Integrated sensing and communication(ISAC) is considered an effective technique to solve spectrum congestion in the future. In this paper, we consider a hybrid reconfigurable intelligent surface(RIS)-assisted downlink...Integrated sensing and communication(ISAC) is considered an effective technique to solve spectrum congestion in the future. In this paper, we consider a hybrid reconfigurable intelligent surface(RIS)-assisted downlink ISAC system that simultaneously serves multiple single-antenna communication users and senses multiple targets. Hybrid RIS differs from fully passive RIS in that it is composed of both active and passive elements, with the active elements having the effect of amplifying the signal in addition to phase-shifting. We maximize the achievable sum rate of communication users by collaboratively improving the beamforming matrix at the dual function base station(DFBS) and the phase-shifting matrix of the hybrid RIS, subject to the transmit power constraint at the DFBS, the signal-to-interference-plus-noise-ratio(SINR) constraint of the radar echo signal and the RIS constraint are satisfied at the same time. The builtin RIS-assisted ISAC design problem model is significantly non-convex due to the fractional objective function of this optimization problem and the coupling of the optimization variables in the objective function and constraints. As a result, we provide an effective alternating optimization approach based on fractional programming(FP) with block coordinate descent(BCD)to solve the optimization variables. Results from simulations show that the hybrid RIS-assisted ISAC system outperforms the other benchmark solutions.展开更多
Coastal zone is the complex area with intense sea-land interaction. There are various types, complex environments and developed economy in coastal area of China. Under the influence of global change and human activiti...Coastal zone is the complex area with intense sea-land interaction. There are various types, complex environments and developed economy in coastal area of China. Under the influence of global change and human activities, the ecosystem of coastal zone is vulnerable and has sensitive response to environment changes. The environmental problems of sea-level rising have attached close attention by countries all over the world. As far as regions concerned, relative sea-level rising is more important than theoretical sea-level rising. The relative sea-level rising has resulted in series of environment disasters in coastal area of China, such as coastal erosion, seawater invasion, and floods in coastal lowlands, etc. The flux of sediments transported by rivers into sea is the main material source of marine pollution. The human activities are controlling factors of variations in river sediment loads. Under the influence of high strength development in the upstream region, the results are that the reduction of seagoing sediments in main rivers of China, and damage of coastal material balance. Land-based pollution is the main source of marine pollution. With rapid economic development in China s eastern coastal, pollutants flux into sea increase gradually. The results are that the environmental quality and seawater quality of marine have being deteriorated and pollution is serious increasingly. To meet the land demand of industrialization and urbanization, the sea reclamation has become an effective means to alleviate the contradiction between human and land in coastal area of China. This leads to large-scale reduction of coastal wetland area, and the heavy losses of ecological service value of coastal wetland. To face the environmental changes in coastal area of China and solve the contradiction among population, resources, environment, development, it is required to set up the system concept of man-land-sea relationship, so as to achieve sustainable development. The feasible measures include improving coastal management system, strengthening integrated basin management, attaching importance to construction of the coastal environment engineering, and raising the environmental monitoring and early warning level.展开更多
Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding s...Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding scope and intensity of human activity impact,the regional ecological security is facing serious challenges.A scientific assessment of the interrelationship between human activity intensity and habitat quality in the HTRNP is a prerequisite for achieving effective management of ecological disturbances caused by human activities and can also provide scientific strategies for the sustainable development of the region.Based on the land use change data in 2000,2010,and 2020,the spatial and temporal variations and the relationship between habitat quality(HQ)and human activity intensity(HAI)in the HTRNP were explored using the integrated valuation of ecosystem services and trade-offs(InVEST)model.System dynamics and land use simulation models were also combined to conduct multi-scenario simulations of their relationships.The results showed that during 2000–2020,the habitat quality of the HTRNP improved,the intensity of human activities decreased each year,and there was a negative correlation between the two.Second,the system dynamic model could be well coupled with the land use simulation model by combining socio-economic and natural factors.The simulation scenarios of the coupling model showed that the harmonious development(HD)scenario is effective in curbing the increasing trend of human activity intensity and decreasing trend of habitat quality,with a weaker trade-off between the two compared with the baseline development(BD)and investment priority oriented(IPO)scenarios.To maintain the authenticity and integrity of the HTRNP,effective measures such as ecological corridor construction,ecological restoration,and the implementation of ecological compensation policies need to be strengthened.展开更多
