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Analysis of the Architectural Design Talent Development Direction by Investigating the Employment Status of Architectural Design Graduates
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作者 Cuicui Qin Lijuan Xie +3 位作者 Qiliang Yu Guanhong Chen Binquan Zhang Yani Gao 《Journal of Architectural Research and Development》 2023年第6期23-28,共6页
Based on a comprehensive investigation of the employment status of architectural design graduates at a certain university,this paper analyzes the correctness of the talent development direction of architectural design... Based on a comprehensive investigation of the employment status of architectural design graduates at a certain university,this paper analyzes the correctness of the talent development direction of architectural design in hopes of pro-viding a valuable reference for further teaching reform and strengthening school-enterprise collaboration.The research re-sults show that architectural design is the main choice of graduates,accounting for as high as 63%,and traditional architec-tural design skills continue to be in demand in the market.Employment in fields such as interior design,BIM design,and green architecture is also included.The distribution of job positions for graduates is mainly in the areas of scheme design assistants and construction drawing design,requiring software operation,communication,scheme design,and construction drawing skills.This paper also proposes talent development measures such as optimizing the curriculum,strengthening faculty construction,and deepening school-enterprise collaboration,in order to improve the quality of talent development and the competitiveness of graduates. 展开更多
关键词 Employment Investigation Architectural Design Talents Development Teaching Reform
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New perspectives for investigating respiratory failure induced by cervical spinal cord injury 被引量:1
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作者 Marcel Bonay Stéphane Vinit 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第22期1949-1951,共3页
Traumatic cervical spinal cord injury (SCI), with an annual incidence of 12,000 new cases in USA (NSCISC 2013), causes devastating locomotor and respiratory paralysis and unfortunately compromises the human patien... Traumatic cervical spinal cord injury (SCI), with an annual incidence of 12,000 new cases in USA (NSCISC 2013), causes devastating locomotor and respiratory paralysis and unfortunately compromises the human patient's lifespan. The severity of the injury depends on the degree and the extent of the initial trauma. In fact, respiratory failure is the leading cause of mortality following upper cervical SCI. However, 80% of the injuries are incomplete, allowing some modest spontaneous recovery. To date, no effective treatment is available in order to restore the loss of function. 展开更多
关键词 SCI New perspectives for investigating respiratory failure induced by cervical spinal cord injury CPP
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Use of sensory substitution devices as a model system for investigating cross-modal neuroplasticity in humans 被引量:1
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作者 Amy C.Nau Matthew C.Murphy Kevin C.Chan 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第11期1717-1719,共3页
Blindness provides an unparalleled opportunity to study plasticity of the nervous system in humans.Seminal work in this area examined the often dramatic modifications to the visual cortex that result when visual input... Blindness provides an unparalleled opportunity to study plasticity of the nervous system in humans.Seminal work in this area examined the often dramatic modifications to the visual cortex that result when visual input is completely absent from birth or very early in life(Kupers and Ptito,2014).More recent studies explored what happens to the visual pathways in the context of acquired blindness.This is particularly relevant as the majority of diseases that cause vision loss occur in the elderly. 展开更多
关键词 Use of sensory substitution devices as a model system for investigating cross-modal neuroplasticity in humans BOLD
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A theoretical framework for investigating ecological problems associated with biodiversity conservation in national parks: A case of the Rwenzori Mountains National Park, Uganda
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作者 Moses Muhumuza Martie Sanders Kevin Balkwill 《Open Journal of Ecology》 2013年第2期196-204,共9页
