Purpose:The notable increase in retraction papers has attracted considerable attention from diverse stakeholders.Various sources are now offering information related to research integrity,including concerns voiced on ...Purpose:The notable increase in retraction papers has attracted considerable attention from diverse stakeholders.Various sources are now offering information related to research integrity,including concerns voiced on social media,disclosed lists of paper mills,and retraction notices accessible through journal websites.However,despite the availability of such resources,there remains a lack of a unified platform to consolidate this information,thereby hindering efficient searching and cross-referencing.Thus,it is imperative to develop a comprehensive platform for retracted papers and related concerns.This article aims to introduce“Amend,”a platform designed to integrate information on research integrity from diverse sources.Design/methodology/approach:The Amend platform consolidates concerns and lists of problematic articles sourced from social media platforms(e.g.,PubPeer,For Better Science),retraction notices from journal websites,and citation databases(e.g.,Web of Science,CrossRef).Moreover,Amend includes investigation and punishment announcements released by administrative agencies(e.g.,NSFC,MOE,MOST,CAS).Each related paper is marked and can be traced back to its information source via a provided link.Furthermore,the Amend database incorporates various attributes of retracted articles,including citation topics,funding details,open access status,and more.The reasons for retraction are identified and classified as either academic misconduct or honest errors,with detailed subcategories provided for further clarity.Findings:Within the Amend platform,a total of 32,515 retracted papers indexed in SCI,SSCI,and ESCI between 1980 and 2023 were identified.Of these,26,620(81.87%)were associated with academic misconduct.The retraction rate stands at 6.64 per 10,000 articles.Notably,the retraction rate for non-gold open access articles significantly differs from that for gold open access articles,with this disparity progressively widening over the years.Furthermore,the reasons for retractions have shifted from traditional individual behaviors like falsification,fabrication,plagiarism,and duplication to more organized large-scale fraudulent practices,including Paper Mills,Fake Peer-review,and Artificial Intelligence Generated Content(AIGC).Research limitations:The Amend platform may not fully capture all retracted and concerning papers,thereby impacting its comprehensiveness.Additionally,inaccuracies in retraction notices may lead to errors in tagged reasons.Practical implications:Amend provides an integrated platform for stakeholders to enhance monitoring,analysis,and research on academic misconduct issues.Ultimately,the Amend database can contribute to upholding scientific integrity.Originality/value:This study introduces a globally integrated platform for retracted and concerning papers,along with a preliminary analysis of the evolutionary trends in retracted papers.展开更多
Gastric cancer(GC)is a malignant tumor originating from the gastric epithelium,and its incidence and mortality rates rank third among all malignant tumors worldwide.It is also one of the most common cancers in China a...Gastric cancer(GC)is a malignant tumor originating from the gastric epithelium,and its incidence and mortality rates rank third among all malignant tumors worldwide.It is also one of the most common cancers in China and is treated predominantly by Western medicine in clinical practice.However,with the advancements in medical technology and informatics,the values of traditional Chinese medicine(TCM)in preventing and treating GC and improving prognosis have increasingly been recognized.According to TCM,clinical manifestations of GC can be divided into Yege(dysphagia),regurgitation,stomach pain,and Zhengxia(abdominal mass).Due to the unbalanced distribution of health care resources in China,most GC patients already have progressive or advanced-stage disease at the first diagnosis.As a result,most GC patients have poor physical function,and surgery or chemotherapy alone will aggravate the impairment to the immune function and seriously affect the quality of life.In contrast,TCM therapies have shown promising efficacy in the management of these patients.Here we review the role of the integrated TCM and Western medicine in treating advanced GC.展开更多
The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also br...The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust,ensure patient safety,and uphold data integrity.This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.展开更多
With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Techn...With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research.展开更多
It is imperative that all stakeholders within the research ecosystem take responsibility to improve research integrity and reliability of published research.Based on the unique experiences of a specialist publishing e...It is imperative that all stakeholders within the research ecosystem take responsibility to improve research integrity and reliability of published research.Based on the unique experiences of a specialist publishing ethics and research integrity team within a major publisher,this article provides insights into the observed trends of misconduct and how those have evolved over time,and addresses key actions needed to improve the interface between researchers,funders,institutions and publishers to collectively improve research integrity on a global scale.展开更多
