BACKGROUND Synchronous liver metastasis(SLM)is a significant contributor to morbidity in colorectal cancer(CRC).There are no effective predictive device integration algorithms to predict adverse SLM events during the ...BACKGROUND Synchronous liver metastasis(SLM)is a significant contributor to morbidity in colorectal cancer(CRC).There are no effective predictive device integration algorithms to predict adverse SLM events during the diagnosis of CRC.AIM To explore the risk factors for SLM in CRC and construct a visual prediction model based on gray-level co-occurrence matrix(GLCM)features collected from magnetic resonance imaging(MRI).METHODS Our study retrospectively enrolled 392 patients with CRC from Yichang Central People’s Hospital from January 2015 to May 2023.Patients were randomly divided into a training and validation group(3:7).The clinical parameters and GLCM features extracted from MRI were included as candidate variables.The prediction model was constructed using a generalized linear regression model,random forest model(RFM),and artificial neural network model.Receiver operating characteristic curves and decision curves were used to evaluate the prediction model.RESULTS Among the 392 patients,48 had SLM(12.24%).We obtained fourteen GLCM imaging data for variable screening of SLM prediction models.Inverse difference,mean sum,sum entropy,sum variance,sum of squares,energy,and difference variance were listed as candidate variables,and the prediction efficiency(area under the curve)of the subsequent RFM in the training set and internal validation set was 0.917[95%confidence interval(95%CI):0.866-0.968]and 0.09(95%CI:0.858-0.960),respectively.CONCLUSION A predictive model combining GLCM image features with machine learning can predict SLM in CRC.This model can assist clinicians in making timely and personalized clinical decisions.展开更多
AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix metho...AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix method and trained a Bayesian model based on these textures. The receiver operating characteristic(ROC) curve was used to estimate the sensitivity and specificity of the Bayesian model.RESULTS: A total of 1000 eyes fundus images from diabetic patients in which 298 eyes were diagnosed as DR by two ophthalmologists. The Bayesian model was trained using four extracted textures including contrast, entropy, angular second moment and correlation using a training dataset. The Bayesian model achieved a sensitivity of 0.949 and a specificity of 0.928 in the validation dataset. The area under the ROC curve was 0.938, and the 10-fold cross validation method showed that the average accuracy rate is 93.5%.CONCLUSION: Textures extracted by grey level cooccurrence can be useful information for DR diagnosis, and a trained Bayesian model based on these textures can be an effective tool for DR screening among diabetic patients.展开更多
In recent years,binary image steganography has developed so rapidly that the research of binary image steganalysis becomes more important for information security.In most state-of-the-art binary image steganographic s...In recent years,binary image steganography has developed so rapidly that the research of binary image steganalysis becomes more important for information security.In most state-of-the-art binary image steganographic schemes,they always find out the flippable pixels to minimize the embedding distortions.For this reason,the stego images generated by the previous schemes maintain visual quality and it is hard for steganalyzer to capture the embedding trace in spacial domain.However,the distortion maps can be calculated for cover and stego images and the difference between them is significant.In this paper,a novel binary image steganalytic scheme is proposed,which is based on distortion level co-occurrence matrix.The proposed scheme first generates the corresponding distortion maps for cover and stego images.Then the co-occurrence matrix is constructed on the distortion level maps to represent the features of cover and stego images.Finally,support vector machine,based on the gaussian kernel,is used to classify the features.Compared with the prior steganalytic methods,experimental results demonstrate that the proposed scheme can effectively detect stego images.展开更多
Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation...Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation of experienced pathologists. However, it is difficult to separate the favor benign from borderline types. Thus, this paper presents a classification approach based on 3D nuclei model to classify favor benign and borderline types of follicular thyroid adenoma (FTA) in cytological specimens. The proposed method utilized 3D gray level co-occurrence matrix (GLCM) and random forest classifier. It was applied to 22 data sets of FN images. Furthermore, the use of 3D GLCM was compared with 2D GLCM to evaluate the classification results. From experimental results, the proposed system achieved 95.45% of the classification. The use of 3D GLCM was better than 2D GLCM according to the accuracy of classification. Consequently, the proposed method probably helps a pathologist as a prescreening tool.展开更多
