Exploring Daxing Development Foreign journalists' tour of Beijing's Daxing District

Under the watchful eyes of fellow journalists,Si Thu Tun from Myanmar inserted a slender catheter into a model human skull to experience a neurosurgeon using the MRguided laser ablation system to treat a patient with epilepsy.Other journalists were also quite interested in the procedure.They took over from Si Thu and created short videos for their social media accounts.

Journal Club教学法用于临床药学专业硕士研究生理论教学实践

目的探讨Journal Club教学法在临床药学专业硕士研究生理论教学中的应用效果。方法选取重庆医科大学2022年的2020级(4名)、2021级(6名)临床药学专业硕士研究生为研究对象。课前,2个年级的学生分别以小组为单位,围绕与“临床药物治疗学前沿”授课内容相关的2个临床用药问题,通过设定关键词、检索文献、分析评价、证据分级,制订最优用药方案;课中以幻灯片形式分享经典文献,并对最优用药方案进行循证药学证据分析。采用匿名问卷调查法统计对该教学法8个条目完全赞同、基本同意及否定的人数,并计算占比;授课教师对学生撰写的综述进行评分(90~100分、80~89分、70~79分、60~69分分别为优、良、中、及格);统计学生通过本轮教学的论文发表情况。结果2020级、2021级分别发放调查问卷4份、6份,均全部回收,有效回收率均为100.00%;对所有调查项目均完全赞同或基本同意的分别有29人次、47人次。期末考试成绩为优、良、中的,2020级分别有2名(50.00%)、1名(25.00%)、1名(25.00%),优良率为75.00%;2021级分别有2名(33.33%)、3名(50.00%)、1名(16.67%),优良率为83.33%。2021级学生有1篇综述发表在科学引文索引(SCI)期刊上。结论Journal Club教学法有助于提高学生的文献查阅能力和英文阅读能力,可调动自主学习的积极性,增强独立思考能力和科研创新意识。

GAMYB transcription factor LoMYB65 from lily plays a vital role in pollen development

Lily(Lilium spp.)is an important horticultural crop,but its use is limited due to serious pollen contamination problems.There are many studies on pollen development in model plants,but few on flower crops such as lilies.Gibberellin(GA)is a large class of hormones and plays an important role in plant vegetative growth and reproductive development.GAMYB is a group of the R2R3-MYB family upregulated by gibberellin,and plays an important role in anther development.Here,we isolated a novel GAMYB,named LoMYB65,from lily,which was closely related to the AtMYB65 and AtMYB33 in Arabidopsis.Fluorescence quantitative PCR results showed that LoMYB65 was mainly expressed in lily anthers.LoMYB65 could be activated by 288μmol·L^(-1)GA3treatment and the LoMYB65 protein was located in the nucleus and cytoplasm,and had transactivation in yeast and tobacco leaf cells.The conserved motif within 226 amino acids of the C-terminal of LoMYB65 contributed to its transactivation.Overexpression of LoMYB65 caused dwarf phenotype,unnormal tapetum development,less seeds of siliques in transgenic Arabidopsis plants,the transgenic plants showed partly male sterile.Simultaneously,silencing of LoMYB65 with VIGS(Virus Induced Gene Silencing)in lily anthers caused unnormal pollen development and reduced the pollen amount.Overexpression of LoMYB65 in Arabidopsis and silencing of LoMYB65 in lily resulted in decreased pollen counts,so we speculate that LoMYB65 may be dose-dependent.Overall,these findings suggest that LoMYB65 may play an important role in anther development and pollen formation in lily.LoMYB65 may provide a useful candidate gene for pollenless breeding of lily.

Conventional Geothermal Systems and Unconventional Geothermal Developments: An Overview