Theoretical frameworks play a vital role in research, spelling out the constructs important in the research area, and the relationships between the constructs. An understanding of the theoretical constructs which unde... Theoretical frameworks play a vital role in research, spelling out the constructs important in the research area, and the relationships between the constructs. An understanding of the theoretical constructs which underpin the research provides researchers with a framework, which enables them to understand when, how and why particular phenomena occur. Depending on the type of research, this either allows them to make reasoned predictions, which can be empirically tested during the research or gives direction for the research if it is open-ended and exploratory. Such frameworks not only guide the questions asked and the design of the research, but also help to interpret the data. If the situation being investigated is very complex, involving numerous interlinked variables, it is often difficult to identify a single theoretical framework that is suitable for a particular study. This article uses the case of human ecological behavioural problems associated with the conservation of biodiversity in the Rwenzori Mountains National Park, to show how a theoretical framework to investigate a complex situation was developed. 展开更多
关键词 Theortical Framework ECOLOGICAL PROBLEMS BIODIVERSITY CONSERVATION investigating NATIONAL Parks Rwenzori
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Investigating “The Third Place” Identity among Chinese Language Students in Newcastle University
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作者 欧阳波 《海外英语》 2016年第22期214-216,共3页
The paper investigated"The Third Place"within Chinese language students' community in the university of Newcastle(Uo N). Through the investigation, critical analysis has been given by comparing the behav... The paper investigated"The Third Place"within Chinese language students' community in the university of Newcastle(Uo N). Through the investigation, critical analysis has been given by comparing the behaviour and performance of two types of Chinese students within the community. Moreover, critical questions have arisen: Is the teacher in the language room really the best catalyst to create"The Third Place"? How should Chinese students make use of wider context to contest their native culture? The paper further described a sociocultural framework which indicates"The Third Place"should not be an isolated knowledge to be learn, but happens through constant information exchange with the outside world and socialising. Critical applications have also been given to guide how to make"The Third Place"occur within Chinese language community smoothly. 展开更多
关键词 "The Third Place" IDENTITY SOCIOCULTURAL framework investigation inter-culture ETC
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A case study investigating the efects of emergency vaccination with Brucella abortus A19 vaccine on a dairy farm undergoing an abortion outbreak in China
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作者 Yu Wang Yan Wang +6 位作者 Qingjie Peng Zhijie Xiang Yingyu Chen Guiqiang Wang Xijuan Wu Aizhen Guo Ian D.Robertson 《Animal Diseases》 2022年第4期246-257,共12页
Brucellosis is an important zoonosis that results in substantial economic losses to the livestock industry through abortions and reduced milk yield.This study investigated an abortion outbreak in a dairy herd and then... Brucellosis is an important zoonosis that results in substantial economic losses to the livestock industry through abortions and reduced milk yield.This study investigated an abortion outbreak in a dairy herd and then explored the efects of emergency vaccination with Brucella abortus A19 vaccine on the incidence of abortion and milk yield.A full dose of vaccine(6×10^(10)—12×10^(10)colony forming units,CFU)was administered subcutaneously to calves and non-pregnant heifers,and a reduced dose(6×10^(8)—12×10^(8)CFU)to adult cows and pregnant replacement heifers.Rose Bengal Test was used to screen Brucella infection status and then positive samples were tested with a C-ELISA.Animals that tested positive for both tests were considered positive to Brucella spp.The animal-level seroprevalence of brucellosis was 23.1%(95%CI:17.0,30.2),and the attributable fraction of abortions in seropositive animals was 89.1%(95%CI:64.3,96.7).The odds of seropositivity were signifcantly higher in cows that aborted compared to cows that calved normally(OR=21.4,95%CI:4.4,168.4).Cows in sheds A2 and C1 were 10.2(95%CI:1.4,128.0)and 17.0(95%CI:2.8,190.3)times more likely to be seropositive than cows in shed B1.Antibodies were not detectable in most heifers 12 months post-vaccination.The efectiveness of the vaccine in preventing abortions was estimated to be 56.8%(95%CI:15.8,77.8)for the entire herd,but increased to 86.7%(95%CI:4.4,98.1)when only primiparous heifers were considered.Furthermore,a signifcant increase in the average herd 305-day milk yield one-year after vaccination was also observed relative to that in the previous three years.It is concluded that emergency vaccination of a dairy herd undergoing an abortion outbreak with the A19 vaccine efectively reduced the incidence of abortion and indirectly increased milk yield one-year after vaccination. 展开更多
关键词 BRUCELLOSIS Outbreak investigation Emergency vaccination Brucella abortus A19 vaccine ABORTION 305-day milk yield