The relationship between the earth stress field, earth surface displacement field and the gravity variation is deduced. Algorithms based on the boundary element method to compute the earth stress variation using the e...The relationship between the earth stress field, earth surface displacement field and the gravity variation is deduced. Algorithms based on the boundary element method to compute the earth stress variation using the earth surface displacement is discussed. The stress field variation in Jiashi region, Xinjiang, China is obtained from the GPS data observed in 1997 and 1998, respectively, and the relationship among the local stress field variation, seismic activities and fault tectonic activities is discussed.展开更多
This paper puts forward a model of Pearl River Delta (PRD) fishery in the South China Sea (SCS) that integrates the ecological, social and economic costs and benefits of fisheries activities in a multidisciplinary fra...This paper puts forward a model of Pearl River Delta (PRD) fishery in the South China Sea (SCS) that integrates the ecological, social and economic costs and benefits of fisheries activities in a multidisciplinary framework. In particular, an integrated ECOST model is composed of links between an ecological model constructed by Ecopath with Ecosim (EwE) software and a region Social Accounting Matrix (SAM). Then the costs and benefits of five fishing methods are compared from economic, ecological and social three dimensions base on the ECOST model. The potential effects of fishing effort reduction on fishing communication are explored by a series of dynamic simulations for a 10-year period. Key results from prediction (2005-2015) and policy simulations illustrate that fisheries of PRE are geared toward short-term economic profits at the expense of ecological gains and the whole group of societal benefits associated with fishing. However, the status quo can be improved to better levels by reducing fishing efforts.展开更多
The value of system assimilation is to improve working relationships between tutors and learners while increasing workflow efficiency among tertiary institutions with low operational costs. E-skills could be described...The value of system assimilation is to improve working relationships between tutors and learners while increasing workflow efficiency among tertiary institutions with low operational costs. E-skills could be described as electronic education development, to assist ICT professionals to reach their future career goals and aim to help users boost their ICT skills. In a society that is expanding, it is also a crucial issue to take into account. Researchers have turned their attention to this topic because of its significance and contribution to the empowerment of graduates in digital education. Many scholars have proposed many methods for integrating e-skills into society with impressive results, but the rising rate of graduate unemployment in South Africa is gradually becoming a big worry in our society. A model based on Activity Theory (AT) and e-skills will be developed in our tertiary institution to equip graduates with skills that will increase their employability and provide more individualized work opportunities as part of this study’s effort to solve this issue. With the use of the Statistical Package for the Social Sciences (SPSS) and Cronbach’s Alpha for validity and reliability testing, the study will create an experimental performance to assess the approach taken to measure e-skills in tertiary institutions to empower graduates in South Africa. The study established that system development and e-skilled models for tertiary institutions are growing gradually, especially in South African institutions, that empower graduates with profitable employability with experiences to improve work operation in the industries. In conclusion, system development and e-skills are very demanding but important to empower graduate employability to determine competency in the professional workforce.展开更多
Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process...Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process system"based on IPD(Integrated product development)in the organization.The development stage,process,activity and task are the logical framework elements of the system construction."Based on process decomposition,vertical stratification,horizontal segmentation,combination of special and common,process customized to tools,role and process integration,giving full consideration to the interface between supplier management and process modules"etc.are the concrete ideas.Moreover,formulate top⁃level system construction standards,implemented by process system management tool platform,so that the process system and development work can be effectively integrated to effectively guide the development work of airborne system suppliers,and meet the quality and airworthiness requirements of civil aircraft development.Through the development application of a certain type of flight control system,the process system and tool platform were verified and optimized in practice.展开更多
目的观察疏风活血法治疗糖尿病肾病(DN)A2期风邪证的临床效果。方法筛选60例患者,随机分为对照组及治疗组,各30例。两组患者均给予基础西医治疗,对照组在此基础上给予缬沙坦胶囊口服,治疗组给予缬沙坦胶囊口服+疏风活肾颗粒剂治疗。观...目的观察疏风活血法治疗糖尿病肾病(DN)A2期风邪证的临床效果。方法筛选60例患者,随机分为对照组及治疗组,各30例。两组患者均给予基础西医治疗,对照组在此基础上给予缬沙坦胶囊口服,治疗组给予缬沙坦胶囊口服+疏风活肾颗粒剂治疗。观察治疗前后两组尿微量白蛋白(mALB)、24 h尿蛋白定量(24 h UP)、血浆胱抑素-C(Cys-C)、肾小球滤过率(eGFR)的改善情况及临床疗效。结果治疗组的总有效率为86.7%(26/30),高于对照组的63.3%(19/30)(P<0.05)。治疗后,治疗组中医证候总积分优于对照组(P<0.05);两组患者mALB、24 h UP、Cys-C、eGFR显著改善,且治疗组各指标改善情况均优于对照组(P<0.05)。结论在常规西医治疗方法的基础上应用疏风活血方治疗DN A2期风邪证,对于进一步改善患者肾功能具有重要作用。展开更多
A wideband monolithic optoelectronic integrated receiver with a high-speed photo-detector,completely compatible with standard CMOS processes,is designed and implemented in 0.6μm standard CMOS technology.The experimen...A wideband monolithic optoelectronic integrated receiver with a high-speed photo-detector,completely compatible with standard CMOS processes,is designed and implemented in 0.6μm standard CMOS technology.The experimental results demonstrate that its performance approaches applicable requirements,where the photo-detector achieves a -3dB frequency of 1.11GHz,and the receiver achieves a 3dB bandwidth of 733MHz and a sensitivity of -9dBm for λ=850nm at BER=10-12.展开更多
Based on an avalanche photodiode( APD) detecting array working in Geiger mode( GM-APD), a high-performance infrared sensor readout integrated circuit( ROIC) used for infrared 3D( three-dimensional) imaging is ...Based on an avalanche photodiode( APD) detecting array working in Geiger mode( GM-APD), a high-performance infrared sensor readout integrated circuit( ROIC) used for infrared 3D( three-dimensional) imaging is proposed. The system mainly consists of three functional modules, including active quenching circuit( AQC), time-to-digital converter( TDC) circuit and other timing controller circuit. Each AQC and TDC circuit together constitutes the pixel circuit. Under the cooperation with other modules, the current signal generated by the GM-APD sensor is detected by the AQC, and the photon time-of-flight( TOF) is measured and converted to a digital signal output to achieve a better noise suppression and a higher detection sensitivity by the TDC. The ROIC circuit is fabricated by the CSMC 0. 5 μm standard CMOS technology. The array size is 8 × 8, and the center distance of two adjacent cells is 100μm. The measurement results of the chip showthat the performance of the circuit is good, and the chip can achieve 1 ns time resolution with a 250 MHz reference clock, and the circuit can be used in the array structure of the infrared detection system or focal plane array( FPA).展开更多
Aeolian deposits from the deserts in northern China have been used for palaeoenvironmental research to understand aeolian sedimentology and its dynamic connection to past climate conditions. The Tengger Desert in Chin...Aeolian deposits from the deserts in northern China have been used for palaeoenvironmental research to understand aeolian sedimentology and its dynamic connection to past climate conditions. The Tengger Desert in China is sensitive to the waxing and waning of the monsoonal system. In response to past climate change, the southern margin of the Tengger Desert has evolved significantly since the last glacial period. However, previous attempts to date aeolian deposits in this region were mainly based on radiocarbon dating, which has problems when applied to aeolian deposits. Moreover, sedimentary records are limited. Accordingly, past aeolian activity in this desert remains poorly understood. In the present study, we dated sand samples from Gulang county at the southern margin of the Tengger Desert using optically stimulated luminescence (OSL) to understand the history of aeolian activity in this region. Our samples represented well-sorted aeolian sands and sandy loess. Aeolian sands are evidence of dune field buildup and sparse vegetation cover whereas sandy loess is evidence of improved stabilization of sand dunes resulting from ameliorated vegetation cover. Certain samples showed a decline in the equivalent dose (D<sub> e </sub>) values when successive integration intervals were applied, which resulted from unstable OSL signals from non-fast components in the initial part of the decay curve. In order to obtain reliable D<sub> e </sub> estimates, we investigated component-resolved and different background subtraction approaches, and compared the resultant D<sub> e </sub> estimates. We adopted the early background subtraction method to derive D<sub> e </sub> values. Luminescence chronologies and sedimentary records indicated that sand dunes accumulation occurred before 10 ka, and sandy loess developed between 9.5 and 7.6 ka when sand dunes were stabilized as a result of increased effective moisture levels. The transition between sand dune mobilization and stabilization emphasizes the significance of an effective moisture threshold in controlling aeolian activity. Mobilization of sand dunes at ~2.3 ka might be related to an increased aridity during the Late Holocene.展开更多
