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基于Depth-wise卷积和视觉Transformer的图像分类模型 被引量:2
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作者 张峰 黄仕鑫 +1 位作者 花强 董春茹 《计算机科学》 CSCD 北大核心 2024年第2期196-204,共9页
图像分类作为一种常见的视觉识别任务,有着广阔的应用场景。在处理图像分类问题时,传统的方法通常使用卷积神经网络,然而,卷积网络的感受野有限,难以建模图像的全局关系表示,导致分类精度低,难以处理复杂多样的图像数据。为了对全局关... 图像分类作为一种常见的视觉识别任务,有着广阔的应用场景。在处理图像分类问题时,传统的方法通常使用卷积神经网络,然而,卷积网络的感受野有限,难以建模图像的全局关系表示,导致分类精度低,难以处理复杂多样的图像数据。为了对全局关系进行建模,一些研究者将Transformer应用于图像分类任务,但为了满足Transformer的序列化和并行化要求,需要将图像分割成大小相等、互不重叠的图像块,破坏了相邻图像数据块之间的局部信息。此外,由于Transformer具有较少的先验知识,模型往往需要在大规模数据集上进行预训练,因此计算复杂度较高。为了同时建模图像相邻块之间的局部信息并充分利用图像的全局信息,提出了一种基于Depth-wise卷积的视觉Transformer(Efficient Pyramid Vision Transformer,EPVT)模型。EPVT模型可以实现以较低的计算成本提取相邻图像块之间的局部和全局信息。EPVT模型主要包含3个关键组件:局部感知模块(Local Perceptron Module,LPM)、空间信息融合模块(Spatial Information Fusion,SIF)和“+卷积前馈神经网络(Convolution Feed-forward Network,CFFN)。LPM模块用于捕获图像的局部相关性;SIF模块用于融合相邻图像块之间的局部信息,并利用不同图像块之间的远距离依赖关系,提升模型的特征表达能力,使模型学习到输出特征在不同维度下的语义信息;CFFN模块用于编码位置信息和重塑张量。在图像分类数据集ImageNet-1K上,所提模型优于现有的同等规模的视觉Transformer分类模型,取得了82.6%的分类准确度,证明了该模型在大规模数据集上具有竞争力。 展开更多
关键词 深度学习 图像分类 depth-wise卷积 视觉Transformer 注意力机制
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基于改进FeatDepth的足球运动场景无监督单目图像深度预测
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作者 傅荟璇 徐权文 王宇超 《实验技术与管理》 CAS 北大核心 2024年第10期74-84,共11页
为了在降低成本的同时提高图像深度信息预测的精确度,并将深度估计应用于足球运动场景,提出一种基于改进FeatDepth的足球运动场景无监督单目图像深度预测方法。首先,对原FeatDepth引入注意力机制,使模型更加关注有效的特征信息;其次,将F... 为了在降低成本的同时提高图像深度信息预测的精确度,并将深度估计应用于足球运动场景,提出一种基于改进FeatDepth的足球运动场景无监督单目图像深度预测方法。首先,对原FeatDepth引入注意力机制,使模型更加关注有效的特征信息;其次,将FeatDepth中的PoseNet网络和DepthNet网络分别嵌入GAM全局注意力机制模块,为网络添加额外的上下文信息,在基本不增加计算成本的情况下提升FeatDepth模型深度预测性能;再次,为在低纹理区域和细节上获得更好的深度预测效果,由单视图重构损失与交叉视图重构损失组合而成最终的损失函数。选取KITTI数据集中Person场景较多的部分进行数据集制作并进行仿真实验,结果表明,改进后的FeatDepth模型不仅在精确度上有所提升,且在低纹理区域及细节处拥有更好的深度预测效果。最后,对比模型在足球场景下的推理效果后得出,改进后的模型在低纹理区域(足球、球门等)及细节处(肢体等)有更好的深度预测效果,实现了将基于无监督的单目深度估计模型应用于足球运动场景的目的。 展开更多
关键词 足球运动场景 无监督单目深度估计 Featdepth 注意力机制 GAM 图像重构
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Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma 被引量:1
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作者 Yi-Ying Wang Mei-Mei Shen Jian Gao 《World Journal of Gastroenterology》 SCIE CAS 2024年第8期901-918,共18页
BACKGROUND Metadherin(MTDH)is a key oncogene in most cancer types,including hepato-cellular carcinoma(HCC).Notably,MTDH does not affect the stemness pheno-type or immune infiltration of HCC.AIM To explore the role of ... BACKGROUND Metadherin(MTDH)is a key oncogene in most cancer types,including hepato-cellular carcinoma(HCC).Notably,MTDH does not affect the stemness pheno-type or immune infiltration of HCC.AIM To explore the role of MTDH on stemness and immune infiltration in HCC.METHODS MTDH expression in HCC tissues was detected using TCGA and GEO databases.Immunohistochemistry was used to analyze the tissue samples.MTDH was stably knocked down or overexpressed by lentiviral transfection in the two HCC cell lines.The invasion and migration abilities of HCC cells were evaluated using Matrigel invasion and wound healing assays.Next,we obtained liver cancer stem cells from the spheroids by culturing them in a serum-free medium.Gene expression was determined by western blotting and quantitative reverse transcri-ption PCR.Flow cytometry,immunofluorescence,and tumor sphere formation assays were used to characterize stem-like cells.The effects of MTDH inhibition on tumor growth were evaluated in vivo.The correlation of MTDH with immune cells,immunomodulators,and chemokines was analyzed using ssGSEA and TISIDB databases.RESULTS HCC tissues expressed higher levels of MTDH than normal liver tissues.High MTDH expression was associated with a poor prognosis.HCC cells overex-pressing MTDH exhibited stronger invasion and migration abilities,exhibited a stem cell-like phenotype,and formed spheres;however,MTDH inhibition attenuated these effects.MTDH inhibition suppressed HCC progression and CD133 expression in vivo.MTDH was positively correlated with immature dendritic,T helper 2 cells,central memory CD8^(+)T,memory B,activated dendritic,natural killer(NK)T,NK,activated CD4^(+)T,and central memory CD4^(+)T cells.MTDH was negatively correlated with activated CD8^(+)T cells,eosinophils,activated B cells,monocytes,macrophages,and mast cells.A positive correlation was observed between the MTDH level and CXCL2 expression,whereas a negative correlation was observed between the MTDH level and CX3CL1 and CXCL12 expression.CONCLUSION High levels of MTDH expression in patients with HCC are associated with poor prognosis,promoting tumor stemness,immune infiltration,and HCC progression. 展开更多
关键词 Metadherin Hepatocellular carcinoma Cancer stem cells Immune infiltration
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Edge enhanced depth perception with binocular meta-lens 被引量:2
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作者 Xiaoyuan Liu Jingcheng Zhang +5 位作者 Borui Leng Yin Zhou Jialuo Cheng Takeshi Yamaguchi Takuo Tanaka Mu Ku Chen 《Opto-Electronic Science》 2024年第9期4-13,共10页