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Investigating the Problems and Proposing Solutions for Rural Residential Buildings in Northwest China
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作者 Zhaobo Zhang Jianqiang Wang Mao Hu 《Journal of Architectural Research and Development》 2022年第2期8-14,共7页
With the increasing income of the rural population in Northwest China,people’s sense of happiness and gain is also increasing.However,the improvement of housing conditions is lagging behind the increasing income leve... With the increasing income of the rural population in Northwest China,people’s sense of happiness and gain is also increasing.However,the improvement of housing conditions is lagging behind the increasing income levels.In recent years,the government and owners have paid much attention to this issue.The local government has successively issued relevant guidelines and policies to encourage owners to reconstruct their houses and improve their housing conditions.Before improving housing conditions,the existing housing problems must be identified.In order to have a comprehensive and in-depth understanding of the problems of rural residential buildings in Northwest China and to propose corresponding solutions,90 representative rural residential buildings of three provinces in Northwest China have been selected for investigation,and mass data have been obtained.Upon analyzing these data,it has been found that there are problems in five aspects of rural residential buildings in Northwest China:architectural style and functional space layout,energy utilization and dissipation,design,construction,as well as structural safety and seismic measures.Valid solutions are proposed to address these problems,which can also provide a reference for the government and enterprises engaged in the architecture,engineering,and construction(AEC)industry in rural areas. 展开更多
关键词 INVESTIGATION PROBLEMS Rural residential buildings SOLUTIONS
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Experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering boundary effect
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作者 Xuwei Wang Yeshuang Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期1072-1084,共13页
The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundar... The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundary effect is conducted,where the hydraulic head difference(DH)varies,and the boundary includes non-loss and soil-loss conditions.Soil samples are filled into seven soil storerooms connected in turn.After evaluation,the variation in content of fine sand(ΔR_(f))and the hydraulic conductivity of soils in each storeroom(C_(i))are analyzed.In the non-loss test,the soil sample filling area is divided into runoff,transited,and accumulated areas according to the negative or positive ΔR_(f) values.ΔR_(f) increases from negative to positive along the seepage path,and Ci decreases from runoff area to transited area and then rebounds in accumulated area.In the soil-loss test,all soil sample filling areas belong to the runoff area,where the gentle-loss,strengthened-loss,and alleviated-loss parts are further divided.ΔR_(f) decreases from the gentle-loss part to the strengthened-loss part and then rebounds in the alleviated-loss part,and C_(i) increases and then decreases along the seepage path.The relationship between ΔR_(f) and Ci is different with the boundary condition.Ci exponentially decreases with ΔR_(f) in the non-loss test and increases with ΔR_(f) generally in the soil-loss test. 展开更多
关键词 Suffusion PERMEABILITY Experimental investigation Boundary effect Horizontal seepage
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Effect of trigger system on experimental dispersion characteristics of active surface wave testing
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作者 Lin Shibin Jeramy C.Ashlock +4 位作者 Zhu Liming Qin Zexiang Li Bo Zhu Xingji Zhai Changhai 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期311-318,共8页
A trigger system is typically employed in active seismic testing to trigger and synchronize multichannel surface wave data acquisition.The effect of the trigger system on the dispersion image of surface waves is empir... A trigger system is typically employed in active seismic testing to trigger and synchronize multichannel surface wave data acquisition.The effect of the trigger system on the dispersion image of surface waves is empirically known to be negligible,however,theoretical explanation regarding the effect of the trigger system is insufficient.This study systematically examines the theory for surface wave dispersion analysis and proves that the effect of the trigger system on a dispersion image is negligible via a solid theoretical explanation.Subsequently,based on the new theoretical explanation,an alternative method that uses only the relative phase difference between sensors to extract dispersion characteristics with better conceptual clarity is proposed.Two active surface wave testing cases are considered to validate the theory and method.The results indicate that(1)an accurate trigger system is not necessary for surface wave data acquisition,and(2)it is unnecessary to assume that the impact point is the generation point of the surface waves for the experimental dispersion analysis. 展开更多
