Objective To study the effect of using improved 2D computer-assisted fluoroscopic navigation through simulating 3D vertebrae image to guide pedicle screw internal fixation.Methods Posterior pedicle screw internal fixa...Objective To study the effect of using improved 2D computer-assisted fluoroscopic navigation through simulating 3D vertebrae image to guide pedicle screw internal fixation.Methods Posterior pedicle screw internal fixation,distraction展开更多
The International Skin Imaging Collaboration(ISIC)datasets are pivotal resources for researchers in machine learning for medical image analysis,especially in skin cancer detection.These datasets contain tens of thousa...The International Skin Imaging Collaboration(ISIC)datasets are pivotal resources for researchers in machine learning for medical image analysis,especially in skin cancer detection.These datasets contain tens of thousands of dermoscopic photographs,each accompanied by gold-standard lesion diagnosis metadata.Annual challenges associated with ISIC datasets have spurred significant advancements,with research papers reporting metrics surpassing those of human experts.Skin cancers are categorized into melanoma and non-melanoma types,with melanoma posing a greater threat due to its rapid potential for metastasis if left untreated.This paper aims to address challenges in skin cancer detection via visual inspection and manual examination of skin lesion images,processes historically known for their laboriousness.Despite notable advancements in machine learning and deep learning models,persistent challenges remain,largely due to the intricate nature of skin lesion images.We review research on convolutional neural networks(CNNs)in skin cancer classification and segmentation,identifying issues like data duplication and augmentation problems.We explore the efficacy of Vision Transformers(ViTs)in overcoming these challenges within ISIC dataset processing.ViTs leverage their capabilities to capture both global and local relationships within images,reducing data duplication and enhancing model generalization.Additionally,ViTs alleviate augmentation issues by effectively leveraging original data.Through a thorough examination of ViT-based methodologies,we illustrate their pivotal role in enhancing ISIC image classification and segmentation.This study offers valuable insights for researchers and practitioners looking to utilize ViTs for improved analysis of dermatological images.Furthermore,this paper emphasizes the crucial role of mathematical and computational modeling processes in advancing skin cancer detection methodologies,highlighting their significance in improving algorithmic performance and interpretability.展开更多
Early on the morning of August 15, 2006, which was the 61st anniversary of Japan’s surrender in the Second World War, Junichiro Koizumi dressed himself up in a formal tuxedo jacket with coattails and paid his sixth a...Early on the morning of August 15, 2006, which was the 61st anniversary of Japan’s surrender in the Second World War, Junichiro Koizumi dressed himself up in a formal tuxedo jacket with coattails and paid his sixth and also the last visit to the Yasukuni Shrine in his official capacity as Japan’s prime minister. Koizumi’s deliberate action taken amidst the strong protests from people both in and outside Japan has展开更多
Dragons and dragon slayers belong to a system ofsemiology.They are images with messages.Differentcultures in the world have assigned to these imageshistorical limits,conditions of use,and introducedmultiple meanings i...Dragons and dragon slayers belong to a system ofsemiology.They are images with messages.Differentcultures in the world have assigned to these imageshistorical limits,conditions of use,and introducedmultiple meanings into them.Dragons do not exist,therefore dragon slayers do not either.However,they have become an artificial existence in most cul-tures,and this existence have passed from a closed,silent existence to an oral state,open to appropria-tion by society,for there is no regulation,either nat-ural or not,which forbids imagination.Few symbols saturate human civilization sobroadly and thoroughly as those of the dragon:proudly flicking its tail across the tapestries展开更多
Time: Sept.4-6, 2008Venue: Shenzhen Convention & Exhibition CenterSponsor: Printing and Printing Equipment Industries Association of China (PEIAC)Organizers: The Exhibition Department of
Wistar rats were inoculated with purified YWK-I antibody. The anti-idiotypie antibodies were isolated from rat sera by successive passage over affinity chromatography columns of YWK-I mAb and normal mouse Igs. Specifi...Wistar rats were inoculated with purified YWK-I antibody. The anti-idiotypie antibodies were isolated from rat sera by successive passage over affinity chromatography columns of YWK-I mAb and normal mouse Igs. Specificity of anti-Id antibody was established by ELISA. The 84 kD protein inhibited the binding of anti-Id to YWK-I mAb, but failed to repress antibody against normal mouse Ig binding to YWK-I mAb. In competitive inhibition assay, 84 kD protein had shown the ability to compete with anti-Id binding to YWK-I mAb in a dose-dependent manner. Crude sperm extract showed a lower competitive ability. No effeet was found with the irrelevant 36 kD sperm protein. The antisera from the Ba1b/e mice immunized with AId contained Ab3 that reacted with 84 kD sperm protein. The binding of anti-Id to YWK-I mAb was inhibited by Ab3 in a dose-dependent fashion and Ab3 was shown to be able to induce human sparm agglutination. These results indicate that anti-Id which may mimio an epitope of the 84 kD protein could be exploited as an antigen to raise antibodies against sperm protein.展开更多
