With the rapid development of urban agglomerations in northwest arid and semiarid regions of China, the scope of the urban heat island(UHI) effect has gradually expanded and gradually connected, and has formed a regio...With the rapid development of urban agglomerations in northwest arid and semiarid regions of China, the scope of the urban heat island(UHI) effect has gradually expanded and gradually connected, and has formed a regional heat island(RHI) with a larger range of impact to the regional environment. However, there are few studies on the heat island effect of urban agglomerations in arid and semiarid regions, so this paper selects the urban agglomeration of Hohhot, Baotou and Ordos(HBO) of Inner Mongolia, China as the study area. Based on the 8-day composite Moderate-resolution Imaging Spectroradiometer(MODIS) surface temperature data(156scenes in all) and land use maps for 2005, 2010, and 2015, we analyze the spatiotemporal distributions of regional heat(cool) islands(RH(C)I) and the responses of surface temperatures to land-use changes in the diurnal and interannual surface cities. The results showed that: 1) from 2005 to 2015, urban areas showed the cold island effect during the day, with the area of the cold island showing a shrinking feature;at night, they showed the heat island effect, with the area of the heat island showing a first decrease and then an increase.2) From 2005 to 2015, the land development(unutilized land to building land) brings the greatest temperature increase(ΔT = 1.36°C)during the day, while the greatest temperature change at night corresponds to the conversion of cultivated land to building land(ΔT =0.78°C) exhibited the largest changes at night. From 2010 to 2015, the land development(grassland to building land) bring the greatest temperature increase(ΔT = 0.85°C) during the day, while the great temperature change at night corresponds to the conversion of water areas to building land(ΔT = 1.38°C) exhibited the largest changes at night. Exploring the spatial and temporal evolution of surface urban heat(cool) islands in urban agglomerations in arid and semiarid regions will help to understand the urbanization characteristics of urban agglomerations and provide a reference for the formulation of policies for the coordinated and healthy development of the region and co-governance of regional environmental problems.展开更多
由海事咨询计划顾问、阿拉斯加大学费尔班克斯分校渔业与海洋科学学院教授特里·约翰逊撰写的《The Bering Sea and Aleutian Island:Region of Wonders》一书于2003年由阿拉斯加海洋基金出版。该书一共分为八章,共191页,450多张彩...由海事咨询计划顾问、阿拉斯加大学费尔班克斯分校渔业与海洋科学学院教授特里·约翰逊撰写的《The Bering Sea and Aleutian Island:Region of Wonders》一书于2003年由阿拉斯加海洋基金出版。该书一共分为八章,共191页,450多张彩色照片、地图等图件,88条参考文献,对白令海和阿留申群岛及其周边区域的水文地理特征进行了详细的描述。包括地理要素、自然环境、人文生态,以及资源能源等方面的内容。特里·约翰逊梳理了白令海和阿留申群岛区域水文地理探索的新成果,对中国寒区海域认识和研究具有重要的参考价值。展开更多
The local temperature is one of the major climatic elements to record the changes in the atmospheric environment brought about by industrialization, increasing population and massive urbanization. The present study de...The local temperature is one of the major climatic elements to record the changes in the atmospheric environment brought about by industrialization, increasing population and massive urbanization. The present study deals with the annual and seasonal temperature trends and anomalies for maximum, minimum and mean temperatures of the four meteorological stations of the National Capital Region (NCR) of India namely Safdarjung, Palam, Gurgaon and Rohtak for the past few decades and their association with the development through urbanization processes. The annual mean maximum temperature did not show any specific trend;however a consistent increasing trend was seen in the annual mean minimum temperatures indicating an overall warming trend over the NCR especially after 1990. This warming trend is contrary to the cooling trend observed by earlier studies till 1980’s in various other cities of India including Delhi. However, the temperature trends in annual mean minimum temperatures reported in various countries (USA, Turkey, Italy, etc.) across the world showed warming trends to be associated to the urbanization process of the cities also. The current warming trends in temperature in the NCR Delhi based on the annual mean minimum temperatures have thus been supported by the trends in other parts of the world and could be utilized to infer the development process in this region. The urbanization pattern within Delhi is reflected by the trends of differences in annual mean minimum temperature of the two stations within the city namely Safdarjung and Palam. The significance of the warming trends of the annual minimum temperature for the urban heat island effect is also discussed.展开更多
Based on detailed geological and geomorphological mapping, sampling and micro-palaeontological determinations, both of the alpine and neogene formations, new data have been derived for Spetses Island (SW Aegean). The ...Based on detailed geological and geomorphological mapping, sampling and micro-palaeontological determinations, both of the alpine and neogene formations, new data have been derived for Spetses Island (SW Aegean). The applied methodology provided results on the paleogeographic evolution for Spetses Island and the nearby land of Argolida peninsula as well. Based mainly on characteristic nannofossils, a Miocene age of the post-alpine formations is determined. It is the first time that miocene formations have been identified, not only in Spetses Island and Argolida, but in the whole area of Peloponnesus, where only Plio-pleistocene deposits have been described. This work also leads to the conclusion that Spetses Island is attached to the Argolida peninsula, forming an independent paleogeographic unit since Upper Miocene.展开更多