关键词 site investigation surface waves data acquisition DISPERSION
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Experimental investigation on coal pore-fracture variation and fractal characteristics synergistically affected by solvents for improving clean gas extraction
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作者 Feilin Han Sheng Xue +3 位作者 Chunshan Zheng Zhongwei Chen Guofu Li Bingyou Jiang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期413-425,共13页
Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal... Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal synergistically affected by solvents have not been fully understood.Ultrasonic testing,nuclear magnetic resonance analysis,liquid phase mass spectrometry was adopted to comprehensively analyze pore-fracture change characteristics of lean coal treated by combined solvent(NMP and CS_(2)).Meanwhile,quantitative characterization of above changing properties was conducted using geometric fractal theory.Relationship model between permeability,fractal dimension and porosity were established.Results indicate that the end face fractures of coal are well developed after CS2and combined solvent treatments,of which,end face box-counting fractal dimensions range from 1.1227 to 1.4767.Maximum decreases in ultrasonic longitudinal wave velocity of coal affected by NMP,CS_(2)and combined solvent are 2.700%,20.521%,22.454%,respectively.Solvent treatments could lead to increasing amount of both mesopores and macropores.Decrease ratio of fractal dimension Dsis 0.259%–2.159%,while permeability increases ratio of NMR ranges from 0.1904 to 6.4486.Meanwhile,combined solvent could dissolve coal polar and non-polar small molecules and expand flow space.Results could provide reference for solvent selection and parameter optimization of permeability-enhancement technology. 展开更多
关键词 Clean gas extraction Chemical solvent Experimental investigation Fractal characteristics Pore fracture
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Finite Element Simulation Analysis of a Novel 3D-FRSPA for Crawling Locomotion
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作者 Bingzhu Wang Xiangrui Ye 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1401-1425,共25页
A novel three-dimensional-fiber reinforced soft pneumatic actuator(3D-FRSPA)inspired by crab claw and human hand structure that can bend and deform independently in each segment is proposed.It has an omni-directional ... A novel three-dimensional-fiber reinforced soft pneumatic actuator(3D-FRSPA)inspired by crab claw and human hand structure that can bend and deform independently in each segment is proposed.It has an omni-directional bending configuration,and the fibers twined symmetrically on both sides to improve the bending performance of FRSPA.In this paper,the static and kinematic analysis of 3D-FRSPA are carried out in detail.The effects of fiber,pneumatic chamber and segment length,and circular air chamber radius of 3D-FRSPA on the mechanical performance of the actuator are discussed,respectively.The soft mobile robot composed of 3D-FRSPA has the ability to crawl.Finally,the crawling processes of the soft mobile robot on different road conditions are studied,respectively,and the motion mechanism of the mobile actuator is shown.The numerical results show that the soft mobile robots have a good comprehensive performance,which verifies the correctness of the proposedmodel.This work shows that the proposed structures have great potential in complex road conditions,unknown space detection and other operations. 展开更多
关键词 3D-FRSPA bionic structure theoretical modeling crawling application obstacle avoidance analysis numerical investigation
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Auto-parametric resonance of a continuous-beam-bridge model under two-point periodic excitation:an experimental investigation and stability analysis
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作者 Li Yuchun Shen Chao +1 位作者 Liu Wei Li Dong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期445-454,共10页
The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the ... The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the test model is conducted to observe and measure the auto-parametric resonance of a continuous beam under a two-point excitation on columns.The parametric vibration equation is established for the test model using the finite-element method.The auto-parametric resonance stability of the structure is analyzed by using Newmark's method and the energy-growth exponent method.The effects of the phase difference of the two-point excitation on the stability boundaries of auto-parametric resonance are studied for the test model.Compared with the experiment,the numerical instability predictions of auto-parametric resonance are consistent with the test phenomena,and the numerical stability boundaries of auto-parametric resonance agree with the experimental ones.For a continuous beam bridge,when the ratio of multipoint excitation frequency(applied to the columns)to natural frequency of the continuous girder is approximately equal to 2,the continuous beam may undergo a strong auto-parametric resonance.Combined with the present experiment and analysis,a hypothesis of Volgograd Bridge's serpentine vibration is discussed. 展开更多