BACKGROUND In recent years,two new narrow-band imaging(NBI)classifications have been proposed:The NBI international colorectal endoscopic(NICE)classification and Japanese NBI expert team(JNET)classification.Most valid...BACKGROUND In recent years,two new narrow-band imaging(NBI)classifications have been proposed:The NBI international colorectal endoscopic(NICE)classification and Japanese NBI expert team(JNET)classification.Most validation studies of the two new NBI classifications were conducted in classification setting units by experienced endoscopists,and the application of use in different centers among endoscopists with different endoscopy skills remains unknown.AIM To evaluate clinical application and possible problems of NICE and JNET classification for the differential diagnosis of colorectal cancer and precancerous lesions.METHODS Six endoscopists with varying levels of experience participated in this study.Eighty-seven consecutive patients with a total of 125 lesions were photographed during non-magnifying conventional white-light colonoscopy,non-magnifying NBI,and magnifying NBI.The three groups of endoscopic pictures of each lesion were evaluated by the six endoscopists in randomized order using the NICE and JENT classifications separately.Then we calculated the six endoscopists’sensitivity,specificity,accuracy,positive predictive value,and negative predictive value for each category of the two classifications.RESULTS The sensitivity,specificity,and accuracy of JNET classification type 1 and 3 were similar to NICE classification type 1 and 3 in both the highly experienced endoscopist(HEE)and less-experienced endoscopist(LEE)groups.The specificity of JNET classification type 1 and 3 and NICE classification type 3 in both the HEE and LEE groups was>95%,and the overall interobserver agreement was good in both groups.The sensitivity of NICE classification type 3 lesions for diagnosis of SM-d carcinoma in the HEE group was significantly superior to that in the LEE group(91.7%vs 83.3%;P=0.042).The sensitivity of JNET classification type 2B lesions for the diagnosis of high-grade dysplasia or superficial submucosal invasive carcinoma in the HEE and LEE groups was 53.8%and 51.3%,respectively.Compared with other types of JNET classification,the diagnostic ability of type 2B was the weakest.CONCLUSION The treatment strategy of the two classification type 1 and 3 lesions can be based on the results of endoscopic examination.JNET type 2B lesions need further examination.展开更多
The Annual International Imaging Genetics Conferences focus on the advancement of the new discipline, Imaging Genetics, and the transdisciplinary fusion that is its foundation. The Conferences bring together national ...The Annual International Imaging Genetics Conferences focus on the advancement of the new discipline, Imaging Genetics, and the transdisciplinary fusion that is its foundation. The Conferences bring together national and international experts in neuroimaging, genetics, data-mining, visualization and statistics, to present their research and findings as they relate to the field of Imaging Genetics.展开更多
Adhesion molecule CD146 (100-130kDa) belongs to the immunoglobulin super family and it is originally identified as a biomarker for melanoma. Recently, CD146 is found as
After years of development,biosensors based on imaging ellipsometry and biosensors based on total internal reflection imaging ellipsometry have been successfully implemented in various engineering systems.Their experi...After years of development,biosensors based on imaging ellipsometry and biosensors based on total internal reflection imaging ellipsometry have been successfully implemented in various engineering systems.Their experimental setups,detection principles,and biological and clinical applications are briefly reviewed.展开更多
In the 1930s and 1940s,foreign writers gathered in Yan’an drew the curtain back on recognition of China’s international image through their writings on the“red Mecca.”The international perspective on the image of ...In the 1930s and 1940s,foreign writers gathered in Yan’an drew the curtain back on recognition of China’s international image through their writings on the“red Mecca.”The international perspective on the image of Yan’an was shaped by the combined efforts of Yan’an writings by foreign writers and journalists in the interlocking cultural context of history and society.With revolutionary individual consciousness and high artistic creativity,the Yan’an narration of foreign writers had striking shared characteristics:a real sense of presence and a realistic significance beyond their times.Their discovery of the revolutionary power generated by the Chinese people and their calling for and shaping of“heroes of the masses”and their pursuit of“the character of the people”represented the spiritual dimension of their Yan’an writings,a dimension that was distinct from that of local writers.The foreign writers’creative practice and the creative experience of local writers refracted off each other,juxtaposing mirror images of Yan’an at home and abroad and promoting the modernity and cosmopolitanism of Yan’an literature in the intertextuality between reality and literature.Together with local writers,writers from abroad participated in the creation of Chinese revolutionary history and culture,bringing their personal discourse into the discourse of China’s new era and completing the restatement of their cultural identity.The global identity of Yan’an went through a difficult process of historical self-creation,breaking through the limitations of its international image and realizing the self-proving nature of modern Chinese history.展开更多