To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care an...To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care and summarized the available evidence.Pragmatic randomized controlled trials(pRCTs)and clinical registry studies are becoming more popular as they could compensate for the limitations of RCTs.Many RCTs of TCM for cancer treatment as well as systematic reviews have been published.The most investigated therapies are based on acupuncture,Chinese herbal compounds,and Chinese patent medicines.Acupuncture has a significant advantage in relieving cancer-related symptoms.Published studies focus more on improving clinical symptoms and laboratory indicators.However,the patient's quality of life deserves more attention.展开更多
Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environm...Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environmental degrada- tion and rural poverty in mountainous regions of northern Thailand and northern Vietnam are discussed in this paper. We present two examples from the Thai component of the research program to show how different disciplines and stakeholders need to cooperate at different scales to make meaningful scientific contributions towards sustainable land use and rural development in mountainous regions. The case of resource conservation in the Thai highlands shows that local and scientific knowledge, conven- tional surveys and participatory modeling can be creatively combined. Integrated research on the potential of integrating fruit trees and associated technologies into mountain farming systems suggests that natural scientists have to work alongsideeconomists and social scientists to avoid harmful effects of purely technology-driven and productivity- enhancing approaches. The success of new technologies cannot be measured solely by adoption rates and yield increases, but also needs to take into account their long-term impact on various groups of farmers and the ecological, economic and social trade-offs that they entail. Technical and institutional innovations need to go hand in hand to provide viable livelihood opportunities for smallholder farmers in mountain watersheds. The major lesson learned from the first six years of our research in the mountains of Thailand and Vietnam is that conventional and participatory approaches are not antagonistic; if scientists from various disciplines and research paradigms are open-minded, the combination of both approaches can produce meaningful results that cater for the needs of both the academic community and local stakeholders in mountain environments.展开更多
Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunolog...Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunology includes immunological regulation of fertility, materno-fetal immuno-regu-lation, and neuro-reproductive endocrino-immune network. With the integrated traditional Chinese and western medicine (ICWM) applied to reproductive immunology it has been greatly enriched in research contents and depth. The present review is to introduce the recent progresses in research of integrated medicine on reproductive immunology.展开更多
The sediment content of the Yellow River is resulted from the interactions of natural, economic, and social factors, so it includes some evolutive information of the Yellow River Basin system. Sediment contents from 1...The sediment content of the Yellow River is resulted from the interactions of natural, economic, and social factors, so it includes some evolutive information of the Yellow River Basin system. Sediment contents from 1952 to 2007 on Toudaoguai, Tongguan, Huayuankou and Lijin sections along the river are chosen as the study time series, and correlation dimensions (D2), Kolmogorov entropies (K2), and Hurst indexes (H) of the time series were calculated. Correlation dimensions on Toudaoguai, Tongguan, Huayuankou, and Lijin sections are 3.24, 5.69, 6.57 and 7.34 respectively, and the Kolmogorov entropies are 0.13, 0.37, 0.40 and 0.38 respectively, which indicates that the systems controlled by different sections along the Yellow River are chaotic systems and the chaotic degrees increase gradually from the upper to lower section. The average predictable period of the sediment contents is 8 years on Toudaoguai section and 3 years on the other sections with the reciprocals of the Kolmogorov entropies. The more obvious the chaotic degree is, the shorter the average predictable period is. Hurst indexes on the sections are above 0.5, with the maximum of 0.86 on Tongguan section and the minimum of 0.68 on Toudaoguai section, which indicates that the time series have persistent trends in the average predictable period. Eight state variables and two control parameters are necessary to construct the dynamic model of the Yellow River Basin system.展开更多
In order to further clarify the function and important value of the integration of production and education for the development of vocational education,this paper combed the development context of the integration of p...In order to further clarify the function and important value of the integration of production and education for the development of vocational education,this paper combed the development context of the integration of production and education in China's vocational education from three dimensions:policy evolution,research evolution and practice promotion.Studies have shown that the integration of production and education,as a distinctive type characteristic of vocational education in China,has experienced four stages of evolution in policy:the period of combination of production and education,the preparation and presentation period,the full implementation period and the in-depth promotion period,and the initially-constructed institutional system reflects developmental characteristics.In academic research,there are obvious policy-driven characteristics.The theoretical framework tends to be perfect,and the concept connotation and promotion path are gradually getting clear,but the research on regional promotion modes is slightly insufficient.The empirical research is weak,and the operability of countermeasure research is not strong.Moreover,the problem of discussing integration based on education is more prominent.In practice and promotion,the characteristic of the integration of production and education is gradually highlighted and deepened in terms of talent training,school-running system and school-running mode,and the carriers and contents of the integration of production and education are gradually enriched.展开更多