关键词 auto-parametric resonance continuous beam bridge model two-point excitation experimental investigation stability analysis vibration of Volgograd Bridge
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Comparative study of different machine learning models in landslide susceptibility assessment: A case study of Conghua District, Guangzhou, China
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作者 Ao Zhang Xin-wen Zhao +8 位作者 Xing-yuezi Zhao Xiao-zhan Zheng Min Zeng Xuan Huang Pan Wu Tuo Jiang Shi-chang Wang Jun He Yi-yong Li 《China Geology》 CAS CSCD 2024年第1期104-115,共12页
Machine learning is currently one of the research hotspots in the field of landslide prediction.To clarify and evaluate the differences in characteristics and prediction effects of different machine learning models,Co... Machine learning is currently one of the research hotspots in the field of landslide prediction.To clarify and evaluate the differences in characteristics and prediction effects of different machine learning models,Conghua District,which is the most prone to landslide disasters in Guangzhou,was selected for landslide susceptibility evaluation.The evaluation factors were selected by using correlation analysis and variance expansion factor method.Applying four machine learning methods namely Logistic Regression(LR),Random Forest(RF),Support Vector Machines(SVM),and Extreme Gradient Boosting(XGB),landslide models were constructed.Comparative analysis and evaluation of the model were conducted through statistical indices and receiver operating characteristic(ROC)curves.The results showed that LR,RF,SVM,and XGB models have good predictive performance for landslide susceptibility,with the area under curve(AUC)values of 0.752,0.965,0.996,and 0.998,respectively.XGB model had the highest predictive ability,followed by RF model,SVM model,and LR model.The frequency ratio(FR)accuracy of LR,RF,SVM,and XGB models was 0.775,0.842,0.759,and 0.822,respectively.RF and XGB models were superior to LR and SVM models,indicating that the integrated algorithm has better predictive ability than a single classification algorithm in regional landslide classification problems. 展开更多
关键词 Landslides susceptibility assessment Machine learning Logistic Regression Random Forest Support Vector Machines XGBoost Assessment model Geological disaster investigation and prevention engineering
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Relationship between Kawasaki disease and abdominal pain
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作者 Yan Pan Fu-Yong Jiao 《World Journal of Clinical Cases》 SCIE 2024年第17期2932-2934,共3页
This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral muco... This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral mucosal changes,and swelling of the extremities.This editorial aims to delve into the intricate relationship between KD and abdominal pain,drawing insights from recent research findings to provide a comprehensive understanding and potential avenues for future investigation. 展开更多
关键词 Kawasaki disease Abdominal pain RELATIONSHIP RESEARCH INVESTIGATION
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Systematic investigation of Radix Salviae for treating diabetic peripheral neuropathy disease based on network Pharmacology
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作者 Tao Kang Xiao Qin +1 位作者 Yan Chen Qian Yang 《World Journal of Diabetes》 SCIE 2024年第5期945-957,共13页
BACKGROUND Diabetic peripheral neuropathy(DPN)is a debilitating complication of diabetes mellitus with limited available treatment options.Radix Salviae,a traditional Chinese herb,has shown promise in treating DPN,but... BACKGROUND Diabetic peripheral neuropathy(DPN)is a debilitating complication of diabetes mellitus with limited available treatment options.Radix Salviae,a traditional Chinese herb,has shown promise in treating DPN,but its therapeutic mech-anisms have not been systematically investigated.AIM Radix Salviae(Danshen in pinin),a traditional Chinese medicine(TCM),is widely used to treat DPN in China.However,the mechanism through which Radix Salviae treats DPN remains unclear.Therefore,we aimed to explore the mechanism of action of Radix Salviae against DPN using network pharmacology.METHODS The active ingredients and target genes of Radix Salviae were screened using the TCM pharmacology database and analysis platform.The genes associated with DPN were obtained from the Gene Cards and OMIM databases,a drug-com-position-target-disease