BACKGROUND: Ankle brachial index (ABI) is widely involved in researches and clinical application of peripheral vascular injury of patients with diabetes mellitus (DM); however, the application in cerebral infarction (...BACKGROUND: Ankle brachial index (ABI) is widely involved in researches and clinical application of peripheral vascular injury of patients with diabetes mellitus (DM); however, the application in cerebral infarction (CI) is rare. OBJECTIVE: To investigate the possible risk factor of cerebral infarction plus peripheral arterial disease (PAD), compare metabolic characteristics of patients who having CI plus PAD or only having CI, and understand the significance of ABI on screening and diagnosing CI plus PAD of lower limb. DESIGN: Contrast observation based on CI patients. SETTING: Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region. PARTICIPANTS: A total of 124 CI patients were selected from Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region from July 2005 to April 2006, including 72 males and 52 females aged from 45 to 88 years. All patients met the diagnostic criteria of cerebrovascular disease established by National Academic Conference of Cerebrovascular Diseases in 1995 and determined as cerebral infarction with MRI or CT examination. All patients provided informed consent. There were 46 cases (37.2%) with CI plus PAD and 78 cases (62.8%) only with CI. METHODS: Blood pressure of bilateral ankles and upper extremities was measured at plain clinostatism with DINAMAP blood pressure monitor (GE Company). The ratio between average systolic pressure of lateral ankle and average systolic pressure of both upper extremities was regarded as ABI. The normal ABI was equal to or more than 0.9. If ABI < 0.9 occurred at one side, patients were diagnosed as PAD. On the second morning after hospitalization, blood was collected to measure fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG2h), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Among them, blood glucose, lipid and other biochemical markers were measured with enzyme chemistry assay and HbA1c was measured with HbA1c meter based on high liquid phase. Measurement data and enumeration data were compared with t test and Chi-square test, and multiple factors were dealt with Logistic regression analysis and multivariate linear regression analysis. MAIN OUTCOME MEASURES: Results of correlation between ABI and metabolic markers with multivariate linear regression analysis; risk factors of CI plus PAD with Logistic regression analysis; comparisons of metabolic markers between PAD and non-PAD patients. RESULTS: All 124 patients with acute CI were involved in the final analysis. ① Comparisons of metabolic markers: Levels of serum LDL-C and uric acid (UA) were higher of PAD patients than those of non-PAD patients (t =2.051 9, 3.339 1, P < 0.05); however, there were no significant differences among other metabolic markers (P > 0.05). ② Results of multivariate linear regression analysis: PBG2h, LDL-C and UA were obvious correlation with ABI of posterior tibial artery of lower limb and dorsal pedis artery (partial regression coefficient = -0.231 to -1.010, P < 0.05). ③ Risk factors of CI plus PAD with Logistic regression analysis: Age, smoking history, sum of CI focus (≥3) and LDL-C were independent risk factor of CI plus PAD (OR =1.524-5.422, P < 0.05-0.01). CONCLUSION: ① Levels of serum LDL-C and UA of patients with CI plus PAD are high. ② ABI of lower limbs is correlation with PBG2h, LDL-C and UA. In addition, measuring ABI is beneficial for early diagnosing PAD of lower limbs of patients who have poorly controlled blood glucose, abnormal lipid and poor renal function. ③ Age, LDL-C and sum of CI focus (≥3) are independent risk factors of CI plus PAD. It is of significance for screening non-PAD patients to evaluate risk degrees and prognosis and select therapeutic methods based on ABI measurement.展开更多
High costs are connected with upgrading railway embankments throughout Denmark using the partial factors for geotechnical design calibrated for general application. One way to reduce the costs is reliability-based cal...High costs are connected with upgrading railway embankments throughout Denmark using the partial factors for geotechnical design calibrated for general application. One way to reduce the costs is reliability-based calibration of the partial factors to a reasonable safety level taking into account the specific design situations and uncertainties relevant to railway embankments. A reliability-based design has been investigated, resulting in an optimal partial factor for the considered subsoil. With a stochastic soil model to simulate the undrained shear strength of soft soil deposits, the partial factor is calibrated using asymptotic sampling for the reliability assessment. The calibration shows that the partial factor can be reduced significantly compared to the value specified in the Danish National Annex to DS/EN 1997-1 （2007）, Eurocode 7.展开更多