This paper provides an overview of conventional geothermal systems and unconventional geothermal developments as a common reference is needed for discussions between energy professionals. Conventional geothermal systems have the heat, permeability and fluid, requiring only drilling down to °C, normal heat flow or decaying radiogenic granite as heat sources, and used in district heating. Medium-temperature (MT) 100°C - 190°C, and high-temperature (HT) 190°C - 374°C resources are mostly at plate boundaries, with volcanic intrusive heat source, used mostly for electricity generation. Single well capacities are °C - 500°C) and a range of depths (1 m to 20 Km), but lack permeability or fluid, thus requiring stimulations for heat extraction by conduction. HVAC is 1 - 2 m deep and shallow geothermal down to 500 m in wells, both capturing °C, with °C are either advanced by geothermal developers at <7 Km depth (Enhanced Geothermal Systems (EGS), drilling below brittle-ductile transition zones and under geothermal fields), or by the Oil & Gas industry (Advanced Geothermal Systems, heat recovery from hydrocarbon wells or reservoirs, Superhot Rock Geothermal, and millimeter-wave drilling down to 20 Km). Their primary aim is electricity generation, relying on closed-loops, but EGS uses fractures for heat exchange with earthquake risks during fracking. Unconventional approaches could be everywhere, with shallow geothermal already functional. The deeper and hotter unconventional alternatives are still experimental, overcoming costs and technological challenges to become fully commercial. Meanwhile, the conventional geothermal resources remain the most proven opportunities for investments and development.

Development and technology status of energy storage in depleted gas reservoirs

Utilizing energy storage in depleted oil and gas reservoirs can improve productivity while reducing power costs and is one of the best ways to achieve synergistic development of"Carbon Peak–Carbon Neutral"and"Underground Resource Utiliza-tion".Starting from the development of Compressed Air Energy Storage(CAES)technology,the site selection of CAES in depleted gas and oil reservoirs,the evolution mechanism of reservoir dynamic sealing,and the high-flow CAES and injection technology are summarized.It focuses on analyzing the characteristics,key equipment,reservoir construction,application scenarios and cost analysis of CAES projects,and sorting out the technical key points and existing difficulties.The devel-opment trend of CAES technology is proposed,and the future development path is scrutinized to provide reference for the research of CAES projects in depleted oil and gas reservoirs.

BMPRⅡ^(+)neural precursor cells isolated and characterized from organotypic neurospheres:an in vitro model of human fetal spinal cord development

Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not well understood.Type-ⅡBMP receptor(BMPRⅡ),the cognate receptor,is expressed by neural precursor cells during embryogenesis;however,an in vitro method of enriching BMPRⅡ^(+)human neural precursor cells(hNPCs)from the fetal spinal cord is absent.Immunofluorescence was undertaken on intact second-trimester human fetal spinal cord using antibodies to BMPRⅡand leukemia inhibitory factor(LIF).Regions of highest BMPRⅡ^(+)immunofluorescence localized to sensory columns.Parenchymal and meningeal-associated BMPRⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage markers,CD34/CD39.LIF immunostaining identified a population of somas concentrated in dorsal and ventral horn interneurons,mirroring the expression of LIF receptor/CD118.A combination of LIF supplementation and high-density culture maintained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,cytoarchitecture.These neurospheres were characterized by BMPRⅡ^(+)/MAP2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vimentin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vimentin^(+)/GFAP^(+)/MAP2ab^(–)/NeuN^(–)multipotent precursors.Dissociated cultures from tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage cells.Fluorescence-activated cell sorting-sorted BMPRⅡ^(+)hNPCs were MAP2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in culture.This is the first isolation of BMPRⅡ^(+)hNPCs identified and characterized in human fetal spinal cords.Our data show that LIF combines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterized by surface BMPRⅡ^(+)hNPCs.Our study has provided a new methodology for an in vitro model capable of amplifying human fetal spinal cord cell numbers for>10 passages.Investigations of the role BMPRⅡplays in spinal cord development have primarily relied upon mouse and rat models,with interpolations to human development being derived through inference.Because of significant species differences between murine biology and human,including anatomical dissimilarities in central nervous system(CNS)structure,the findings made in murine models cannot be presumed to apply to human spinal cord development.For these reasons,our human in vitro model offers a novel tool to better understand neurodevelopmental pathways,including BMP signaling,as well as spinal cord injury research and testing drug therapies.

Journal of Integrative Agriculture(JIA) Instruction to Authors

Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(AsC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAAsS).JIAis a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.CAAS President,Academician WU Kong-ming is the Chairman of the Board,and CAAS Vice President,Academician CHEN Hua-lan is the Editor-in-Chief.JIA has been published by Elsevier B.V.since 2006 and is a leading academic journal in agricultural sciences in China.As released by JCR,the latest IF of the journal is 4.8.

Journal of Integrative Agriculture (JIA) Instruction to Authors

Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(AsC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAAss).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.CAAs President,Academician WU Kong-ming is the Chairman of the Board,and CAAS Vice President,Academician CHEN Hua-lan is the Editor-in-Chief.JIA has been published by Elsevier B.V.since 2006 and is a leading academic journal in agricultural sciences in China.As released by JCR,the latest IF of the journal is 4.8.

