Degeneration of joint disease is one of the problems that threaten global public health.Currently,the therapies of the disease are mainly conservative but not very effective.To solve the problem,we need to find effect...Degeneration of joint disease is one of the problems that threaten global public health.Currently,the therapies of the disease are mainly conservative but not very effective.To solve the problem,we need to find effective,convenient and inexpensive therapies.With the rapid development of artificial intelligence,we innovatively propose to combine Traditional Chinese Medicine(TCM)with artificial intelligence to design a rehabilitation assessment system based on TCM Daoyin.Our system consists of four subsystems:the spine movement assessment system,the posture recognition and correction system,the background music recommendation system,and the physiological signal monitoring system.We incorporate several technologies such as keypoint detection,posture estimation,heart rate detection,and deriving respiration from electrocardiogram(ECG)signals.Finally,we integrate the four subsystems into a portable wireless device so that the rehabilitation equipment is well suited for home and community environment.The system can effectively alleviate the problem of an inadequate number of physicians and nurses.At the same time,it can promote our TCM culture as well.展开更多
Autologous fat-derived stromal vascular fraction(SVF) is a mixed cell population that has been used for many years in regenerative plastic surgery.In terms of animal and clinical research,this concise review was perfo...Autologous fat-derived stromal vascular fraction(SVF) is a mixed cell population that has been used for many years in regenerative plastic surgery.In terms of animal and clinical research,this concise review was performed to evaluate the efficacy of SVF in knee degenerative joint disease(KDJD),which could cause pain,disability and severely affect patients’ lives.Thirteen studies retrieved and screened from the databases were included,including six animal studies and seven clinical trials.The metaanalysis of clinical research shows that intra-articular injection of SVF,in combination with adjuvant surgery,could alleviate pain and improve early functional recovery for patients with KDJD at Kellgren-Lawrence(KL) grades Ⅱ–Ⅲ.展开更多
Objective To investigate the clinical outcomes of trans-facet joints approach to treat thoracic degenerative disease with anterior compression.Methods From January 2003 to December 2009,22 patients with thoracic myelo...Objective To investigate the clinical outcomes of trans-facet joints approach to treat thoracic degenerative disease with anterior compression.Methods From January 2003 to December 2009,22 patients with thoracic myelopathy caused by展开更多
BACKGROUND Limb length discrepancy(LLD)after total knee arthroplasty(TKA)has been considered as one of the reasons for the unsatisfactory outcome.However,there is no consensus about the extent of LLD that can be consi...BACKGROUND Limb length discrepancy(LLD)after total knee arthroplasty(TKA)has been considered as one of the reasons for the unsatisfactory outcome.However,there is no consensus about the extent of LLD that can be considered as clinically relevant.AIM To evaluate the incidence of radiographic LLD and its impact on functional outcome following TKA.METHODS All randomized-controlled trial and observational studies on LLD in TKA,published till 22nd June 2020,were systematically searched and reviewed.The primary outcome was“limb lengthening or LLD after TKA”.The secondary outcomes included“assessment of LLD in varus/valgus deformity”and“impact of LLD on the functional outcome”.RESULTS Of 45 retrieved studies,qualitative and quantitative assessment of data was performed from eight studies and six studies,respectively.Five studies(n=1551)reported the average limb lengthening of 5.98 mm.The LLD after TKA was ranging from 0.4±10 mm to 15.3±2.88 mm.The incidence of postoperative radiographic LLD was reported in 44%to 83.3%of patients.There was no difference in the preoperative and postoperative LLD(MD-1.23;95%CI:-3.72,1.27;P=0.34).Pooled data of two studies(n=219)revealed significant limb lengthening in valgus deformity than varus(MD-2.69;95%CI:-5.11,0.27;P=0.03).The pooled data of three studies(n=611)showed significantly worse functional outcome in patients with LLD of≥10 mm compared to<10 mm(standard MD 0.58;95%CI:0.06,1.10;P=0.03).CONCLUSION Limb lengthening after TKA is common,and it is significantly more in valgus than varus deformity.Significant LLD(≥10 mm)is associated with suboptimal functional outcome.展开更多
A long-span concrete-filled steel tubular(CFST)arch bridge suffers severe vehicle-induced dynamic responses during its service life.However,few quantitative studies have been reported on the typical diseases suffered ...A long-span concrete-filled steel tubular(CFST)arch bridge suffers severe vehicle-induced dynamic responses during its service life.However,few quantitative studies have been reported on the typical diseases suffered by such bridges and their effects on vehicle-induced dynamic response.Thus,a series of field tests and theoretical analyses were conducted to study the effects of typical diseases on the vehicle-induced dynamic response of a typical CFST arch bridge.The results show that a support void results in a height difference between both sides of the expansion joint,thus increasing the effect of vehicle impact on the main girder and suspenders.The impact factor of the displacement response of the main girder exceeds the design value.The variation of the suspender force is significant,and the diseases are found to have a greater effect on a shorter suspender.The theoretical analysis results also show that the support void causes an obvious longitudinal displacement of the main girder that is almost as large as the vertical displacement.The support void can also cause significant changes in the vehicle-induced acceleration response,particularly when the supports and steel box girder continue to collide with each other under the vehicle load.展开更多
基金National Key R&D Program of China(No.2019YFC1711800,2020AAA0108300)National Natural Science Founda⁃tion of China(No.62072112)Fudan University-CIOMP Joint Fund(No.FC2019-005).