Device physics research for submicron and deep submicron space microelectronics devices and integrated circuits will be described in three topics.1.Thin film submicron and deep submicron SOS / CMOS devices and integra...Device physics research for submicron and deep submicron space microelectronics devices and integrated circuits will be described in three topics.1.Thin film submicron and deep submicron SOS / CMOS devices and integrated circuits.2.Deep submicron LDD CMOS devices and integrated circuits.3.C band and Ku band microwave GaAs MESFET and III-V compound hetrojunction HEM T and HBT devices and integrated circuits.展开更多
University libraries,as an integral component of university research capabilities,are tasked with serving education by providing research support to faculty and students.This study adopts an affordance research perspe...University libraries,as an integral component of university research capabilities,are tasked with serving education by providing research support to faculty and students.This study adopts an affordance research perspective originating from ecological psychology to explore the optimization path of research support services in libraries in the new media era.Based on the characteristics of university library services,this research analyzes three aspects:production affordance,mobile affordance,and social affordance,and proposes practical recommendations to guide future research service practices of university libraries.展开更多
The modern history of management systems is almost the same as the history ofmodem management science. Implicit management systems have been in existence for many 100s ofyears. ISO has paid attention to the issue of t...The modern history of management systems is almost the same as the history ofmodem management science. Implicit management systems have been in existence for many 100s ofyears. ISO has paid attention to the issue of the integrated management systems since the ISO 9000family standards for quality management systems (QMS) and ISO 14000 series standards for environmentmanagement system (EMS) were published. ISO/TAG (Technical Advisory Group) 12 was formed by theISO/TM (Technical Management Board) in early 1997 with the mandate to achieve greater compatibilitybetween the relevant ISO/TC 176 and ISO/TC 207 standards in the field of management systems,auditing, terms and definitions. The report was submitted to TMB by TAG 12 in 1999.展开更多
1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that re...1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that require high reliability,such as the aerospace industry,surface integrity is one of the most relevant indexes used to evaluate the quality of machined parts.Thus,obtaining updated knowledge on surface integrity is of great interest to both the academic community and industry[1].展开更多
Tobacco black shank is one of the devastating diseases of tobacco. In recent years, this disease widely occurred in most tobacco-growing areas, which caused disastrous losses and has severely threatened the sustainabl...Tobacco black shank is one of the devastating diseases of tobacco. In recent years, this disease widely occurred in most tobacco-growing areas, which caused disastrous losses and has severely threatened the sustainable development of flue-cured tobacco. In order to lay a theoretical foundation for the better control of tobacco black shank, the occurrence characteristics and integrated control strategis of this disease were systematically discussed according to the aspects of agricultural control, chemical control, biological control, etc.展开更多
Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foreste...Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foresters and animal scientists is generally designed to maximize the yield of products within their particular area of expertise (edible plant parts, tree products and livestock products, respectively), while soil scientists aim largely to increase soil nutrient stocks. At landscape level the same dynamic holds within the agronomic sciences, while water engineers work independently to conserve water through its isolation from broader landscape dynamics, and other common property resources remain largely ignored. Opportunities to foster positive synergies between system components, and to integrate livelihood with conservation goals, are generally missed. This paper presents experiences of the African Highlands Initiative, an ecoregional program of the Consultative Group for International Agricultural Research (CGIAR) and a network of the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA), in operationalizing integrated research at farm and landscape scale. Following a discussion of the shortcomings of the conventional research paradigm that beg for strongerintegration and a review of the contributions of extant research paradigms that help us move in the right direction, the paper lays a conceptual foundation for integrated research. System components at farm and landscape level are delineated, and this somewhat arbitrary conceptual partitioning of agroecological systems shown to influence the current research paradigm as well as the partitioning of institutional mandates. Diverse meanings of systems integration are then discussed to illustrate the synergies that might be built into agricultural and natural resource research programs. The distinction between the logic of maximization and optimization is then utilized to distinguish between component and “system-level” goals. This conceptual overview is followed by several case studies to illustrate how these concepts can guide the formulation of integrated research objectives, methods and outputs at farm and landscape scale. The paper concludes with a discussion of the implications of this alternative research paradigm for the structure, function and skill base of national and international agricultural research systems.展开更多