Ly Son (Quang Ngai province) and Phu Quy (Binh Thuan province) are two island districts in Vietnam that have similar natural characteristics;both are facing the issues of sustainable economic development. This researc...Ly Son (Quang Ngai province) and Phu Quy (Binh Thuan province) are two island districts in Vietnam that have similar natural characteristics;both are facing the issues of sustainable economic development. This research applied Man-Kendall model to estimate the trend of some socio-economic elements in these two island districts that have been collected during the period of 2002-2018. In general, socio-economic factors showed a tendency to increase recently. Ly Son island district has faster growth rate than that of Phu Quy because Phu Quy is farther from the mainland, more difficult to access and this island district does not own distinct local products. However, with the current development speed, Ly Son is facing several consequences such as insufficient water sources to meet the water demand and security instability due to the increasing number of visitors to the island. This research also proposed that, in order to sustainably develop the two island districts, there should be a specific structure for economic development orientation among sectors based on phased schedule. More importantly, tourism development planning should take capacity into consideration. Fishing practices should pay attention to methods and fishing equipment. Infrastructure investment for environmental protection as well as advocacy program to minimize the use of plastic bags should be done on a regular basis.展开更多
Aim: To investigate the methylation status of the deleted in azoospermia 1(DAZ1) gene promoter region in different cell types. Methods: Using CpG island Searcher software, a CpG island was found in the promoter re...Aim: To investigate the methylation status of the deleted in azoospermia 1(DAZ1) gene promoter region in different cell types. Methods: Using CpG island Searcher software, a CpG island was found in the promoter region of the DAZ1 gene. The methylation status of this region was analyzed in sperm and leukocytes by bisulfited sequencing. Results: The methylation status of the CpG island in the DAZ1 gene promoter region differed in leukocytes and sperm: it was methylated in leukocytes, but unmethylated in sperm. Conclusion: A differentially methylated region of the DAZ1 gene exists in spermatic and somatic cells, suggesting that methylation of this region may regulate DAZ1 gene expression in different tissues. (Asian J Androl 2006 Jan; 8:61-67 )展开更多
Research on carrying capacity, aiming at maintaining the limited ability of the Earth's life supporting system to sustain human development, requires a comprehensive and ecosystem-based approach to monitor and assess...Research on carrying capacity, aiming at maintaining the limited ability of the Earth's life supporting system to sustain human development, requires a comprehensive and ecosystem-based approach to monitor and assess the localized sustainability of coupled social and ecological systems. A definition termed the ecosystem-based carrying capacity of island(EBCCI) was developed in this paper of which the indices of fundamental and realized carrying capacities of island(FCCI and RCCI) were highlighted to emphasize the inter-dependencies between social systems and ecological systems. In order to avoid the difficulties and uncertainties of direct assessment, the related assessment model was established on the basis of synthetic evaluation of inherent and external factors affecting the EBCCI. The southern Miaodao Archipelago(SMA) located in the intersection of the Bohai Sea and the Yellow Sea, China, was taken as a typical example to acquire integrated recognition of the island ecosystem and its carrying capacity so as to discuss its sustainable development. The index scores of FCCI and RCCI in the SMA were 0.818 5 and 0.712 9 out of 1.0, respectively, with acceptable uncertainties. The results showed a relatively well capacity to sustain progress and relatively well realization of the carrying capacity of island ecosystem, owing to a well capacity of ecologically regulating, general performance of both ecologically supporting and resource provisioning, and a relatively high level of social supporting system. The study implied that it was critical to optimize the inter-dependencies and to sustain the relative balance between social systems and ecological systems so as to improve the RCCI and further facilitate the sustainability of SMA. The approach proposed in this paper provides a powerful tool which is well applicative to the regional level of an oceanic island or archipelago to study the sustainable development and can be further popularized to the coastal zone.展开更多