A leukocyte recognition system, as part of a differential blood counter system, is very important in hematology field. In this paper, the propose system aims to automatically classify the white blood cells (leukocytes...A leukocyte recognition system, as part of a differential blood counter system, is very important in hematology field. In this paper, the propose system aims to automatically classify the white blood cells (leukocytes) on a given microscopic image. The classifications of leukocytes are performed based on the combination of color and texture features of the blood cell images. The developed system classifies the leukocytes in one of the five categories (neutrophils, eosinophils, basophils, lymphocytes, and monocytes). In the preprocessing stage, the system starts with converting the microscopic images from Red Green Blue (RGB) color space to Hue Saturation Value (HSV) color space. Next, the system splits the Hue and Saturation features from the Value feature. For both Hue and Saturation features, the system processes their color information using the Feature Selection method and the Window Cropping method;while the Value feature is processed by its texture information using the Co-occurrence matrix method. The final recognition stage is performed using the Euclidean distance method. The combination of the Feature Selection and Co-occurrence Matrix methods gives the best overall recognition accuracies for classifying leukocyte images.展开更多
Performance index mance evaluation, and is the is the standard of perfor- foundation of both perfor- mance analysis and optimal design for the parallel manipulator. Seeking the suitable kinematic indices is always an ...Performance index mance evaluation, and is the is the standard of perfor- foundation of both perfor- mance analysis and optimal design for the parallel manipulator. Seeking the suitable kinematic indices is always an important and challenging issue for the parallel manipulator. So far, there are extensive studies in this field, but few existing indices can meet all the requirements, such as simple, intuitive, and universal. To solve this problem, the matrix orthogonal degree is adopted, and generalized transmission indices that can evaluate motion/force trans- missibility of fully parallel manipulators are proposed. Transmission performance analysis of typical branches, end effectors, and parallel manipulators is given to illus- trate proposed indices and analysis methodology. Simula- tion and analysis results reveal that proposed transmission indices possess significant advantages, such as normalized finite （ranging from 0 to l）, dimensionally homogeneous, frame-free, intuitive and easy to calculate. Besides, pro- posed indices well indicate the good transmission region and relativity to the singularity with better resolution than the traditional local conditioning index, and provide a novel tool for kinematic analysis and optimal design of fully parallel manipulators.展开更多
The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material ...The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material design. At present,the quantitative characterization methods mainly rely on the microstructure characterization of shape, size, distribution,and volume fraction, which related to the mechanical properties. These traditional methods have been applied for several decades and the subjectivity of human factors induces unavoidable errors. In this paper, we try to bypass the traditional operations and identify the relationship between the microstructures and the material properties by the texture of image itself directly. The statistical approach is based on gray level Co-occurrence matrix（GLCM）, allowing an objective and repeatable study on material microstructures. We first present how to identify GLCM with the optimal parameters, and then apply the method on three systems with different microstructures. The results show that GLCM can reveal the interface information and microstructures complexity with less human impact. Naturally, there is a good correlation between GLCM and the mechanical properties.展开更多
A novel topological index W F is defined by the matrices X,W and L as W F=XWL.The topological index WF based on the distance-related matrix of molecular graphs is used to code the structural environment of each atom...A novel topological index W F is defined by the matrices X,W and L as W F=XWL.The topological index WF based on the distance-related matrix of molecular graphs is used to code the structural environment of each atom-type in a molecular graph.Good QSPR models have been obtained for standard formation enthalpy of methyl halides.The result indicates that the idea of using multiple matrices to define the distance-related matrix topological index is valid.展开更多
Data is humongous today because of the extensive use of World WideWeb, Social Media and Intelligent Systems. This data can be very important anduseful if it is harnessed carefully and correctly. Useful information can...Data is humongous today because of the extensive use of World WideWeb, Social Media and Intelligent Systems. This data can be very important anduseful if it is harnessed carefully and correctly. Useful information can beextracted from this massive data using the Data Mining process. The informationextracted can be used to make vital decisions in various industries. Clustering is avery popular Data Mining method which divides the data points into differentgroups such that all similar data points form a part of the same group. Clusteringmethods are of various types. Many parameters and indexes exist for the evaluationand comparison of these methods. In this paper, we have compared partitioningbased methods K-Means, Fuzzy C-Means (FCM), Partitioning AroundMedoids (PAM) and Clustering Large Application (CLARA) on secure perturbeddata. Comparison and identification has been done for the method which performsbetter for analyzing the data perturbed using Extended NMF on the basis of thevalues of various indexes like Dunn Index, Silhouette Index, Xie-Beni Indexand Davies-Bouldin Index.展开更多