Primary liver cancer(PLC) is one of the most common malignant tumors in China. PLC is characterized by insidious onset, rapid progress, poor quality of life, and short survival time. Notably, current treatment strateg...Primary liver cancer(PLC) is one of the most common malignant tumors in China. PLC is characterized by insidious onset, rapid progress, poor quality of life, and short survival time. Notably, current treatment strategies remain unsatisfactory. Traditional Chinese medicines(TCM) have been used to treat a variety of diseases, including liver diseases, for more than 2000 years. In this study, we performed a review of the use frequency and clinical efficacy of TCM in treating PLC. Relevant literature from January 1, 2009, to January 1, 2021 was retrieved from network databases of China National Knowledge Infrastructure(CNKI), Chongqing VIP, Wanfang, PubMed, and SinoMed. The most frequently used TCM and their efficacy in PLC treatment were summarized. Based on the inclusion and exclusion criteria, 33 articles were selected. Overall, the efficacy of the combination of TCM and Western medicines in the treatment of PLC was higher than that in the control groups(i.e. treatment with Western medicines alone)(65.11% vs.44.31%, P <.05). Among the 33 selected articles, 11 were investigated for TCM preparation(marketed drugs) and 22 for TCM formulas. In total, 102 types of TCM(single herbs) were used to treat PLC. The top five most frequently used TCM were Poria(14.71%), Astragali radix(13.73%), Atractylodis Macrocephalae Rhizoma(12.75%), Bupleuri radix(12.75%), and Glycyrrhizae radix et Rhizoma(11.76%). Of the 102 types of TCM, tonics were the most frequently used categories, followed by heat-clearing medicines, blood-invigorating medicines, and stasis-resolving medicines. Of 207 papers, 174(84.06%) could not be subjected to statistical analysis due to research quality. Further high-quality research on herb sources, formula components and dosage, toxicology, and ethics of TCM is necessary. In conclusion, TCM play a promising role in the treatment and management of PLC, although further investigations are warranted.展开更多
This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends ...This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends in health sciences libraries to increase research skills of librarians in order to foster expanded research integration within the health sciences disciplines,the University of Michigan Taubman Health Sciences Library established an EXPERT Research Initiative. This new program is part of the strategic planning for the future of the library and is focused on three primary goals: expanding the library's research portfolio,building librarians' research skills and competencies,and increasing the library's research visibility. The article highlights five library projects that illustrate the different kinds of research collaborations librarians are engaged in with health sciences faculty,researchers,clinicians,and students.展开更多
Purpose: The number of retracted papers from Chinese university-affiliated hospitals is increasing, which has raised much concern. The aim of this study is to analyze the retracted papers from university-affiliated ho...Purpose: The number of retracted papers from Chinese university-affiliated hospitals is increasing, which has raised much concern. The aim of this study is to analyze the retracted papers from university-affiliated hospitals in China’s mainland from 2000 to 2021. Design/methodology/approach: Data for 1,031 retracted papers were identified from the Web of Science Core collection database. The information of the hospitals involved was obtained from their official websites. We analyzed the chronological changes, journal distribution, discipline distribution and retraction reasons for the retracted papers. The grade and geographic locations of the hospitals involved were explored as well.Findings: We found a rapid increase in the number of retracted papers, while the retraction time interval is decreasing. The main reasons for retraction are plagiarism/self-plagiarism(n=255), invalid data/images/conclusions(n=212), fake peer review(n=175) and honesty error(n=163). The disciplines are mainly distributed in oncology(n=320), pharmacology & pharmacy(n=198) and research & experimental medicine(n=166). About 43.8% of the retracted papers were from hospitals affiliated with prestigious universities. Research limitations: This study fails to differentiate between retractions due to honest error and retractions due to research misconduct. We believe that there is a fundamental difference between honest error retractions and misconduct retractions. Another limitation is that authors of the retracted papers have not been analyzed in this study.Practical implications: This study provides a reference for addressing research misconduct in Chinese university-affiliated hospitals. It is our recommendation that universities and hospitals should educate all their staff about the basic norms of research integrity, punish authors of scientific misconduct retracted papers, and reform the unreasonable evaluation system.Originality/value: Based on the analysis of retracted papers, this study further analyzes the characteristics of institutions of retracted papers, which may deepen the research on retracted papers and provide a new perspective to understand the retraction phenomenon.展开更多
基金NSFC(No.71974017)LIS Outstanding Talents Introducing Program,Bureau of Development and Planning of CAS(2022).