The increasing popularity of the metaverse has led to a growing interest and market size in spatial computing from both academia and industry.Developing portable and accurate imaging and depth sensing systems is cruci... The increasing popularity of the metaverse has led to a growing interest and market size in spatial computing from both academia and industry.Developing portable and accurate imaging and depth sensing systems is crucial for advancing next-generation virtual reality devices.This work demonstrates an intelligent,lightweight,and compact edge-enhanced depth perception system that utilizes a binocular meta-lens for spatial computing.The miniaturized system comprises a binocular meta-lens,a 532 nm filter,and a CMOS sensor.For disparity computation,we propose a stereo-matching neural network with a novel H-Module.The H-Module incorporates an attention mechanism into the Siamese network.The symmetric architecture,with cross-pixel interaction and cross-view interaction,enables a more comprehensive analysis of contextual information in stereo images.Based on spatial intensity discontinuity,the edge enhancement eliminates illposed regions in the image where ambiguous depth predictions may occur due to a lack of texture.With the assistance of deep learning,our edge-enhanced system provides prompt responses in less than 0.15 seconds.This edge-enhanced depth perception meta-lens imaging system will significantly contribute to accurate 3D scene modeling,machine vision,autonomous driving,and robotics development. 展开更多
关键词 metasurfaces meta-lenses deep learning depth perception edge detection
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Surrogate modeling for unsaturated infiltration via the physics and equality-constrained artificial neural networks 被引量:1
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作者 Peng Lan Jingjing Su Sheng Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2282-2295,共14页
Machine learning(ML)provides a new surrogate method for investigating groundwater flow dynamics in unsaturated soils.Traditional pure data-driven methods(e.g.deep neural network,DNN)can provide rapid predictions,but t... Machine learning(ML)provides a new surrogate method for investigating groundwater flow dynamics in unsaturated soils.Traditional pure data-driven methods(e.g.deep neural network,DNN)can provide rapid predictions,but they do require sufficient on-site data for accurate training,and lack interpretability to the physical processes within the data.In this paper,we provide a physics and equalityconstrained artificial neural network(PECANN),to derive unsaturated infiltration solutions with a small amount of initial and boundary data.PECANN takes the physics-informed neural network(PINN)as a foundation,encodes the unsaturated infiltration physical laws(i.e.Richards equation,RE)into the loss function,and uses the augmented Lagrangian method to constrain the learning process of the solutions of RE by adding stronger penalty for the initial and boundary conditions.Four unsaturated infiltration cases are designed to test the training performance of PECANN,i.e.one-dimensional(1D)steady-state unsaturated infiltration,1D transient-state infiltration,two-dimensional(2D)transient-state infiltration,and 1D coupled unsaturated infiltration and deformation.The predicted results of PECANN are compared with the finite difference solutions or analytical solutions.The results indicate that PECANN can accurately capture the variations of pressure head during the unsaturated infiltration,and present higher precision and robustness than DNN and PINN.It is also revealed that PECANN can achieve the same accuracy as the finite difference method with fewer initial and boundary training data.Additionally,we investigate the effect of the hyperparameters of PECANN on solving RE problem.PECANN provides an effective tool for simulating unsaturated infiltration. 展开更多
关键词 Richards equation(RE) Unsaturated infiltration Data-driven solutions Numerical modeling Machine learning(ML)
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Effect of slope angle on fractured rock masses under combined influence of variable rainfall infiltration and excavation unloading 被引量:1
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作者 Xiaoshuang Li Qihang Li +3 位作者 Yunmin Wang Wei Liu Di Hou Chun Zhu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第10期4154-4176,共23页
Intense precipitation infiltration and intricate excavation processes are crucial factors that impact the stability and security of towering and steep rock slopes within mining sites.The primary aim of this research w... Intense precipitation infiltration and intricate excavation processes are crucial factors that impact the stability and security of towering and steep rock slopes within mining sites.The primary aim of this research was to investigate the progression of cumulative failure within a cracked rock formation,considering the combined effects of precipitation and excavation activities.The study was conducted in the Huangniuqian eastern mining area of the Dexing Copper Mine in Jiangxi Province,China.An engineering geological investigation was conducted,a physical model experiment was performed,numerical calculations and theoretical analysis were conducted using the matrix discrete element method(Mat-DEM),and the deformation characteristics and the effect of the slope angle of a fractured rock mass under different scenarios were examined.The failure