Lennie Lighthouse is written by Paul Jennings, who is an English-born Australian childrenbook writer. His books mainly focus on short stories whichcould lead the reader into an unusual series of events that ended with...Lennie Lighthouse is written by Paul Jennings, who is an English-born Australian childrenbook writer. His books mainly focus on short stories whichcould lead the reader into an unusual series of events that ended with a twist. Now Paul Jennings has achieved a great success and has became a well-known children's book writer. In this paper, the stylistic features and the narrative structurein"Lennie Lighthouse"would be analyzed based on Labov's narrative model, especially the external evaluations and internal evaluationsin the story.Finally it intended to explore that how the children story could attract such a diverse group of readers and the structure of this legendary story would be deduced and writing stylewould be analyzed in this paper.展开更多
Colon cancer continues to be one of the leading causes of mortality and morbidity throughout the world despite the availability of reliable screening tools and effective therapies.The majority of patients with colon c...Colon cancer continues to be one of the leading causes of mortality and morbidity throughout the world despite the availability of reliable screening tools and effective therapies.The majority of patients with colon cancer are diagnosed at an early stage(stages I to III),which provides an opportunity for cure.The current treatment paradigm of early stage colon cancer consists of surgery followed by adjuvant chemotherapy in a select group of patients,which is directed at the eradication of minimal residual disease to achieve a cure.Surgery alone is curative for the vast majority of colon cancer patients.Currently,surgery and adjuvant chemotherapy can achieve long term survival in about two-thirds of colon cancer patients with nodal involvement.Adjuvant chemotherapy is recommended for all patients with stage III colon cancer,while the benefit in stage II patients is not unequivocally established despite several large clinical trials.Contemporary research in early stage colon cancer is focused on minimally invasive surgical techniques,strategies to limit treatment-related toxicities,precise patient selection for adjuvant therapy,utilization of molecular and clinicopathologic information to personalize therapy and exploration of new therapies exploiting the evolving knowledge of tumor biology.In this review,we will discuss the current standard treatment,evolving treatment paradigms,and the emerging biomarkers,that will likely help improve patient selection and personalization of therapy leading to superior outcomes.展开更多
In order to better promote the development of diecasting industry in our country, to boost the application of new diecasting technology and techniques, to improve the competitive power of the diecasting enterprises in...In order to better promote the development of diecasting industry in our country, to boost the application of new diecasting technology and techniques, to improve the competitive power of the diecasting enterprises in our country, to extend the international markets and to improve qualities of diecastings more quickly, the activity of evaluating high quality diecastings was organized by Foundry Institution of Chinese Mechanical Engineering Society (FICMES) during the period of the 5th China International Diecasting Congress & Exhibition. The Excellent Diecastings Evaluation Committee was composed of an independent panel of experts in China’s diecasting industry. In accordance with the evaluation rules of impersonality and impartiality, the Evaluation Committee members, at the site of the exhibition, carefully checked each and all evaluation indexes of the diecastings accepted in the activity, deliberately examined the real diecastings, and inquired of the technicians of the companies taking part in the evaluation activity about the production processes, qualities and other information of the diecastings. After discussion again and again, finally, five diecastings were entitled as the excellent diecastings of the 5th China International Diecasting Conference & Exhibition. They are listed as follows: 1. Shell of PC notebook produced by Ka Shui Manufactory Co., Ltd., Shenzhen, Guangdong, material: magnesium alloy AZ91D. 2. Base of mobile telecom transmitter produced by Guangdong Gaoyao G-ACE Casting Technology Co., Ltd, material: ADC12. 3. Flywheel casing (for Renault trucks) produced by Shanghai Cosmopolitan Automobile Accessory Co., Ltd, material: A380. 4. Strainer case (for Japan Isuzu automobiles) produced by Guangdong Wencan Die Casting Co., Ltd, material: ADC12. 5. Intake manifold of six-cylinder diesel engine. produced by Jinan Huicheng Foundry Co., Ltd, material: AlSi9Cu3.展开更多
