Clinical Analysis of Common Irrational Gastroenterology Medication Problems in The Gastroenterology Department

Objective: To investigate and analyze the irrational problems of common gastroenterology medications applied to gastroenterology patients during treatment, and to develop and implement countermeasures. Methods: This study included 60 patients admitted to the Department of Gastroenterology from January 2021 to December 2023 who were randomly divided into a control group (conventional drug management) and an observation group (targeted drug treatment), of 30 cases each. After the implementation of different management methods, the occurrence of irrational drug use and the incidence of adverse reactions between both groups were compared and statistically analyzed. Results: The incidence of irrational medication in the observation group (13.33%) was lower than that in the control group (40.00%) (P < 0.05). The occurrence of adverse reactions in the observation group (10.00%) was lower than that of the control group (36.67%) after treatment (P < 0.05). The observation group had a higher level of satisfaction after treatment (90.00%) as compared to the control group (66.67%) (P < 0.05). Conclusion: Implementation of targeted drug treatment for gastroenterology patients reduced the incidence of irrational medication use, reduced adverse reactions, and improved patient satisfaction.

Bifurcations and chaotic threshold for a nonlinear system with an irrational restoring force

Nonlinear dynamical systems with an irrational restoring force often occur in both science and engineering, and always lead to a barrier for conventional nonlinear techniques. In this paper, we have investigated the global bifurcations and the chaos directly for a nonlinear system with irrational nonlinearity avoiding the conventional Taylor＇s expansion to retain the natural characteristics of the system. A series of transformations are proposed to convert the homoclinic orbits of the unperturbed system to the heteroclinic orbits in the new coordinate, which can be transformed back to the analytical expressions of the homoclinic orbits. Melnikov＇s method is employed to obtain the criteria for chaotic motion, which implies that the existence of homoclinic orbits to chaos arose from the breaking of homoclinic orbits under the perturbation of damping and external forcing. The efficiency of the criteria for chaotic motion obtained in this paper is verified via bifurcation diagrams, Lyapunov exponents, and numerical simulations. It is worthwhile noting that our study is an attempt to make a step toward the solution of the problem proposed by Cao Q J et al. （Cao Q J, Wiercigroch M, Pavlovskaia E E, Thompson J M T and Grebogi C 2008 Phil. Trans. R. Soe. A 366 635）.

Development of the Irrational Belief Test for Nurses (IBTN): Examination of Reliability and Validity

[Purpose]: The purpose of this study is to develop irrational belief test for nurses, and to examine reliability and validity. [Method]: In study 1, The Irrational belief test for nurses was developed based JIBT-20 (mori et al., 1994) of previous studies. And for the nurse (N = 96, 5 male, 91 female), carried out preliminary investigation, created the provisional version of the Irrational belief test for nurses, and examined factor structure and internal consistency. In study 2, for the nurse (N = 541, 21 male, 520 female) examined validity based on JIBT-20 (Japanese Irrational Belief Test), MBI (Maslach Burnout Inventory), ATQ-R Japanese version (Automatic Thoughts Questionnare-Revised), and for the nurse (N = 91, 3 male, 88 female) examined a test-retest reliability four weeks afterward before long. [Result]: As a result of the explanatory factor analysis by a maximum likelihood estimation and promax rotation, 28-item 7 factors were extracted and was named a “patient belief”, “self-expectation”, “avoidance”, “self-inhibition”, “Ethical blame”, “helplessness”, and “dependence”. Moreover, as a result of conducting confirmation factor analysis, the hypothetical model obtained by explanatory factor analysis fitted (GFI = 0.89, AGFI = 0.86). About the reliability of the measure, a Cronbach’s alpha coefficient is 0.68 - 0.82, and a test-retest reliability is 0.64 and reliability is affirmed. About construct validity was checked correlation with JIBT-20, and about criterion validity was checked the correlation with MBI and ATQ-R Japanese-translation version. [Conclusion]: It is suggested that reliability and validity are verified and the irrational belief test for nurses is a useful measure. The developed test can be used to measure the irrational belief in the context of burnout in nurses.