network was constructed,and a protein–protein inter-action network was subsequently constructed to screen the main targets.Gene Ontology(GO)functional annotation and pathway enrichment analysis were performed via the Kyoto Encyclopedia of Genes and Genomes(KEGG)using Bioconductor.RESULTS A total of 56 effective components,108 targets and 4581 DPN-related target genes of Radix Salviae were screened.Intervention with Radix Salviae for DPN mainly involved 81 target genes.The top 30 major targets were selected for enrichment analysis of GO and KEGG pathways.CONCLUSION These results suggested that Radix Salviae could treat DPN by regulating the AGE-RAGE signaling pathway and the PI3K-Akt signaling pathway.Therefore,Danshen may affect DPN by regulating inflammation and apoptosis. 展开更多
关键词 Diabetic peripheral neuropathy Radix Salviae Network pharmacology Systematic investigation
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Investigation and Analysis of Main Diseases of Landscape Plants in the Main Urban Area of Lu'an City
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作者 Gao LIU Hao SONG Juanjuan HU 《Plant Diseases and Pests》 2024年第1期18-21,共4页
To figure out the disease occurrence of landscape plants in the main urban area of Lu'an City,the author investigated the disease occurrence of landscape plants in park green space,residential green space,unit att... To figure out the disease occurrence of landscape plants in the main urban area of Lu'an City,the author investigated the disease occurrence of landscape plants in park green space,residential green space,unit attached green space and main road in the area under administration.The survey results showed that there were 29 species of urban landscape plant diseases,mainly powdery mildew and spot diseases.According to the characteristics of the diseases,the causes and problems of the diseases were analyzed,and the corresponding prevention and control measures were put forward. 展开更多
关键词 Landscape plant Disease species INVESTIGATION Status analysis Lu'an City
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Clinical/Behavioral Monitoring of Rodents and Rabbits Undergoing Scientific Experiments
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作者 Luiz Cesar Cavalcanti Pereira Jhônata Willy Rocha Coelho +5 位作者 Hyago da Silva Medeiros Elidio Rita de Cássia dos Passos Ferraz Da Silva João Gabriel Regis Sobral Bárbara Alves de Brito Soledade Leandro Thomaz Vilela Isabele Barbieri Dos Santos 《Open Journal of Veterinary Medicine》 CAS 2024年第5期91-109,共19页
Background: We currently have international and national guidelines regarding the assessment and monitoring of clinical signs and humane endpoints in animals used in teaching and research, which make the performance o... Background: We currently have international and national guidelines regarding the assessment and monitoring of clinical signs and humane endpoints in animals used in teaching and research, which make the performance of these activities mandatory for any experiment and professional working in this area. Assigning the severity of a research experiment is the result of an analysis of records of observations of the animal’s behavior, and clinical signs. The aim of this study was to describe the importance of carrying out a severity assessment associated with clinical and behavioral monitoring of rodents and rabbits during experimentation to maintain the welfare of these animals undergoing scientific research. Methods: The literature search was carried out using the following terms: “Monitoring”;“Humane endpoints”;“Animal welfare”, “Rodents”;“Rabbits”, and as connectors “and”;“or”, in the following databases: PubMed;LILACS/BIREME and SciELO. Results: A total of 987 articles were identified in the databases, and 20 of these studies were included in this review. Conclusions: Humane endpoint protocols and procedure severity tables are of the utmost importance, both from an ethical point and to refine the results of research conducted on laboratory animals. They should be drawn up jointly by the teams responsible for the project and the maintenance of the animals during the research period, and the data obtained should be published so that the scientific community can have access to it, helping to disseminate these practices, as well as helping to draw up new procedures. Monitoring and evaluating the welfare and clinical condition of animals undergoing scientific research procedures is the responsibility of the professors, researchers, veterinarians, and animal facility coordinators. The Ethics Committee on the Use of Animals must monitor all the activities conducted with the animals, by inspecting the experimental procedures and the physical environment of the laboratory animal facility where the animals are housed. 展开更多
关键词 MONITORING Humane Endpoints Animal Welfare Experimental Design Laboratory Animals’ Investigations
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Determination of Liability for Violation of “Sexual Autonomy” and Compensation for Mental Damages
