连接节点的设计是保证木-混凝土混合结构中两种材料协同工作的基础.为研究常用工程木-混凝土螺栓连接节点的力学性能及破坏模式,分别选用正交胶合木(Crosslaminated timber,CLT)-混凝土螺栓连接和云杉-松木-冷杉(Spruce Pine Fir,SPF)...连接节点的设计是保证木-混凝土混合结构中两种材料协同工作的基础.为研究常用工程木-混凝土螺栓连接节点的力学性能及破坏模式,分别选用正交胶合木(Crosslaminated timber,CLT)-混凝土螺栓连接和云杉-松木-冷杉(Spruce Pine Fir,SPF)规格材-混凝土螺栓连接作为试验对象,设计了27组单调加载试验和低周往复加载试验,归纳并对比了两类木-混凝土螺栓连接的典型破坏模式.结果表明:木-混凝土螺栓连接节点承载力大小与螺栓屈服模式相关,CLT-混凝土螺栓连接相较于SPF-混凝土螺栓连接更易发生双铰破坏,且CLT-混凝土螺栓连接具有更好的延性.基于对两类连接力学性能差异的影响机理分析,考虑钢垫板对承载力的影响,并引入CLT等效截面,提出了木-混凝土螺栓连接的承载力力学模型.计算结果与试验结果对比的平均误差为12.18%,表明计算值与试验值吻合良好,可为木-混凝土螺栓连接的设计与应用提供参考.展开更多
The changes and correlations of muscle pH, glycogen, lactic acid and in- tramuscular fat oxidation in Duroc pigs 10 d after their slaughter, and the effects of different storage temperature and time on Duroc muscle pH...The changes and correlations of muscle pH, glycogen, lactic acid and in- tramuscular fat oxidation in Duroc pigs 10 d after their slaughter, and the effects of different storage temperature and time on Duroc muscle pH value, water loss rate, glycogen, lactic acid and 2-thiobarbituric acid (TBA) were studied. The results showed that during the 10 h after the slaughter, the pH value was decreased rapid- ly, the lactic acid content was increased significantly, while the glycogen and TBA contents were remained stable. At the storage temperature of 4 ℃, storage time showed no significant effects on Duroc muscle pH value and glycogen, lactic acid and TBA contents. At the storage temperature of -20 ℃, storage temperature had significant effects on pH value, while no significant effects on other indicators. The correlation analysis demonstrated that during the 10 h after the slaughter, the TBA content was negatively related to glycogen content (P〈0.05), but positively related to lactic content (P〈0.05); the pH value was negatively related to lactic acid content (P〈0.05). At the storage temperature of 4 ℃, the TBA content was negatively relat- ed to water loss rate (P〈0.01) and lactic acid content (P〈0.05); the water loss rate was positively related to pH value (P〈0.01) and lactic acid content (P〈0.05). At the storage temperature of -20 ℃, the TBA content was negatively related to pH value (P〈0.01) and positively related to water loss rate (P〈0.05); the water loss rate was negatively related to pH value (P〈0.01) and lactic acid content (P〈0.05).展开更多
Objective: To establish a HPLC method using fluorometric detection for quantitatively determinating intracellular accumulation of verapamil (VER). Methods: Chromatography column was packed with spherisorb ODS(250&...Objective: To establish a HPLC method using fluorometric detection for quantitatively determinating intracellular accumulation of verapamil (VER). Methods: Chromatography column was packed with spherisorb ODS(250×4.6 mm,10 μm).The mobile phase consisted of the mixture of methanol:NaAC (0.01 mol/L): diethylamine (65:35:0.25). The detect wavelength was 280/310 nm (Ex/Em). Results: The standard curve showed a good correlation between concentration and peak area within the range of 5-50 ng/ml. RSD was 0.86%, and recovery radio of loading sample, 100%. The detection limit for cell sample was 0.2-148 ng/ml. Intracellular accumulation of VER was observed to decrease from a 13 fold to 5 fold in K562/ADM cells, and from a 3.5 fold to 4.3 fold in K562/VER cells and from a 2.1 fold to 6.5 fold in K562/ADM/VER cells, compared with the relevant control cells. Conclusion: HPLC method was proved to be sensitive and specific for using to quantitatively determine the intracellular accumulation of VER.展开更多
Using oxidation with KMnO4. KMnO4/acetone-H2O. NAS. followed by Polonovskyreaction and imine formation. the N-deethylation of six norditerpenoid alkaloids 6-epi-forsticille.yunnaconitine. 3. 13-diacetylyunnaconitine. ...Using oxidation with KMnO4. KMnO4/acetone-H2O. NAS. followed by Polonovskyreaction and imine formation. the N-deethylation of six norditerpenoid alkaloids 6-epi-forsticille.yunnaconitine. 3. 13-diacetylyunnaconitine. 13-dehydroxy-indaconitine. indaconitine and 3-acetylpseudaconine are reported in 36-60% yields.展开更多