文摘Objective To study the effect of using improved 2D computer-assisted fluoroscopic navigation through simulating 3D vertebrae image to guide pedicle screw internal fixation.Methods Posterior pedicle screw internal fixation,distraction
文摘The International Skin Imaging Collaboration(ISIC)datasets are pivotal resources for researchers in machine learning for medical image analysis,especially in skin cancer detection.These datasets contain tens of thousands of dermoscopic photographs,each accompanied by gold-standard lesion diagnosis metadata.Annual challenges associated with ISIC datasets have spurred significant advancements,with research papers reporting metrics surpassing those of human experts.Skin cancers are categorized into melanoma and non-melanoma types,with melanoma posing a greater threat due to its rapid potential for metastasis if left untreated.This paper aims to address challenges in skin cancer detection via visual inspection and manual examination of skin lesion images,processes historically known for their laboriousness.Despite notable advancements in machine learning and deep learning models,persistent challenges remain,largely due to the intricate nature of skin lesion images.We review research on convolutional neural networks(CNNs)in skin cancer classification and segmentation,identifying issues like data duplication and augmentation problems.We explore the efficacy of Vision Transformers(ViTs)in overcoming these challenges within ISIC dataset processing.ViTs leverage their capabilities to capture both global and local relationships within images,reducing data duplication and enhancing model generalization.Additionally,ViTs alleviate augmentation issues by effectively leveraging original data.Through a thorough examination of ViT-based methodologies,we illustrate their pivotal role in enhancing ISIC image classification and segmentation.This study offers valuable insights for researchers and practitioners looking to utilize ViTs for improved analysis of dermatological images.Furthermore,this paper emphasizes the crucial role of mathematical and computational modeling processes in advancing skin cancer detection methodologies,highlighting their significance in improving algorithmic performance and interpretability.
文摘Early on the morning of August 15, 2006, which was the 61st anniversary of Japan’s surrender in the Second World War, Junichiro Koizumi dressed himself up in a formal tuxedo jacket with coattails and paid his sixth and also the last visit to the Yasukuni Shrine in his official capacity as Japan’s prime minister. Koizumi’s deliberate action taken amidst the strong protests from people both in and outside Japan has
文摘Dragons and dragon slayers belong to a system ofsemiology.They are images with messages.Differentcultures in the world have assigned to these imageshistorical limits,conditions of use,and introducedmultiple meanings into them.Dragons do not exist,therefore dragon slayers do not either.However,they have become an artificial existence in most cul-tures,and this existence have passed from a closed,silent existence to an oral state,open to appropria-tion by society,for there is no regulation,either nat-ural or not,which forbids imagination.Few symbols saturate human civilization sobroadly and thoroughly as those of the dragon:proudly flicking its tail across the tapestries
文摘Time: Sept.4-6, 2008Venue: Shenzhen Convention & Exhibition CenterSponsor: Printing and Printing Equipment Industries Association of China (PEIAC)Organizers: The Exhibition Department of
文摘Wistar rats were inoculated with purified YWK-I antibody. The anti-idiotypie antibodies were isolated from rat sera by successive passage over affinity chromatography columns of YWK-I mAb and normal mouse Igs. Specificity of anti-Id antibody was established by ELISA. The 84 kD protein inhibited the binding of anti-Id to YWK-I mAb, but failed to repress antibody against normal mouse Ig binding to YWK-I mAb. In competitive inhibition assay, 84 kD protein had shown the ability to compete with anti-Id binding to YWK-I mAb in a dose-dependent manner. Crude sperm extract showed a lower competitive ability. No effeet was found with the irrelevant 36 kD sperm protein. The antisera from the Ba1b/e mice immunized with AId contained Ab3 that reacted with 84 kD sperm protein. The binding of anti-Id to YWK-I mAb was inhibited by Ab3 in a dose-dependent fashion and Ab3 was shown to be able to induce human sparm agglutination. These results indicate that anti-Id which may mimio an epitope of the 84 kD protein could be exploited as an antigen to raise antibodies against sperm protein.
