Risk factors associated with intraoperative persistent hypotension in pancreaticoduodenectomy

BACKGROUND Intraoperative persistent hypotension(IPH)during pancreaticoduodenectomy(PD)is linked to adverse postoperative outcomes,yet its risk factors remain unclear.AIM To clarify the risk factors associated with IPH during PD,ensuring patient safety in the perioperative period.METHODS A retrospective analysis of patient records from January 2018 to December 2022 at the First Affiliated Hospital of Nanjing Medical University identified factors associated with IPH in PD.These factors included age,gender,body mass index,American Society of Anesthesiologists classification,comorbidities,medication history,operation duration,fluid balance,blood loss,urine output,and blood gas parameters.IPH was defined as sustained mean arterial pressure<65 mmHg,requiring prolonged deoxyepinephrine infusion for>30 min despite additional deoxyepinephrine and fluid treatments.RESULTS Among 1596 PD patients,661(41.42%)experienced IPH.Multivariate logistic regression identified key risk factors:increased age[odds ratio(OR):1.20 per decade,95%confidence interval(CI):1.08-1.33](P<0.001),longer surgery duration(OR:1.15 per additional hour,95%CI:1.05-1.26)(P<0.01),and greater blood loss(OR:1.18 per 250-mL increment,95%CI:1.06-1.32)(P<0.01).A novel finding was the association of arterial blood Ca^(2+)<1.05 mmol/L with IPH(OR:2.03,95%CI:1.65-2.50)(P<0.001).CONCLUSION IPH during PD is independently associated with older age,prolonged surgery,increased blood loss,and lower plasma Ca^(2+).

Coseismic site response and slope instability using periodic boundary conditions in the material point method

This paper proposed the explicit generalized-a time scheme and periodic boundary conditions in the material point method(MPM)for the simulation of coseismic site response.The proposed boundary condition uses an intuitive particle-relocation algorithm ensuring material points always remain within the computational mesh.The explicit generalized-a time scheme was implemented in MPM to enable the damping of spurious high frequency oscillations.Firstly,the MPM was verified against finite element method(FEM).Secondly,ability of the MPM in capturing the analytical transfer function was investigated.Thirdly,a symmetric embankment was adopted to investigate the effects of ground motion arias intensity(I_(a)),geometry dimensions,and constitutive models.The results show that the larger the model size,the higher the crest runout and settlement for the same ground motion.When using a Mohr-Coulomb model,the crest runout increases with increasing I_(a).However,if the strain-softening law is activated,the results are less influenced by the ground motion.Finally,the MPM results were compared with the Newmark sliding block solution.The simplified analysis herein highlights the capabilities of MPM to capture the full deformation process for earthquake engineering applications,the importance of geometry characterization,and the selection of appropriate constitutive models when simulating coseismic site response and subsequent large deformations.

A two-scale method for identifying mechanical parameters of composite materials with periodic configuration

In this paper, a two-scale method （TSM） is presented for identifying the mechanics parameters such as stiffness and strength of composite materials with small periodic configuration. Firstly, a formulation is briefly given for two-scale analysis （TSA） of the composite materials. And then a two-scale computation formulation of strains and stresses is developed by displacement solution with orthotropic material coefficients for three kinds of such composites structures, i.e., the tension column with a square cross section, the bending cantilever with a rectangular cross section and the torsion column with a circle cross section. The strength formulas for the three kinds of structures are derived and the TSM procedure is discussed. Finally the numerical results of stiffness and strength are presented and compared with experimental data. It shows that the TSM method in this paper is feasible and valid for predicting both the stiffness and the strength of the composite materials with periodic configuration.

Novel implementation of homogenization method to predict effective properties of periodic materials

Representative volume element （RVE） method and asymptotic homogenization （AH） method are two widely used methods in predicting effective properties of pe- riodic materials. This paper develops a novel implementa- tion of the AH method, which has rigorous mathematical foundation of the AH method, and also simplicity as the RVE method. This implementation can be easily realized using commercial software as a black box, and can use all kinds of elements available in commercial software to model unit cells with rather complicated microstructures, so the model may remain a fairly small scale. Several examples were car- fled out to demonstrate the simplicity and effectiveness of the new implementation.