Microbial translocation is a cause of systemic immune activation in HIV/SIV infection. In the present study, we found a lower CD8+ T cell activation level in Macaca leonina (northern pig-tailed macaques, NPMs) than in...Microbial translocation is a cause of systemic immune activation in HIV/SIV infection. In the present study, we found a lower CD8+ T cell activation level in Macaca leonina (northern pig-tailed macaques, NPMs) than in Macaca mulatta (Chinese rhesus macaques, ChRMs) during SIVmac239 infection. Furthermore, the levels of plasma LPS-binding protein and soluble CD14 in NPMs were lower than those in ChRMs. Compared with ChRMs, SIV-infected NPMs had lower Chiu scores, representing relatively normal intestinal mucosa. In addition, no obvious damage to the ileum or colon epithelial barrier was observed in either infected or uninfected NPMs, which differed to that found in ChRMs. Furthermore, no significant microbial translocation (Escherichia coli) was detected in the colon or ileum of infected or uninfected NPMs, which again differed to that observed in ChRMs. In conclusion, NPMs retained superior intestinal integrity and limited microbial translocation during SIV infection, which may contribute to their lower immune activation compared with ChRMs.展开更多
In order to guarantee safety and stability during physical human-robot-interaction(p HRI) in the occasion of service or industrial operation, a serial integrated rotary joint with the characteristics of passive and ac...In order to guarantee safety and stability during physical human-robot-interaction(p HRI) in the occasion of service or industrial operation, a serial integrated rotary joint with the characteristics of passive and active compliance is proposed. Passive compliance is achieved by a designed elastic element, such that the compliant joint may minimize large force which occurs during accidental impacts and, further, may offer more accurate and stable force control and a capacity for energy storage. Meanwhile, the modeling of the compliant joint is comprehensively analyzed, including the effect of the motor model on the overall control system. In order to realize the active compliance, a new method of impedance control is proposed. On the basis of PD control, a more compliant impedance controller is introduced. Experimental results show that the serial integrated rotary joint can provide more effective safety compliance during physical interaction, which has also been well applied in our designed massage robot and rehabilitation robot.展开更多
Drinking water is supplied through a centralized water supply system and may not be accessed by communities in rural areas of Malaysia.This study investigated the performance of a low-cost, self-prepared combined acti...Drinking water is supplied through a centralized water supply system and may not be accessed by communities in rural areas of Malaysia.This study investigated the performance of a low-cost, self-prepared combined activated carbon and sand filtration(CACSF) system for roofharvested rainwater and lake water for potable use. Activated carbon was self-prepared using locally sourced coconut shell and was activated using commonly available salt rather than a high-tech procedure that requires a chemical reagent. The filtration chamber was comprised of local,readily available sand. The experiments were conducted with varying antecedent dry intervals(ADIs) of up to 15 d and lake water with varying initial chemical oxygen demand(COD) concentration. The CACSF system managed to produce effluents complying with the drinking water standards for the parameters p H, dissolved oxygen(DO), biochemical oxygen demand(BOD5), COD, total suspended solids(TSS), and ammonia nitrogen(NH_3-N). The CACSF system successfully decreased the population of Escherichia coli(E. coli) in the influents to less than 30 CFU/m L. Samples with a higher population of E. coli(that is, greater than 30 CFU/m L) did not show 100% removal. The system also showed high potential as an alternative for treated drinking water for roof-harvested rainwater and class II lake water.展开更多