and instability mechanisms of the fractured rock mass under three slope angle models were analyzed.The experimental results indicate that as the slope angle increases,the combined effect of rainfall infiltration and excavation unloading is reduced.A novel approach to simulating unsaturated seepage in a rock mass,based on the van Genuchten model(VGM),has been developed.Compared to the vertical displacement observed in a similar physical experiment,the average relative errors associated with the slope angles of 45,50,and 55were 2.094%,1.916%,and 2.328%,respectively.Accordingly,the combined effect of rainfall and excavation was determined using the proposed method.Moreover,the accuracy of the numerical simulation was validated.The findings contribute to the seepage field in a meaningful way,offering insight that can inform and enhance existing methods and theories for research on the underlying mechanism of ultra-high and steep rock slope instability,which can inform the development of more effective risk management strategies. 展开更多
关键词 Open-pit to underground excavation Rainfall infiltration Similarity simulation Numerical simulation Image recognition Slope angle
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Three-dimensional crystal defect imaging by STEM depth sectioning
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作者 Ryo Ishikawa Naoya Shibata Yuichi Ikuhara 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第8期2-7,共6页
One of the major innovations awaiting in electron microscopy is full three-dimensional imaging at atomic resolution.Despite the success of aberration correction to deep sub-angstrom lateral resolution,spatial resoluti... One of the major innovations awaiting in electron microscopy is full three-dimensional imaging at atomic resolution.Despite the success of aberration correction to deep sub-angstrom lateral resolution,spatial resolution in depth is still far from atomic resolution.In scanning transmission electron microscopy(STEM),this poor depth resolution is due to the limitation of the illumination angle.To overcome this physical limitation,it is essential to implement a next-generation aberration corrector in STEM that can significantly improve the depth resolution.This review discusses the capability of depth sectioning for three-dimensional imaging combined with large-angle illumination STEM.Furthermore,the statistical analysis approach remarkably improves the depth resolution,making it possible to achieve three-dimensional atomic resolution imaging at oxide surfaces.We will also discuss the future prospects of three-dimensional imaging at atomic resolution by STEM depth sectioning. 展开更多
关键词 atomic-resolution STEM STEM depth sectioning depth resolution DOPANTS surface topography
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Investigation of Groundwater Quality with Borehole Depth in the Basin Granitoids of the Ashanti Region of Ghana
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作者 Bernard Ofosu Augustine Kofi Asante +2 位作者 Festus Anane Mensah Umar-Farouk Usman Naa Korkoi Ayeh 《Journal of Water Resource and Protection》 CAS 2024年第5期381-394,共14页
The dependence of groundwater quality on borehole depth is usually debatable in groundwater studies, especially in complex geological formations where aquifer characteristics vary spatially with depth. This study ther... The dependence of groundwater quality on borehole depth is usually debatable in groundwater studies, especially in complex geological formations where aquifer characteristics vary spatially with depth. This study therefore seeks to investigate the relationship between borehole depth and groundwater quality across the granitoid aquifers within the Birimian Supergroup in the Ashanti Region. Physicochemical analysis records of groundwater quality data were collected from 23 boreholes of public and private institutions in the Ashanti Region of Ghana, and the parametric values of iron, fluoride, total hardness, pH, nitrate, and nitrite were used to study the groundwater quality-depth relationship. The results showed that the depth-to-groundwater quality indicated a marginal increase in water quality in the range of 30 to 50 m, which is mathematically represented by the low-value correlation coefficient (r<sup>2</sup> = 0.026). A relatively significant increase occurs in the depth range of 50 to 80 m, which is given by a correlation coefficient of r<sup>2</sup> = 0.298. The mean percent parameter compatibility was 74%, 82%, 89%, and 97% at 50, 60, 70, and 80 m depths, respectively. The variations in groundwater quality per depth ratio ranged from 1.48, 1.37, 1.27, and 1.21 for 50, 60, 70, and 80 m depth, respectively. The recommended minimum borehole depth for excellent groundwater quality is suggested with a compatibility per meter depth ratio of 1.37. This results in a range between 50 and 70 m as the most desirable drilling depth for excellent groundwater quality within the granitoids of the Birimian Supergroup of the Ashanti Region in Ghana. 展开更多
关键词 Groundwater Quality Borehole depth Birimian Supergroup Granitoid Aquifers Ashanti Region
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Perpendicular-Cutdepth:Perpendicular Direction Depth Cutting Data Augmentation Method