文摘Purpose:The notable increase in retraction papers has attracted considerable attention from diverse stakeholders.Various sources are now offering information related to research integrity,including concerns voiced on social media,disclosed lists of paper mills,and retraction notices accessible through journal websites.However,despite the availability of such resources,there remains a lack of a unified platform to consolidate this information,thereby hindering efficient searching and cross-referencing.Thus,it is imperative to develop a comprehensive platform for retracted papers and related concerns.This article aims to introduce“Amend,”a platform designed to integrate information on research integrity from diverse sources.Design/methodology/approach:The Amend platform consolidates concerns and lists of problematic articles sourced from social media platforms(e.g.,PubPeer,For Better Science),retraction notices from journal websites,and citation databases(e.g.,Web of Science,CrossRef).Moreover,Amend includes investigation and punishment announcements released by administrative agencies(e.g.,NSFC,MOE,MOST,CAS).Each related paper is marked and can be traced back to its information source via a provided link.Furthermore,the Amend database incorporates various attributes of retracted articles,including citation topics,funding details,open access status,and more.The reasons for retraction are identified and classified as either academic misconduct or honest errors,with detailed subcategories provided for further clarity.Findings:Within the Amend platform,a total of 32,515 retracted papers indexed in SCI,SSCI,and ESCI between 1980 and 2023 were identified.Of these,26,620(81.87%)were associated with academic misconduct.The retraction rate stands at 6.64 per 10,000 articles.Notably,the retraction rate for non-gold open access articles significantly differs from that for gold open access articles,with this disparity progressively widening over the years.Furthermore,the reasons for retractions have shifted from traditional individual behaviors like falsification,fabrication,plagiarism,and duplication to more organized large-scale fraudulent practices,including Paper Mills,Fake Peer-review,and Artificial Intelligence Generated Content(AIGC).Research limitations:The Amend platform may not fully capture all retracted and concerning papers,thereby impacting its comprehensiveness.Additionally,inaccuracies in retraction notices may lead to errors in tagged reasons.Practical implications:Amend provides an integrated platform for stakeholders to enhance monitoring,analysis,and research on academic misconduct issues.Ultimately,the Amend database can contribute to upholding scientific integrity.Originality/value:This study introduces a globally integrated platform for retracted and concerning papers,along with a preliminary analysis of the evolutionary trends in retracted papers.
文摘Gastric cancer(GC)is a malignant tumor originating from the gastric epithelium,and its incidence and mortality rates rank third among all malignant tumors worldwide.It is also one of the most common cancers in China and is treated predominantly by Western medicine in clinical practice.However,with the advancements in medical technology and informatics,the values of traditional Chinese medicine(TCM)in preventing and treating GC and improving prognosis have increasingly been recognized.According to TCM,clinical manifestations of GC can be divided into Yege(dysphagia),regurgitation,stomach pain,and Zhengxia(abdominal mass).Due to the unbalanced distribution of health care resources in China,most GC patients already have progressive or advanced-stage disease at the first diagnosis.As a result,most GC patients have poor physical function,and surgery or chemotherapy alone will aggravate the impairment to the immune function and seriously affect the quality of life.In contrast,TCM therapies have shown promising efficacy in the management of these patients.Here we review the role of the integrated TCM and Western medicine in treating advanced GC.
文摘The integration of Artificial Intelligence(AI)into healthcare research promises unprecedented advancements in medical diagnostics,treatment personalization,and patient care management.However,these innovations also bring forth significant ethical challenges that must be addressed to maintain public trust,ensure patient safety,and uphold data integrity.This article sets out to introduce a detailed framework designed to steer governance and offer a systematic method for assuring that AI applications in healthcare research are developed and executed with integrity and adherence to medical research ethics.
文摘With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research.
文摘It is imperative that all stakeholders within the research ecosystem take responsibility to improve research integrity and reliability of published research.Based on the unique experiences of a specialist publishing ethics and research integrity team within a major publisher,this article provides insights into the observed trends of misconduct and how those have evolved over time,and addresses key actions needed to improve the interface between researchers,funders,institutions and publishers to collectively improve research integrity on a global scale.
基金This study was supported by the Key Project of the National Natural Science Foundation of China(81830115).