文摘Integrated sensing and communication(ISAC) is considered an effective technique to solve spectrum congestion in the future. In this paper, we consider a hybrid reconfigurable intelligent surface(RIS)-assisted downlink ISAC system that simultaneously serves multiple single-antenna communication users and senses multiple targets. Hybrid RIS differs from fully passive RIS in that it is composed of both active and passive elements, with the active elements having the effect of amplifying the signal in addition to phase-shifting. We maximize the achievable sum rate of communication users by collaboratively improving the beamforming matrix at the dual function base station(DFBS) and the phase-shifting matrix of the hybrid RIS, subject to the transmit power constraint at the DFBS, the signal-to-interference-plus-noise-ratio(SINR) constraint of the radar echo signal and the RIS constraint are satisfied at the same time. The builtin RIS-assisted ISAC design problem model is significantly non-convex due to the fractional objective function of this optimization problem and the coupling of the optimization variables in the objective function and constraints. As a result, we provide an effective alternating optimization approach based on fractional programming(FP) with block coordinate descent(BCD)to solve the optimization variables. Results from simulations show that the hybrid RIS-assisted ISAC system outperforms the other benchmark solutions.
基金Supported by National Natural Science Foundation of China(Grant No.:41501003,41701101 41807403)Open Foundation of Research Institute of Jiangsu Coastal Development(Grant No.:RIJCD11008)
文摘Coastal zone is the complex area with intense sea-land interaction. There are various types, complex environments and developed economy in coastal area of China. Under the influence of global change and human activities, the ecosystem of coastal zone is vulnerable and has sensitive response to environment changes. The environmental problems of sea-level rising have attached close attention by countries all over the world. As far as regions concerned, relative sea-level rising is more important than theoretical sea-level rising. The relative sea-level rising has resulted in series of environment disasters in coastal area of China, such as coastal erosion, seawater invasion, and floods in coastal lowlands, etc. The flux of sediments transported by rivers into sea is the main material source of marine pollution. The human activities are controlling factors of variations in river sediment loads. Under the influence of high strength development in the upstream region, the results are that the reduction of seagoing sediments in main rivers of China, and damage of coastal material balance. Land-based pollution is the main source of marine pollution. With rapid economic development in China s eastern coastal, pollutants flux into sea increase gradually. The results are that the environmental quality and seawater quality of marine have being deteriorated and pollution is serious increasingly. To meet the land demand of industrialization and urbanization, the sea reclamation has become an effective means to alleviate the contradiction between human and land in coastal area of China. This leads to large-scale reduction of coastal wetland area, and the heavy losses of ecological service value of coastal wetland. To face the environmental changes in coastal area of China and solve the contradiction among population, resources, environment, development, it is required to set up the system concept of man-land-sea relationship, so as to achieve sustainable development. The feasible measures include improving coastal management system, strengthening integrated basin management, attaching importance to construction of the coastal environment engineering, and raising the environmental monitoring and early warning level.
基金Under the auspices of the National Social Science Found of China(No.21XGL019)Hainan Provincial Natural Science Foundation of China(No.421RC1034)Professor/Doctor Research Foundation of Huizhou University(No.2022JB080)。
文摘Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding scope and intensity of human activity impact,the regional ecological security is facing serious challenges.A scientific assessment of the interrelationship between human activity intensity and habitat quality in the HTRNP is a prerequisite for achieving effective management of ecological disturbances caused by human activities and can also provide scientific strategies for the sustainable development of the region.Based on the land use change data in 2000,2010,and 2020,the spatial and temporal variations and the relationship between habitat quality(HQ)and human activity intensity(HAI)in the HTRNP were explored using the integrated valuation of ecosystem services and trade-offs(InVEST)model.System dynamics and land use simulation models were also combined to conduct multi-scenario simulations of their relationships.The results showed that during 2000–2020,the habitat quality of the HTRNP improved,the intensity of human activities decreased each year,and there was a negative correlation between the two.Second,the system dynamic model could be well coupled with the land use simulation model by combining socio-economic and natural factors.The simulation scenarios of the coupling model showed that the harmonious development(HD)scenario is effective in curbing the increasing trend of human activity intensity and decreasing trend of habitat quality,with a weaker trade-off between the two compared with the baseline development(BD)and investment priority oriented(IPO)scenarios.To maintain the authenticity and integrity of the HTRNP,effective measures such as ecological corridor construction,ecological restoration,and the implementation of ecological compensation policies need to be strengthened.