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作者 Le Zou Linsong Hu +2 位作者 Yifan Wang Zhize Wu Xiaofeng Wang 《Computers, Materials & Continua》 SCIE EI 2024年第4期927-941,共15页
Depth estimation is an important task in computer vision.Collecting data at scale for monocular depth estimation is challenging,as this task requires simultaneously capturing RGB images and depth information.Therefore... Depth estimation is an important task in computer vision.Collecting data at scale for monocular depth estimation is challenging,as this task requires simultaneously capturing RGB images and depth information.Therefore,data augmentation is crucial for this task.Existing data augmentationmethods often employ pixel-wise transformations,whichmay inadvertently disrupt edge features.In this paper,we propose a data augmentationmethod formonocular depth estimation,which we refer to as the Perpendicular-Cutdepth method.This method involves cutting realworld depth maps along perpendicular directions and pasting them onto input images,thereby diversifying the data without compromising edge features.To validate the effectiveness of the algorithm,we compared it with existing convolutional neural network(CNN)against the current mainstream data augmentation algorithms.Additionally,to verify the algorithm’s applicability to Transformer networks,we designed an encoder-decoder network structure based on Transformer to assess the generalization of our proposed algorithm.Experimental results demonstrate that,in the field of monocular depth estimation,our proposed method,Perpendicular-Cutdepth,outperforms traditional data augmentationmethods.On the indoor dataset NYU,our method increases accuracy from0.900 to 0.907 and reduces the error rate from0.357 to 0.351.On the outdoor dataset KITTI,our method improves accuracy from 0.9638 to 0.9642 and decreases the error rate from 0.060 to 0.0598. 展开更多
关键词 PERPENDICULAR depth estimation data augmentation
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SOX11 as a potential prognostic biomarker in hepatocellular carcinoma linked to immune infiltration and ferroptosis
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作者 Hongyu Chen Qiangguo Ao +3 位作者 Yueling Wang Yue Qian Qingli Cheng Wei Zhang 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2024年第4期378-397,共20页
Objective:SOX11 is expressed in numerous malignancies,including hepatocellular carcinomas(HCC),but its oncogenic function has not been elucidated.Here,we performed a comprehensive bioinformatics analysis of the Liver ... Objective:SOX11 is expressed in numerous malignancies,including hepatocellular carcinomas(HCC),but its oncogenic function has not been elucidated.Here,we performed a comprehensive bioinformatics analysis of the Liver Hepatocellular Carcinoma(LIHC)dataset to investigate the function of SOX11 in tumorgenesis.Methods:SOX11 expression data from The Cancer Genome Atlas(TCGA)and Gene Expression Omnibus(GEO)were validated by immunohistochemistry(IHC).Co-expression,differential expression,and functional analyses utilized TCGA-LIHC,Timer 2.0,Metascape,GTEx,and LinkedOmics databases.Associations with immune infiltration,ferroptosis,and immune checkpoint genes were assessed.Genetic changes were explored via CBioPortal.Logistic regression,receiver operating characteristic curve(ROC),Kaplan-Meier analysis,and nomogram modeling evaluated associations with HCC clinicopathological features.SOX11’s impact on proliferation and migration was studied in HepG2 and HuH7 cell lines.Results:SOX11 was significantly elevated in HCC tumors compared to controls.SOX11-associated genes exhibited differential expression in pathways involving extracellular membrane ion channels.Significant associations were found between SOX11 levels,immune infiltration,ferroptosis,and immune checkpoint genes in HCC tissue.SOX11 levels correlated with HCC stage,histologic grade,and tumor status,and independently predicted overall and disease-specific survival.SOX11 expression effectively distinguished between tumor and normal liver tissue.Spearman correlations highlighted a significant relationship between SOX11 and ferroptosis-associated genes.Decreased SOX11 levels in HepG2 and HuH7 cells resulted in reduced proliferation and migration.Conclusions:SOX11 was found to represent a promising biomarker within HCC diagnosis and prognosis together with being a possible drug-target. 展开更多
关键词 SOX11 BIOMARKER HCC PROGNOSIS genetic alterations tumor-immune infiltration ferroptosis
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Extraction of Acoustic Normal Mode Depth Functions Using Range-Difference Method with Vertical Linear Array Data
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作者 GAO Siyu LI Weilu +2 位作者 ZHANG Yinquan LI Xiaolei WANG Ning 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第4期871-882,共12页
