In this special issue of Neuroscience Bulletin, the topics range over emerging techniques from the nanoscopic to the macroscopic scales. At the nanoscopic level, new ways to obtain images at the individual protein le...In this special issue of Neuroscience Bulletin, the topics range over emerging techniques from the nanoscopic to the macroscopic scales. At the nanoscopic level, new ways to obtain images at the individual protein level in synapses take the re- construction of synaptic architecture to a new level, while using chromophores to disable specific proteins at selected subcellular locations allows the assessment of their functional roles in such dynamic processes as growth-cone extension and cell division. The subtle influences of axonal chan- nels and receptors on neurotransmission are revealed by recording from the blebs induced by axotomy, while methods from cloning to chemical computation are being applied to dissecting the structural-functional rules by which ion channels operatet41.展开更多
文摘In this special issue of Neuroscience Bulletin, the topics range over emerging techniques from the nanoscopic to the macroscopic scales. At the nanoscopic level, new ways to obtain images at the individual protein level in synapses take the re- construction of synaptic architecture to a new level, while using chromophores to disable specific proteins at selected subcellular locations allows the assessment of their functional roles in such dynamic processes as growth-cone extension and cell division. The subtle influences of axonal chan- nels and receptors on neurotransmission are revealed by recording from the blebs induced by axotomy, while methods from cloning to chemical computation are being applied to dissecting the structural-functional rules by which ion channels operatet41.