基金State Natural Science Foundation of China !(49774214)the State Key Project !(96-913-07).
文摘The relationship between the earth stress field, earth surface displacement field and the gravity variation is deduced. Algorithms based on the boundary element method to compute the earth stress variation using the earth surface displacement is discussed. The stress field variation in Jiashi region, Xinjiang, China is obtained from the GPS data observed in 1997 and 1998, respectively, and the relationship among the local stress field variation, seismic activities and fault tectonic activities is discussed.
文摘This paper puts forward a model of Pearl River Delta (PRD) fishery in the South China Sea (SCS) that integrates the ecological, social and economic costs and benefits of fisheries activities in a multidisciplinary framework. In particular, an integrated ECOST model is composed of links between an ecological model constructed by Ecopath with Ecosim (EwE) software and a region Social Accounting Matrix (SAM). Then the costs and benefits of five fishing methods are compared from economic, ecological and social three dimensions base on the ECOST model. The potential effects of fishing effort reduction on fishing communication are explored by a series of dynamic simulations for a 10-year period. Key results from prediction (2005-2015) and policy simulations illustrate that fisheries of PRE are geared toward short-term economic profits at the expense of ecological gains and the whole group of societal benefits associated with fishing. However, the status quo can be improved to better levels by reducing fishing efforts.
文摘The value of system assimilation is to improve working relationships between tutors and learners while increasing workflow efficiency among tertiary institutions with low operational costs. E-skills could be described as electronic education development, to assist ICT professionals to reach their future career goals and aim to help users boost their ICT skills. In a society that is expanding, it is also a crucial issue to take into account. Researchers have turned their attention to this topic because of its significance and contribution to the empowerment of graduates in digital education. Many scholars have proposed many methods for integrating e-skills into society with impressive results, but the rising rate of graduate unemployment in South Africa is gradually becoming a big worry in our society. A model based on Activity Theory (AT) and e-skills will be developed in our tertiary institution to equip graduates with skills that will increase their employability and provide more individualized work opportunities as part of this study’s effort to solve this issue. With the use of the Statistical Package for the Social Sciences (SPSS) and Cronbach’s Alpha for validity and reliability testing, the study will create an experimental performance to assess the approach taken to measure e-skills in tertiary institutions to empower graduates in South Africa. The study established that system development and e-skilled models for tertiary institutions are growing gradually, especially in South African institutions, that empower graduates with profitable employability with experiences to improve work operation in the industries. In conclusion, system development and e-skills are very demanding but important to empower graduate employability to determine competency in the professional workforce.
文摘Based on the analysis of the development process system status of domestic and foreign civil aircraft airborne system suppliers,this paper proposes the overall construction idea of"a set of civil aircraft process system"based on IPD(Integrated product development)in the organization.The development stage,process,activity and task are the logical framework elements of the system construction."Based on process decomposition,vertical stratification,horizontal segmentation,combination of special and common,process customized to tools,role and process integration,giving full consideration to the interface between supplier management and process modules"etc.are the concrete ideas.Moreover,formulate top⁃level system construction standards,implemented by process system management tool platform,so that the process system and development work can be effectively integrated to effectively guide the development work of airborne system suppliers,and meet the quality and airworthiness requirements of civil aircraft development.Through the development application of a certain type of flight control system,the process system and tool platform were verified and optimized in practice.