Data-derived normal mode extraction is an effective method for extracting normal mode depth functions in the absence of marine environmental data.However,when the corresponding singular vectors become nonunique when t... Data-derived normal mode extraction is an effective method for extracting normal mode depth functions in the absence of marine environmental data.However,when the corresponding singular vectors become nonunique when two or more singular values obtained from the cross-spectral density matrix diagonalization are nearly equal,this results in unsatisfactory extraction outcomes for the normal mode depth functions.To address this issue,we introduced in this paper a range-difference singular value decomposition method for the extraction of normal mode depth functions.We performed the mode extraction by conducting singular value decomposition on the individual frequency components of the signal's cross-spectral density matrix.This was achieved by using pressure and its range-difference matrices constructed from vertical line array data.The proposed method was validated using simulated data.In addition,modes were successfully extracted from ambient noise. 展开更多
关键词 range difference depth function extraction normal mode
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CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma
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作者 SHUANGSHUANG ZENG XI CHEN +4 位作者 QIAOLI YI ABHIMANYU THAKUR HUI YANG YUANLIANG YAN SHAO LIU 《Oncology Research》 SCIE 2024年第2期261-272,共12页
Finding biomarkers for immunotherapy is an urgent issue in cancer treatment.Cellular retinoic acid-binding protein 2(CRABP2)is a controversial factor in the occurrence and development of human tumors.However,there is ... Finding biomarkers for immunotherapy is an urgent issue in cancer treatment.Cellular retinoic acid-binding protein 2(CRABP2)is a controversial factor in the occurrence and development of human tumors.However,there is limited research on the relationship between CRABP2 and immunotherapy response.This study found that negative correlations of CRABP2 and immune checkpoint markers(PD-1,PD-L1,and CTLA-4)were observed in breast invasive carcinoma(BRCA),skin cutaneous melanoma(SKCM),stomach adenocarcinoma(STAD)and testicular germ cell tumors(TGCT).In particular,in SKCM patients who were treated with PD-1 inhibitors,high levels of CRABP2 predicted poor prognosis.Additionally,CRABP2 expression was elevated in cancer-associated fibroblasts(CAFs)at the single-cell level.The expression of CRABP2 was positively correlated with markers of CAFs,such as MFAP5,PDPN,ITGA11,PDGFRα/βand THY1 in SKCM.To validate the tumor-promoting effect of CRABP2 in vivo,SKCM xenograft mice models with CRABP2 overexpression have been constructed.These models showed an increase in tumor weight and volume.Enrichment analysis indicated that CRABP2 may be involved in immunerelated pathways of SKCM,such as extracellular matrix(ECM)receptor interaction and epithelial-mesenchymal transition(EMT).The study suggests that CRABP2 may regulate immunotherapy in SKCM patients by influencing infiltration of CAFs.In conclusion,this study provides new insights into the role of CRABP2 in immunotherapy response.The findings suggest that CRABP2 may be a promising biomarker for PD-1 inhibitors in SKCM patients.Further research is needed to confirm these findings and to explore the clinical implications of CRABP2 in immunotherapy. 展开更多
关键词 CRABP2 MELANOMA PD-1 Cancer-associated fibroblasts Immune infiltration
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A Prognostic Biomarker for Bladder Cancer Correlated with Immune Infiltration Is PAEP
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作者 Ning Tang Shasha Gai Qun Huang 《Journal of Biosciences and Medicines》 2024年第4期185-209,共25页
Background: A major cause of cancer death worldwide is bladder cancer, which is the most common malignant tumor of the urinary tract. PAEP is a member of the kernel lipocalin superfamily whose members share relatively... Background: A major cause of cancer death worldwide is bladder cancer, which is the most common malignant tumor of the urinary tract. PAEP is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The purpose of this study was to clarify the correlation between PAEP expression level and bladder cancer. Methods: In the TCGA database, we obtained clinical and RNA sequencing data of 431 BLCA patients, including 412 BLCA tissues and 19 normal bladder tissues in the study. Analyses of bioinformatics were conducted in this study to determine the role of PAEP in bladder cancer. A quantitative real-time PCR method was used to quantitate the gene expression profile. Additionally, the effect of PAEP on tumor immune infiltration and prognosis was analyzed. Results: PAEP was a poor prognostic biomarker of bladder cancer because it was significantly upregulated. bladder cancer patients with higher PAEP expression had poor outcomes. An AUC of 0.780 was calculated from the area under the ROC curve. PAEP was associated with T stage, pathologic stage, Histologic grade and Subtype of bladder cancer patients, and served as an independent predictor of overall survival in bladder cancer patients. Functional enrichment analysis revealed PAEP was obviously enriched in pathways connected with carcinogenesis and immunosuppression. The expression of PAEP was significantly associated with tumor immune cells and immune checkpoints according to ssGSEA and Spearman correlation analysis. Conclusions: In this study, we screened and detected a mRNA, PAEP is a prognostic and immune-related biomarker in BLCA, which may contribute to the early diagnosis and treatment of BLCA. 展开更多