文摘BACKGROUND Synchronous liver metastasis(SLM)is a significant contributor to morbidity in colorectal cancer(CRC).There are no effective predictive device integration algorithms to predict adverse SLM events during the diagnosis of CRC.AIM To explore the risk factors for SLM in CRC and construct a visual prediction model based on gray-level co-occurrence matrix(GLCM)features collected from magnetic resonance imaging(MRI).METHODS Our study retrospectively enrolled 392 patients with CRC from Yichang Central People’s Hospital from January 2015 to May 2023.Patients were randomly divided into a training and validation group(3:7).The clinical parameters and GLCM features extracted from MRI were included as candidate variables.The prediction model was constructed using a generalized linear regression model,random forest model(RFM),and artificial neural network model.Receiver operating characteristic curves and decision curves were used to evaluate the prediction model.RESULTS Among the 392 patients,48 had SLM(12.24%).We obtained fourteen GLCM imaging data for variable screening of SLM prediction models.Inverse difference,mean sum,sum entropy,sum variance,sum of squares,energy,and difference variance were listed as candidate variables,and the prediction efficiency(area under the curve)of the subsequent RFM in the training set and internal validation set was 0.917[95%confidence interval(95%CI):0.866-0.968]and 0.09(95%CI:0.858-0.960),respectively.CONCLUSION A predictive model combining GLCM image features with machine learning can predict SLM in CRC.This model can assist clinicians in making timely and personalized clinical decisions.
基金Supported by the Priming Scientific Research Foundation for the Junior Researcher in Beijing Tongren Hospital,Capital Medical University
文摘AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix method and trained a Bayesian model based on these textures. The receiver operating characteristic(ROC) curve was used to estimate the sensitivity and specificity of the Bayesian model.RESULTS: A total of 1000 eyes fundus images from diabetic patients in which 298 eyes were diagnosed as DR by two ophthalmologists. The Bayesian model was trained using four extracted textures including contrast, entropy, angular second moment and correlation using a training dataset. The Bayesian model achieved a sensitivity of 0.949 and a specificity of 0.928 in the validation dataset. The area under the ROC curve was 0.938, and the 10-fold cross validation method showed that the average accuracy rate is 93.5%.CONCLUSION: Textures extracted by grey level cooccurrence can be useful information for DR diagnosis, and a trained Bayesian model based on these textures can be an effective tool for DR screening among diabetic patients.
基金This work is supported by the National Natural Science Foundation of China(No.U1736118)the Natural Science Foundation of Guangdong(No.2016A030313350)+3 种基金the Special Funds for Science and Technology Development of Guangdong(No.2016KZ010103)the Key Project of Scientific Research Plan of Guangzhou(No.201804020068)the Fundamental Research Funds for the Central Universities(No.16lgjc83 and No.17lgjc45)the Science and Technology Planning Project of Guangdong Province(Grant No.2017A040405051).
文摘In recent years,binary image steganography has developed so rapidly that the research of binary image steganalysis becomes more important for information security.In most state-of-the-art binary image steganographic schemes,they always find out the flippable pixels to minimize the embedding distortions.For this reason,the stego images generated by the previous schemes maintain visual quality and it is hard for steganalyzer to capture the embedding trace in spacial domain.However,the distortion maps can be calculated for cover and stego images and the difference between them is significant.In this paper,a novel binary image steganalytic scheme is proposed,which is based on distortion level co-occurrence matrix.The proposed scheme first generates the corresponding distortion maps for cover and stego images.Then the co-occurrence matrix is constructed on the distortion level maps to represent the features of cover and stego images.Finally,support vector machine,based on the gaussian kernel,is used to classify the features.Compared with the prior steganalytic methods,experimental results demonstrate that the proposed scheme can effectively detect stego images.
文摘Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation of experienced pathologists. However, it is difficult to separate the favor benign from borderline types. Thus, this paper presents a classification approach based on 3D nuclei model to classify favor benign and borderline types of follicular thyroid adenoma (FTA) in cytological specimens. The proposed method utilized 3D gray level co-occurrence matrix (GLCM) and random forest classifier. It was applied to 22 data sets of FN images. Furthermore, the use of 3D GLCM was compared with 2D GLCM to evaluate the classification results. From experimental results, the proposed system achieved 95.45% of the classification. The use of 3D GLCM was better than 2D GLCM according to the accuracy of classification. Consequently, the proposed method probably helps a pathologist as a prescreening tool.