文摘To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care and summarized the available evidence.Pragmatic randomized controlled trials(pRCTs)and clinical registry studies are becoming more popular as they could compensate for the limitations of RCTs.Many RCTs of TCM for cancer treatment as well as systematic reviews have been published.The most investigated therapies are based on acupuncture,Chinese herbal compounds,and Chinese patent medicines.Acupuncture has a significant advantage in relieving cancer-related symptoms.Published studies focus more on improving clinical symptoms and laboratory indicators.However,the patient's quality of life deserves more attention.
文摘Participatory and integrated research approaches employed by a long-term Thai- Vietnamese-German collaborative research program, ‘The Uplands Program’, that address the vicious circles of resource scarcity, environmental degrada- tion and rural poverty in mountainous regions of northern Thailand and northern Vietnam are discussed in this paper. We present two examples from the Thai component of the research program to show how different disciplines and stakeholders need to cooperate at different scales to make meaningful scientific contributions towards sustainable land use and rural development in mountainous regions. The case of resource conservation in the Thai highlands shows that local and scientific knowledge, conven- tional surveys and participatory modeling can be creatively combined. Integrated research on the potential of integrating fruit trees and associated technologies into mountain farming systems suggests that natural scientists have to work alongsideeconomists and social scientists to avoid harmful effects of purely technology-driven and productivity- enhancing approaches. The success of new technologies cannot be measured solely by adoption rates and yield increases, but also needs to take into account their long-term impact on various groups of farmers and the ecological, economic and social trade-offs that they entail. Technical and institutional innovations need to go hand in hand to provide viable livelihood opportunities for smallholder farmers in mountain watersheds. The major lesson learned from the first six years of our research in the mountains of Thailand and Vietnam is that conventional and participatory approaches are not antagonistic; if scientists from various disciplines and research paradigms are open-minded, the combination of both approaches can produce meaningful results that cater for the needs of both the academic community and local stakeholders in mountain environments.
文摘Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunology includes immunological regulation of fertility, materno-fetal immuno-regu-lation, and neuro-reproductive endocrino-immune network. With the integrated traditional Chinese and western medicine (ICWM) applied to reproductive immunology it has been greatly enriched in research contents and depth. The present review is to introduce the recent progresses in research of integrated medicine on reproductive immunology.
基金National Natural Science Foundation of China, No.40601105 Key Project of Science and Technology of Henan Province, No.0721021500
文摘The sediment content of the Yellow River is resulted from the interactions of natural, economic, and social factors, so it includes some evolutive information of the Yellow River Basin system. Sediment contents from 1952 to 2007 on Toudaoguai, Tongguan, Huayuankou and Lijin sections along the river are chosen as the study time series, and correlation dimensions (D2), Kolmogorov entropies (K2), and Hurst indexes (H) of the time series were calculated. Correlation dimensions on Toudaoguai, Tongguan, Huayuankou, and Lijin sections are 3.24, 5.69, 6.57 and 7.34 respectively, and the Kolmogorov entropies are 0.13, 0.37, 0.40 and 0.38 respectively, which indicates that the systems controlled by different sections along the Yellow River are chaotic systems and the chaotic degrees increase gradually from the upper to lower section. The average predictable period of the sediment contents is 8 years on Toudaoguai section and 3 years on the other sections with the reciprocals of the Kolmogorov entropies. The more obvious the chaotic degree is, the shorter the average predictable period is. Hurst indexes on the sections are above 0.5, with the maximum of 0.86 on Tongguan section and the minimum of 0.68 on Toudaoguai section, which indicates that the time series have persistent trends in the average predictable period. Eight state variables and two control parameters are necessary to construct the dynamic model of the Yellow River Basin system.
文摘In order to further clarify the function and important value of the integration of production and education for the development of vocational education,this paper combed the development context of the integration of production and education in China's vocational education from three dimensions:policy evolution,research evolution and practice promotion.Studies have shown that the integration of production and education,as a distinctive type characteristic of vocational education in China,has experienced four stages of evolution in policy:the period of combination of production and education,the preparation and presentation period,the full implementation period and the in-depth promotion period,and the initially-constructed institutional system reflects developmental characteristics.In academic research,there are obvious policy-driven characteristics.The theoretical framework tends to be perfect,and the concept connotation and promotion path are gradually getting clear,but the research on regional promotion modes is slightly insufficient.The empirical research is weak,and the operability of countermeasure research is not strong.Moreover,the problem of discussing integration based on education is more prominent.In practice and promotion,the characteristic of the integration of production and education is gradually highlighted and deepened in terms of talent training,school-running system and school-running mode,and the carriers and contents of the integration of production and education are gradually enriched.