关键词 PAEP Bladder Cancer Immune Cell infiltration Immune Checkpoint PROGNOSIS
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The penetration depth of atomic radicals in tubes with catalytic surface properties
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作者 Domen PAUL Miran MOZETIC +3 位作者 Rok ZAPLOTNIK Alenka VESEL Gregor PRIMC Denis DONLAGIC 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第7期157-164,共8页
Catalysis of molecular radicals is often performed in interesting experimental configurations.One possible configuration is tubular geometry.The radicals are introduced into the tubes on one side,and stable molecules ... Catalysis of molecular radicals is often performed in interesting experimental configurations.One possible configuration is tubular geometry.The radicals are introduced into the tubes on one side,and stable molecules are exhausted on the other side.The penetration depth of radicals depends on numerous parameters,so it is not always feasible to calculate it.This article presents systematic measurements of the penetration depth of oxygen atoms along tubes made from nickel,cobalt,and copper.The source of O atoms was a surfatron-type microwave plasma.The initial density of O atoms depended on the gas flow and was 0.7×10^(21)m^(-3),2.4×10^(21)m^(-3),and 4.2×10^(21)m^(-3)at the flow rates of 50,300,and 600 sccm,and pressures of 10,35,and 60 Pa,respectively.The gas temperature remained at room temperature throughout the experiments.The dissociation fraction decreased exponentially along the length of the tubes in all cases.The penetration depths for well-oxidized nickel were 1.2,1.7,and 2.4 cm,respectively.For cobalt,they were slightly lower at 1.0,1.3,and 1.6 cm,respectively,while for copper,they were 1.1,1.3,and 1.7 cm,respectively.The results were explained by gas dynamics and heterogeneous surface association.These data are useful in any attempt to estimate the loss of molecular fragments along tubes,which serve as catalysts for the association of various radicals to stable molecules. 展开更多
关键词 oxygen plasma penetration depth CATALYSIS heterogeneous surface recombination atom loss
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Effects of diamond particle size on microstructure and properties of diamond/Al-12Si composites prepared by vacuum-assisted pressure infiltration
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作者 Jia-ping Fu Can-xu Zhou +1 位作者 Guo-fa Mi Yuan Liu 《China Foundry》 SCIE EI CAS CSCD 2024年第4期360-368,共9页
Diamond/aluminium composites have attracted attention in the field of thermal management of electronic packaging for their excellent properties.In order to solve the interfacial problem between diamond and aluminium,a... Diamond/aluminium composites have attracted attention in the field of thermal management of electronic packaging for their excellent properties.In order to solve the interfacial problem between diamond and aluminium,a novel process combining pressure infiltration with vacuum-assisted technology was proposed to prepare diamond/aluminum composites.The effect of diamond particle size on the microstructure and properties of the diamond/Al-12Si composites was investigated.The results show that the diamond/Al-12Si composites exhibit high relative density and a uniform microstructure.Both thermal conductivity and coefficient of thermal expansion increase with increasing particle size,while the bending strength exhibits the opposite trend.When the average diamond particle size increases from 45μm to 425μm,the thermal conductivity of the composites increases from 455 W·m^(-1)·K^(-1)to 713 W·m^(-1)·K^(-1)and the coefficient of thermal expansion increases from 4.97×10^(-6)K^(-1)to 6.72×10^(-6)K^(-1),while the bending strength decreases from 353 MPa to 246 MPa.This research demonstrates that high-quality composites can be prepared by the vacuum-assisted pressure infiltration process and the thermal conductivity of the composites can be effectively improved by increasing the diamond particle size. 展开更多
关键词 diamond/aluminum composites thermal conductivity electronic packaging vacuum-assisted pressure infiltration
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Microstructure and Oxidation Behavior of ZrB_(2)-SiC Ceramics Fabricated by Tape Casting and Reactive Melt Infiltration
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作者 TAN Min CHEN Xiaowu +5 位作者 YANG Jinshan ZHANG Xiangyu KAN Yanmei ZHOU Haijun XUE Yudong DONG Shaoming 《无机材料学报》 SCIE EI CAS CSCD 北大核心 2024年第8期955-964,共10页