Intramolecular vibrational dynamical barrier due to extremely irrational couplings

The intramolecular vibrational dynamics due to extremely irrational couplings is demonstrated by contrast to the resonance couplings, for the three-mode case of H2O as an example. The extremely irrational couplings are shown to impose such strong hindrance to intramolecular vibrational relaxation （IVR） that they act as barriers. They restrict the direct action/energy transfer between the two stretching modes, though they allow the transfer between a stretching and a bending modes. In contrast, the resonance is more mediated by the bending mode and leads to chaotic IVR. It is also shown that there is a region in the dynamical space in which resonance and extremely irrational couplings coexist.

Analysis on Irrational Decision Making of Tobacco Family Farmers from the Perspective of Optimal Scale of Efficiency

The larger the difference between the willingness scale of tobacco family farmers and the optimal scale of efficiency,the greater the degree of irrationality,and the higher the decision making risk.With the aid of DEA model,this study calculated the optimal scale of efficiency of Guiyang tobacco family farms.Using the ratio of willingness scale and efficiency optimal scale,it measured the degree of irrationality of family farmers.In addition,with the help of multiple linear regression model,it explained the irrational decision making mechanism of family farmers.Finally,it made a portrait of farmers who tend to make irrational decisions,to find specific farmers and guide them in their production and operation,reduce the risk of planting scale decision making and stabilize the sustainable development of the tobacco industry.

Periodic, Irrational and Transcendental Numbers in the Factorial Series

The main aim of the article is to investigate the irrational and transcendental properties of certain real numbers by means of the factorial series and the factorial number system. The difference between the factorial series and the factorial system is that the factorial series does not set an upper bound at a given place after the radix point, while in the factorial system (i – 1) is the maximal possible value for ri after the radix point. I give an extended definition of periodic numbers, and show the relationship between periodic and irrational numbers. I prove the transcendence of e by means of the factorial series and the factorial number system.

Irrational Narration in The Black Cat

Edgar Allan Poe,a writer of American Romantic period,is a forerunner in the use of irrational narration,especially in his dark tales,opening up a new approach for literature.Whether from narration perspective,plot or theme,The Black Cat,one of his masterpiece,is the typical manifestation of this narration.

On the Irrational Narration in The Black Cat

Edgar Allan Poe is one of the representative writers in American Dark Romanticism.Different from his contemporaries,the majority of Poe's short stories are characterized by irrational narration.Whether from narration technique or elements,The Black Cat is the best elucidation of such narration.Thus,this thesis is devoted to a condensed study of irrational narration in The Black Cat,holding views that Poe's contribution in promoting the development of American literature and continuing the American dream is profound and significant.

Pharmacy intervention of irrational medical orders on pharmacy intravenous admixture services of outpatient and emergency departments in Fujian Provincial Hospital

In the present study, we aimed to analyze the irrational medical orders and evaluate the effect of pharmacy intervention on pharmacy intravenous admixture services of outpatient and emergency departments in our hospital. The irrational medical orders of PIVAS at the outpatient and emergency departments were retrospectively analyzed in Jun. 2015. We strengthened the pharmacy intervention on irrational medical orders since July 2015. All the cases were selected by systematic sampling method. Cased studied in Jun. 2015 served as the control group, whereas those studied in Jan. 2016 served as the intervention group. The irrational rate and the irrational number of daily average were compared between the control group and intervention group. The common type of irrational outpatient and emergency intravenous orders mainly included irrational use of solvents, irrational dosing interval and inappropriate compatibility of drugs. The irrational rate was reduced from 17.4% to 3.3% （P〈0.01）, and the irrational number of daily average was decreased from 5.23 to 1.00 （P〈0.01）. Pharmacy intervention can reduce the irrational rate of medical orders in our hospital, which is of great significance to promote rational drug use and improve medical quality.

