Prevalence and characterization of plasmid-mediated blaESBL with their genetic environment in Escherichia coli and Klebsiella pneumoniae in patients with pneumonia

Background The extended spectrum 13-1actamase （ESBL）-producing Escherichia coil （E. coh） and Klebsiella pneumoniae （K. pneumoniae） are the major pathogens causing pneumonia and have a significant impact on the clinical course. Limited data exist on molecular characterization of ESBL-producing E. coli and K. pneumoniae that cause pneumonia. The aim of this study was to investigate the comprehensive multilevel characteristics of E. coil and K. pneumoniae causing pneumonia in China for the first time.