Objective: To evaluate the immunoisola ti ng effects of barium-alginate microencapsulation on islets allograft survival. Methods: The nonmicroencapsulated and microencapsulated islets w ere transplanted under the kid...Objective: To evaluate the immunoisola ti ng effects of barium-alginate microencapsulation on islets allograft survival. Methods: The nonmicroencapsulated and microencapsulated islets w ere transplanted under the kidney capsule or intraperitoneally into Wistar rat w ith STZ-induced diabetes. The blood glucose and insulin secretion of grafts wer e observed. Graft function was tested by oral glucose tolerance test (OGTT). Results: ①Five diabetic rats became normoglycemic for 48 to 72 h after microencapsulated islets transplantation. The survival of transplanted i slets was on an average of 6 W. ②The normalization of the glycemia and insulin in the transplanted rats was associated with normal glucose and insulin profiles in response to OGTT. Conclusion: Microencapsulation with barium -alginate membrane can prolong islet survival and protect islets against allore jection.展开更多
Structure analyses for hydrate models of ethyleneimine oligomer (5-mer as model of PEI) were investigated by quantum chemical calculations. Conformation energies and structures optimized for hydrate models of (ttt)5 a...Structure analyses for hydrate models of ethyleneimine oligomer (5-mer as model of PEI) were investigated by quantum chemical calculations. Conformation energies and structures optimized for hydrate models of (ttt)5 and (tgt)5 conformers were examined. Hydrate ratio, h [h = H2O/N (mol)], was set from 0.5 to 2. In anhydrates, (tg+t)5 conformer was more stable (?1.8 kcal/m.u.) than (ttt)5. In hydrates, (ttt)5 conformers were more stable (?0.7 - ?4.3) than (tg+t)5. These results corresponded to experimental results that anhydrous linear PEI crystal changes from double helical to single planar chain in hydration process. Structures calculated for (ttt)5 agreed in those observed for hydrates of PEI. In all (tg+t)5 conformers, O???H bonds between waters were found with the decreases of N???H bonds between imino group and water. The O???H bonds in (tg+t)5 conformer resulted in its high chain torsion, and strongly related with instability and structure change (large swelling).展开更多
In rough communication, because each agent has a different language and can not provide precise communication to each other, the concept translated among multi-agents will loss some information, and this results in a ...In rough communication, because each agent has a different language and can not provide precise communication to each other, the concept translated among multi-agents will loss some information, and this results in a less or rougher concept. With different translation sequences the amount of the missed knowledge is varied. The λ-optimal translation sequence of rough communication, which concerns both every agent and the last agent taking part in rough communication to get information as much as he (or she) can, is given. In order to get the λ-optimal translation sequence, a genetic algorithm is used. Analysis and simulation of the algorithm demonstrate the effectiveness of the approach.展开更多