文摘目的观察疏风活血法治疗糖尿病肾病(DN)A2期风邪证的临床效果。方法筛选60例患者,随机分为对照组及治疗组,各30例。两组患者均给予基础西医治疗,对照组在此基础上给予缬沙坦胶囊口服,治疗组给予缬沙坦胶囊口服+疏风活肾颗粒剂治疗。观察治疗前后两组尿微量白蛋白(mALB)、24 h尿蛋白定量(24 h UP)、血浆胱抑素-C(Cys-C)、肾小球滤过率(eGFR)的改善情况及临床疗效。结果治疗组的总有效率为86.7%(26/30),高于对照组的63.3%(19/30)(P<0.05)。治疗后,治疗组中医证候总积分优于对照组(P<0.05);两组患者mALB、24 h UP、Cys-C、eGFR显著改善,且治疗组各指标改善情况均优于对照组(P<0.05)。结论在常规西医治疗方法的基础上应用疏风活血方治疗DN A2期风邪证,对于进一步改善患者肾功能具有重要作用。
文摘A wideband monolithic optoelectronic integrated receiver with a high-speed photo-detector,completely compatible with standard CMOS processes,is designed and implemented in 0.6μm standard CMOS technology.The experimental results demonstrate that its performance approaches applicable requirements,where the photo-detector achieves a -3dB frequency of 1.11GHz,and the receiver achieves a 3dB bandwidth of 733MHz and a sensitivity of -9dBm for λ=850nm at BER=10-12.
基金The Natural Science Foundation of Jiangsu Province(No.BK2012559)Qing Lan Project of Jiangsu Province
文摘Based on an avalanche photodiode( APD) detecting array working in Geiger mode( GM-APD), a high-performance infrared sensor readout integrated circuit( ROIC) used for infrared 3D( three-dimensional) imaging is proposed. The system mainly consists of three functional modules, including active quenching circuit( AQC), time-to-digital converter( TDC) circuit and other timing controller circuit. Each AQC and TDC circuit together constitutes the pixel circuit. Under the cooperation with other modules, the current signal generated by the GM-APD sensor is detected by the AQC, and the photon time-of-flight( TOF) is measured and converted to a digital signal output to achieve a better noise suppression and a higher detection sensitivity by the TDC. The ROIC circuit is fabricated by the CSMC 0. 5 μm standard CMOS technology. The array size is 8 × 8, and the center distance of two adjacent cells is 100μm. The measurement results of the chip showthat the performance of the circuit is good, and the chip can achieve 1 ns time resolution with a 250 MHz reference clock, and the circuit can be used in the array structure of the infrared detection system or focal plane array( FPA).
基金funded by the National Basic Research Program of China(2013CB956000,2012CB426501)
文摘Aeolian deposits from the deserts in northern China have been used for palaeoenvironmental research to understand aeolian sedimentology and its dynamic connection to past climate conditions. The Tengger Desert in China is sensitive to the waxing and waning of the monsoonal system. In response to past climate change, the southern margin of the Tengger Desert has evolved significantly since the last glacial period. However, previous attempts to date aeolian deposits in this region were mainly based on radiocarbon dating, which has problems when applied to aeolian deposits. Moreover, sedimentary records are limited. Accordingly, past aeolian activity in this desert remains poorly understood. In the present study, we dated sand samples from Gulang county at the southern margin of the Tengger Desert using optically stimulated luminescence (OSL) to understand the history of aeolian activity in this region. Our samples represented well-sorted aeolian sands and sandy loess. Aeolian sands are evidence of dune field buildup and sparse vegetation cover whereas sandy loess is evidence of improved stabilization of sand dunes resulting from ameliorated vegetation cover. Certain samples showed a decline in the equivalent dose (D<sub> e </sub>) values when successive integration intervals were applied, which resulted from unstable OSL signals from non-fast components in the initial part of the decay curve. In order to obtain reliable D<sub> e </sub> estimates, we investigated component-resolved and different background subtraction approaches, and compared the resultant D<sub> e </sub> estimates. We adopted the early background subtraction method to derive D<sub> e </sub> values. Luminescence chronologies and sedimentary records indicated that sand dunes accumulation occurred before 10 ka, and sandy loess developed between 9.5 and 7.6 ka when sand dunes were stabilized as a result of increased effective moisture levels. The transition between sand dune mobilization and stabilization emphasizes the significance of an effective moisture threshold in controlling aeolian activity. Mobilization of sand dunes at ~2.3 ka might be related to an increased aridity during the Late Holocene.