Global urbanization is exerting severe stress and having far-reaching impacts on the eco-environment, and yet there exists a complex non-linear coupling relationship between the two. Research on the interactive coupli...Global urbanization is exerting severe stress and having far-reaching impacts on the eco-environment, and yet there exists a complex non-linear coupling relationship between the two. Research on the interactive coupling effect between urbanization and the eco-environment will be a popular area of study and frontier in international earth system science and sustainability science in the next 10 years, while also being a high-priority research topic of particular interest to international organizations. This paper systematically collates and summarizes the international progress made in research on interactive coupling theory, coupling relationships, coupling mechanisms, coupling laws, coupling thresholds, coupling models and coupling optimization decision support systems. The research shows that urbanization and eco-environment interactive coupling theories include the Kuznets curve theory, telecoupling theory, planetary boundaries theory, footprint family theory and urban metabolism theory; most research on interactive coupling relationships is concerned with single- element coupling relationships, such as those between urbanization and water, land, atmosphere, climate change, ecosystems and biodiversity; the majority of research on interactive coupling mechanisms and laws focuses on five research paradigms, including coupled human and nature systems, complex social-ecological systems, urban ecosystems, social-economic-natural complex ecosystems, and urbanization development and eco-environment constraint ring; the majority of interactive coupling simulations use STIRPAT models, coupling degree models, multi-agent system models and big data urban computer models; and research has been carried out on urbanization and eco-environment coupling thresholds, coercing risk and optimal decision support systems. An objective evaluation of progress in international research on interactive coupling between urbanization and the eco-environment suggests that there are six main research focal points and six areas lacking research: a lot of research exists on macroscopic coupling effects, with little research on urban agglomeration and scale coupling effects; considerable research exists on sin-gle-dimension coupling effects, with little on multiple-dimension coupling effects; a great deal exists on "one-to-one" dual- element coupling effects, with little on "many-to-many" multiple-element coupling effects; a lot exists on positive feedback coupling effects, and little on negative feedback coupling effects; a great deal exists on empirical coupling effects, and little on theoretical coupling effects; a great deal exists on the use of simple quantitative methods, and little on using integrated simulation methods. Future studies should focus on coupling effects between urbanization in urban agglomerations and the eco-environment, spatial scale coupling effects, multi-dimensional coupling effects, telecoupling effects, "one-to-many" and "many-to-many" element coupling effects, and positive and negative feedback coupling effects. There is also a need to strengthen the development and application of dynamic models for multi-element,-scale,-scenario,-module and-agent integrated spatiotemporal coupling systems and further improve theoretical innovations in coupling effect research and integrate and form complete and diverse coupling theoretical systems.展开更多
文摘Lennie Lighthouse is written by Paul Jennings, who is an English-born Australian childrenbook writer. His books mainly focus on short stories whichcould lead the reader into an unusual series of events that ended with a twist. Now Paul Jennings has achieved a great success and has became a well-known children's book writer. In this paper, the stylistic features and the narrative structurein"Lennie Lighthouse"would be analyzed based on Labov's narrative model, especially the external evaluations and internal evaluationsin the story.Finally it intended to explore that how the children story could attract such a diverse group of readers and the structure of this legendary story would be deduced and writing stylewould be analyzed in this paper.
文摘Colon cancer continues to be one of the leading causes of mortality and morbidity throughout the world despite the availability of reliable screening tools and effective therapies.The majority of patients with colon cancer are diagnosed at an early stage(stages I to III),which provides an opportunity for cure.The current treatment paradigm of early stage colon cancer consists of surgery followed by adjuvant chemotherapy in a select group of patients,which is directed at the eradication of minimal residual disease to achieve a cure.Surgery alone is curative for the vast majority of colon cancer patients.Currently,surgery and adjuvant chemotherapy can achieve long term survival in about two-thirds of colon cancer patients with nodal involvement.Adjuvant chemotherapy is recommended for all patients with stage III colon cancer,while the benefit in stage II patients is not unequivocally established despite several large clinical trials.Contemporary research in early stage colon cancer is focused on minimally invasive surgical techniques,strategies to limit treatment-related toxicities,precise patient selection for adjuvant therapy,utilization of molecular and clinicopathologic information to personalize therapy and exploration of new therapies exploiting the evolving knowledge of tumor biology.In this review,we will discuss the current standard treatment,evolving treatment paradigms,and the emerging biomarkers,that will likely help improve patient selection and personalization of therapy leading to superior outcomes.