AIM:To evaluate the in vitro effect of amoxicillin and clarithromycin on the cag pathogenicity island(cag PAI).METHODS:One hundred and forty-nine clinical isolates of Helicobacter pylori(H.pylori)cultured from gastric...AIM:To evaluate the in vitro effect of amoxicillin and clarithromycin on the cag pathogenicity island(cag PAI).METHODS:One hundred and forty-nine clinical isolates of Helicobacter pylori(H.pylori)cultured from gastric biopsies from 206 Colombian patients with dyspeptic symptoms from a high-risk area for gastric cancer were included as study material.Antimicrobial susceptibility was determined by the agar dilution method.Resistant isolates at baseline and in amoxicillin and clarithromycin serial dilutions were subjected to genotyping(cagA,vacA alleles s and m),Glu-Pro-Ile-Tyr-Ala(EPIYA)polymerase chain reaction and random amplified polymorphic DNA(RAPD).Images of the RAPD amplicons were analyzed by Gel-Pro Analyzer 4.5program.Cluster analyses was done using SPSS 15.0statistical package,where each of the fingerprint bands were denoted as variables.Dendrograms were designed by following Ward’s clustering method and the estimation of distances between each pair of H.pylori isolates was calculated with the squared Euclidean distance.RESULTS:Resistance rates were 4%for amoxicillin and 2.7%for clarithromycin with 2%double resistances.Genotyping evidenced a high prevalence of the genotype cagA-positive/vacA s1m1.The 3’region of cagA gene was successfully amplified in 92.3%(12/13)of the baseline resistant isolates and in 60%(36/60)of the resistant isolates growing in antibiotic dilutions.Upon observing the distribution of the number of EPIYA repetitions in each dilution with respect to baseline isolates,it was found that in 61.5%(8/13)of the baseline isolates,a change in the number of EPIYA repetitions lowered antibiotic pressure.The gain and loss of EPIYA motifs resulted in a diversity of H.pylori subclones after bacterial adjustment to changing conditions product of antibiotic pressure.RAPD PCR evidenced the close clonal relationship between baseline isolates and isolates growing in antibiotic dilutions.CONCLUSION:Antibiotic pressure does not induce loss of the cag pathogenicity island,but it can leadin most cases-to genetic rearrangements within the3’region cagA of the founding bacteria that can affect the level of tyrosine phosphorylation impacting on its cellular effects and lead to divergence of cagA-positive subclones.展开更多
From the perspectives of hotel road profile,orientation of plant color combination,interpretation of Cultural eco-elements,and landscape design of Embrace Sea Villas Hotel was taken for example to explore the ways of ...From the perspectives of hotel road profile,orientation of plant color combination,interpretation of Cultural eco-elements,and landscape design of Embrace Sea Villas Hotel was taken for example to explore the ways of demonstrating regional cultural characteristics in hotel landscape designs on Hainan Island. Eco-design techniques of tropical landscapes were combined to facilitate the formation of harmonious holiday resort images on the island,and enhance the public acceptance of the characteristic vacation culture of Hainan.展开更多
文摘With the rapid development of urban agglomerations in northwest arid and semiarid regions of China, the scope of the urban heat island(UHI) effect has gradually expanded and gradually connected, and has formed a regional heat island(RHI) with a larger range of impact to the regional environment. However, there are few studies on the heat island effect of urban agglomerations in arid and semiarid regions, so this paper selects the urban agglomeration of Hohhot, Baotou and Ordos(HBO) of Inner Mongolia, China as the study area. Based on the 8-day composite Moderate-resolution Imaging Spectroradiometer(MODIS) surface temperature data(156scenes in all) and land use maps for 2005, 2010, and 2015, we analyze the spatiotemporal distributions of regional heat(cool) islands(RH(C)I) and the responses of surface temperatures to land-use changes in the diurnal and interannual surface cities. The results showed that: 1) from 2005 to 2015, urban areas showed the cold island effect during the day, with the area of the cold island showing a shrinking feature;at night, they showed the heat island effect, with the area of the heat island showing a first decrease and then an increase.2) From 2005 to 2015, the land development(unutilized land to building land) brings the greatest temperature increase(ΔT = 1.36°C)during the day, while the greatest temperature change at night corresponds to the conversion of cultivated land to building land(ΔT =0.78°C) exhibited the largest changes at night. From 2010 to 2015, the land development(grassland to building land) bring the greatest temperature increase(ΔT = 0.85°C) during the day, while the great temperature change at night corresponds to the conversion of water areas to building land(ΔT = 1.38°C) exhibited the largest changes at night. Exploring the spatial and temporal evolution of surface urban heat(cool) islands in urban agglomerations in arid and semiarid regions will help to understand the urbanization characteristics of urban agglomerations and provide a reference for the formulation of policies for the coordinated and healthy development of the region and co-governance of regional environmental problems.