This paper presents an adaptive fuzzy control scheme based on modified genetic algorithm. In the control scheme, genetic algorithm is used to optimze the nonlinear quantization functions of the controller and some key...This paper presents an adaptive fuzzy control scheme based on modified genetic algorithm. In the control scheme, genetic algorithm is used to optimze the nonlinear quantization functions of the controller and some key parameters of the adaptive control algorithm. Simulation results show that this control scheme has satisfactory performance in MIMO systems, chaotic systems and delay systems.展开更多
Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and ...Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and the disaster resistant and sustainable production condition.Correlation coefficient method and expert consultation method are used to determine the weight of evaluation index.After the standardization of extreme value,weighted sum method and multiple regression method are adopted to evaluate the influencing factors of agricultural land productivity in Huang-Huai Plain,China.Evaluation result shows that agricultural science and technology condition has a lower contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Resources condition has a higher contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Both the social and economic condition and the disaster control and sustainable production condition show relatively small contribution rate to the productivity of Huang-Huai Plain.It can be concluded that the main factors affecting the productivity of Huang-Huai Plain are the backward agricultural science and technology level,the poor farmland quality and the farmland infrastructure.Based on this,relevant suggestions are put forward to improve the farmland productivity of Huang-Huai Plain.展开更多
With correlation analysis and factor analysis methods, the effects of preceding Pacific SSTs on subtropical high indexes of main raining seasons are discussed. The results of correlation analysis show that the effects...With correlation analysis and factor analysis methods, the effects of preceding Pacific SSTs on subtropical high indexes of main raining seasons are discussed. The results of correlation analysis show that the effects of SSTs on five subtropical high indexes differ in seasons and regions. The variation of SSTs mostly affects the area and intensity indexes of the subtropical high, followed by the western ridge index, and the effect on the ridge line index is more remarkable than on the north boundary index. The results of factor analysis reveals that the first common factor of SST of each season reflected mainly the inverse relation of SSTs variation between the central and eastern part of equatorial Pacific and the western Pacific, which correlates better with the subtropical high indexes in the main raining seasons than other common factors of SST. The analysis of interdecadal variation indicated that the variation of SSTs was conducive to the emergence of the La Ni?a event before the end of 1970s, such that in the summer the subtropical high is likely to be weaker and smaller and located eastward and northward. After the 1980s, the opposite characteristics prevailed.展开更多
文摘BACKGROUND: Ankle brachial index (ABI) is widely involved in researches and clinical application of peripheral vascular injury of patients with diabetes mellitus (DM); however, the application in cerebral infarction (CI) is rare. OBJECTIVE: To investigate the possible risk factor of cerebral infarction plus peripheral arterial disease (PAD), compare metabolic characteristics of patients who having CI plus PAD or only having CI, and understand the significance of ABI on screening and diagnosing CI plus PAD of lower limb. DESIGN: Contrast observation based on CI patients. SETTING: Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region. PARTICIPANTS: A total of 124 CI patients were selected from Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region from July 2005 to April 2006, including 72 males and 52 females aged from 45 to 88 years. All patients met the diagnostic criteria of cerebrovascular disease established by National Academic Conference of Cerebrovascular Diseases in 1995 and determined as cerebral infarction with MRI or CT examination. All patients provided informed consent. There were 46 cases (37.2%) with CI plus PAD and 78 cases (62.8%) only with CI. METHODS: Blood pressure of bilateral ankles and upper extremities was measured at plain clinostatism with DINAMAP blood pressure monitor (GE Company). The ratio between average systolic pressure of lateral ankle and average systolic pressure of both upper extremities was regarded as ABI. The normal ABI was equal to or more than 0.9. If ABI < 0.9 occurred at one side, patients were diagnosed as PAD. On the second morning after hospitalization, blood was collected to measure fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG2h), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Among them, blood glucose, lipid and other biochemical markers were measured with enzyme chemistry assay and HbA1c was measured with HbA1c meter based on high liquid phase. Measurement data and enumeration data were compared with t test and Chi-square test, and multiple factors were dealt with Logistic regression analysis and multivariate linear regression analysis. MAIN OUTCOME MEASURES: Results of correlation between ABI and metabolic markers with multivariate linear regression analysis; risk factors of CI plus PAD with Logistic regression analysis; comparisons of metabolic markers between PAD and non-PAD patients. RESULTS: All 124 patients with acute CI were involved in the final analysis. ① Comparisons of metabolic markers: Levels of serum LDL-C and uric acid (UA) were higher of PAD patients than those of non-PAD patients (t =2.051 9, 3.339 1, P < 0.05); however, there were no significant differences among other metabolic markers (P > 0.05). ② Results of multivariate linear regression analysis: PBG2h, LDL-C and UA were obvious correlation with ABI of posterior tibial artery of lower limb and dorsal pedis artery (partial regression coefficient = -0.231 to -1.010, P < 0.05). ③ Risk factors of CI plus PAD with Logistic regression analysis: Age, smoking history, sum of CI focus (≥3) and LDL-C were independent risk factor of CI plus PAD (OR =1.524-5.422, P < 0.05-0.01). CONCLUSION: ① Levels of serum LDL-C and UA of patients with CI plus PAD are high. ② ABI of lower limbs is correlation with PBG2h, LDL-C and UA. In addition, measuring ABI is beneficial for early diagnosing PAD of lower limbs of patients who have poorly controlled blood glucose, abnormal lipid and poor renal function. ③ Age, LDL-C and sum of CI focus (≥3) are independent risk factors of CI plus PAD. It is of significance for screening non-PAD patients to evaluate risk degrees and prognosis and select therapeutic methods based on ABI measurement.
基金The funding initiating this work was provided by Banedanmark
文摘High costs are connected with upgrading railway embankments throughout Denmark using the partial factors for geotechnical design calibrated for general application. One way to reduce the costs is reliability-based calibration of the partial factors to a reasonable safety level taking into account the specific design situations and uncertainties relevant to railway embankments. A reliability-based design has been investigated, resulting in an optimal partial factor for the considered subsoil. With a stochastic soil model to simulate the undrained shear strength of soft soil deposits, the partial factor is calibrated using asymptotic sampling for the reliability assessment. The calibration shows that the partial factor can be reduced significantly compared to the value specified in the Danish National Annex to DS/EN 1997-1 （2007）, Eurocode 7.
文摘This paper presents an adaptive fuzzy control scheme based on modified genetic algorithm. In the control scheme, genetic algorithm is used to optimze the nonlinear quantization functions of the controller and some key parameters of the adaptive control algorithm. Simulation results show that this control scheme has satisfactory performance in MIMO systems, chaotic systems and delay systems.
文摘Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and the disaster resistant and sustainable production condition.Correlation coefficient method and expert consultation method are used to determine the weight of evaluation index.After the standardization of extreme value,weighted sum method and multiple regression method are adopted to evaluate the influencing factors of agricultural land productivity in Huang-Huai Plain,China.Evaluation result shows that agricultural science and technology condition has a lower contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Resources condition has a higher contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Both the social and economic condition and the disaster control and sustainable production condition show relatively small contribution rate to the productivity of Huang-Huai Plain.It can be concluded that the main factors affecting the productivity of Huang-Huai Plain are the backward agricultural science and technology level,the poor farmland quality and the farmland infrastructure.Based on this,relevant suggestions are put forward to improve the farmland productivity of Huang-Huai Plain.
文摘With correlation analysis and factor analysis methods, the effects of preceding Pacific SSTs on subtropical high indexes of main raining seasons are discussed. The results of correlation analysis show that the effects of SSTs on five subtropical high indexes differ in seasons and regions. The variation of SSTs mostly affects the area and intensity indexes of the subtropical high, followed by the western ridge index, and the effect on the ridge line index is more remarkable than on the north boundary index. The results of factor analysis reveals that the first common factor of SST of each season reflected mainly the inverse relation of SSTs variation between the central and eastern part of equatorial Pacific and the western Pacific, which correlates better with the subtropical high indexes in the main raining seasons than other common factors of SST. The analysis of interdecadal variation indicated that the variation of SSTs was conducive to the emergence of the La Ni?a event before the end of 1970s, such that in the summer the subtropical high is likely to be weaker and smaller and located eastward and northward. After the 1980s, the opposite characteristics prevailed.