文摘Device physics research for submicron and deep submicron space microelectronics devices and integrated circuits will be described in three topics.1.Thin film submicron and deep submicron SOS / CMOS devices and integrated circuits.2.Deep submicron LDD CMOS devices and integrated circuits.3.C band and Ku band microwave GaAs MESFET and III-V compound hetrojunction HEM T and HBT devices and integrated circuits.
文摘University libraries,as an integral component of university research capabilities,are tasked with serving education by providing research support to faculty and students.This study adopts an affordance research perspective originating from ecological psychology to explore the optimization path of research support services in libraries in the new media era.Based on the characteristics of university library services,this research analyzes three aspects:production affordance,mobile affordance,and social affordance,and proposes practical recommendations to guide future research service practices of university libraries.
文摘The modern history of management systems is almost the same as the history ofmodem management science. Implicit management systems have been in existence for many 100s ofyears. ISO has paid attention to the issue of the integrated management systems since the ISO 9000family standards for quality management systems (QMS) and ISO 14000 series standards for environmentmanagement system (EMS) were published. ISO/TAG (Technical Advisory Group) 12 was formed by theISO/TM (Technical Management Board) in early 1997 with the mandate to achieve greater compatibilitybetween the relevant ISO/TC 176 and ISO/TC 207 standards in the field of management systems,auditing, terms and definitions. The report was submitted to TMB by TAG 12 in 1999.
文摘1.Introduction Surface integrity has great significance for the quality and performance of machined components,and has therefore been increasingly recognized by industry.In particular,within certain industries that require high reliability,such as the aerospace industry,surface integrity is one of the most relevant indexes used to evaluate the quality of machined parts.Thus,obtaining updated knowledge on surface integrity is of great interest to both the academic community and industry[1].
基金Supported by Project of Yunnan Tobacco Company of Science and Technology(2014YN20)
文摘Tobacco black shank is one of the devastating diseases of tobacco. In recent years, this disease widely occurred in most tobacco-growing areas, which caused disastrous losses and has severely threatened the sustainable development of flue-cured tobacco. In order to lay a theoretical foundation for the better control of tobacco black shank, the occurrence characteristics and integrated control strategis of this disease were systematically discussed according to the aspects of agricultural control, chemical control, biological control, etc.
文摘Most research in support of agricultural development and natural resource management in densely settled mountain ecosystems continues to emphasize component over system-level goals. Research by plant breeders, foresters and animal scientists is generally designed to maximize the yield of products within their particular area of expertise (edible plant parts, tree products and livestock products, respectively), while soil scientists aim largely to increase soil nutrient stocks. At landscape level the same dynamic holds within the agronomic sciences, while water engineers work independently to conserve water through its isolation from broader landscape dynamics, and other common property resources remain largely ignored. Opportunities to foster positive synergies between system components, and to integrate livelihood with conservation goals, are generally missed. This paper presents experiences of the African Highlands Initiative, an ecoregional program of the Consultative Group for International Agricultural Research (CGIAR) and a network of the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA), in operationalizing integrated research at farm and landscape scale. Following a discussion of the shortcomings of the conventional research paradigm that beg for strongerintegration and a review of the contributions of extant research paradigms that help us move in the right direction, the paper lays a conceptual foundation for integrated research. System components at farm and landscape level are delineated, and this somewhat arbitrary conceptual partitioning of agroecological systems shown to influence the current research paradigm as well as the partitioning of institutional mandates. Diverse meanings of systems integration are then discussed to illustrate the synergies that might be built into agricultural and natural resource research programs. The distinction between the logic of maximization and optimization is then utilized to distinguish between component and “system-level” goals. This conceptual overview is followed by several case studies to illustrate how these concepts can guide the formulation of integrated research objectives, methods and outputs at farm and landscape scale. The paper concludes with a discussion of the implications of this alternative research paradigm for the structure, function and skill base of national and international agricultural research systems.