基金partly supported by grants from the National Natural Science Foundation of China(U1802284 81471620,81671627,81771770,81571606)+1 种基金13th Five-Year Key Scientific and Technological Program of China(2017ZX10304402-002-004,2017ZX10202102-001-005,2018ZX10301101-002-003,2018ZX10301406-003)Knowledge Innovation Program of the Chinese Academy of Sciences(ZDRW-ZS-2016-4)
文摘Microbial translocation is a cause of systemic immune activation in HIV/SIV infection. In the present study, we found a lower CD8+ T cell activation level in Macaca leonina (northern pig-tailed macaques, NPMs) than in Macaca mulatta (Chinese rhesus macaques, ChRMs) during SIVmac239 infection. Furthermore, the levels of plasma LPS-binding protein and soluble CD14 in NPMs were lower than those in ChRMs. Compared with ChRMs, SIV-infected NPMs had lower Chiu scores, representing relatively normal intestinal mucosa. In addition, no obvious damage to the ileum or colon epithelial barrier was observed in either infected or uninfected NPMs, which differed to that found in ChRMs. Furthermore, no significant microbial translocation (Escherichia coli) was detected in the colon or ileum of infected or uninfected NPMs, which again differed to that observed in ChRMs. In conclusion, NPMs retained superior intestinal integrity and limited microbial translocation during SIV infection, which may contribute to their lower immune activation compared with ChRMs.
基金Project(81473694)supported by the National Natural Science Foundation of ChinaProject(2016A1027)supported by the major Project of Zhongshan City,ChinaProject(2016FZFC007)supported by the Intelligent Equipment and Technology of Automation Research and Development Platform,China
文摘In order to guarantee safety and stability during physical human-robot-interaction(p HRI) in the occasion of service or industrial operation, a serial integrated rotary joint with the characteristics of passive and active compliance is proposed. Passive compliance is achieved by a designed elastic element, such that the compliant joint may minimize large force which occurs during accidental impacts and, further, may offer more accurate and stable force control and a capacity for energy storage. Meanwhile, the modeling of the compliant joint is comprehensively analyzed, including the effect of the motor model on the overall control system. In order to realize the active compliance, a new method of impedance control is proposed. On the basis of PD control, a more compliant impedance controller is introduced. Experimental results show that the serial integrated rotary joint can provide more effective safety compliance during physical interaction, which has also been well applied in our designed massage robot and rehabilitation robot.
基金supported by the Universiti Kebangsaan Malaysia Grant(Grant No.GUP-2014-077)
文摘Drinking water is supplied through a centralized water supply system and may not be accessed by communities in rural areas of Malaysia.This study investigated the performance of a low-cost, self-prepared combined activated carbon and sand filtration(CACSF) system for roofharvested rainwater and lake water for potable use. Activated carbon was self-prepared using locally sourced coconut shell and was activated using commonly available salt rather than a high-tech procedure that requires a chemical reagent. The filtration chamber was comprised of local,readily available sand. The experiments were conducted with varying antecedent dry intervals(ADIs) of up to 15 d and lake water with varying initial chemical oxygen demand(COD) concentration. The CACSF system managed to produce effluents complying with the drinking water standards for the parameters p H, dissolved oxygen(DO), biochemical oxygen demand(BOD5), COD, total suspended solids(TSS), and ammonia nitrogen(NH_3-N). The CACSF system successfully decreased the population of Escherichia coli(E. coli) in the influents to less than 30 CFU/m L. Samples with a higher population of E. coli(that is, greater than 30 CFU/m L) did not show 100% removal. The system also showed high potential as an alternative for treated drinking water for roof-harvested rainwater and class II lake water.