ZrB_(2)-based ceramics typically necessitate high temperature and pressure for sintering,whereas ZrB_(2)-SiC ceramics can be fabricated at 1500℃using the process of reactive melt infiltration with Si.In comparison to... ZrB_(2)-based ceramics typically necessitate high temperature and pressure for sintering,whereas ZrB_(2)-SiC ceramics can be fabricated at 1500℃using the process of reactive melt infiltration with Si.In comparison to the conventional preparation method,reactive synthesis allows for the more facile production of ultra-high temperature ceramics with fine particle size and homogeneous composition.In this work,ZrSi_(2),B4C,and C were used as raw materials to prepare ZrB_(2)-SiC via combination of tape casting and reactive melt infiltration herein referred to as ZBC ceramics.Control sample of ZrB_(2)-SiC was also prepared using ZrB_(2) and SiC as raw materials through an identical process designated as ZS ceramics.Microscopic analysis of both ceramic groups revealed smaller and more uniformly distributed particles of the ZrB_(2) phase in ZBC ceramics compared to the larger particles in ZS ceramics.Both sets of ceramics underwent cyclic oxidation testing in the air at 1600℃for a cumulative duration of 5 cycles,each cycle lasting 2 h.Analysis of the oxidation behavior showed that both ZBC ceramics and ZS ceramics developed a glassy SiO_(2)-ZrO_(2) oxide layer on their surfaces during the oxidation.This layer severed as a barrier against oxygen.In ZBC ceramics,ZrO_(2) is finely distributed in SiO_(2),whereas in ZS ceramics,larger ZrO_(2) particles coexist with glassy SiO_(2).The surface oxide layer of ZBC ceramics maintains a dense structure because the well-dispersed ZrO_(2) increases the viscosity of glassy SiO_(2),preventing its crystallization during the cooling.Conversely,some SiO_(2) in the oxide layer of ZS ceramics may crystallize and form a eutectic with ZrO_(2),leading to the formation of ZrSiO_(4).This leads to cracking of the oxide layer due to differences in thermal expansion coefficients,weakening its barrier effect.An analysis of the oxidation resistance shows that ZBC ceramics exhibit less increase in oxide layer thickness and mass compared to ZS ceramics,suggesting superior oxidation resistance of ZBC ceramics. 展开更多
关键词 ultra-high temperature ceramic ZRB2-SIC oxidation behavior reactive melt infiltration
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Infiltration,runoff,and slope stability behaviors of infinite slope with macropores based on an improved Green–Ampt model
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作者 LI Shanghui WU Guoxiong +2 位作者 QUE Yun JIANG Zhenliang CHENG Gaoyun 《Journal of Mountain Science》 SCIE CSCD 2024年第7期2220-2235,共16页
Infiltration–runoff–slope instability mechanism of macropore slope under heavy rainfall is unclear.This paper studied its instability mechanism with an improved Green–Ampt(GA)model considering the dual-porosity(i.e... Infiltration–runoff–slope instability mechanism of macropore slope under heavy rainfall is unclear.This paper studied its instability mechanism with an improved Green–Ampt(GA)model considering the dual-porosity(i.e.,matrix and macropore)and ponding condition,and proposed the infiltration equations,infiltration–runoff coupled model,and safety factor calculation method.Results show that the infiltration processes of macropore slope can be divided into three stages,and the proposed model is rational by a comparative analysis.The wetting front depth of the traditional unsaturated slope is 17.2%larger than that of the macropore slope in the early rainfall stage and 27%smaller than that of the macropore slope in the late rainfall stage.Then,macropores benefit the slope stability in the early rainfall but not in the latter.Macropore flow does not occur initially but becomes pronounced with increasing rainfall duration.The equal depth of the wetting front in the two domains is regarded as the onset criteria of macropore flow.Parameter analysis shows that macropore flow is delayed by increasing proportion of macropore domain(ω_(f)),whereas promoted by increasing ratio of saturated permeability coefficients between the two domains(μ).The increasing trend of ponding depth is sharp at first and then grows slowly.Finally,when rainfall duration is less than 3 h,ωf andμhave no significant effect on the safety factor,whereas it decreases with increasingωf and increases with increasingμunder longer duration(≥3 h).With the increase ofω_(f),the slope maximum instability time advances by 10.5 h,and with the increase ofμ,the slope maximum instability time delays by 3.1 h. 展开更多
关键词 Macropore slope Green–Ampt infiltration model Equivalent wetting front Ponding response time Slope stability
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HVSR analysis of pumice sands for sediment depth characterization:A case study for Guadalajara,Mexico
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作者 Hafid Salgado M. Alejandro Ramírez-Gaytan +1 位作者 Adolfo Preciado Christian R.Escudero 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第3期577-591,共15页
The horizontal to vertical spectral ratio(HVSR)methodology is used here to characterize pumice soils and to image the three-dimensional surface geometry of Guadalajara,Mexico.Similar to other Latin American cities,Gua... The horizontal to vertical spectral ratio(HVSR)methodology is used here to characterize pumice soils and to image the three-dimensional surface geometry of Guadalajara,Mexico.Similar to other Latin American cities,Guadalajara is exposed to high seismic risk,with the particularity of being the largest urban settlement in Latin America built on pumice soils.Methodology has not yet been tested to characterize subsoil depths in pumice sands.Due to the questionable use of traditional geotechnical tests for the analysis of pumice soils,HVSR provides an alternative for its characterization without altering its fragile and porous structure.In this work,resonance frequency(F0)and peak amplitude(A0)are used to constrain the depth of the major impedance contrast that represents the interface between bedrock and pumice soil.Results were compared with borehole depths and other available geotechnical and geophysical data and show good agreement.One of the profiles estimated on the riverbanks that cross the city,reveals different subsoil thickness that could have an impact on different site responses on riverine areas to an eventual earthquake.Government and academic efforts are combined in this work to characterize depth sediments,an important parameter that impacts the regulations for construction in the city. 展开更多