Abstract Vacuum insulation of -1 MV is a common issue for the HV bushing and the accel- erator for the ITER neutral beam injector (NBI). The HV bushing as an insulating feedthrough has a five-stage structure and eac...Abstract Vacuum insulation of -1 MV is a common issue for the HV bushing and the accel- erator for the ITER neutral beam injector (NBI). The HV bushing as an insulating feedthrough has a five-stage structure and each stage consists of double-layered insulators. To sustain -1 MV in vacuum, reduction of electric field at several triple points existing around the double-layered insulators is a critical issue. To reduce electric field simultaneously at these points, three types of stress ring have been developed. In a voltage holding test of a full-scale mockup equipped with these stress rings, 120% of rated voltage was sustained and the voltage holding capability required in ITER was verified. In the MeV accelerator, whose target is the acceleration of a H- ion beam of 1 MeV, 200 A/mS, the gap between the grid support was extended to suppress breakdowns triggered by electric field concentration at the edge and corner of the grid support. This modi- fication improved the voltage holding capability in vacuum, and the MeV accelerator succeeded in sustaining -1 MV stably, b-~rthermore, it appeared that the H- ions beam was deflected and a part of the beam was intercepted at the acceleration grid, This causes high heat load on the grids and breakdowns during beam acceleration. To suppress the direct interception, a new grid was designed with proper aperture displacement based on a three dimensional beam trajectory analysis, As a result, 980 keV, 185 A/ms H- ion beam acceleration has been demonstrated, which is close to the ITER requirement.展开更多
The structural characteristics of different alkoxides of Y. Ba and Cu are studied with quantum chemi-cal CNDO /2 calculations. The relative hydrolysis rate coefficients k_M of them are obtained according tothe relati...The structural characteristics of different alkoxides of Y. Ba and Cu are studied with quantum chemi-cal CNDO /2 calculations. The relative hydrolysis rate coefficients k_M of them are obtained according tothe relationship between frontier orbitals and organic chemical reactions. Based on the above results. properexperimental conditions for the preparation of homogeneous ultra-purity. submicro high-T_cYBa_2Cu_3O_(7-δ) superconducting powders are proposed.展开更多
An investigation into the aircraft flight simulation and control system is presented in this paper. The study was firstly focused on the establishment of an integrated hardware-in-the-loop(HITL) platform for aircraf...An investigation into the aircraft flight simulation and control system is presented in this paper. The study was firstly focused on the establishment of an integrated hardware-in-the-loop(HITL) platform for aircraft flight simulation based on MATLAB/Simulink + dSPACE. The platform combines the abundant software and hardware resources of dSPACE simulation platform to simulate the flight attitude of an aircraft in six-DOF ( degree of freedom) motion. Based on the platform, the study was then focused on the flight numerical simulation by taking a loitering aerial vehicle as an example. An aircraft mathematical model was created for a modular design and off-line numerical simulation based on MATLAB/Simulink. Finally, the study was focused on the control system design of the loitering aerial vehicle and conduct of an HITL simulation experiment for the vehicle pitch control. The experiment verifies the system design and control effectiveness. Research results show that the dSPACE simulation system provides a real time good experimental platform to improve the efficiency of study and development of a flight control system.展开更多
文摘连接节点的设计是保证木-混凝土混合结构中两种材料协同工作的基础.为研究常用工程木-混凝土螺栓连接节点的力学性能及破坏模式,分别选用正交胶合木(Crosslaminated timber,CLT)-混凝土螺栓连接和云杉-松木-冷杉(Spruce Pine Fir,SPF)规格材-混凝土螺栓连接作为试验对象,设计了27组单调加载试验和低周往复加载试验,归纳并对比了两类木-混凝土螺栓连接的典型破坏模式.结果表明:木-混凝土螺栓连接节点承载力大小与螺栓屈服模式相关,CLT-混凝土螺栓连接相较于SPF-混凝土螺栓连接更易发生双铰破坏,且CLT-混凝土螺栓连接具有更好的延性.基于对两类连接力学性能差异的影响机理分析,考虑钢垫板对承载力的影响,并引入CLT等效截面,提出了木-混凝土螺栓连接的承载力力学模型.计算结果与试验结果对比的平均误差为12.18%,表明计算值与试验值吻合良好,可为木-混凝土螺栓连接的设计与应用提供参考.