文摘In order to better promote the development of diecasting industry in our country, to boost the application of new diecasting technology and techniques, to improve the competitive power of the diecasting enterprises in our country, to extend the international markets and to improve qualities of diecastings more quickly, the activity of evaluating high quality diecastings was organized by Foundry Institution of Chinese Mechanical Engineering Society (FICMES) during the period of the 5th China International Diecasting Congress & Exhibition. The Excellent Diecastings Evaluation Committee was composed of an independent panel of experts in China’s diecasting industry. In accordance with the evaluation rules of impersonality and impartiality, the Evaluation Committee members, at the site of the exhibition, carefully checked each and all evaluation indexes of the diecastings accepted in the activity, deliberately examined the real diecastings, and inquired of the technicians of the companies taking part in the evaluation activity about the production processes, qualities and other information of the diecastings. After discussion again and again, finally, five diecastings were entitled as the excellent diecastings of the 5th China International Diecasting Conference & Exhibition. They are listed as follows: 1. Shell of PC notebook produced by Ka Shui Manufactory Co., Ltd., Shenzhen, Guangdong, material: magnesium alloy AZ91D. 2. Base of mobile telecom transmitter produced by Guangdong Gaoyao G-ACE Casting Technology Co., Ltd, material: ADC12. 3. Flywheel casing (for Renault trucks) produced by Shanghai Cosmopolitan Automobile Accessory Co., Ltd, material: A380. 4. Strainer case (for Japan Isuzu automobiles) produced by Guangdong Wencan Die Casting Co., Ltd, material: ADC12. 5. Intake manifold of six-cylinder diesel engine. produced by Jinan Huicheng Foundry Co., Ltd, material: AlSi9Cu3.
基金Major Program of the National Natural Science Foundation of China,No.41590840,No.41590842
文摘Global urbanization is exerting severe stress and having far-reaching impacts on the eco-environment, and yet there exists a complex non-linear coupling relationship between the two. Research on the interactive coupling effect between urbanization and the eco-environment will be a popular area of study and frontier in international earth system science and sustainability science in the next 10 years, while also being a high-priority research topic of particular interest to international organizations. This paper systematically collates and summarizes the international progress made in research on interactive coupling theory, coupling relationships, coupling mechanisms, coupling laws, coupling thresholds, coupling models and coupling optimization decision support systems. The research shows that urbanization and eco-environment interactive coupling theories include the Kuznets curve theory, telecoupling theory, planetary boundaries theory, footprint family theory and urban metabolism theory; most research on interactive coupling relationships is concerned with single- element coupling relationships, such as those between urbanization and water, land, atmosphere, climate change, ecosystems and biodiversity; the majority of research on interactive coupling mechanisms and laws focuses on five research paradigms, including coupled human and nature systems, complex social-ecological systems, urban ecosystems, social-economic-natural complex ecosystems, and urbanization development and eco-environment constraint ring; the majority of interactive coupling simulations use STIRPAT models, coupling degree models, multi-agent system models and big data urban computer models; and research has been carried out on urbanization and eco-environment coupling thresholds, coercing risk and optimal decision support systems. An objective evaluation of progress in international research on interactive coupling between urbanization and the eco-environment suggests that there are six main research focal points and six areas lacking research: a lot of research exists on macroscopic coupling effects, with little research on urban agglomeration and scale coupling effects; considerable research exists on sin-gle-dimension coupling effects, with little on multiple-dimension coupling effects; a great deal exists on "one-to-one" dual- element coupling effects, with little on "many-to-many" multiple-element coupling effects; a lot exists on positive feedback coupling effects, and little on negative feedback coupling effects; a great deal exists on empirical coupling effects, and little on theoretical coupling effects; a great deal exists on the use of simple quantitative methods, and little on using integrated simulation methods. Future studies should focus on coupling effects between urbanization in urban agglomerations and the eco-environment, spatial scale coupling effects, multi-dimensional coupling effects, telecoupling effects, "one-to-many" and "many-to-many" element coupling effects, and positive and negative feedback coupling effects. There is also a need to strengthen the development and application of dynamic models for multi-element,-scale,-scenario,-module and-agent integrated spatiotemporal coupling systems and further improve theoretical innovations in coupling effect research and integrate and form complete and diverse coupling theoretical systems.