文摘Degeneration of joint disease is one of the problems that threaten global public health.Currently,the therapies of the disease are mainly conservative but not very effective.To solve the problem,we need to find effective,convenient and inexpensive therapies.With the rapid development of artificial intelligence,we innovatively propose to combine Traditional Chinese Medicine(TCM)with artificial intelligence to design a rehabilitation assessment system based on TCM Daoyin.Our system consists of four subsystems:the spine movement assessment system,the posture recognition and correction system,the background music recommendation system,and the physiological signal monitoring system.We incorporate several technologies such as keypoint detection,posture estimation,heart rate detection,and deriving respiration from electrocardiogram(ECG)signals.Finally,we integrate the four subsystems into a portable wireless device so that the rehabilitation equipment is well suited for home and community environment.The system can effectively alleviate the problem of an inadequate number of physicians and nurses.At the same time,it can promote our TCM culture as well.
基金supported by the National Natural Science Foundation of China (81974347)the National Clinical Research Center for Geriatrics,West China Hospital Sichuan University(Z2021JC002)the “1.3.5 Program for Disciplines of Excellence”,West China Hospital,Sichuan University (ZYJC18002,2018HXFH040)。
文摘Autologous fat-derived stromal vascular fraction(SVF) is a mixed cell population that has been used for many years in regenerative plastic surgery.In terms of animal and clinical research,this concise review was performed to evaluate the efficacy of SVF in knee degenerative joint disease(KDJD),which could cause pain,disability and severely affect patients’ lives.Thirteen studies retrieved and screened from the databases were included,including six animal studies and seven clinical trials.The metaanalysis of clinical research shows that intra-articular injection of SVF,in combination with adjuvant surgery,could alleviate pain and improve early functional recovery for patients with KDJD at Kellgren-Lawrence(KL) grades Ⅱ–Ⅲ.
文摘Objective To investigate the clinical outcomes of trans-facet joints approach to treat thoracic degenerative disease with anterior compression.Methods From January 2003 to December 2009,22 patients with thoracic myelopathy caused by
文摘BACKGROUND Limb length discrepancy(LLD)after total knee arthroplasty(TKA)has been considered as one of the reasons for the unsatisfactory outcome.However,there is no consensus about the extent of LLD that can be considered as clinically relevant.AIM To evaluate the incidence of radiographic LLD and its impact on functional outcome following TKA.METHODS All randomized-controlled trial and observational studies on LLD in TKA,published till 22nd June 2020,were systematically searched and reviewed.The primary outcome was“limb lengthening or LLD after TKA”.The secondary outcomes included“assessment of LLD in varus/valgus deformity”and“impact of LLD on the functional outcome”.RESULTS Of 45 retrieved studies,qualitative and quantitative assessment of data was performed from eight studies and six studies,respectively.Five studies(n=1551)reported the average limb lengthening of 5.98 mm.The LLD after TKA was ranging from 0.4±10 mm to 15.3±2.88 mm.The incidence of postoperative radiographic LLD was reported in 44%to 83.3%of patients.There was no difference in the preoperative and postoperative LLD(MD-1.23;95%CI:-3.72,1.27;P=0.34).Pooled data of two studies(n=219)revealed significant limb lengthening in valgus deformity than varus(MD-2.69;95%CI:-5.11,0.27;P=0.03).The pooled data of three studies(n=611)showed significantly worse functional outcome in patients with LLD of≥10 mm compared to<10 mm(standard MD 0.58;95%CI:0.06,1.10;P=0.03).CONCLUSION Limb lengthening after TKA is common,and it is significantly more in valgus than varus deformity.Significant LLD(≥10 mm)is associated with suboptimal functional outcome.
基金This research was supported by the National Natural Science Foundation of China(Grant Nos.51908015,51978021)National Key Research and Development Program of China(Grant Nos.2017YFC1500604,2017YFC1500603)+1 种基金Beijing Municipal Education Commission(Nos.KM201910005020,IDHT20190504)the Basic Research Fund of Beijing University of Technology(No.004000546318524).
文摘A long-span concrete-filled steel tubular(CFST)arch bridge suffers severe vehicle-induced dynamic responses during its service life.However,few quantitative studies have been reported on the typical diseases suffered by such bridges and their effects on vehicle-induced dynamic response.Thus,a series of field tests and theoretical analyses were conducted to study the effects of typical diseases on the vehicle-induced dynamic response of a typical CFST arch bridge.The results show that a support void results in a height difference between both sides of the expansion joint,thus increasing the effect of vehicle impact on the main girder and suspenders.The impact factor of the displacement response of the main girder exceeds the design value.The variation of the suspender force is significant,and the diseases are found to have a greater effect on a shorter suspender.The theoretical analysis results also show that the support void causes an obvious longitudinal displacement of the main girder that is almost as large as the vertical displacement.The support void can also cause significant changes in the vehicle-induced acceleration response,particularly when the supports and steel box girder continue to collide with each other under the vehicle load.