimed at analysing the in-vivo dynamics of HIV. However, in most cases the attention has been on the interaction between the HIV virions and the CD4+ T-cells. This paper brings... There have been many mathematical models aimed at analysing the in-vivo dynamics of HIV. However, in most cases the attention has been on the interaction between the HIV virions and the CD4+ T-cells. This paper brings in the intervention of the CD8+ T-cells in seeking, destroying, and killing the infected CD4+ T-cells during early stages of infection. The paper presents and analyses a five-component in-vivo model and applies the results in investigating the in-vivo dynamics of HIV in presence of the CD8+ T-cells. We prove the positivity and the boundedness of the model solutions. In addition, we show that the solutions are biologically meaningful. Both the endemic and virions- free equilibria are determined and their stability investigated. In addition, the basic reproductive number is derived by the next generation matrix method. We prove that the virions-free equilibrium state is locally asymptotically stable if and only if R0 < 1 and unstable otherwise. The results show that at acute infection the CD8+ T-cells play a paramount role in reducing HIV viral replication. We also observe that the model exhibits backward and trans-critical bifurcation for some set of parameters for R0 . This is a clear indication that having R0 is not sufficient condition for virions depletion. 展开更多
关键词 HIV Endemic EQUILIBRIUM Global Stability in-vivo Disease-Free EQUILIBRIUM Basic Reproductive Number Backward Bifurcation
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