A novel smooth and discontinuous oscillator with strong irrational nonlinearities

In this paper,we propose a novel nonlinear oscillator with strong irrational nonlinearities having smooth and discontinuous characteristics depending on the values of a smoothness parameter.The oscillator is similar to the SD oscillator,originally introduced in Phys Rev E 69(2006).The equilibrium stability and the complex bifurcations of the unperturbed system are investigated.The bifurcation sets of the equilibria in parameter space are constructed to demonstrate transitions in the multiple well dynamics for both smooth and discontinuous regimes.The Melnikov method is employed to obtain the analytical criteria of chaotic thresholds for the singular closed orbits of homoclinic,homo-heteroclinic,cuspidal heteroclinic and tangent homoclinic orbits of the perturbed system.

The Legal Regulation of Irrational Elements in the Operations of Boards of Directors

The operating processes of boards of directors are delicate and complex, so corporate legislation cannot simply equate board structure law with board governance law. It is therefore necessary to start from China＇s actual conditions and grasp the operating processes of Chinese boards with a sober appreciation of the irrational elements in their operating mechanisms. Board governance has entered a new stage of institutionalization, and the law should shift from its emphasis on structure to give equal attention to structure and process in optimizing institutional structure. In the construction of board operating mechanisms, we should treat differently such ＂living laws＂ as customs, experiences and traditions, give full play to the functionality of boards＇ strategic choices, and provide legal regulation of irrational elements, so as to distinguish between different roles, develop consensus, select strong points and improve efficiency. We should build control over board operational procedures, improve the system of functional allocation, correct assessment mechanisms, develop a mechanism for judicial scrutiny of the affective relationships in society and curb such behavioral tendencies as relational identity, structural bias and group polarization, with a view to controlling such ＂living laws＂ within the framework of the basic values and principles of board governance.

IRRATIONAL ROTATION c-ALGEBRA FOR GROUPOID c-ALGEBRA

This paper characterizes the irrational rotaion C-algebra associated with the Toeplitz Calgebraover the L-shaped domain in in the sense of the maximal radical series, which is an isomorphism invariant.

Do Irrational Investors Destabilize？

In a financial market where all investors have valuable private informa- tion, full rationality requires that investors have an unlimited ability of figuring out the equilibrium model. Instead, I assume that due to a lack of knowledge or experience, some investors do not know the equilibrium model and use only their private infor- mation in forming their demand. By investigating the investment behavior of these ＂boundedly rational＂ investors and contrasting it with that of the rational ones, I find that in a market where the two kinds of investors coexist, it is the boundedly rational investors who contribute to price stability. The welfare implication is that, although each investor benefits from conditioning his asset demand on the information transmit- ted by the equilibrium price, it can happen that all investors lose by doing so because the equilibrium price becomes too volatile.

Study on Herding Equilibrium of Irrational Informed Trader

This paper studies the connection between the irrational behavior of traders and the herding equilibrium of informed traders in security market. At first, we set up the trading system on the condition of market maker, establish a trading model of perfectly rational traders, and then define herding equilibrium. Second, we extend the model using two parameters, and find the critical points of irrational traders when they reach the herding equilibrium. The result indicates that herding never occurs in market if all the traders are perfectly rational. If consider their irrational factor, it maybe arouse herding. Besides, along with the number of traders who make the same trading strategies increasing, the two critical points show some rules.

The Relationship between Dimensions of Emerging Adulthood and Behavioral Problems among Chinese Emerging Adults: The Mediating Role of Physical Activity and Self- Control

Emerging adulthood(EA)is a critical stage of life to develop and sustain a healthy lifestyle,which is also a time of vulnerability to poor physical and mental health outcomes.In this study,we conducted a path analysis(N=1326)to examine associations among four dimensions of EA,levels of regular physical activity(PA),self-control,MPA tendency and irrational procrastination.Results found:1)higher levels of PA predicted both MPA tendency(β=−0.08,95%CI:−0.11 to−0.06,p<0.001)and irrational procrastination(β=−0.01,95%CI:−0.17 to−0.008,p<0.01)indirectly via self-control;2)Instability(β=0.13,95%CI:0.08 to 0.18,p<0.01)and Responsibility(β=−0.06,95%CI:−0.10 to−0.08,p=0.03)exerted direct effects on irrational procrastination and Instability also indirectly predicted irrational procrastination via MPA tendency(β=0.03,95%CI:0.02 to 0.05,p<0.01).These findings proved that perceived features of EA are linked to behavioral problems and supported that regular PA plays a crucial role to protect mental health.