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作者 姚邢 JIANG Lin(Translated) 《The Journal of Human Rights》 2024年第2期347-372,共26页
At the legislative level in China,there has been insufficient theoretical preparation to explicitly include“sexual autonomy”within the scope of general personality rights.In handling the increasing number of dispute... At the legislative level in China,there has been insufficient theoretical preparation to explicitly include“sexual autonomy”within the scope of general personality rights.In handling the increasing number of disputes related to violations of“sexual autonomy,”judicial biases have emerged during the trial process when courts determine the attribute of the right to“sexual autonomy.”This situation necessitates a clear legal analysis of the concept and attributes of“sexual autonomy”to establish its essential attribute as a personality right,and,from the perspective of legal doctrine,enable the justification of the right to“sexual autonomy”as either a general personality right or other personality interests,thereby providing theoretical support for courts to“adjudicate according to law.”By delineating and categorizing instances of violations of“sexual autonomy,”the constitutive elements and fundamental characteristics of such violations can be clarified.By examining the legal norms governing civil litigation and civil litigation associated with criminal cases concerning violations of“sexual autonomy,”the responsibility determination,remedies,and existing regulatory loopholes regarding violations of“sexual autonomy,”especially in cases involving both criminal and civil matters,can be defined.Based on this foundation,the legal basis,determination mechanism,and compensation standards for claiming compensation for mental damages resulting from violations of“sexual autonomy”can be elucidated. 展开更多
关键词 sexual autonomy personality rights VIOLATIONS liability investigation
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Did pediatric drug development advance epilepsy treatment in young patients?It is time for new research goals
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作者 Earl B Ettienne Emilio Russo +2 位作者 Pasquale Striano Jane M Grant-Kels Klaus Rose 《World Journal of Methodology》 2024年第2期65-74,共10页
Modern drugs have changed epilepsy,which affects people of all ages.However,for young people with epilepsy,the framework of drug development has stalled.In the wake of the thalidomide catastrophe,the misconception eme... Modern drugs have changed epilepsy,which affects people of all ages.However,for young people with epilepsy,the framework of drug development has stalled.In the wake of the thalidomide catastrophe,the misconception emerged that for people<18 years of age drugs,including antiseizure medications(ASMs),need separate proof of efficacy and safety,overall called"pediatric drug development".For ASMs,this has changed to some degree.Authorities now accept that ASMs are effective in<18 years as well,but they still require"extrapolation of efficacy,"as if minors were another species.As a result,some of the pediatric clinical epilepsy research over the past decades was unnecessary.Even more importantly,this has hampered research on meaningful research goals.We do not need to confirm that ASMs work before as they do after the 18th birthday.Instead,we need to learn how to prevent brain damage in young patients by preventing seizures and optimize ASMs’uses.Herein we discuss how to proceed in this endeavor. 展开更多
关键词 EPILEPSY Pediatric drug development Therapeutic orphans Antiseizure medications Pediatric investigation plan Clinical pharmacology
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The Effect of a Monatomic Layer on a Surface on the Transition Radiation
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作者 Alexander N. Safronov 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2024年第2期710-723,共14页
The transition radiation of a charged particle crossing the interface of two media having a monatomic impurity layer is investigated. It is shown that at sliding angles of incidence of a particle on the boundary of th... The transition radiation of a charged particle crossing the interface of two media having a monatomic impurity layer is investigated. It is shown that at sliding angles of incidence of a particle on the boundary of the media, the transition radiation is mainly determined by the properties of the surface layer. The possibility of using transition radiation to study the surface of substances is discussed. In addition, due to the hard radiation present in space, this research may be important for the use of light monoatomic layers as a material for satellite antennas, “solar sails” and cover layers in a future space (interstellar) mission. 展开更多
关键词 Relativistic Charged Particle Transition Radiation Monatomic Layer Spectral Angular Distribution of Radiation Sliding Angle Investigation of Thin Films Interstellar Mission
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