文摘由海事咨询计划顾问、阿拉斯加大学费尔班克斯分校渔业与海洋科学学院教授特里·约翰逊撰写的《The Bering Sea and Aleutian Island:Region of Wonders》一书于2003年由阿拉斯加海洋基金出版。该书一共分为八章,共191页,450多张彩色照片、地图等图件,88条参考文献,对白令海和阿留申群岛及其周边区域的水文地理特征进行了详细的描述。包括地理要素、自然环境、人文生态,以及资源能源等方面的内容。特里·约翰逊梳理了白令海和阿留申群岛区域水文地理探索的新成果,对中国寒区海域认识和研究具有重要的参考价值。
文摘The local temperature is one of the major climatic elements to record the changes in the atmospheric environment brought about by industrialization, increasing population and massive urbanization. The present study deals with the annual and seasonal temperature trends and anomalies for maximum, minimum and mean temperatures of the four meteorological stations of the National Capital Region (NCR) of India namely Safdarjung, Palam, Gurgaon and Rohtak for the past few decades and their association with the development through urbanization processes. The annual mean maximum temperature did not show any specific trend;however a consistent increasing trend was seen in the annual mean minimum temperatures indicating an overall warming trend over the NCR especially after 1990. This warming trend is contrary to the cooling trend observed by earlier studies till 1980’s in various other cities of India including Delhi. However, the temperature trends in annual mean minimum temperatures reported in various countries (USA, Turkey, Italy, etc.) across the world showed warming trends to be associated to the urbanization process of the cities also. The current warming trends in temperature in the NCR Delhi based on the annual mean minimum temperatures have thus been supported by the trends in other parts of the world and could be utilized to infer the development process in this region. The urbanization pattern within Delhi is reflected by the trends of differences in annual mean minimum temperature of the two stations within the city namely Safdarjung and Palam. The significance of the warming trends of the annual minimum temperature for the urban heat island effect is also discussed.
文摘Based on detailed geological and geomorphological mapping, sampling and micro-palaeontological determinations, both of the alpine and neogene formations, new data have been derived for Spetses Island (SW Aegean). The applied methodology provided results on the paleogeographic evolution for Spetses Island and the nearby land of Argolida peninsula as well. Based mainly on characteristic nannofossils, a Miocene age of the post-alpine formations is determined. It is the first time that miocene formations have been identified, not only in Spetses Island and Argolida, but in the whole area of Peloponnesus, where only Plio-pleistocene deposits have been described. This work also leads to the conclusion that Spetses Island is attached to the Argolida peninsula, forming an independent paleogeographic unit since Upper Miocene.
文摘Ly Son (Quang Ngai province) and Phu Quy (Binh Thuan province) are two island districts in Vietnam that have similar natural characteristics;both are facing the issues of sustainable economic development. This research applied Man-Kendall model to estimate the trend of some socio-economic elements in these two island districts that have been collected during the period of 2002-2018. In general, socio-economic factors showed a tendency to increase recently. Ly Son island district has faster growth rate than that of Phu Quy because Phu Quy is farther from the mainland, more difficult to access and this island district does not own distinct local products. However, with the current development speed, Ly Son is facing several consequences such as insufficient water sources to meet the water demand and security instability due to the increasing number of visitors to the island. This research also proposed that, in order to sustainably develop the two island districts, there should be a specific structure for economic development orientation among sectors based on phased schedule. More importantly, tourism development planning should take capacity into consideration. Fishing practices should pay attention to methods and fishing equipment. Infrastructure investment for environmental protection as well as advocacy program to minimize the use of plastic bags should be done on a regular basis.