Re-study on Recurrence Period of Stokes Wave Train with High Order Spectral Method

Owing to the Benjamin-Feir instability, the Stokes wave train experiences a modulation-demodulation process, and presents a recurrence characteristics. Stiassnie and Shemer researched the unstable evolution process and provided a theoretical formulation for the recurrence period in 1985 on the basis of the nonlinear cubic Schrodinger equation （NLS）. However, NLS has limitations on the narrow band and the weak nonlinearity. The recurrence period is re-investigated in this paper by using a highly efficient High Order Spectral （HOS） method, which can be applied for the direct phase- resolved simulation of the nonlinear wave train evolution. It is found that the Stiassnie and Shemer＇s formula should be modified in the cases with most unstable initial conditions, which is important for such topics as the generation mechanisms of freak waves. A new recurrence period formula is presented and some new evolution characteristics of the Stokes wave train are also discussed in details.

Two-scale finite element method for piezoelectric problem in periodic structure

The prediction of the mechanical and electric properties of piezoelectric fibre composites has become an active research area in recent years. By means of introducing a boundary layer problem, some new kinds of two-scale finite element methods for solutions to the electric potential and the displacement for composite material in periodic struc- ture under the coupled piezoelectricity are derived. The coupled two-scale relation of the electric potential and the displacement is set up, and some finite element approximate estimates and numerical examples which show the effectiveness of the method are presented.

Doubly Periodic Wave Solutions of Jaulent-Miodek Equations Using Variational Iteration Method Combined with Jacobian-function Method

One of the advantages of the variational iteration method is the free choice of initial guess. In this paper we use the basic idea of the Jacobian-function method to construct a generalized trial function with some unknown parameters. The Jaulent-Miodek equations are used to illustrate effectiveness and convenience of this method, some new explicit exact travelling wave solutions have been obtained, which include bell-type soliton solution, kink-type soliton solutions, solitary wave solutions, and doubly periodic wave solutions.

Extended F-Expansion Method and Periodic Wave Solutions for Klein-Gordon-SchrSdinger Equations

We present an extended F-expansion method for finding periodic wave solutions of nonlinear evolution equations in mathematical physics. By using extended F-expansion method, many periodic wave solutions expressed by various Jacobi elliptic functions for the Klein-Gordon-Schrodinger equations are obtained. In the limit cases, the solitary wave solutions and trigonometric function solutions for the equations are also obtained.

Synthesis and Optimization of Almost Periodic Antennas Using Floquet Modal Analysis and MoM-GEC Method

This paper presented a new Floquet analysis used to calculate the radiation for 1-D and 2-D coupled periodic antenna systems. In this way, an accurate evaluation of mutual coupling can be proven by using a new mutual interaction expression that was based on Fourier analysis. Then, this work indicated how Floquet analysis can be used to study a finite array with uniform amplitude and linear phase distribution in both x and y directions. To modelize the proposed structures, two formulations were given in a spectral and spatial domain, where the Moment (MoM) method combined with a generalized equivalent circuit (GEC) method was applied. Radiation pattern of coupled periodic antenna was shown by varying many parameters, such as frequencies, distance and Floquet states. The 3-D radiation beam of the coupled antenna array was analyzed and compared in several steering angles θs and coupling values dx. The simulation of this structure demonstrated that directivity decreased at higher coupling values. The secondary lobs in the antenna radiation pattern affected the main lobe gain by energy dispersal and considerable increasing of side lobe level (SLL) may be achieved. Therefore, the sweeping of the radiation beam in several steering directions affected the electromagnetic performance of the antenna system: the directivity at the steering angle θs = π&#8260;3 was more damaged and had 19.99 dB while the second at θs = 0 had about 35.11 dB. This parametric study of coupled structure used to concept smart periodic antenna with sweeping radiation beam.