The Level of Knowledge, Behaviors, and Attitudes on Rational Use of Drugs of Patients Who Applied to the Family Health Center in Istanbul, Türkiye: A Cross-Sectional Study

Background: This study, it was aimed to determine the level of knowledge, attitudes, and behaviors of patients who applied to a family health center about the rational use of drugs. Irrational use of drugs is a major problem worldwide. WHO reports that half of the patients do not use their drugs correctly. Methods: This cross-sectional study was conducted between 1 October 2017 and 30 November 2018 at Istanbul Fatih Family Health Center No 7. The sample size was determined as 301 people selected by systematic sampling method from patients aged 18 and older. Results: The mean age of the participants was 53.8% ± 16.8%, 59.8% were female, 62.5% were married, and 52.5% were primary school graduates. 63.9% of the participants knew the names of the drugs they used, and 79.9% of them knew the indication for use. 89% of individuals check the expiry date of the drugs before using them, and 83.1% read the drug prospectus. 84% of the participants support the prohibition of using over-the-counter drugs. Conclusion: The level of knowledge of the participants about the rational use of drugs is above the societal average. However, some issues need more awareness. The high level of rational use of drugs awareness of physicians and pharmacists will also strengthen the rational use of drugs and indirectly increase the awareness of the public.

固原县自然条件概况

固原县位于黄土高原西北部，属温带半干旱黄土丘陵森林草原向干草原过渡地区．具有土地辽阔，水热组合多样，天然草场面积大等有利条件．同时具有土地利用不合理，灾害频繁，天然草场退化．森林覆盖率低等不利条件．

Antibiotics/antibacterial drug use, their marketing and promotion during the post-antibiotic golden age and their role in emergence of bacterial resistance

During the post-antibiotic golden age, it has seen a massive antibiotic/antibacterial production and an increase in irrational use of these few existing drugs in the medical and veterinary practice, food industries, tissue cultures, agriculture and commercial ethanol production globally. The irrational drug use has been further exacerbated by the increased marketing and promotion of these drugs by the pharmaceutical companies thus increasing their accessibility in the public and hence their improper use. The lack of production and introduction of the newer and effective antibiotic/antibacterial drugs in clinical practice in the post-antibiotic golden age has seen an increase in the emergence of the resistant pathogenic bacterial infections creating a significant problem in the global health of humankind. The massive productions of the antibiotic/antibacterial drugs have contributed to the poor disposal of these drugs and hence many of them are discharged in various water bodies contributing to the environmental antibiotic/antibacterial drug pollution. In the environment, these drugs exert pressure on the environmental bacteria by destroying useful bacteria that are responsible for the recycling of the organic matter and as well as promoting the selection of the resistant pathogenic bacteria that can spread in human and animal population thus causing an increase in the observed bacterial disease burden and hence a significant global public health problem. The resistant bacterial diseases lead to the high cost, increased occurrence of adverse drug reactions, prolonged hospitalization, the exposure to the second- and third-line drugs like in MDR-TB and XDR-TB that leads to toxicity and deaths as well as the increased poor production in agriculture and animal industry and commercial ethanol production.

Analysis of the periodic solutions of a smooth and discontinuous oscillator

In this paper, the periodic solutions of the smooth and discontinuous （SD） oscillator, which is a strongly irra- tional nonlinear system are discussed for the system having a viscous damping and an external harmonic excitation. A four dimensional averaging method is employed by using the complete Jacobian elliptic integrals directly to obtain the perturbed primary responses which bifurcate from both the hyperbolic saddle and the non-hyperbolic centres of the un- perturbed system. The stability of these periodic solutions is analysed by examining the four dimensional averaged equa- tion using Lyapunov method. The results presented herein this paper are valid for both smooth （e 〉 0） and discontin- uous （ce = 0） stages providing the answer to the question why the averaging theorem spectacularly fails for the case of medium strength of external forcing in the Duffing system analysed by Holmes. Numerical calculations show a good agreement with the theoretical predictions and an excellent efficiency of the analysis for this particular system, which also suggests the analysis is applicable to strongly nonlinear systems.