The establishment of a dependable electrophysiological detection platform is paramount for cardiology and neuroscience research.In the past decade,devices based on micro and nanoscale sensing and control technologies ...The establishment of a dependable electrophysiological detection platform is paramount for cardiology and neuroscience research.In the past decade,devices based on micro and nanoscale sensing and control technologies have been developed to construct electrophysiological platforms.Their unique morphological advantages and novel processing methods offer the potential for high-throughput,high-fidelity electrical signal recording.In this review,we analyze the structure,transmembrane strategies,and electrophysiological detection methods of active/passive micro and nano sensing platforms.We also provide an outlook on their vast potential for development in light of the opportunities and challenges facing micro and nano sensing technology,with the aim of pushing for higher-level electrophysiological platform construction to meet the needs of experimental research and clinical applications.展开更多
基金the National Natural Science Foundation of China(Nos.62171483 and 82061148011)the Zhejiang Provincial Natural Science Foundation of China(No.LZ23F010004)+1 种基金the“Pioneer”and“Leading Goose”R&D Program of Zhejiang Province(No.2023C03029)the Traditional Chinese Medicine Project of Zhejiang Province(No.2021ZA084),China.
文摘The establishment of a dependable electrophysiological detection platform is paramount for cardiology and neuroscience research.In the past decade,devices based on micro and nanoscale sensing and control technologies have been developed to construct electrophysiological platforms.Their unique morphological advantages and novel processing methods offer the potential for high-throughput,high-fidelity electrical signal recording.In this review,we analyze the structure,transmembrane strategies,and electrophysiological detection methods of active/passive micro and nano sensing platforms.We also provide an outlook on their vast potential for development in light of the opportunities and challenges facing micro and nano sensing technology,with the aim of pushing for higher-level electrophysiological platform construction to meet the needs of experimental research and clinical applications.