Identification of independent risk factors for intraoperative gastroesophageal reflux in adult patients undergoing general anesthesia

BACKGROUND Gastroesophageal reflux(GER)affects up to 20%of the adult population and is defined as troublesome and frequent symptoms of heartburn or regurgitation.GER produces significantly harmful impacts on quality of life and precipitates poor mental well-being.However,the potential risk factors for the incidence and extent of GER in adults undergoing general anesthesia remain unclear.AIM To explore independent risk factors for the incidence and extent of GER during general anesthesia induction.METHODS A retrospective study was conducted,and 601 adult patients received general anesthesia intubation or laryngeal mask surgery between July 2016 and January 2019 in Shanghai General Hospital of Nanjing Medical University.This study recruited a total of 601 adult patients undergoing general anesthesia,and the characteristics of patients and the incidence or extent of GER were recorded.The potential risk factors for the incidence of GER were explored using multivariate logistic regression,and the risk factors for the extent of GER were evaluated using multivariate linear regression.RESULTS The current study included 601 adult patients,82 patients with GER and 519 patients without GER.Overall,we noted significant differences between GER and non-GER for pharyngitis,history of GER,other digestive tract diseases,history of asthma,and the use of sufentanil(P<0.05),while no significant differences between groups were observed for sex,age,type of surgery,operative time,body mass index,intraoperative blood loss,smoking status,alcohol intake,hypertension,diabetes mellitus,psychiatric history,history of respiratory infection,history of surgery,the use of lidocaine,palliative strategies,propofol,or rocuronium bromide,state anxiety inventory,trait anxiety inventory,and selfrating depression scale(P>0.05).The results of multivariate logistic regression indicated that female sex[odds ratio(OR):2.702;95%confidence interval(CI):1.144-6.378;P=0.023],increased age(OR:1.031;95%CI:1.008-1.056;P=0.009),pharyngitis(OR:31.388;95%CI:15.709-62.715;P<0.001),and history of GER(OR:11.925;95%CI:4.184-33.989;P<0.001)were associated with an increased risk of GER,whereas the use of propofol could protect against the risk of GER(OR:0.942;95%CI:0.892-0.994;P=0.031).Finally,age(P=0.004),operative time(P<0.001),pharyngitis(P<0.001),history of GER(P=0.024),and hypertension(P=0.017)were significantly associated with GER time.CONCLUSION This study identified the risk factors for GER in patients undergoing general anesthesia including female sex,increased age,pharyngitis,and history of GER.

Finding Periodic Solutions of Ordinary Differential Equations by the Homotopy Method

As an important aspect of applications, it is discussed how to find periodic solutions for ordinary differential equations. By using the homotopy method, a global method for finding those solutions is proposed.

Existence and Uniqueness of 2π-Periodic Solution About Duffing Equation and Its Numerical Method

A new provement of the existence and uniqueness about periodic boundary value Duffing equation is established by using global inverse function theorem. An algorithm for solving differential equation that has a large convergence domain is given. Finally, a numerical example is given.

Construction of doubly-periodic solutions to nonlinear partial differential equations using improved Jacobi elliptic function expansion method and symbolic computation

Some doubly-periodic solutions of the Zakharov-Kuznetsov equation are presented. Our approach is to introduce an auxiliary ordinary differential equation and use its Jacobi elliptic function solutions to construct doubly-periodic solutions of the Zakharov-Kuznetsov equation, which has been derived by Gottwald as a two-dimensional model for nonlinear Rossby waves. When the modulus k →1, these solutions reduce to the solitary wave solutions of the equation.

Second-order two-scale computational method for ageing linear viscoelastic problem in composite materials with periodic structure

The correspondence principle is an important mathematical technique to compute the non-ageing linear viscoelastic problem as it allows to take advantage of the computational methods originally developed for the elastic case. However, the correspon- dence principle becomes invalid when the materials exhibit ageing. To deal with this problem, a second-order two-scale （SOTS） computational method in the time domain is presented to predict the ageing linear viscoelastic performance of composite materials with a periodic structure. First, in the time domain, the SOTS formulation for calcu- lating the effective relaxation modulus and displacement approximate solutions of the ageing viscoelastic problem is formally derived. Error estimates of the displacement ap- proximate solutions for SOTS method are then given. Numerical results obtained by the SOTS method are shown and compared with those by the finite element method in a very fine mesh. Both the analytical and numerical results show that the SOTS computational method is feasible and efficient to predict the ageing linear viscoelastic performance of composite materials with a periodic structure.