文摘Aim: To investigate the methylation status of the deleted in azoospermia 1(DAZ1) gene promoter region in different cell types. Methods: Using CpG island Searcher software, a CpG island was found in the promoter region of the DAZ1 gene. The methylation status of this region was analyzed in sperm and leukocytes by bisulfited sequencing. Results: The methylation status of the CpG island in the DAZ1 gene promoter region differed in leukocytes and sperm: it was methylated in leukocytes, but unmethylated in sperm. Conclusion: A differentially methylated region of the DAZ1 gene exists in spermatic and somatic cells, suggesting that methylation of this region may regulate DAZ1 gene expression in different tissues. (Asian J Androl 2006 Jan; 8:61-67 )
基金The Special Project of Science and Technology Fundamental Work from the Ministry of Science and Technology of China under contract No.2012FY112500the National Natural Science Foundation of China under contract No.41206111
文摘Research on carrying capacity, aiming at maintaining the limited ability of the Earth's life supporting system to sustain human development, requires a comprehensive and ecosystem-based approach to monitor and assess the localized sustainability of coupled social and ecological systems. A definition termed the ecosystem-based carrying capacity of island(EBCCI) was developed in this paper of which the indices of fundamental and realized carrying capacities of island(FCCI and RCCI) were highlighted to emphasize the inter-dependencies between social systems and ecological systems. In order to avoid the difficulties and uncertainties of direct assessment, the related assessment model was established on the basis of synthetic evaluation of inherent and external factors affecting the EBCCI. The southern Miaodao Archipelago(SMA) located in the intersection of the Bohai Sea and the Yellow Sea, China, was taken as a typical example to acquire integrated recognition of the island ecosystem and its carrying capacity so as to discuss its sustainable development. The index scores of FCCI and RCCI in the SMA were 0.818 5 and 0.712 9 out of 1.0, respectively, with acceptable uncertainties. The results showed a relatively well capacity to sustain progress and relatively well realization of the carrying capacity of island ecosystem, owing to a well capacity of ecologically regulating, general performance of both ecologically supporting and resource provisioning, and a relatively high level of social supporting system. The study implied that it was critical to optimize the inter-dependencies and to sustain the relative balance between social systems and ecological systems so as to improve the RCCI and further facilitate the sustainability of SMA. The approach proposed in this paper provides a powerful tool which is well applicative to the regional level of an oceanic island or archipelago to study the sustainable development and can be further popularized to the coastal zone.
基金Supported by The Administrative Department on Science and Innovation of the Republic of Colombia-COLCIENCIAS,No.RC-1106-408-20549,RC-1106-493-26237its program:Jóvenes Investigadores e Innovadores"Virginia Gutiérrez de Pineda",and by the Universidad del Valle,Cali,Colombia
文摘AIM:To evaluate the in vitro effect of amoxicillin and clarithromycin on the cag pathogenicity island(cag PAI).METHODS:One hundred and forty-nine clinical isolates of Helicobacter pylori(H.pylori)cultured from gastric biopsies from 206 Colombian patients with dyspeptic symptoms from a high-risk area for gastric cancer were included as study material.Antimicrobial susceptibility was determined by the agar dilution method.Resistant isolates at baseline and in amoxicillin and clarithromycin serial dilutions were subjected to genotyping(cagA,vacA alleles s and m),Glu-Pro-Ile-Tyr-Ala(EPIYA)polymerase chain reaction and random amplified polymorphic DNA(RAPD).Images of the RAPD amplicons were analyzed by Gel-Pro Analyzer 4.5program.Cluster analyses was done using SPSS 15.0statistical package,where each of the fingerprint bands were denoted as variables.Dendrograms were designed by following Ward’s clustering method and the estimation of distances between each pair of H.pylori isolates was calculated with the squared Euclidean distance.RESULTS:Resistance rates were 4%for amoxicillin and 2.7%for clarithromycin with 2%double resistances.Genotyping evidenced a high prevalence of the genotype cagA-positive/vacA s1m1.The 3’region of cagA gene was successfully amplified in 92.3%(12/13)of the baseline resistant isolates and in 60%(36/60)of the resistant isolates growing in antibiotic dilutions.Upon observing the distribution of the number of EPIYA repetitions in each dilution with respect to baseline isolates,it was found that in 61.5%(8/13)of the baseline isolates,a change in the number of EPIYA repetitions lowered antibiotic pressure.The gain and loss of EPIYA motifs resulted in a diversity of H.pylori subclones after bacterial adjustment to changing conditions product of antibiotic pressure.RAPD PCR evidenced the close clonal relationship between baseline isolates and isolates growing in antibiotic dilutions.CONCLUSION:Antibiotic pressure does not induce loss of the cag pathogenicity island,but it can leadin most cases-to genetic rearrangements within the3’region cagA of the founding bacteria that can affect the level of tyrosine phosphorylation impacting on its cellular effects and lead to divergence of cagA-positive subclones.
基金Sponsored by Hainan Innovation Scientific Research Program of Graduates(hys2011-23)
文摘From the perspectives of hotel road profile,orientation of plant color combination,interpretation of Cultural eco-elements,and landscape design of Embrace Sea Villas Hotel was taken for example to explore the ways of demonstrating regional cultural characteristics in hotel landscape designs on Hainan Island. Eco-design techniques of tropical landscapes were combined to facilitate the formation of harmonious holiday resort images on the island,and enhance the public acceptance of the characteristic vacation culture of Hainan.