基金Supported by Digestive Medical Coordinated Development Center of Beijing Hospitals Authority,No.XXZ015Capital Citizens Health Cultivation Project of Beijing Municipal Science&Technology Commission,No.Z161100000116084+1 种基金Medical and Health Public Foundation of Beijing,No.YWJKJJHKYJJ-B17262-067Science and Technology Development Project of China State Railway Group,No.N2019Z004.
文摘BACKGROUND In recent years,two new narrow-band imaging(NBI)classifications have been proposed:The NBI international colorectal endoscopic(NICE)classification and Japanese NBI expert team(JNET)classification.Most validation studies of the two new NBI classifications were conducted in classification setting units by experienced endoscopists,and the application of use in different centers among endoscopists with different endoscopy skills remains unknown.AIM To evaluate clinical application and possible problems of NICE and JNET classification for the differential diagnosis of colorectal cancer and precancerous lesions.METHODS Six endoscopists with varying levels of experience participated in this study.Eighty-seven consecutive patients with a total of 125 lesions were photographed during non-magnifying conventional white-light colonoscopy,non-magnifying NBI,and magnifying NBI.The three groups of endoscopic pictures of each lesion were evaluated by the six endoscopists in randomized order using the NICE and JENT classifications separately.Then we calculated the six endoscopists’sensitivity,specificity,accuracy,positive predictive value,and negative predictive value for each category of the two classifications.RESULTS The sensitivity,specificity,and accuracy of JNET classification type 1 and 3 were similar to NICE classification type 1 and 3 in both the highly experienced endoscopist(HEE)and less-experienced endoscopist(LEE)groups.The specificity of JNET classification type 1 and 3 and NICE classification type 3 in both the HEE and LEE groups was>95%,and the overall interobserver agreement was good in both groups.The sensitivity of NICE classification type 3 lesions for diagnosis of SM-d carcinoma in the HEE group was significantly superior to that in the LEE group(91.7%vs 83.3%;P=0.042).The sensitivity of JNET classification type 2B lesions for the diagnosis of high-grade dysplasia or superficial submucosal invasive carcinoma in the HEE and LEE groups was 53.8%and 51.3%,respectively.Compared with other types of JNET classification,the diagnostic ability of type 2B was the weakest.CONCLUSION The treatment strategy of the two classification type 1 and 3 lesions can be based on the results of endoscopic examination.JNET type 2B lesions need further examination.
文摘The Annual International Imaging Genetics Conferences focus on the advancement of the new discipline, Imaging Genetics, and the transdisciplinary fusion that is its foundation. The Conferences bring together national and international experts in neuroimaging, genetics, data-mining, visualization and statistics, to present their research and findings as they relate to the field of Imaging Genetics.
文摘Adhesion molecule CD146 (100-130kDa) belongs to the immunoglobulin super family and it is originally identified as a biomarker for melanoma. Recently, CD146 is found as
基金The National Basic Research Program of China(Grant No.2009CB320300)the National High Technology Research Development Program(863 Program)of China(Grant Nos.2008AA02Z419 and NNSFC 20805053)are acknowledged for their financial supports.
文摘After years of development,biosensors based on imaging ellipsometry and biosensors based on total internal reflection imaging ellipsometry have been successfully implemented in various engineering systems.Their experimental setups,detection principles,and biological and clinical applications are briefly reviewed.
基金This paper is a phased achievement sponsored on a rolling basis by the key project“Yan’an Literature and Art and the Study of Chinese Literature in the 20th Century,”(Grants No.11&ZD113)of the National Social Science Fund of China.
文摘In the 1930s and 1940s,foreign writers gathered in Yan’an drew the curtain back on recognition of China’s international image through their writings on the“red Mecca.”The international perspective on the image of Yan’an was shaped by the combined efforts of Yan’an writings by foreign writers and journalists in the interlocking cultural context of history and society.With revolutionary individual consciousness and high artistic creativity,the Yan’an narration of foreign writers had striking shared characteristics:a real sense of presence and a realistic significance beyond their times.Their discovery of the revolutionary power generated by the Chinese people and their calling for and shaping of“heroes of the masses”and their pursuit of“the character of the people”represented the spiritual dimension of their Yan’an writings,a dimension that was distinct from that of local writers.The foreign writers’creative practice and the creative experience of local writers refracted off each other,juxtaposing mirror images of Yan’an at home and abroad and promoting the modernity and cosmopolitanism of Yan’an literature in the intertextuality between reality and literature.Together with local writers,writers from abroad participated in the creation of Chinese revolutionary history and culture,bringing their personal discourse into the discourse of China’s new era and completing the restatement of their cultural identity.The global identity of Yan’an went through a difficult process of historical self-creation,breaking through the limitations of its international image and realizing the self-proving nature of modern Chinese history.