An asymptotic solving method for the periodic solution of a class of disturbed nonlinear evolution equation

A class of disturbed evolution equation is considered using a simple and valid technique. We first introduce the periodic traveling-wave solution of a corresponding typical evolution equation. Then the approximate solution for an original disturbed evolution equation is obtained using the asymptotic method. We point out that the series of approximate solution is convergent and the accuracy of the asymptotic solution is studied using the fixed point theorem for the functional analysis.

ANALYSIS OF OPEN MICROSTRIP STRUCTURES BY USING DIAKOPTIC METHOD OF LINES COMBINED WITH PERIODIC BOUNDARY CONDITIONS

This paper presents the analysis of open microstrip structures by using diakoptic method of lines (ML) combined with periodic boundary conditions (PBC). The parameters of microstrip patch are obtained from patch current excited by plane wave. Impedance matrix elements are computed by using fast Fourier transform(FFT), and reduced equation is solved by using diakoptic technique. Consequently, the computing time is reduced significantly. The convergence property of simulating open structure by using PBC and the comparison of the computer time between using PBC and usual absorbing boundary condition (ABC) show the validity of the method proposed in this paper. Finally, the resonant frequency of a microstrip patch is computed. The numerical results obtained are in good agreement with those published.

A New Kind of Iteration Method for Finding Approximate Periodic Solutions to Ordinary Diferential Equations

In this paper, a new kind of iteration technique for solving nonlinear ordinary differential equations is described and used to give approximate periodic solutions for some well-known nonlinear problems. The most interesting features of the proposed methods are its extreme simplicity and concise forms of iteration formula for a wide range of nonlinear problems.

Finding Periodic Solutions of High Order Duffing Equations via Homotopy Method

This paper presents a detailed analysis of finding the periodic solutions for the high order Duffing equation x^（2n） ＋ g（x） = e（t） （n ≥ 1）. Firstly, we give a constructive proof for the existence of periodic solutions via the homotopy method. Then we establish an efficient and global convergence method to find periodic solutions numerically.

Construction of solitonary and periodic solutions to some nonlinear equations using EXP-function method

This paper applies the EXP-function method to find exact solutions of various nonlinear equations. Tzitzeica- Dodd-Bullough (TDB) equation was selected to illustrate the effectiveness and convenience of the suggested method. More generalized solitonary solutions with free parameters were obtained by suitable choice of the free parameters, and also the obtained solitonary solutions can be converted into periodic solutions.

Study of the emissivity of rough surfaces periodic using the method of coupled waves analysis (CWA) compared with method of geometrical optics approximation (GOA)

We present in this paper a numerical study of the validity limit of the geometrical optics approximation compared with a differential method which is established according to rigorous formalisms based on the electromagnetic theory. The precedent studies show that this method is adapted to the study of diffraction by periodic rough surfaces. We determine by two methods the emissivity of gold and tungsten for surfaces with a rectangular or sinusoidal profile, for a wavelength equal to 0.55 microns. The monochromatic directional emissivity of these surfaces clearly depends on the angle of incidence, the surface profile, height, period and the nature of the material. We perform our calculations by a method of coupled wave analysis (CWA) and a geometric optics method (GOA). The latter method is theoretically valid only when the dimensions of the cavities are very large compared to the wavelength, while the CWA is theoretically correct whatever these dimensions. The main purpose of this work is to investigate the validity limit of GOA compared with CWA. The obtained results for a fixed height of the grating, allowed us to delimit the validity domain of the optic geometrical approximation for the treated cases. Finally, the agreement between the emissivity calculated by the differential method and that given on the basis of the homogenization theory is satisfactory when the period is much smaller than the wavelength.