基金Supported by Funds for Swine Innovation Team Construction of Shandong Provincial Modern Agriculture Industry Technology System(SDAIT-06-011-03)Fine Breeds Engineering Project of Shandong Province(2011LZ013-01)China Swine Industry Technology System(CARS-36)~~
文摘The changes and correlations of muscle pH, glycogen, lactic acid and in- tramuscular fat oxidation in Duroc pigs 10 d after their slaughter, and the effects of different storage temperature and time on Duroc muscle pH value, water loss rate, glycogen, lactic acid and 2-thiobarbituric acid (TBA) were studied. The results showed that during the 10 h after the slaughter, the pH value was decreased rapid- ly, the lactic acid content was increased significantly, while the glycogen and TBA contents were remained stable. At the storage temperature of 4 ℃, storage time showed no significant effects on Duroc muscle pH value and glycogen, lactic acid and TBA contents. At the storage temperature of -20 ℃, storage temperature had significant effects on pH value, while no significant effects on other indicators. The correlation analysis demonstrated that during the 10 h after the slaughter, the TBA content was negatively related to glycogen content (P〈0.05), but positively related to lactic content (P〈0.05); the pH value was negatively related to lactic acid content (P〈0.05). At the storage temperature of 4 ℃, the TBA content was negatively relat- ed to water loss rate (P〈0.01) and lactic acid content (P〈0.05); the water loss rate was positively related to pH value (P〈0.01) and lactic acid content (P〈0.05). At the storage temperature of -20 ℃, the TBA content was negatively related to pH value (P〈0.01) and positively related to water loss rate (P〈0.05); the water loss rate was negatively related to pH value (P〈0.01) and lactic acid content (P〈0.05).
文摘Objective: To establish a HPLC method using fluorometric detection for quantitatively determinating intracellular accumulation of verapamil (VER). Methods: Chromatography column was packed with spherisorb ODS(250×4.6 mm,10 μm).The mobile phase consisted of the mixture of methanol:NaAC (0.01 mol/L): diethylamine (65:35:0.25). The detect wavelength was 280/310 nm (Ex/Em). Results: The standard curve showed a good correlation between concentration and peak area within the range of 5-50 ng/ml. RSD was 0.86%, and recovery radio of loading sample, 100%. The detection limit for cell sample was 0.2-148 ng/ml. Intracellular accumulation of VER was observed to decrease from a 13 fold to 5 fold in K562/ADM cells, and from a 3.5 fold to 4.3 fold in K562/VER cells and from a 2.1 fold to 6.5 fold in K562/ADM/VER cells, compared with the relevant control cells. Conclusion: HPLC method was proved to be sensitive and specific for using to quantitatively determine the intracellular accumulation of VER.
文摘Using oxidation with KMnO4. KMnO4/acetone-H2O. NAS. followed by Polonovskyreaction and imine formation. the N-deethylation of six norditerpenoid alkaloids 6-epi-forsticille.yunnaconitine. 3. 13-diacetylyunnaconitine. 13-dehydroxy-indaconitine. indaconitine and 3-acetylpseudaconine are reported in 36-60% yields.
基金Subject of Jiangsu Province135 Projects (2001 31)
文摘Objective: To evaluate the immunoisola ti ng effects of barium-alginate microencapsulation on islets allograft survival. Methods: The nonmicroencapsulated and microencapsulated islets w ere transplanted under the kidney capsule or intraperitoneally into Wistar rat w ith STZ-induced diabetes. The blood glucose and insulin secretion of grafts wer e observed. Graft function was tested by oral glucose tolerance test (OGTT). Results: ①Five diabetic rats became normoglycemic for 48 to 72 h after microencapsulated islets transplantation. The survival of transplanted i slets was on an average of 6 W. ②The normalization of the glycemia and insulin in the transplanted rats was associated with normal glucose and insulin profiles in response to OGTT. Conclusion: Microencapsulation with barium -alginate membrane can prolong islet survival and protect islets against allore jection.