基金financially supported by the National Natural Science Foundation of China(81874356)the Open Project of Hubei Key Laboratory of Wudang Local Chinese Medicine Research from Hubei University of Medicine(WDCM2018002,WDCM201917,WDCM201918)+1 种基金the Chinese Medicine Project of Health Commission of Hubei Province(ZY2021010)the Foundation for Innovative Research Team of Hubei University of Medicine(2018YHKT01)。
文摘Primary liver cancer(PLC) is one of the most common malignant tumors in China. PLC is characterized by insidious onset, rapid progress, poor quality of life, and short survival time. Notably, current treatment strategies remain unsatisfactory. Traditional Chinese medicines(TCM) have been used to treat a variety of diseases, including liver diseases, for more than 2000 years. In this study, we performed a review of the use frequency and clinical efficacy of TCM in treating PLC. Relevant literature from January 1, 2009, to January 1, 2021 was retrieved from network databases of China National Knowledge Infrastructure(CNKI), Chongqing VIP, Wanfang, PubMed, and SinoMed. The most frequently used TCM and their efficacy in PLC treatment were summarized. Based on the inclusion and exclusion criteria, 33 articles were selected. Overall, the efficacy of the combination of TCM and Western medicines in the treatment of PLC was higher than that in the control groups(i.e. treatment with Western medicines alone)(65.11% vs.44.31%, P <.05). Among the 33 selected articles, 11 were investigated for TCM preparation(marketed drugs) and 22 for TCM formulas. In total, 102 types of TCM(single herbs) were used to treat PLC. The top five most frequently used TCM were Poria(14.71%), Astragali radix(13.73%), Atractylodis Macrocephalae Rhizoma(12.75%), Bupleuri radix(12.75%), and Glycyrrhizae radix et Rhizoma(11.76%). Of the 102 types of TCM, tonics were the most frequently used categories, followed by heat-clearing medicines, blood-invigorating medicines, and stasis-resolving medicines. Of 207 papers, 174(84.06%) could not be subjected to statistical analysis due to research quality. Further high-quality research on herb sources, formula components and dosage, toxicology, and ethics of TCM is necessary. In conclusion, TCM play a promising role in the treatment and management of PLC, although further investigations are warranted.
文摘This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends in health sciences libraries to increase research skills of librarians in order to foster expanded research integration within the health sciences disciplines,the University of Michigan Taubman Health Sciences Library established an EXPERT Research Initiative. This new program is part of the strategic planning for the future of the library and is focused on three primary goals: expanding the library's research portfolio,building librarians' research skills and competencies,and increasing the library's research visibility. The article highlights five library projects that illustrate the different kinds of research collaborations librarians are engaged in with health sciences faculty,researchers,clinicians,and students.
基金supported by grants from Humanity and Social Science Youth Foundation of Ministry of Education of China (21YJC870016).
文摘Purpose: The number of retracted papers from Chinese university-affiliated hospitals is increasing, which has raised much concern. The aim of this study is to analyze the retracted papers from university-affiliated hospitals in China’s mainland from 2000 to 2021. Design/methodology/approach: Data for 1,031 retracted papers were identified from the Web of Science Core collection database. The information of the hospitals involved was obtained from their official websites. We analyzed the chronological changes, journal distribution, discipline distribution and retraction reasons for the retracted papers. The grade and geographic locations of the hospitals involved were explored as well.Findings: We found a rapid increase in the number of retracted papers, while the retraction time interval is decreasing. The main reasons for retraction are plagiarism/self-plagiarism(n=255), invalid data/images/conclusions(n=212), fake peer review(n=175) and honesty error(n=163). The disciplines are mainly distributed in oncology(n=320), pharmacology & pharmacy(n=198) and research & experimental medicine(n=166). About 43.8% of the retracted papers were from hospitals affiliated with prestigious universities. Research limitations: This study fails to differentiate between retractions due to honest error and retractions due to research misconduct. We believe that there is a fundamental difference between honest error retractions and misconduct retractions. Another limitation is that authors of the retracted papers have not been analyzed in this study.Practical implications: This study provides a reference for addressing research misconduct in Chinese university-affiliated hospitals. It is our recommendation that universities and hospitals should educate all their staff about the basic norms of research integrity, punish authors of scientific misconduct retracted papers, and reform the unreasonable evaluation system.Originality/value: Based on the analysis of retracted papers, this study further analyzes the characteristics of institutions of retracted papers, which may deepen the research on retracted papers and provide a new perspective to understand the retraction phenomenon.