Call for Papers from Journal of Future Foods

Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.

Journal of Integrative Agriculture(JIA)Instruction to Authors

Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(AsC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAASS).JIAis a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.

Journal of Sport and Health Science Guide for Authors

Aims The Journal of Sport and Health Science(JSHS)is a peer-reviewed,international,multidisciplinary scientific journal dedicated to the advancement of sport,exercise,physical activity,and health sciences.JSHS publishes original and impactful research,topical reviews,editorials,opinion,and commentary papers relating physical and mental health,injury and disease prevention,traditional Chinese exercise,and human performance.Through a distinguished,carefully selected international editorial board,JSHS has adopted the highest academic standards,impeccable integrity,and an efficient publication platform.

Journal of Sport and Health Science Guide for Authors

Aims The Journal of Sport and Health Science(JSHS)is a peer-reviewed,international,multidisciplinary scientific journal dedicated to the advancement of sport,exercise,physical activity,and health sciences.JSHS publishes original and impactful research,topical reviews,editorials,opinion,and commentary papers relating physical and mental health,injury and disease prevention,traditional Chinese exercise,and human performance.Through a distinguished,carefully selected international editorial board,JSHS has adopted the highest academic standards,impeccable integrity,and an efficient publication platform.

Journal of Integrative Agriculture (JIA) Instruction to Authors

Description Journal of Integrative Agriculture(JIA),formerly Agricultural Sciences in China(AsC),founded in 2002,is sponsored by Chinese Academy of Agricultural Sciences(CAAS),co-sponsored by Chinese Association of Agricultural Science Societies(CAAsS).JIA is a peer-reviewed and multi-disciplinary international journal and published monthly in English.JIA'Editorial Board consists of 289 well-respected scholars of agricultural scientific fields.CAAs President,Academician WU Kong-ming is the Chairman of the Board,and CAAS Vice President,Academician CHEN Hua-lan is the Editor-in-Chief.JIA has been published by Elsevier B.V.since 2006 and is a leading academic journal in agricultural sciences in China.As released by JCR,the latest IF of the journal is 4.8.

Journal of Sport and Health Science Guide for Authors

Please visit https://www.sciencedirect.com/journal/journal-of-sport-and-health-science for the detailed version of Guide for Authors.Aims The Journal of Sport and Health Science (JSHS) is a peer-reviewed,international,multidisciplinary scientific journal dedicated to the advancement of sport,exercise,physical activity,and health sciences.JSHS publishes original and impactful research,topical reviews,editorials,opinion,and commentary papers relating physical and mental health,injury and disease prevention,traditional Chinese exercise,and human performance.Through a distinguished,carefully selected international editorial board,JSHS has adopted the highest academic standards,impeccable integrity,and an efficient publication platform.

Journal of Sport and Health Science Guide for Authors

Please visit https://www.sciencedirect.com/journal/journal-of-sport-and-health-science for the detailed version of Guide for Authors.Aims The Journal of Sport and Health Science(JSHS)is a peer-reviewed,international,multidisciplinary scientific journal dedicated to the advancement of sport,exercise,physical activity,and health sciences.JSHS publishes original and impactful research,topical reviews,editorials,opinion,and commentary papers relating physical and mental health,injury and disease prevention,traditional Chinese exercise,and human performance.Through a distinguished,carefully selected international editorial board,JSHS has adopted the highest academic standards,impeccable integrity,and an efficient publication platform.

Call for Papers from Journal of Future Foods

Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.

Call for Papers from Journal of Future Foods

Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.

Journal Introduction:China Finance Review International

Background The China Finance Review International is a flagship academic journal broadly covering the Chinese and international financial markets.The journal is founded by Antai College of Economics and Management at Shanghai Jiao Tong University,one of the top universities in Asia.The China Finance Review International aims to publish quality empirical and theoretical works on important financial and economic issues in the profession.We encourage ground-breaking research related to new and niche areas in finance,such as Fintech and cryptos,ESG,climate finance,and socially responsible investments.We welcome critiques of existing literature and comparative analysis between emerging markets and developed economies.

Call for Papers from Journal of Future Foods

Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.

Call for Papers from Journal of Future Foods

FoodsJournal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.