文摘Structure analyses for hydrate models of ethyleneimine oligomer (5-mer as model of PEI) were investigated by quantum chemical calculations. Conformation energies and structures optimized for hydrate models of (ttt)5 and (tgt)5 conformers were examined. Hydrate ratio, h [h = H2O/N (mol)], was set from 0.5 to 2. In anhydrates, (tg+t)5 conformer was more stable (?1.8 kcal/m.u.) than (ttt)5. In hydrates, (ttt)5 conformers were more stable (?0.7 - ?4.3) than (tg+t)5. These results corresponded to experimental results that anhydrous linear PEI crystal changes from double helical to single planar chain in hydration process. Structures calculated for (ttt)5 agreed in those observed for hydrates of PEI. In all (tg+t)5 conformers, O???H bonds between waters were found with the decreases of N???H bonds between imino group and water. The O???H bonds in (tg+t)5 conformer resulted in its high chain torsion, and strongly related with instability and structure change (large swelling).
基金supported by the National Natural Science Foundation of China(61070241)the Natural Science Foundation of Shandong Province(ZR2010FM035)+1 种基金the Science and Technology Foundation of University of Jinan(XKY1031XKY0808)
文摘In rough communication, because each agent has a different language and can not provide precise communication to each other, the concept translated among multi-agents will loss some information, and this results in a less or rougher concept. With different translation sequences the amount of the missed knowledge is varied. The λ-optimal translation sequence of rough communication, which concerns both every agent and the last agent taking part in rough communication to get information as much as he (or she) can, is given. In order to get the λ-optimal translation sequence, a genetic algorithm is used. Analysis and simulation of the algorithm demonstrate the effectiveness of the approach.
文摘Abstract Vacuum insulation of -1 MV is a common issue for the HV bushing and the accel- erator for the ITER neutral beam injector (NBI). The HV bushing as an insulating feedthrough has a five-stage structure and each stage consists of double-layered insulators. To sustain -1 MV in vacuum, reduction of electric field at several triple points existing around the double-layered insulators is a critical issue. To reduce electric field simultaneously at these points, three types of stress ring have been developed. In a voltage holding test of a full-scale mockup equipped with these stress rings, 120% of rated voltage was sustained and the voltage holding capability required in ITER was verified. In the MeV accelerator, whose target is the acceleration of a H- ion beam of 1 MeV, 200 A/mS, the gap between the grid support was extended to suppress breakdowns triggered by electric field concentration at the edge and corner of the grid support. This modi- fication improved the voltage holding capability in vacuum, and the MeV accelerator succeeded in sustaining -1 MV stably, b-~rthermore, it appeared that the H- ions beam was deflected and a part of the beam was intercepted at the acceleration grid, This causes high heat load on the grids and breakdowns during beam acceleration. To suppress the direct interception, a new grid was designed with proper aperture displacement based on a three dimensional beam trajectory analysis, As a result, 980 keV, 185 A/ms H- ion beam acceleration has been demonstrated, which is close to the ITER requirement.
文摘The structural characteristics of different alkoxides of Y. Ba and Cu are studied with quantum chemi-cal CNDO /2 calculations. The relative hydrolysis rate coefficients k_M of them are obtained according tothe relationship between frontier orbitals and organic chemical reactions. Based on the above results. properexperimental conditions for the preparation of homogeneous ultra-purity. submicro high-T_cYBa_2Cu_3O_(7-δ) superconducting powders are proposed.
基金Sponsored by the Ministerial Level Advanced Research Foundation(A26020060253)
文摘An investigation into the aircraft flight simulation and control system is presented in this paper. The study was firstly focused on the establishment of an integrated hardware-in-the-loop(HITL) platform for aircraft flight simulation based on MATLAB/Simulink + dSPACE. The platform combines the abundant software and hardware resources of dSPACE simulation platform to simulate the flight attitude of an aircraft in six-DOF ( degree of freedom) motion. Based on the platform, the study was then focused on the flight numerical simulation by taking a loitering aerial vehicle as an example. An aircraft mathematical model was created for a modular design and off-line numerical simulation based on MATLAB/Simulink. Finally, the study was focused on the control system design of the loitering aerial vehicle and conduct of an HITL simulation experiment for the vehicle pitch control. The experiment verifies the system design and control effectiveness. Research results show that the dSPACE simulation system provides a real time good experimental platform to improve the efficiency of study and development of a flight control system.