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天然抗氧化剂Isoverbascoside诱导人胃癌MGC 803细胞分化作用研究 被引量:4
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作者 陈瑞川 苏金华 +2 位作者 蔡克瑕 付永贵 李力 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2001年第4期936-942,共7页
人胃癌 MGC80 3细胞经天然抗氧化剂 Isoverbascoside(1sov)处理后 ,细胞生长和增殖呈现Isov浓度和处理时间依赖性抑制 ,群体倍增时间也相应延长 ;2 0 μmol/ L Isov处理可使细胞形态和超微结构发生正常化变化 ,集落形成率受抑 ;胃癌分... 人胃癌 MGC80 3细胞经天然抗氧化剂 Isoverbascoside(1sov)处理后 ,细胞生长和增殖呈现Isov浓度和处理时间依赖性抑制 ,群体倍增时间也相应延长 ;2 0 μmol/ L Isov处理可使细胞形态和超微结构发生正常化变化 ,集落形成率受抑 ;胃癌分化标志酶碱性磷酸酶和乳酸脱氢酶活性均呈时间依赖性下降 ,周期表现为 G1期阻滞 .表明 Isov具有诱导 MGC 80 3细胞分化的作用 。 展开更多
关键词 抗氧化剂 胃癌细胞 诱导分化 isoverbascoside
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Antifungal activity of total and fractionated phenolic extracts from two wild edible herbs 被引量:1
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作者 Maria Antonia Gatto Simona Marianna Sanzani +4 位作者 Piero Tardia Vito Linsalata Mariax Pieralice Lucrezia Sergio Donato Di Venere 《Natural Science》 2013年第8期895-902,共8页
The chemical characterization of phenolic extracts of salad burnet (Sanguisorba minor Scop. s.l.) and broomrape (Orobanche crenata Forsk.) was performed. Active fractions were separated and characterized and, in the c... The chemical characterization of phenolic extracts of salad burnet (Sanguisorba minor Scop. s.l.) and broomrape (Orobanche crenata Forsk.) was performed. Active fractions were separated and characterized and, in the case of O. crenata, two phenolic compounds, verbascoside and is overbascoside, were quantitatively extracted, purified and characterized. These compounds proved to be effective in reducing the growth of some important fungi responsible for the decay of fresh fruit and vegetables in postharvest. Verbascoside showed significant activity against Penicillium italicum, fairly inhibited Monilinia laxa, P. expansum, and Aspergillus carbonarius, and showed little activity against Botrytis cinerea, M. fructicola and P. digitatum. Isoverbascoside completely inhibited B. cinerea, P. digitatum, P. italicum, and P. expansum;it fairly inhibited M. laxa and A. carbonarius;while it showed to be less effective against M. fructicola. The obtained results support the possible use of some wild edible plants as a source of phenolic substances for the postharvest biological control of fresh fruit and vegetable rots. 展开更多
关键词 Antimicrobials POSTHARVEST Rot Storage PHENOLS VERBASCOSIDE isoverbascoside HPLC FLC
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