文摘A leukocyte recognition system, as part of a differential blood counter system, is very important in hematology field. In this paper, the propose system aims to automatically classify the white blood cells (leukocytes) on a given microscopic image. The classifications of leukocytes are performed based on the combination of color and texture features of the blood cell images. The developed system classifies the leukocytes in one of the five categories (neutrophils, eosinophils, basophils, lymphocytes, and monocytes). In the preprocessing stage, the system starts with converting the microscopic images from Red Green Blue (RGB) color space to Hue Saturation Value (HSV) color space. Next, the system splits the Hue and Saturation features from the Value feature. For both Hue and Saturation features, the system processes their color information using the Feature Selection method and the Window Cropping method;while the Value feature is processed by its texture information using the Co-occurrence matrix method. The final recognition stage is performed using the Euclidean distance method. The combination of the Feature Selection and Co-occurrence Matrix methods gives the best overall recognition accuracies for classifying leukocyte images.
基金Supported by National Natural Science Foundation of China(Grant Nos.51575292,51475252,91648107)National Key Technology Research and Development Program of China(Grant No.2105BAF19B00)National Science and Technology Major Project of China(Grant No.2016ZX04004004)
文摘Performance index mance evaluation, and is the is the standard of perfor- foundation of both perfor- mance analysis and optimal design for the parallel manipulator. Seeking the suitable kinematic indices is always an important and challenging issue for the parallel manipulator. So far, there are extensive studies in this field, but few existing indices can meet all the requirements, such as simple, intuitive, and universal. To solve this problem, the matrix orthogonal degree is adopted, and generalized transmission indices that can evaluate motion/force trans- missibility of fully parallel manipulators are proposed. Transmission performance analysis of typical branches, end effectors, and parallel manipulators is given to illus- trate proposed indices and analysis methodology. Simula- tion and analysis results reveal that proposed transmission indices possess significant advantages, such as normalized finite （ranging from 0 to l）, dimensionally homogeneous, frame-free, intuitive and easy to calculate. Besides, pro- posed indices well indicate the good transmission region and relativity to the singularity with better resolution than the traditional local conditioning index, and provide a novel tool for kinematic analysis and optimal design of fully parallel manipulators.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.5147113 and 51505037)the Fundamental Research Funds for the Central Universities of Ministry of Education of China(Grant Nos.3102017zy029,310832163402,and 310832163403)
文摘The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material design. At present,the quantitative characterization methods mainly rely on the microstructure characterization of shape, size, distribution,and volume fraction, which related to the mechanical properties. These traditional methods have been applied for several decades and the subjectivity of human factors induces unavoidable errors. In this paper, we try to bypass the traditional operations and identify the relationship between the microstructures and the material properties by the texture of image itself directly. The statistical approach is based on gray level Co-occurrence matrix（GLCM）, allowing an objective and repeatable study on material microstructures. We first present how to identify GLCM with the optimal parameters, and then apply the method on three systems with different microstructures. The results show that GLCM can reveal the interface information and microstructures complexity with less human impact. Naturally, there is a good correlation between GLCM and the mechanical properties.
文摘A novel topological index W F is defined by the matrices X,W and L as W F=XWL.The topological index WF based on the distance-related matrix of molecular graphs is used to code the structural environment of each atom-type in a molecular graph.Good QSPR models have been obtained for standard formation enthalpy of methyl halides.The result indicates that the idea of using multiple matrices to define the distance-related matrix topological index is valid.
文摘Data is humongous today because of the extensive use of World WideWeb, Social Media and Intelligent Systems. This data can be very important anduseful if it is harnessed carefully and correctly. Useful information can beextracted from this massive data using the Data Mining process. The informationextracted can be used to make vital decisions in various industries. Clustering is avery popular Data Mining method which divides the data points into differentgroups such that all similar data points form a part of the same group. Clusteringmethods are of various types. Many parameters and indexes exist for the evaluationand comparison of these methods. In this paper, we have compared partitioningbased methods K-Means, Fuzzy C-Means (FCM), Partitioning AroundMedoids (PAM) and Clustering Large Application (CLARA) on secure perturbeddata. Comparison and identification has been done for the method which performsbetter for analyzing the data perturbed using Extended NMF on the basis of thevalues of various indexes like Dunn Index, Silhouette Index, Xie-Beni Indexand Davies-Bouldin Index.