关键词 subsoil of Guadalajara shallow soil thickness bedrock depth pumice soil characterization
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Effect of burial depth of a new tunnel on the seismic response of an existing tunnel
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作者 Ma Runbo Cao Qikun +3 位作者 Lu Shasha Zhao Dongxu Zhang Yanan Xu Hong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第4期863-882,共20页
Burial depth is a crucial factor affecting the forces and deformation of tunnels during earthquakes.One key issue is a lack of understanding of the effect of a change in the buried depth of a single-side tunnel on the... Burial depth is a crucial factor affecting the forces and deformation of tunnels during earthquakes.One key issue is a lack of understanding of the effect of a change in the buried depth of a single-side tunnel on the seismic response of a double-tunnel system.In this study,shaking table tests were designed and performed based on a tunnel under construction in Dalian,China.Numerical models were established using the equivalent linear method combined with ABAQUS finite element software to analyze the seismic response of the interacting system.The results showed that the amplification coefficient of the soil acceleration did not change evidently with the burial depth of the new tunnel but decreased as the seismic amplitude increased.In addition,the existing tunnel acceleration,earth pressure,and internal force were hardly affected by the change in the burial depth;for the new tunnel,the acceleration and internal force decreased as the burial depth increased,while the earth pressure increased.This shows that the earth pressure distribution in a double-tunnel system is relatively complex and mainly concentrated on the arch spandrel and arch springing of the relative area.Overall,when the horizontal clearance between the center of the two tunnels was more than twice the sum of the radius of the outer edges of the two tunnels,the change in the burial depth of the new tunnel had little effect on the existing one,and the tunnel structure was deemed safe.These results provide a preliminary understanding and reference for the seismic performance of a double-tunnel system. 展开更多
关键词 burial depth new tunnel existing tunnel seismic response shaking table tests numerical simulations
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Quantitative prediction model for the depth limit of oil accumulation in the deep carbonate rocks:A case study of Lower Ordovician in Tazhong area of Tarim Basin
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作者 Wen-Yang Wang Xiong-Qi Pang +3 位作者 Ya-Ping Wang Zhang-Xin Chen Fu-Jie Jiang Ying Chen 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期115-124,共10页
With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration field.Hence,the extent to which oil exploration can b... With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration field.Hence,the extent to which oil exploration can be extended,and the prediction of the depth limit of oil accumulation(DLOA),are issues that have attracted significant attention in petroleum geology.Since it is difficult to characterize the evolution of the physical properties of the marine carbonate reservoir with burial depth,and the deepest drilling still cannot reach the DLOA.Hence,the DLOA cannot be predicted by directly establishing the relationship between the ratio of drilling to the dry layer and the depth.In this study,by establishing the relationships between the porosity and the depth and dry layer ratio of the carbonate reservoir,the relationships between the depth and dry layer ratio were obtained collectively.The depth corresponding to a dry layer ratio of 100%is the DLOA.Based on this,a quantitative prediction model for the DLOA was finally built.The results indicate that the porosity of the carbonate reservoir,Lower Ordovician in Tazhong area of Tarim Basin,tends to decrease with burial depth,and manifests as an overall low porosity reservoir in deep layer.The critical porosity of the DLOA was 1.8%,which is the critical geological condition corresponding to a 100%dry layer ratio encountered in the reservoir.The depth of the DLOA was 9,000 m.This study provides a new method for DLOA prediction that is beneficial for a deeper understanding of oil accumulation,and is of great importance for scientific guidance on deep oil drilling. 展开更多
关键词 Deep layer Tarim Basin Hydrocarbon accumulation depth limit of oil accumulation Prediction model
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